Aetiology

2012 ◽  
pp. 83-114
Author(s):  
Philip Cowen ◽  
Paul Harrison ◽  
Tom Burns
Keyword(s):  
Mental Disorders ◽  
Clinical Studies ◽  
Clinical Work ◽  
Community Surveys ◽  
Scientific Disciplines ◽  
Laboratory Investigations ◽  
The Individual

Psychiatrists are concerned with aetiology in two ways. First, in everyday clinical work they try to discover the causes of the mental disorders presented by individual patients. Secondly, in seeking a wider understanding of psychiatry they are interested in aetiological evidence obtained from clinical studies, community surveys, or laboratory investigations. Correspondingly, the first part of chapter 5 deals with some general issues relating to aetiology in the assessment of the individual patient, while the second part deals with the various scientific disciplines that have been applied to the study of aetiology.

scholarly journals Deployment-Related Traumatic Events and Suicidal Behaviours in a Nationally Representative Sample of Canadian Armed Forces Personnel

2017 ◽  
Vol 62 (11) ◽  
pp. 795-804 ◽  
Author(s):  
Jitender Sareen ◽  
Tracie O. Afifi ◽  
Tamara Taillieu ◽  
Kristene Cheung ◽  
Sarah Turner ◽  
...  
Keyword(s):  
Child Abuse ◽  
Mental Disorders ◽  
Suicidal Behaviour ◽  
Traumatic Events ◽  
Armed Forces ◽  
Canadian Armed Forces ◽  
Increased Risk ◽  
Nationally Representative ◽  
The Individual ◽  
Suicidal Plans

Objective: Worldwide, there has been substantial controversy with respect to whether military deployment is a risk factor for suicidal behaviour. The present study examined the relationship between lifetime exposure to deployment and deployment-related traumatic events (DRTEs) and past-year suicidal ideation (SI), suicidal plans (SP), and suicidal attempts (SA). Method: Data were analysed from the 2013 Canadian Forces Mental Health Survey (8161 respondents; response rate, 79.8%; aged 18-60 years). A total of 12 individual items assessed exposure to DRTEs (e.g., combat, witnessing human atrocities, feeling responsible for the death of Canadian or ally personnel, knowing someone who was injured or killed). We examined each individual DRTE type as well as the number of types of DRTEs in relation to suicidal behaviour. Results: Lifetime deployment was not significantly associated with suicidal behaviour. In models adjusted for sociodemographic variables, most of the individual DRTE items and the DRTE count variable were significantly associated with suicidal behaviours (adjusted odds ratio ranged between 1.10 and 5.32). When further adjusting for child abuse exposure, these associations were minimally attenuated, and some became nonsignificant. In models adjusting for mental disorders and child abuse, most DRTEs and number of types of DRTEs became nonsignificant in relation to SI, SP, and SA. Conclusions: Active military personnel exposed to increasing number of DRTEs are at increased risk for SI, SP, and SA. However, most of the association between DRTEs and suicidal behaviour is accounted for by child abuse exposure and mental disorders.

scholarly journals Actions of the nurse to the patient with a mental disorder

2021 ◽  
Vol 10 (1) ◽  
pp. e15510110385
Author(s):  
Aline de Sousa Rocha ◽  
Benedita Maryjose Gleyk Gomes ◽  
Roberta Sousa Meneses ◽  
Marcos Antonio Silva Batista ◽  
Rosane Cristina Mendes Gonçalves ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Mental Disorder ◽  
Nursing Care ◽  
Temporal Analysis ◽  
Social Reintegration ◽  
The Family ◽  
The World ◽  
The Individual ◽  
Provision Of Care ◽  
The Relationship

The psychiatric reform that took place in Brazil carries characteristics of other movements that occurred in other parts of the world. The idea common to all movements is the struggle for the rights of the individual in mental suffering, seeking mainly the rupture of the mental model. These changes led to several transformations in the care scenario, for all professions directly linked to the patient. Nursing in turn has experienced and experiences significant changes in the provision of care. The aim of this study is to talk about nursing care for patients affected by mental disorder, making a temporal analysis of how this care occurred and how it presents itself in the current mental health conjuncture. The methodology is of the literature review type, which occurred through research in the databases BIREME, Lilacs, Scielo, BDENF and VHL. For this, the descriptors: nursing care for people with disorders were selected; nursing care for patients with mental disorders. In view of the results, it was evidenced that nurses are an important part of caring for patients with mental disorders, noting that these make up a multidisciplinary team and highlighting that care goes far beyond just caring for the patient, but that it consists mainly in the relationship with the patient's family, in bonding, in the work that aims at social reintegration and often also the family reinsertion of the individual. Profession that needs to undergo constant updates, but has experienced numerous transformations throughout this period of Reformation.

