Maternal Variants in the MFGE8 Gene are Associated with Perceived Breast Milk Supply

2021 ◽  
Author(s):  
Desirae Chandran ◽  
Alexandra Confair ◽  
Kaitlyn Warren ◽  
Yuka Imamura Kawasawa ◽  
Steven D. Hicks
Keyword(s):  
Breast Milk ◽  
Milk Supply

scholarly journals What Evidence Do We Have for Pharmaceutical Galactagogues in the Treatment of Lactation Insufficiency?—A Narrative Review

Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 974 ◽  
Author(s):  
Luke E. Grzeskowiak ◽  
Mary E. Wlodek ◽  
Donna T. Geddes
Keyword(s):  
Clinical Practice ◽  
Breast Milk ◽  
Milk Composition ◽  
Narrative Review ◽  
Pharmacological Intervention ◽  
Future Research ◽  
Individual Treatment ◽  
Efficacy And Safety ◽  
Milk Supply ◽  
Insufficient Milk

Inadequate breast milk supply is a frequently reported reason for early discontinuation of breastfeeding and represents a critical opportunity for intervening to improve breastfeeding outcomes. For women who continue to experience insufficient milk supply despite the utilisation of non-pharmacological lactation support strategies, pharmacological intervention with medications used to augment lactation, commonly referred to as galactagogues, is common. Galactagogues exert their pharmacological effects through altering the complex hormonal milieu regulating lactation, particularly prolactin and oxytocin. This narrative review provides an appraisal of the existing evidence regarding the efficacy and safety of pharmaceutical treatments for lactation insufficiency to guide their use in clinical practice. The greatest body of evidence surrounds the use of domperidone, with studies demonstrating moderate short-term improvements in breast milk supply. Evidence regarding the efficacy and safety of metoclopramide is less robust, but given that it shares the same mechanism of action as domperidone it may represent a potential treatment alternative where domperidone is unsuitable. Data on remaining interventions such as oxytocin, prolactin and metformin is too limited to support their use in clinical practice. The review provides an overview of key evidence gaps and areas of future research, including the impacts of pharmaceutical galactagogues on breast milk composition and understanding factors contributing to individual treatment response to pharmaceutical galactagogues.

Breastfeeding

2017 ◽  
Author(s):  
Janet Medforth ◽  
Linda Ball ◽  
Angela Walker ◽  
Sue Battersby ◽  
Sarah Stables
Keyword(s):  
Breast Milk ◽  
Infant Nutrition ◽  
Milk Supply ◽  
Breastfeeding Practices ◽  
Returning To Work ◽  
Common Problems ◽  
Insufficient Milk

This chapter considers all aspects of breastfeeding. The latest Baby Friendly Initiative standards are detailed, along with the advantages of, and contraindications to, breastfeeding. The constituents of breast milk and their role in infant nutrition are identified. Recently recognized changes in the structure of the lactating breasts are presented. There are detailed sections on the management and support of breastfeeding. Practices shown to be detrimental to successful breastfeeding are highlighted. Expression of breast milk and breastfeeding and returning to work are fully explained, as well as discontinuation of breastfeeding. Common problems encountered whilst breastfeeding are considered, including sore/cracked nipples, engorgement, blocked ducts, mastitis, breast refusal, insufficient milk supply, and Candida infection (thrush). Breastfeeding in special situations is also explored. The importance of correct nutrition and breastfeeding is reviewed.

scholarly journals PENGARUH SARI KURMA PADA IBU POSTPARTUM TERHADAP BERAT BADAN BAYI DI BPM PIPIN HERIYANTI YOGYAKARTA

2019 ◽  
Vol 7 (2) ◽  
pp. 143-148
Author(s):  
Dwi Yulinda
Keyword(s):  
Weight Loss ◽  
Birth Weight ◽  
Treatment Group ◽  
Breast Milk ◽  
Date Palm ◽  
Control Group ◽  
Milk Product ◽  
Milk Supply ◽  
Palm Fruit ◽  
Palm Fruits

Background: Galactogogues is one of pharmaticeutical agents to support the initiation, continuation or augmentatiton of breast milk product. Natural product of galactogogues contenst such as palm fruits. So many puerpural mother prefer using natural galactogogues to help incerase their milk supply is in observing successive measurment of the infant’s naked weight. Nearly all infants lose weight for the first two to four days after birth. Postnatal weight loss on regaining birth weight are cliical parameters for monitoring an infat feeding status in the first week. Objective: This study aimed to assess the effect of date palm fruits on postpartum to infant weight Methods: Research was conducted on maternal postpartum which is divided into two groups. They are the control group; and the treatment group which was given dates palm fruit. Infant weight was measured at 7 day after birth. The analytical method used is Student T-test. Results: Date Palm fruits increased infant weight which was significantly on firstweek increase in the treatment group compared to the control group at p <0.05. Conclusion: Date Palm fruits is one of the alternatives that can be done to prevent infant lose weight. Keywords: Date palm fruit, postpartum, infant weight

scholarly journals Breast Milk Supply of MicroRNA Associated with Leptin and Adiponectin Is Affected by Maternal Overweight/Obesity and Influences Infancy BMI

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2589 ◽  
Author(s):  
Rocío Zamanillo ◽  
Juana Sánchez ◽  
Francisca Serra ◽  
Andreu Palou
Keyword(s):  
Breast Milk ◽  
Target Genes ◽  
Maternal Obesity ◽  
Infant Growth ◽  
Normal Weight ◽  
Milk Supply ◽  
Milk Samples ◽  
Lactating Mothers ◽  
Maternal Overweight ◽  
Over Time

