scholarly journals Metabolic and psychological effects of increased consumption of less-processed foods in daily diets

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
E Nano ◽  
G Isoardo ◽  
G Migliaretti ◽  
S Ciullo

Abstract Aim This study evaluated whether the consumption of locally produced food without additives might have a positive effect on known risk factors for non-communicable diseases (NCDs) such as hypertension, and levels of fasting glucose and visceral adipose tissue (VAT). Attention was focused on various types of cheese, sausages, fresh pasta, pastries, biscuits and chocolate without additives to make them palatable and durable for transport. Methods Healthy volunteers were randomized to purchase the foods under study from either local producers not using additives (group 1) or supermarkets (group 2). At baseline and after 6 months, both groups underwent evaluation for weight, blood pressure, VAT, serum sodium, potassium, fasting glucose, insulin, C-peptide and creatinine levels, and also the State-Trait Anxiety Inventory (STAI) and Beck Depression Inventory (BDI-II) by examiners blinded to group allocation. At baseline, the state part of the STAI and Wechsler Adult Intelligence Scale IV were also performed, and body mass index, HOMA index and estimated glomerular filtration rate calculated. Results Data for 159 subjects (89 in group 1, 70 in group 2) were analyzed. Baseline evaluations did not differ between groups. At 6 months, HOMA scores and fasting glucose levels were lower in group 1 than in group 2 (P < 0.01). Also, in group 1, VAT (P = 0.006), systolic blood pressure (P = 0.001) and BDIII score (P = 0.0005) were decreased, whereas serum fasting glucose (P = 0.04) and C-peptide (P = 0.03) levels, and diastolic blood pressure (P = 0.02), were increased in group 2. Conclusions Consumption of the locally produced food under study improved some of the major risk factors for NCDs after 6 months. Key messages We evaluate whether the consumption of locally produced food without additives might have a positive effect on known risk factors for non-communicable diseases (NCDs) and psychological factors. Consumption of the locally produced food under study improved some of the major risk factors for NCDs and psychological test scores after 6 months.

2013 ◽  
Vol 7 ◽  
pp. CMC.S12654 ◽  
Author(s):  
J. Meikle ◽  
A. Al-Sarraf ◽  
M. Li ◽  
K. Grierson ◽  
J. Frohlich

Objective To assess the effects of exercise on resting heart rate (RHR), weight, lipid profile, and blood pressure. We hypothesized that the participants who increased their physical activity would show improvement in their cardiovascular risk factors compared to those who did not. Design Retrospective chart review over the mean duration of 4.9 years of follow-up. Setting Healthy Heart Program Prevention Clinic at St. Paul's Hospital, Vancouver, British Columbia, Canada. Participants We reviewed 300 charts of patients randomly selected from those who attended the Prevention Clinic between 1984 and 2009. 248 (82.7%) patients were referred for primary prevention and 52 (17.3%) for secondary prevention. Primary and secondary outcome measures Weight, RHR, lipid profile, and blood pressure were recorded at the initial and last visit. Results During a mean of 4.9 years of follow-up, 55% of participants improved their exercise. The mean decrease in the RHR for these patients (group 1) was 5.9 beats per minute (bpm) versus the mean increase of 0.3 bpm for the “no change” group (group 2) ( P < 0.01). The mean net weight increase in group 1 was 0.06 kg/year versus 0.25 kg/year in group 2. Because of medications, all patients had a significant improvement in their lipid profiles. Furthermore, there was a statistically significant greater reduction in Framingham Risk Score (FRS) in group 1 versus group 2 (11.8% versus 15.1%, P < 0.01). Conclusion Participation in the program significantly reduces modifiable risk factors for cardiovascular disease. Improved exercise regimen results in lower RHR and greater reduction in FRS. However, even in a Prevention Program, despite strong advocacy of the importance of exercise, a significant percentage of participants does not improve their exercise habits.


2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Giuseppina Piazzolla ◽  
Mafalda Candigliota ◽  
Margherita Fanelli ◽  
Anna Castrovilli ◽  
Elsa Berardi ◽  
...  