scholarly journals From the Clinic to the Laboratory, and Back Again: Investigations on Cannabinoids and Endocannabinoid System Modulators for Treating Schizophrenia

2021 ◽  
Vol 12 ◽  
Author(s):  
Kurt Leroy Hoffman
Keyword(s):  
Animal Models ◽  
Outcome Measures ◽  
Clinical Studies ◽  
Cannabinoid Receptors ◽  
Endocannabinoid System ◽  
Clinical Work ◽  
Clinical Results ◽  
Cognitive Outcome ◽  
Experimental Drugs ◽  
First Results

The present mini-review focuses on animal models of schizophrenia that have explored the effects of cannabidiol (CBD; a non-psychoactive component of cannabis) or the pharmacological manipulation of the endocannabinoid system on behavioral and cognitive outcome measures. First, results of some relevant clinical studies in this area are summarized, and then pre-clinical work on animal models of schizophrenia based on NMDA receptor antagonism or neurodevelopmental manipulations are discussed. A brief overview is given of the theoretical framework on which these models are based, along with a concise summary of results that have been obtained. Clinical results using CBD for schizophrenia seem promising and its effects in animal models of schizophrenia support its potential as a useful pharmacotherapy. Animal models have been paramount for elucidating the actions of CBD and the function of the endocannabinoid system and for identifying novel pharmacological targets, such as cannabinoid receptors and anandamide. However, more attention needs to be placed on defining and applying independent variables and outcome measures that are comparable between pre-clinical and clinical studies. The objective of this review is, on the one hand, to emphasize the potential of such models to predict clinical response to experimental drugs, and on the other hand, to highlight areas in which research on such models could be improved.

scholarly journals Effects of Happiness on Mental Health

2015 ◽  
Vol 2 (3) ◽  
Author(s):  
Dr. Gopal Chandra Mahakud ◽  
Ritika Yadav
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
Social Situation ◽  
Psychological Problem ◽  
Health Conditions ◽  
Positive Attitudes ◽  
Psychic Disorders ◽  
As Stress ◽  
The Individual

The concept of mental health comprised to the health conditions of people without suffering any mental or psychological problem such as stress, depression, anxiety and other form of psychic disorders. In this regard it can be said that no one is free from and psychological, psycho-physical and psycho-social disorders from which we can derive that no one mentally healthy. But the concept of mental health defined free from the disorders those are prolonged and panic in nature. As the concept of mental health is subjective in nature, it varies from person to person. Besides free from the disorders, a person should pose some of the other positive characteristics to deal with the society effectively. Marry (1958) stated that, a person can be considered mentally healthy with the following characteristics such as (a) Positive attitudes toward himself/herself; (b) Realization of own potentialities through action; (c); Unification of in personality; (d) Degree of independence of social influences; (e) observations of the world around; and (f) Positive adapts to everyday life. Briefly, it can be said that positive mental health of the person make able to an individual to stand on his own two feet without making undue demands or impositions of others. In this regard the role of happiness in day to day life can make the individual more skilled to fight with different mental disorders. The present article is intended to find out the effects of happiness in day to day life in a social situation to deal with different mental disorders to make the individual mentally healthy and prosperous in life.

Psychotherapy

2019 ◽  
pp. 881-930
Author(s):  
David Semple ◽  
Roger Smyth
Keyword(s):  
Mental Disorders ◽  
Behavioural Therapy ◽  
Object Relations Theory ◽  
Behaviour Therapy ◽  
Cognitive Behavioural ◽  
History Of ◽  
Behavioural Therapies ◽  
The Individual ◽  
Background Context ◽  
Selection Of

This chapter covers the psychotherapies, a collection of treatments for mental disorders which employ language and communication as a means of producing change. It covers assessment and selection of an appropriate method for the individual patient, a history of Freud and other pioneers of psychotherapy to provide a background context, before examining different types of therapy. Briefly explaining the theory of psychotherapy, the phases of psychosexual development, and the object relations theory, it goes into detail on behavioural therapies such as cognitive behavioural therapy, interpersonal psychotherapy, dialectical behaviour therapy, and solution therapy. Counselling methods are described to aid the reader in developing their skills.