Breast milk constitutes a dietary source of leptin, adiponectin and microRNAs (miRNAs) for newborns. Expression of miRNAs previously associated with maternal obesity, leptin or adiponectin function were assessed and their impact on infant weight analyzed. Milk samples were collected (at month 1, 2, and 3) from a cohort of 59 healthy lactating mothers (38 normal-weight and 21 overweight/obese (BMI ≥ 25)), and infant growth was followed up to 2 years of age. Thirteen miRNAs, leptin and adiponectin were determined in milk. Leptin, adiponectin and miRNA showed a decrease over time of lactation in normal-weight mothers that was altered in overweight/obesity. Furthermore, negative correlations were observed in normal-weight mothers between the expression of miRNAs in milk and the concentration of leptin or adiponectin, but were absent in overweight/obesity. Moreover, miRNAs negatively correlated with infant BMI only in normal-weight mothers (miR-103, miR-17, miR-181a, miR-222, miR-let7c and miR-146b). Interestingly, target genes of milk miRNAs differently regulated in overweight/obesity could be related to neurodevelopmental processes. In conclusion, a set of miRNAs present in breast milk, in close conjunction with leptin and adiponectin, are natural bioactive compounds with the potential to modulate infant growth and brain development, an interplay that is disturbed in the case of maternal overweight/obesity.

scholarly journals The Role of Endorphin Stimulation, Oxytocin Massage and Suggestive Technique (SPEOS) in Improving Breast Milk Production among Breastfeeding Mother at Primary Health Center in Cimahi Tengah, West Java, Indonesia

2019 ◽  
Author(s):  
Hemi Hemi Fitriani ◽  
Ismafiaty . ◽  
Syifa Nadira
Keyword(s):  
Breast Milk ◽  
Milk Production ◽  
Health Research ◽  
Post Partum ◽  
Intervention Group ◽  
Health Science ◽  
Control Group ◽  
Milk Supply ◽  
Breast Milk Production ◽  
Primary Health

Inadequatemilksupplyduringthefirstfewdays’after delivery become concern from most of the women. Indonesia Health Research and Development Agency in 2010 stated that the failure of exclusive breastfeeding commonly caused by insufficient milk production. The intervention of SPEOS (EndorphinStimulation, Oxytocin Massage, and Suggestive Technique) methods are offered to post-partum mothers in increasing breast milk supply. This study aimed to identify the influence of SPEOS on breast milk supply among post-partum mothers at Primary Health Care in Cimahi Tengah Indonesia. Quasi-experimental research with non-equivalent control group design was conducted. A total of 20 postpartum mothers were involved in this studyby using accidental sampling technique. The data were taken from March to April 2018 through observation on the amount of breast milk by pumping in two times observation including before and after the SPEOS method applied. The data were analyzed by t-independent test. Ethical approval was obtained from Health Research and Ethics Committee of Institute of Health Science Jenderal Achmad Yani Cimahi No. 005/KEPK/II/2018. The result shows that the intervention group produces more breast milkasmuchas3,74cconthethirddaysoftheexperimentthanthecontrolgroup(2,04 cc).Bivariateanalysisshowspvalue0,001.Therefore,SPEOS methods gives significant influences on breast milk supply among post partum mothers. Conclusions SPEOS methods are effective in increasing low breast milk supply amongpost-partummothers.

scholarly journals Use of Domperidone to Increase Breast Milk Supply

2014 ◽  
Vol 30 (4) ◽  
pp. 498-499 ◽  
Author(s):  
Luke Grzeskowiak
Keyword(s):  
Breast Milk ◽  
Milk Supply

scholarly journals Parents’ views on factors that help or hinder breast milk supply in neonatal care units: systematic review

2013 ◽  
Vol 98 (6) ◽  
pp. F511-F517 ◽  
Author(s):  
Elisabete Alves ◽  
Carina Rodrigues ◽  
Sílvia Fraga ◽  
Henrique Barros ◽  
Susana Silva
Keyword(s):  
Systematic Review ◽  
Breast Milk ◽  
Neonatal Care ◽  
Milk Supply

Traditional methods used by mothers living in different regions of Turkey for increasıng breast milk supply and weaning

2019 ◽  
Vol 2 ◽  
pp. 13-20
Author(s):  
Buyuk E. Tural ◽  
E. Sak Kilic ◽  
A. Karakurt
Keyword(s):  
Breast Milk ◽  
Regional Differences ◽  
Eastern Region ◽  
Milk Supply ◽  
Traditional Methods ◽  
Cross Sectional ◽  
Tomato Paste ◽  
Questionnaire Form ◽  
Economic Regions ◽  
Different Levels

<b>Introduction:</b> It is a known fact that traditional practices mothers use in increasing breast milk supply and weaning differ in different parts of countries and even among communities sharing the same city. This study was conducted to find out the use of herbal tea and some foods to increase breast milk, the traditional methods used for weaning and the factors influencing these. <br><b>Materials and methods:</b> This study is descriptive and cross-sectional. Three cities in Turkey with different levels of development in terms of geographical and socio economic regions were chosen. The data of the study were collected through a questionnaire form developed by the researchers. <br><b>Results:</b> It was found that the mothers who received breast milk increasing training the most were in eastern region, while mothers in western region fed their babies with formula since they thought their milk was not enough and this result was found to be statistically significant (p<0.05). In our study, it was found that 42.1% of the mothers resorted to some plants and foods to increase breast milk. When the mothers were asked about how they weaned their babies, it was found that 38.2% pasted things like hair and wool or put tomato paste on the breast, 26.9% applied bitter food on the nipple while 27.7% stated that the babies stopped breastfeeding spontaneously. <br><b>Conclusion:</b> It was found that mothers resorted to traditional methods to increase breast milk and to wean and that there were regional differences.

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