scholarly journals Depressive Symptoms Mediate the Influence of Fibromyalgia Status on Physical Performance and BMI in Aging Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 858-858
Author(s):  
Dylan Serpas ◽  
Laura Zettel-Watson ◽  
Barbara Cherry
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Physical Performance ◽  
Performance Measure ◽  
Walk Test ◽  
Middle Aged ◽  
Chair Stand ◽  
Aging Adults ◽  
6 Minute Walk Test ◽  
Minute Walk

Abstract Fibromyalgia is a chronic pain condition that is frequently accompanied by comorbid conditions, including depression. Depression is associated with reduced physical functioning and health disproportionately affecting middle-aged and older adults with fibromyalgia. This study examined depressive symptoms as a mechanism through which FM status is associated with BMI and physical performance among adults in mid-to-late-life. Participants included 250 community-dwelling middle-aged and older adults (82% female) with (59%) or without (41%) fibromyalgia (M age = 64.44, SD = 9.16). Depressive symptoms were measured using the Beck Depression Inventory-II, BMI was objectively assessed, and physical performance was measured using the Fullerton Advanced Balance scale, 6-Minute Walk Test, 30-Second Chair Stand, and 8-Foot Up and Go Test. Physical performance measure analyses were adjusted for age. Asymptotic mediation analyses revealed that fibromyalgia status was indirectly associated with higher BMI (95% CI [.18, 16.74]), and poorer performance in the Fullerton Advanced Balance (CI [-2.93, -1.24]), 6-Minute Walk Test (CI [-73.75, -35.35]), 30-Second Chair Stand (CI [-2.45, -1.16]), and 8-Foot Up and Go test (CI [.35, .92]) via depressive symptoms. Participants with fibromyalgia reported greater depressive symptoms which was subsequently associated with greater BMI and reduced physical performance. Findings support depressive symptoms as one factor through which fibromyalgia status is associated with higher obesity risk and reduced physical function in middle-aged and older adults with fibromyalgia. This study supports fibromyalgia status as a critical consideration when evaluating the health and disability risk of aging adults.

Pain intensity and physical performance among individuals with fibromyalgia in mid-to-late life: The influence of depressive symptoms

2021 ◽  
pp. 135910532110092
Author(s):  
Dylan G Serpas ◽  
Laura Zettel-Watson ◽  
Barbara J Cherry
Keyword(s):  
Depressive Symptoms ◽  
Pain Intensity ◽  
Physical Performance ◽  
Walk Test ◽  
Mediation Analyses ◽  
Mediating Role ◽  
6 Minute Walk Test ◽  
The Relationship ◽  
Minute Walk

This study investigated the mediating role of depressive symptoms among 147 middle-aged and older adults with FM in the relationship between pain intensity and 4 objective measures of physical performance: Fullerton Advanced Balance scale (FAB), 6-Minute Walk Test (6MWT), 30-Second Chair Stand (30SCS), and 8-Foot Up and Go Test (8FUPGT). Asymptotic mediation analyses revealed that depressive symptoms fully mediated the relationship between pain intensity and FAB (95% CI [−0.40, −0.10]) and 8FUPGT (CI [0.02, 0.11]) and partially mediated the relationship to 6MWT (CI [−9.15, −2.20]) and 30SCS (CI [−0.29, −0.06]). Findings support the evaluation of co-morbid depression in FM.

scholarly journals Reliability and Responsiveness of Two Physical Performance Measures Examined in the Context of a Functional Training Intervention

2000 ◽  
Vol 80 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Mary B King ◽  
James O Judge ◽  
Robert Whipple ◽  
Leslie Wolfson
Keyword(s):  
Physical Performance ◽  
Interrater Reliability ◽  
Intraclass Correlation ◽  
Intervention Group ◽  
Training Intervention ◽  
Control Group ◽  
Walk Test ◽  
Test Retest Reliability ◽  
6 Minute Walk Test ◽  
Minute Walk

Abstract Background and Purpose. The reliability and responsiveness of 2 physical performance measures were assessed in this nonrandomized, controlled pilot exercise intervention. Subjects. Forty-five older individuals with mobility impairment (mean age=77.9 years, SD=5.9, range=70–92) were sequentially assigned to participate in an exercise program (intervention group) or to a control group. Methods. The intervention group performed exercise 3 times a week for 12 weeks that targeted muscle force, endurance, balance, and flexibility. Outcome measures were the 8-item Physical Performance Test (PPT-8) and the 6-minute walk test. Test-retest reliability and responsiveness indexes were determined for both tests; interrater reliability was measured for the PPT-8. Results. The intraclass correlation coefficient for interrater reliability for the PPT-8 was .96. Intraclass correlation coefficients for test-retest reliability were .88 for the PPT-8 and .93 for the 6-minute walk test. The intervention group improved 2.4 points and the control group improved 0.7 point on the PPT-8, as compared with baseline measurements. There was no change in 6-minute walk test distance in the intervention group when compared with the control group. The responsiveness index was .8 for the PPT-8 and .6 for the 6-minute walk test. Conclusion and Discussion. Measurements for both the PPT-8 and the 6-minute walk test appeared to be highly reliable. The PPT-8 was more responsive than the 6-minute walk test to change in performance expected with this functional training intervention.