Abstract Background Metabolic syndrome (MetS) is a clinical condition potentially promoting the development of atherosclerotic disease. To date, the clinical impact of elevated serum homocysteine (Hcy) levels in MetS is still under discussion. The aim of this cross sectional study was to evaluate the relationship between MetS and hyperhomocysteinemia and the potential role of Hcy in the pathogenesis of atherosclerotic complications of MetS. Methods We recruited 300 outpatients with MetS. All patients underwent a medical history collection, physical examination, blood sampling and carotid ultrasound echo-color Doppler. According to Hcy levels, MetS patients were divided into two groups: “normal” (< 10.7 μmol/l; n = 140, group 1) and “high” Hcy (≥ 10.7 μmol/l; n = 160, group 2). Comparisons between groups were made by Student’s t-test or Chi-square test. The effects of potential covariates on group differences were evaluated by general linear models. The relationships between continuous variables were assessed by simple or multiple correlation and by linear regression. Multiple regression models were built to evaluate the effects of Hcy, together with other potential risk factors, on carotid atherosclerosis. Results Patients with high Hcy were predominantly male and slightly older than group 1 patients. Smokers and non-smokers exhibited similar Hcy levels, nor was a statistical relationship between pack-years and Hcy observed. Group 2 showed lower levels of folic acid, vitamin D, high density lipoprotein (HDL)-cholesterol and glomerular filtration rate (e-GFR) than group 1, but higher levels of C-peptide, uric acid and triglycerides. In all patients, Hcy was positively correlated with C-peptide and uric acid and negatively with folic acid and e-GFR. Intima-media thickness (IMT) and carotid stenosis degree were significantly higher in patients with high Hcy and a positive relationship between Hcy and both IMT and carotid stenosis was detected in all patients. Finally, Hcy atherogenic effects were independent of other well-known atherosclerosis risk factors. Conclusions Our results highlight a link between MetS and hyperhomocysteinemia and a direct effect of Hcy on atherogenic process during MetS. Early correction of folic acid levels may contribute to prevent cardiovascular complications in MetS patients.


2018 ◽  
Vol 47 (7) ◽  
pp. 705-712
Author(s):  
Sidsel Graff-Iversen ◽  
Inger Ariansen ◽  
Øyvind Næss ◽  
Randi M. Selmer ◽  
Bjørn Heine Strand

Background: The absolute educational differences in the mortality of Norwegian women and men increased during 1960–2000 and thereafter levelled off in men, but continued to widen in women. Which of the risk factors for non-communicable diseases (NCDs) might explain these trends? Aim: The aim of this study was to investigate trends in gender-specific, absolute educational differences in established risk factors during 1974–2002. Methods: We used cross-sectional data from 40–45-year-old women and men who participated in one of three health surveys in two counties, from the years 1974–1978, 1985–1988 and 2001–2002. To account for increasing educational attainment through the period we used a regression-based index of inequality (Slope Index of Inequality) to assess the educational gradients over time. Results: From 1974 to 2002, the mean levels of serum total cholesterol and blood pressure decreased and body mass index (BMI) increased in all subgroups by education in both sexes. In men, the educational gradient tended to diminish toward the null for serum total cholesterol and narrowed for systolic blood pressure, but increased for BMI. In women, the educational gradient increased to the double for smoking and increased for triglycerides. Conclusions: In two Norwegian counties, the NCD risk factors showed dynamic patterns during 1974–2002. For blood pressure and serum total cholesterol, the levels showed consistent beneficial changes in all educational subgroups, with a narrowing tendency for educational gradients in men. In women, the educational gradient for smoking increased markedly. Knowledge on midlife trends in the educational gradients of risk factors may help to explain recent and future NCD mortality.


