scholarly journals The Effect of Ginger Extract (zingiber officinale roscoe) on the Number of Neutrophil Cells, Fibroblast and Epithelialization on Incision Wound

2020 ◽  
Vol 1569 ◽  
pp. 032063
Author(s):  
K I N Rahayu ◽  
I P S Suharto ◽  
A N Etika ◽  
S E Nurseskasatmata
2010 ◽  
Vol 6 (1) ◽  
pp. 36
Author(s):  
Silvana Dinaintang Harikedua

The objective of this study was to investigate the effect of ginger extract addition and refrigerate storage on sensory quality of Tuna through panelist’s perception. Panelists (n=30) evaluated samples for overall appearance and flavor attribute using hedonic scale 1–7. The sample which is more acceptable by panelists on flavor attributes having 3% gingers extract and storage for 3 days. The less acceptable sample on flavor attribute having 0% ginger extract and storage for 9 days. On the other hand, the sample which is more acceptable by panelists on overall appearance having 0% ginger extract without storage treatment. The less acceptable sample on overall appearance having 3% ginger extract and storage for 9 days.


Author(s):  
Shavilla Lukita ◽  
Winda Khosasi ◽  
Chandra Susanto ◽  
Florenly

Red ginger extract has a category strong antibacterial effect on Staphylococcusaureus and Streptococcus mutans. Red ginger essential oil has the potential forstronger inhibition. This study aims to compare the antibacterial effectiveness of redginger essential oil against Staphylococcus aureus and Streptococcus mutans. Thedesign of this study was a laboratory experimental design with a factorial completelyrandomized design. The red ginger used in this study was proven to be a species ofZingiber officinale Roscoe. The production of essential oils in this study uses thesteam distillation method. The content of secondary metabolites in red ginger wastested quantitatively by the GC-MS method. Determination of antibacterial activityusing the disc diffusion method. The data were processed using the SPSS 21.0program. The normality of data distribution was tested with the Shapiro-Wilk test,followed by one-way ANOVA, Levene's test, and the Tukey HSD Post Hoc Test. Theresults of the antibacterial test of red ginger essential oil against Staphylococcusaureus (21.21mm ± 0.315) and Streptoococcus mutans (23.43mm ± 0.189) provedthat the inhibition power of the category was very strong at a concentration of 75%.


2018 ◽  
Vol 2 (2) ◽  
pp. 31-41
Author(s):  
Chairil Anwar ◽  
KM Yahya Syukur ◽  
Dalilah Dalilah ◽  
Salni Salni ◽  
Novrikasari Novrikasari

Aedes aegypti is a vector of Dengue Hemoragic Fever. The use of synthetic chemical insecticide is the most common way to control Ae. aegypti. However, since it can cause resistency if it is used in a wide scale with high frequency and continously, it requires an alternative way. Red ginger (Zingiber officinale Roscoe var. rubrum) is one of natural insecticide which is safe to be used to control Ae. aegypti. This research aims was to determine the activity of active fraction of red ginger to mortality of Ae. aegypti. It was a quasi-experiment research with post test only control design. Twenty Ae. aegypti Liverpool strain were the sample of this research with 5 concentration for each and 4 times repetition. The result showed that concentration 0.5%, 1.0%, 1.5%, 2.0% and 2.5% causing mortality percentage of 32.5%, 33.8%, 51.3%, 58.8% and 65.0% respectively. One way Anova test showed p-value < alpha ± (0.00 < 0.05). It was concluded that there was a significant difference of various concentration of active fraction n-heksan of red ginger extract to the mortality of Ae. aegypti. The lethal concentration (LC50) was 2.409%. It was suggested to continue this research with reppellant or bio-assay test method.   Key words: Toxicity, extract, fraction, Aedes aegypti, Insecticidal


Author(s):  
Suci Rizkia Amalia ◽  
Iis Rostini ◽  
Mega Laksmini Syamsuddin ◽  
Rusky Intan Pratama

