EPID-24. OBESITY IN MALES WITH MENINGIOMA: A U.S. POPULATION-BASED STUDY

Abstract BACKGROUND The female predominance of meningiomas may reflect a hormonal influence on tumorigenesis. Obesity alters steroid synthesis and chronically exposes men to hyperestrogenemia. OBJECTIVE Identify differences in males undergoing craniotomy for meningioma compared to other tumors or aneurysms. METHODS The National Surgical Quality Improvement Program was retrospectively queried from 2013–2018 for cases of craniotomy for resection of meningioma, other tumor, and aneurysm by CPT code in male patients and confirmed with postoperative ICD-10 code. Height and weight data were used to create body mass index (BMI): underweight (< 18.5), normal (18.5 to< 25), overweight (25 to< 30), class I obesity (30 to< 35), class II obesity (35 to< 40), and class III obesity (40+). RESULTS We identified 2,458 males who underwent craniotomy for meningioma, 9,889 for other tumor, and 386 for aneurysm. Using multivariable logistic regression, age (OR 1.01 per year, 95% CI 1.01-1.01, p< 0.001), diabetes mellitus (OR 1.32, 95% CI 1.17–1.48, p< 0.001), and increasing BMI (overweight: OR 1.55, 95% CI 1.36–1.76, p< 0.001; class I: OR 2.00, 95% CI 1.75–2.30, p< 0.0001; class II: OR 2.05, 95% CI 1.24–1.76, p< 0.001; class III: OR 1.47, 95% CI 1.24–1.76, p< 0.0001) were significantly and independently associated with craniotomy for meningioma compared to other tumor or aneurysm. For other tumor, higher BMI was associated with lower likelihood (overweight: OR 0.70, 95% CI 0.62–0.79, p< 0.001; class I: OR 0.55, 95% CI 0.49–0.63, p< 0.001; class II: OR 0.52, 95% CI 0.44–0.62, p< 0.001; class III: OR 0.74, 95% CI 0.63–0.87, p< 0.001). For aneurysm, there was no significant difference (overweight p=0.70; class I p=0.65; class II p=0.76; class III p=0.57). CONCLUSIONS BMI independently predicts having craniotomy for meningioma when compared to other tumor or aneurysm amongst US male patients.

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The duration of pubertal growth peak among three skeletal classes

Dental Press Journal of Orthodontics ◽

10.1590/2177-6709.21.5.067-074.oar ◽

2016 ◽

Vol 21 (5) ◽

pp. 67-74 ◽

Cited By ~ 3

Author(s):

Waqar Jeelani ◽

◽

Mubassar Fida ◽

Attiya Shaikh ◽

◽

...

Keyword(s):

Class Ii ◽

Growth Potential ◽

Class I ◽

Maturation Stage ◽

Class Iii ◽

Pubertal Growth ◽

Lateral Cephalograms ◽

Wide Range ◽

Significant Difference ◽

The Mean

ABSTRACT Introduction: Pubertal growth peak is closely associated with a rapid increase in mandibular length and offers a wide range of therapeutic modifiability. Objective: The aim of the present study was to determine and compare the mean ages of onset and duration of pubertal growth peak among three skeletal classes. Methods: A retrospective cross-sectional study was conducted using lateral cephalograms of 230 subjects with growth potential (110 males, 120 females). Subjects were categorized into three classes (Class I = 81, Class II = 82, Class III = 67), according to the sagittal relationship established between the maxilla and the mandible. The cervical vertebral maturation stage was recorded by means of Baccetti's method. The mean ages at CS3 and CS4 and the CS3-CS4 age interval were compared between boys and girls and among three skeletal classes. Results: Pubertal growth peak occurred on average four months earlier in girls than boys (p = 0.050). The average duration of pubertal growth peak was 11 months in Class I, seven months in Class II and 17 months in Class III subjects. Interclass differences were highly significant (Cohen's d > 0.08). However, no significant difference was found in the timing of pubertal growth peak onset among three skeletal classes (p = 0.126 in boys, p = 0.262 in girls). Conclusions: Girls enter pubertal growth peak on average four months earlier than boys. Moreover, the duration of pubertal growth peak is on average four months shorter in Class II and six months longer in Class III subjects as compared to Class I subjects.

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Prevalence of malocclusion in north Cyprus School

10.21203/rs.2.14715/v1 ◽

2019 ◽

Author(s):

Nadejda Beleva ◽

Nazli Idil Kacamak ◽

Cagla Sin ◽

Beste Kamiloglu

Keyword(s):