Coparenting, Parenting, and Child-Focused Family Interventions

2016 ◽  
pp. 222-242
Author(s):  
Matthew J. Sullivan ◽  
Robin M. Deutsch ◽  
Peggie Ward
Keyword(s):  
Clinical Work ◽  
Family Interventions ◽  
Final Session ◽  
The Family ◽  
The Individual ◽  
Parent Child

This chapter describes the clinical work with individual families during the Overcoming Barriers camp program. Though the practical goal is to restore parent-child contact and relationships in a gradual progressive between rejected parents and their children, the focus of these interventions is on the individual and relationship issues within the family that entrench the resistance or refusal dynamics. The chapter addresses the goals, objectives, and specific techniques that make up the clinical work with the coparents, the favored parent and child, the rejected parent and child, and the whole family. Also described is the progression of this work from intake through the final session. The process culminates with the documentation of any agreements that have been reached and with the parents’ committing to a specific aftercare plan.

scholarly journals Tavola Rotonda su: “Fattori prognostici e markers nel carcinoma della vescica”. Aspetti generali e introduttivi: Round Table on: “Prognostic factors and markers in bladder carcinoma”. General and introductory aspects

1995 ◽  
Vol 62 (2) ◽  
pp. 163-167
Author(s):  
G. Mobilio
Keyword(s):  
Prognostic Factors ◽  
Bladder Carcinoma ◽  
Predictive Value ◽  
Clinical Studies ◽  
Specific Treatment ◽  
Immunological Response ◽  
Round Table ◽  
End Points ◽  
The Individual ◽  
Bladder Tumours

Bladder tumours are generally grouped as superficial or invasive because of their different therapeutical regimens. Superficial tumours still cause uncertainties in choosing the best treatment due to their heterogeneity and different behaviour. In the prevision of these tumours it is important to consider all the factors that could influence the prognosis: tumoral characteristics, grading and staging mistakes, effects of the therapy and immunological response. Moreover it is important for clinical studies to have appropriate end points. Prognostic factors and markers with high predictive value can allow specific treatment for the individual cases to be planned.

scholarly journals T153. THE ECONOMIC BURDEN OF MENTAL DISORDERS: A SYSTEMATIC REVIEW

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S289-S289
Author(s):  
Maria Christensen ◽  
Carmen Lim ◽  
Sukanta Saha ◽  
Danielle Cannon ◽  
Finley Presley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Economic Burden ◽  
Economic Cost ◽  
Production Loss ◽  
Comprehensive Overview ◽  
Loss Method ◽  
The Individual ◽  
Key Terms

Abstract Background About a third of the world’s population will develop a mental disorder over their lifetime. Having a mental disorder is a huge burden in health loss and cost for the individual, but also for society because of treatment cost, production loss and caregivers’ cost. The objective of this study is to synthesize the international published literature on the economic burden of mental disorders. Methods Systematic literature searches were conducted in the databases PubMed, Embase, Web of Science, EconLit, NHS York Database and PsychInfo using key terms for cost and mental disorders. Searches were restricted to 1980 until May 2019. The inclusion criteria were: (1) cost-of-illness studies or cost-analyses; (2) diagnosis of at least one mental disorder (3) samples based on the general population; (4) outcome in monetary units. 13,640 publications were screened by their title/abstract and 439 articles were full-text screened by two independent reviewers. 113 articles were included from the systematic searches and 31 articles from snowball searching, giving a total of 144 included articles. Of these, 41 studies had estimates of the economic burden among people with schizophrenia. Results Information about diagnosis, diagnostic criteria, sample size, age, sex, data sources, study perspective, study period, costing approach, cost categories, discount rate and production loss method and cost unit was extracted. The preliminary results show a substantial variety in the used perspective, methodology, costs components and outcomes in the included studies. An online tool is under development enabling the reader to explore the published information on costs by type of mental disorder, subgroups, country, methodology, and study quality. Discussion To the best of our knowledge, this is the first systematic review synthesizing the economic cost of mental disorders worldwide. The paper will provide an important and comprehensive overview over the economic burden of mental disorders, and the output from this review will inform policy-making.

scholarly journals A Systematic Search and Review of Questionnaires Measuring Individual psychosocial Factors Predicting Return to Work After Musculoskeletal and Common Mental Disorders