Eucheuma cottonii is one of seaweed species that has beneficial economic value and widely cultivated in Indonesia. Diversifying product into seaweed jelly candy could be carried out to utilize the source. The seaweed distinctive aroma is one of problem in producing jelly candy. Ingredient with strong aroma such as red ginger is needed to covered the smell. This research was aimed to determine the optimum concentration of red ginger (Zingiber officinale Roscoe) extract and seaweed (Eucheuma cottonii) to produce high quality jelly candy based on chemical and organoleptic characteristics. This research used an experimental method consisting of 4 different concentration of red ginger extract (0%, 40%, 50% and 60%) with 20 panelists as evaluators. Chemical composition (water content, protein content, fat content, carbohydrate content, crude fiber content) and organoleptic characteristics (appearance, aroma, texture, taste) of jelly candy were observed as parameters in this research. The results showed that the addition of 50% red ginger extract to jelly candy produced the best organoleptic characteristics and most preferred by panelists. The chemical analysis showed the jelly candy contained 6,22% water, 0,88% protein, 0,19% fat, 96,82% carbohydrate, and 1,54% crude fiber. Addition 50% of red ginger extract is recommended to produce seaweed jelly candy that has the best and most preferred characteristics.


2018 ◽  
Vol 25 (4) ◽  
pp. 160
Author(s):  
Kusumarn Noipha ◽  
Putrada Ninla-Aesong

  The potential roles of Zingiber officinale Roscoe (ginger) for treating and preventing diabetes have been investigated in both humans and experimental animals. However, the mode of its action has not yet been elucidated. This study aimed to investigate the effects of ginger extract on glucose uptake activity and its activation pathway in L6 myotubes. Cells were co-cultured for 24 h with a variable concentration of either ginger extract or 2 mM metformin or 200 nM insulin or 20 μM Troglitazone (TGZ), followed by a 10-min 2-[3H]-deoxy-D-glucose (2-DG) uptake. The levels of glucose transporters 1 (GLUT1) and GLUT4 protein and mRNA expression were determined. Ginger extract at 400 μg/ml significantly enhanced glucose uptake in L6 myotubes (208.03 ± 10.65% above basal value, p<0.05) after co-culture for 24 h. The ginger-enhancement of glucose uptake was inhibited by 3.5 μM cycloheximide, a protein synthesis inhibitor, 1 μM wortmannin (Phosphatidylinositol 3-Kinase (PI3 kinase) inhibitor) and 15 nM rapamycin (mammalian target of rapamycin (mTOR) inhibitor). The enhancement of glucose transport by ginger extract at 400 μg/ml was accompanied with the increased expression of GLUT1 protein (1.60 ± 0.20, 2.03 ± 0.19, and 2.25 ± 0.35 folds of basal at 4, 8, and 24 h, respectively p<0.05) and mRNA (1.22 ± 0.96, 1.45 ± 0.93, 1.91 ± 0.75, 2.32±0.92, and 2.20 ± 0.64 folds of basal at 1, 2, 4, 8, and 24 h, respectively p<0.05) in a time-dependent manner. Z. officinale Roscoe rhizome extract increase glucose transport activity of L6 myotubes by enhancing GLUT1 expression, the results of PI3-Kinase and 5’-AMP-activated kinase (AMPK) stimulation.


Food Research ◽  
2021 ◽  
Vol 5 (5) ◽  
pp. 236-243
Author(s):  
A. Sharizan ◽  
A.M. Sahilah

Zingiber officinale Roscoe var. Bentong or locally known as Bentong ginger is exclusively planted and harvested in the district of Bentong, Pahang, Malaysia. The demand for this ginger species has dramatically increased due to its high food and medicinal values, owing to the presence of 6-shogaol and 6-gingerol as active compounds. This study aimed to measure the concentrations of those active compounds with respect to their one-year plantation duration (January - December 2018). The proximate analysis, heavy metals and antioxidant activity were simultaneously determined during the plant growth. 6-gingerol was present in both fresh and dried samples whilst 6-shogaol could only be found in dried samples. Fresh ginger recorded the highest 6-gingerol content (2.09 mg/g) in the seventh month of harvesting time. On the other hand, in the sixth month of harvesting time, dried ginger had the highest concentration of 6-gingerol (0.66 mg/g) and 6-shogaol (1.85 mg/g). Notably, the accumulation of heavy metals such as As, Pb, Cd and Hg in Bentong ginger was relatively low and within the permissible limit. Meanwhile, the total polyphenol and phenolic content of Bentong ginger extract solution were observed to decrease as the ginger was maturing. In conclusion, Z. officinale Roscoe var. Bentong yielded different amounts of active compounds with respect to its harvesting time. Nevertheless, it generally exhibits good values in terms of chemical compositions that can be potentially used as nutraceutical food.


2017 ◽  
Vol 204 (5-6) ◽  
pp. 241-250 ◽  
Author(s):  
Azam Hosseinzadeh ◽  
Kobra Bahrampour Juybari ◽  
Mohammad Javad Fatemi ◽  
Tunku Kamarul ◽  
Aboulfazl Bagheri ◽  
...  