Author(s):  
Sumit Audichya ◽  
Pavithra H. ◽  
Harikrishnan V. ◽  
Kibballi Madhukeshwar Akshaya

Background: Non communicable diseases (NCDs) are on the rise among workers in various occupations resulting in morbidity and mortality. This study was conducted to assess the various risk factors and associated socio-demographic factors among the security and transport personnel working in a health sciences university in Mangaluru.Methods: It was a cross-sectional study conducted among all the security and transport personnel. Questionnaire based on WHO-STEPS approach was used. Blood pressure (BP) measurements were recorded.Results: Total 167 study participants were enrolled; 57.5% were security and rest were transport personnel. Physical activity was perceived as light by 63.5% participants. Current smokers constituted to 26% and 33.5% consumed alcohol in past 12 months. Eighteen percent of them top salted their food. Among participants who were apparently healthy, 12.5% and 23.4% had raised systolic and diastolic BP. Associations between the areas of residence (p=0.004) and type of occupation (p<0.001) were found to be significant.Conclusions: Prevalence of risk factors of NCDs was high among study participants. Only few study subjects were physically active and majority of them felt that their routine work provided them with light physical activity. Around one third of the participants consumed tobacco and alcohol. Around 1/4th of the study participants who were not known hypertensive, were found with increased levels of blood pressure.


2020 ◽  
Author(s):  
Samwel Maina Gatimu ◽  
Thomas Wiswa John

Abstract IntroductionOne in four Kenyans have raised blood pressure. Despite this high prevalence of hypertension and known association between socioeconomic status and hypertension, there is a paucity of evidence on inequality in raised blood pressure in Kenya. Hence, we quantified the socioeconomic inequality in hypertension in Kenya and decomposed the determinants contributing to such inequality.MethodsWe used data from the 2015 Kenya STEP wise survey for non-communicable diseases risk factors. We included 4,398 respondents aged 18–69 years. We estimated the socioeconomic inequality using the concentration index (C) and decomposed the C using Wag staff decomposition analysis.ResultsThe overall concentration index of hypertension in Kenya was − 0.08 (95% CI: −0.14, − 0.02; p = 0.007), showing socioeconomic inequalities in hypertension disfavouring the poor population. Half (52.8%) of the pro-rich inequalities in hypertension was explained by body mass index (52.8%) while 21.1% by socioeconomic factors (paid employment (9.3%), education (7.7%) and poorest wealth quintile (4.1%)) and 17.6% by demographic factors (female gender (11.8%), age (5.2%) and marital status (0.6%)). Regional differences explained 8.1% of the estimated inequality with the Central region alone explaining 6.9% of the observed inequality. Our model explained 98.3% of the estimated socioeconomic inequality in hypertension in Kenya with a small non-explained part of the inequality (− 0.001).ConclusionThe present study shows substantial socioeconomic inequalities in hypertension in Kenya, mainly explained by metabolic risk factors (body mass index), individual health behaviours, and socioeconomic factors. Kenya needs gender- and equity-focused interventions to curb the rising burden of hypertension and inequalities in hypertension.


2020 ◽  
Vol 4 (2) ◽  
pp. 16
Author(s):  
I Putu Sudayasa ◽  
Muhammad Fathur Rahman ◽  
Amiruddin Eso ◽  
Jamaluddin Jamaluddin ◽  
Parawansah Parawansah ◽  
...  