The Utility of the 6-Minute Walk Test as a Measure of Frailty in Older Adults with Heart Failure

2008 ◽  
Vol 17 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Rebecca S. Boxer ◽  
Zhu Wang ◽  
Stephen J. Walsh ◽  
David Hager ◽  
Anne M. Kenny
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Walk Test ◽  
6 Minute Walk Test ◽  
Minute Walk

scholarly journals Fall risk classification for people with lower extremity amputations using random forests and smartphone sensor features from a 6-minute walk test

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0247574
Author(s):  
Kyle J. F. Daines ◽  
Natalie Baddour ◽  
Helena Burger ◽  
Andrej Bavec ◽  
Edward D. Lemaire
Keyword(s):  
Older Adults ◽  
Feature Selection ◽  
Lower Limb ◽  
Fall Risk ◽  
Random Forest Classifier ◽  
Risk Classification ◽  
Walk Test ◽  
Correlation Based Feature Selection ◽  
6 Minute Walk Test ◽  
Minute Walk

Fall-risk classification is a challenging but necessary task to enable the recommendation of preventative programs for individuals identified at risk for falling. Existing research has primarily focused on older adults, with no predictive fall-risk models for lower limb amputees, despite their greater likelihood of fall-risk than older adults. In this study, 89 amputees with varying degrees of lower limb amputation were asked if they had fallen in the past 6 months. Those who reported at least one fall were considered a fall risk. Each participant performed a 6 minute walk test (6MWT) with an Android smartphone placed in a holder located on the back of the pelvis. A fall-risk classification method was developed using data from sensors within the smartphone. The Ottawa Hospital Rehabilitation Center Walk Test app captured accelerometer and gyroscope data during the 6MWT. From this data, foot strikes were identified, and 248 features were extracted from the collection of steps. Steps were segmented into turn and straight walking, and four different data sets were created: turn steps, straightaway steps, straightaway and turn steps, and all steps. From these, three feature selection techniques (correlation-based feature selection, relief F, and extra trees classifier ensemble) were used to eliminate redundant or ineffective features. Each feature subset was tested with a random forest classifier and optimized for the best number of trees. The best model used turn data, with three features selected by Correlation-based feature selection (CFS), and used 500 trees in a random forest classifier. The resulting metrics were 81.3% accuracy, 57.2% sensitivity, 94.9% specificity, a Matthews correlation coefficient of 0.587, and an F1 score of 0.83. Since the outcomes are comparable to metrics achieved by existing clinical tests, the classifier may be viable for use in clinical practice.

scholarly journals Factors associated with the 6-minute walk test in nursing home residents and community-dwelling older adults

2015 ◽  
Vol 27 (11) ◽  
pp. 3571-3578 ◽  
Author(s):  
Vicent Benavent-Caballer ◽  
Juan Francisco Lisón ◽  
Pedro Rosado-Calatayud ◽  
Juan José Amer-Cuenca ◽  
Eva Segura-Orti
Keyword(s):  
Older Adults ◽  
Nursing Home ◽  
Nursing Home Residents ◽  
Community Dwelling ◽  
Walk Test ◽  
Factors Associated ◽  
6 Minute Walk Test ◽  
Community Dwelling Older Adults ◽  
Minute Walk

scholarly journals Objectively Measured Physical Activity in Asymptomatic Middle-Aged Men Is Associated With Routine Blood-Based Biomarkers

2019 ◽  
Vol 74 (Supplement_1) ◽  
pp. S32-S37 ◽  
Author(s):  
Karol M Pencina ◽  
Zhuoying Li ◽  
Monty Montano
Keyword(s):  
Physical Activity ◽  
T Cell ◽  
Gait Speed ◽  
Sex Hormone Binding Globulin ◽  
Walk Test ◽  
Middle Aged ◽  
Cross Sectional ◽  
Increased Risk ◽  
6 Minute Walk Test ◽  
Minute Walk

Abstract Background The use of circulating clinically routine biomarkers and volitional physical activity using wristband accelerometry in preclinical middle-aged adults may provide sensitive measures of physical function and predict sooner the onset of age- and HIV-related physical decline. Methods Nested cross-sectional cohort study of adult men 50–65 years old with HIV infection on potent antiretroviral therapy and uninfected control participants within the Boston metropolitan area. Gait speed derived from wristband accelerometry, gait speed derived from a standardized 6-minute walk test, cellular immune biomarker levels (CD4 T cell, CD8 T cell), and serum anabolic biomarker levels (total and free testosterone, and sex-hormone-binding globulin) were measured. Results Of the five measured biomarkers, four were significantly associated with volitional gait speed based on accelerometry, whereas only one was associated with gait speed based on the 6-minute walk test collected in a laboratory environment. Conclusion Levels of selected immune and anabolic biomarkers were associated with volitional physical activity in middle-aged individuals. Digital and circulating biomarkers may be useful in future studies designed to identify presymptomatic individuals at increased risk for age- and HIV-associated functional decline.

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