Aims: The protective effects of ginger (Zingiber officinale Roscoe) extract on IL-1β-mediated oxidative stress and mitochondrial apoptosis were investigated in C28I2 human chondrocytes. Methods: The effects of various concentrations of ginger extract on C28I2 human chondrocyte viability were evaluated in order to obtain noncytotoxic concentrations of the drug by methylthiotetrazole assay. The cells were pretreated with 5 and 25 μg/mL ginger extract for 24 h, followed by incubation with IL-1β (10 ng/mL) for 24 h. The effects of ginger extract on IL-1β-induced intracellular reactive oxygen species (ROS) production and lipid peroxidation were examined. The mRNA expressions of antioxidant enzymes including catalase, superoxide dismutase-1, glutathione peroxidase-1, glutathione peroxidase-3, and glutathione peroxidase-4 were evaluated by reverse transcription polymerase chain reaction. The protein expressions of Bax, Bcl-2, and caspase-3 were analyzed by Western blotting. Results: No cytotoxicity was observed at any concentration of ginger extract in C28I2 cells. Ginger extract pretreatment remarkably increased the gene expression of antioxidant enzymes and reduced the IL-1β-induced elevation of ROS, lipid peroxidation, the Bax/Bcl-2 ratio, and caspase-3 activity. Conclusions: Ginger extract could considerably reduce IL-1β-induced oxidative stress and consequent mitochondrial apoptosis as the major mechanisms of chondrocyte cell death. These beneficial effects of ginger extract may be due to its antioxidant properties. It may be considered as a natural herbal product to prevent OA-induced cartilage destruction in the clinical setting.


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 853-858
Author(s):  
Subbarao K ◽  
Ganga Raju G ◽  
Kayalvizhi E ◽  
Sundaravadivel V.P.

This project work study was carried out the pharmacological screening of anxiolytic activity of methanolic extract of Zingiber officinale (ginger) rhizomes in the rat. Ginger is an antique therapeutic plant fitting to Zingiberoside family that is formally called as Zingiber officinale Rosc. The behavioral test was measuring by using the two anxiolytics represent actionlike raised plus maze (EPM) and light-dark arena model. The extraction of ginger is approved out by Soxhlet apparatus utilizing methanol as solvent. The ginger extract dose was administered in two groups as 200 mg/kg, p.o. which is compared with control (received vehicle) and standard groups (diazepam 1 mg/kg, i.p.) for its anxiolytic action for 7 days. The dose at 200 mg /kg and 400 mg/kg administered verbally which increase the time spent and no of entry in raised plus maze and growth time consumed inbox and no of crossing between light dark compartment boxes. The  consequences of the training work exposed by extracts exhibit anxiolytic activity. Those female-to-male proportion to At whatever lifetime tension issue may be 3:2. The majority uneasiness issue start over childhood, youthfulness What's more initial adulthood. Frenzy issue exhibits a bimodal period about onset in the age gatherings for 15-24 a considerable length of time. Furthermore, 45- 54 a considerable length of time.


Author(s):  
Эльвира Алексеевна Алексеева ◽  
О. Г. Димитров ◽  
Л. Н. Шантанова ◽  
С. М. Николаев ◽  
Е. Н. Карева ◽  
...  

Изучены адаптогенные свойства растительного средства «Кардекаим», представляющего собой сухой экстракт из сырья Inula helenium L., Zingiber officinale Roscoe, Elletaria cardamomum (L.) Maton., Caragana spinosa (L.) Wall. ex Hornem. и содержащего в качестве действующих веществ фенольные соединения и терпеноиды. Курсовое превентивное введение кардекаима в дозе 100 мг/кг в течение 7 дней перед острым эмоциональным стрессом оказывает выраженное стресс-протективное действие, препятствуя развитию признаков «триады Селье»: инволюции вилочковой железы (40 %), язвенным повреждениям слизистой оболочки желудка (в 5 раз) и в меньшей степени — гипертрофии надпочечников (p ≤ 0,05), полученный эффект не уступает препарату сравнения — экстракту элеутерококка. Показано, что повышение резистентности к стрессу под влиянием кардекаима сопровождается активацией синтеза белков теплового шока (Hsp-70), не связанной со стресс-индуцированной генерацией NO.


Sign in / Sign up

Export Citation Format

Share Document