ABSTRAKPenyakit tidak menular (PTM) merupakan penyakit yang tidak ditularkan dan tidak ditransmisikan kepada orang lain dengan bentuk kontak apapun, menyebabkan kematian dan membunuh sekitar 35 juta manusia setiap tahunnya, atau 60% dari seluruh kematian secara global, dengan 80% pervalensi pada negara berkembang. Penyakit tidak menular, khususnya penyakit kardiovaskuler, kanker, penyakit pernapasan kronis, dan diabetes merupakan ancaman utama bagi kesehatan dan perkembangan manusia saat ini. Tujuan pengabdian masyarakat yang terintegrasi kuliah kerja nyata (KKN) Tematik, untuk mendeteksi faktor risiko penyakit tidak menular, pada masyarakat Kecamatan Sampara, Kabupaten Konawe. Metode kegiatan berupa penyuluhan kesehatan, pemeriksaan tekanan darah, kadar kolesterol, gula darah sewaktu dan asam urat. Telah dilakukan skrining dan deteksi dini fator risiko penyakit tidak menular terhadap 67 orang responden, meliputi 14 laki–laki dan 53 perempuan. Pada hasil pemeriksaan tekanan darah, didapatkan jumlah yang mengalami hipertensi 28,35 %, normotensi 67,16, dan hipotensi 4,47 %. Pada pemeriksaan Kolesterol Total, didapatkan  kolesterol dalam batas normal 2,38 % dan tinggi 37,31 %.  Hasil pemeriksaan gula darah sewaktu (GDS), didapatkan kadar GDS dalam batas normal 85,07 % dan kadar GDS tinggi 14,92 %. Pada pemeriksaan Asam Urat didapatkan dalam batas normal adalah 91,04 % dan tinggi 8,95 %.Kata kunci: Faktor Risiko; Penyakit Tidak Menular Early Detection of Non-communicable Disease Risk Factors in Andepali Village Community, Sampara District, Konawe RegencyABSTRACTNon-communicable disease (PTM) is a disease that is not transmitted and is not transmitted to others by any form of contact, causing death and killing around 35 million people each year, or 60% of all deaths globally, with 80% prevalence in developing countries. PTM, especially cardiovascular disease, cancer, chronic respiratory diseases, and diabetes are the main threats to human health and development today. The purpose of integrated community service is the Thematic Real Work Study (KKN), to detect risk factors for non-communicable diseases, in the community of Sampara District, Konawe Regency. The method of activity in the form of health education, blood pressure, cholesterol levels, blood sugar and uric acid. Screening and early detection of risk factors for non-communicable diseases have been carried out on 67 respondents, including 14 men and 53 women. On the results of blood pressure examination, it was found that the amount of hypertension was 28.35%, normotension 67.16% and hypotension 4.47%. In the examination of Total Cholesterol, cholesterol was found to be within the normal limit of 2.38% and 37.31% high. Examination results of Blood Sugar (GDS), obtained levels of GDS in the normal range of 85.07% and high GDS levels of 14.92%. In the examination of Gout found in the normal range is 91.04% and high 8.95%.Keywords: gout; blood sugar; cholesterol; non-communicable diseases; blood pressure 


Author(s):  
Naresh Kumar Panneerselvam ◽  
Preethi K. Suresh ◽  
Dhilip Ravindran ◽  
Ezhil Ratnakumari Manoharan

Abstract Objectives A healthy lifestyle is one, where the individual adapts it aiming at prevention from ailments. Unhealthy lifestyle is a behavioral risk factor for non-communicable diseases (NCDs). Arogya Raksha Panchatantra (five principles of healthy living), is a Naturopathy and Yoga lifestyle practice proposed by an eminent Indian Naturopath Dr. B. Venkat Rao, observed to modify the behavioral risk factors. The main objective of this study is to observe the changes in Hematological parameters and Anthropometric measures by practicing this Naturopathic lifestyle. Methods The study adapted one group Pretest – Posttest quasi experimental design, with a total of nine healthy student volunteers between age group 18–20 years. Hematological parameters such as total blood cells count, hemoglobin concentration, MCV, MCH, PCV, and anthropometric measurements such as weight, body circumferences (waist, hip) and changes in blood pressure were measured at baseline and after practice at 25th day. Results There was a statistically significant difference observed in weight, waist and hip circumference, hematological indices except with MCV and MCH, and blood pressure (p<0.05), with no significant changes in waist-hip ratio and blood counts. Conclusions The findings of the study indicate that adapting Naturopathy and Yoga lifestyle based on proposed lifestyle practices may be beneficial in reducing the risk factors for non-communicable diseases. The study does not attribute the effects observed to any particular lifestyle practiced in this study; rather it is combination of healthy practices as observed in the study and it needs further longitudinal observations whether the beneficial effect of Naturopathy lifestyle practices is sustained for longer period of time.


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