2020 ◽  
Author(s):  
Andrea Gragnano ◽  
Patrizia Villotti ◽  
Christian Larivière ◽  
Alessia Negrini ◽  
Marc Corbière
Keyword(s):  
Mental Disorders ◽  
Return To Work ◽  
Psychosocial Factors ◽  
Self Efficacy ◽  
Common Mental Disorders ◽  
Grey Literature ◽  
Point Of View ◽  
Systematic Search ◽  
Multiple Item ◽  
The Individual

AbstractPurpose Individual psychosocial factors are crucial in the return to work (RTW) process of workers with musculoskeletal disorders (MSDs) and common mental disorders (CMDs). However, the quality and validity of the questionnaires used to measure these factors have rarely been investigated. The present systematic search and literature review aims at identifying, categorizing, and evaluating the questionnaires (measurement tools) used to measure individual psychosocial factors related to the perception of the personal condition and motivation to RTW that are predictive of successful RTW among workers with MSDs or CMDs. Methods Through a systematic search on PubMed, Web of Science, and PsycINFO library databases and grey literature, we identified the individual psychosocial factors predictive of successful RTW among these workers. Then, we retrieved the questionnaires used to measure these factors. Finally, we searched for articles validating these questionnaires to describe them exhaustively from a psychometric and practical point of view. Results: The review included 76 studies from an initial pool of 2263 articles. Three common significant predictors of RTW after MSDs and CMDs emerged (i.e., RTW expectations, RTW self-efficacy, and work ability), two significant predictors of RTW after MSDs only (i.e., work involvement and the self-perceived connection between health and job), and two significant predictors of RTW after CMDs only (i.e., optimism and pessimism). We analyzed 30 questionnaires, including eight multiple-item scales and 22 single-item measures. Based on their psychometric and practical properties, we evaluated one of the eight multiple-item scales as questionable and five as excellent. Conclusions: With some exceptions (i.e., self-efficacy), the tools used to measure individual psychosocial factors show moderate to considerable room for improvement.

Morphological subclassification of follicular lymphoma: variability of diagnoses among hematopathologists, a collaborative study between the Repository Center and Pathology Panel for Lymphoma Clinical Studies.

1985 ◽  
Vol 3 (1) ◽  
pp. 25-38 ◽  
Author(s):  
G E Metter ◽  
B N Nathwani ◽  
J S Burke ◽  
C D Winberg ◽  
R B Mann ◽  
...  
Keyword(s):  
Follicular Lymphoma ◽  
Clinical Studies ◽  
Accurate Determination ◽  
Collaborative Study ◽  
Estimation Method ◽  
Great Variability ◽  
Mixed Cell ◽  
The Individual ◽  
Follicular Lymphomas ◽  
Consensus Diagnosis

A collaborative study between the Repository Center for Lymphoma Clinical Studies and the members of the lymphoma pathology subcommittee of the major cooperative oncology groups was undertaken in an effort to ascertain the reproducibility and the interobserver agreement for the cytologic diagnosis of follicular lymphomas. A group of 105 patients with follicular lymphomas were subclassified by seven hematopathologists according to two methods. In the first method, cases were subclassified according to the Rappaport, Lukes, and Collins, and Working Formulation systems. In these systems, follicular lymphomas are subclassified by estimation of the different cell populations without the actual counting of cells. With this method, great variability in diagnosis was noted. For example: (1) The consensus diagnosis was that of poorly differentiated lymphocytic lymphoma (PDL) in 39 cases, but among the individual pathologists the number of cases thus diagnosed ranged from 24 to 65; (2) In 40 cases, the consensus diagnosis was follicular lymphoma, mixed-cell type; however, all seven pathologists independently agreed on this subtype in only one case; (3) A major disagreement was noted in 39 cases (37%), in which both diagnostic extremes (small cleaved and large noncleaved) were expressed. In the second method, only precise counts of different cells were made, according to a modification of the method recommended by Berard. With this counting method, diagnoses were independently derived based on the counts provided by the seven pathologists for large cleaved, small noncleaved, and large noncleaved cells. The variability in the results was wide also with this second method. For example, the average number of large cells found by each pathologist was ascertained, and the ranges were determined. The average range was 28 cells, which was considered high. The same determinations were performed only for large noncleaved cells, and the range was found to be 15 cells, which was also considered high. When the diagnoses derived from counts of only large noncleaved cells were compared with the traditional, more subjective diagnoses, fairly close agreement was obtained. In summary, the great variability in diagnoses of follicular lymphomas among pathologists may be attributed to the difficulties inherent in accurate determination of cell size and of the precise percentages of different cells. Until solutions to these problems are developed, one can subclassify follicular lymphomas according to the Berard method or the estimation method.

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