Orthodontic Treatment ◽

Class Ii ◽

Class I ◽

Correct Identification ◽

Class Iii ◽

Dental Services ◽

National Education ◽

Northern Cyprus ◽

Male Patients ◽

Division 2

Abstract Background. The epidemiology of the population living in a country plays an important role in the planning and implementation of dental services. Correct identification of the need for orthodontic treatment in individuals is a very complex subject and requires detailed analysis. The aim of this study was to measure the prevalence of malocclusion among randomly selected subjects aged 12-15 years attending secondary schools regardless of any socio-economic or social status in Northern Cyprus.Methods. After the approval of the competent authorities in the Ministry of National Education and the Ministry of Health of Northern Cyprus and of the parents whose subjects were to take part in the study, the evaluation was carried out by a team of three people, two of whom are in the process of specializing in orthodontics and one doctoral student at the qualification stage. The study included a randomly selected sampling composed of 426 subjects (203 females and 223 males). Results. The statistical evaluation of the samples collected in the study found that 20.6% of the subjects had no occurrence of occlusion, 74.4% had Class I, 21.1% had Class II (part 1, 18.8%, part 2, 2.3%) and 4.5% had Class III malocclusion. Of the 419 patients, 86 (20.2%) were in need of orthodontic treatment. Although not statistically significant, it was determined that 19.7% of female patients and 20.7% of the male patients were in need for orthodontic treatment.Conclusions. The most common orthodontic malocclusion in Cyprus is Class I, the least common malocclusion is Class II division 2.

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Association and Time-Varying Effects of Body Mass Index on All-Cause Mortality in Patients With Hypertension

10.21203/rs.3.rs-101453/v1 ◽

2020 ◽

Author(s):

jingjing zhu ◽

Xiaohua Liu ◽

Jinling Zhang ◽

Jun Li ◽

Linli Chen ◽

...

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Class Ii ◽

Class I ◽

Time Varying ◽

Protective Effects ◽

Class I Obesity ◽

Significant Difference ◽

All Cause Mortality

Abstract BackgroundThe relationship between body mass index (BMI) and mortality in hypertension patients remains controversial. This study aimed to evaluate the association and the time-varying effects of different BMI categories on the risk of all-cause mortality in hypertension patients. MethodsThis retrospective cohort study was conducted among 212,394 Chinese people with hypertension. All deaths were identiﬁed based on Shanghai Vital Statistics. Cox model combined with time-by-covariate interactions was used to estimate the association and the time-varying effects of BMI on the risk of all-cause mortality. The potential non-linear effects across follow-up period for BMI were examined by the application of restricted cubic spline (RCS).ResultsOverall, 31,130 deaths occurred (14.7%) within an average follow-up of 8.24 years. Underweight (<18.5 kg/m2) showed a progressively weakening negative effect on all-cause mortality over time. For both sexes, overweight (23.0-24.9 kg/m2) and class I obesity (25.0-29.9 kg/m2) showed protective effects within 5 years after registration, but these became insignificant in later years. There was no significant difference in the effect on all-cause mortality between class II obesity (≥30.0 kg/m2) and normal weight. in the elderly patients, overweight, class I obesity and class II obesity had continuous protective effects on mortality.ConclusionsAlthough the effect of baseline body mass index on the risk of all-cause mortality varied at different follow-up periods, underweight persistently remained a risk factor for all-cause mortality in hypertension, whereas overweight and class I obesity had protective effects. Thus, in the long-term management of hypertension, more attention should be given to underweight patients.

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Differences in the Buccal Bone Marrow Distance of ≤0.8 mm in the Mandible of Patients Undergoing Sagittal Split Ramus Osteotomy among the Different Skeletal Patterns: A Retrospective Study

Journal of Clinical Medicine ◽

10.3390/jcm10235644 ◽

2021 ◽

Vol 10 (23) ◽

pp. 5644

Author(s):

Yu-Chuan Tseng ◽

Shih-Wei Liang ◽

Szu-Ting Chou ◽

Shih-Chieh Chen ◽

Chin-Yun Pan ◽

...

Keyword(s):

Bone Marrow ◽

Class Ii ◽

B Value ◽

Class I ◽

Occurrence Rate ◽

Class Iii ◽

Sagittal Split Ramus Osteotomy ◽

Lower Lip ◽

B Values ◽

Significant Difference

This study investigated the relationship between the thickness of the ramus and skeletal patterns using cone-beam computed tomography (CBCT) for sagittal split ramus osteotomy. Ninety participants were categorized into three skeletal patterns (Class I, Class II, and Class III). The first vertical slice (slice 0) was observed in the intact mandibular canal, and then moved forward to 40 mm (slice 21) with a 2 mm interval. The thickness of buccal bone marrow (B value) was measured. A B value of ≤0.8 mm was considered to be the major risk factor causing the occurrence of postoperative lower lip paresthesia. There were 461 sides with a B value of ≤0.8 mm. There was a significant difference in the skeletal patterns [Class III (198 sides: 15.7%) > Class I (159 sides: 12.6%) > Class II (104 sides: 8.3%)]. Class II participants had significantly larger B values (2.14 to 3.76 mm) and a lower occurrence rate (≤0.8 mm) than those of Class III participants (1.5 to 3 mm) in front of the mandibular foramen (from 6 mm to 20 mm). Class III participants had significantly shorter buccal bone marrow distance and a higher occurrence rate of B values (≤0.8 mm) than Class II.

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Skull bone thickness versus malocclusion

APOS Trends in Orthodontics ◽

10.4103/2321-1407.169951 ◽

2015 ◽

Vol 5 ◽

pp. 255-261

Author(s):

D. K. Mahamad Iqbal ◽

Vivek B. Amin ◽

Rohan Mascarenhas ◽

Akther Husain

Keyword(s):

Class Ii ◽

Parietal Bone ◽

Frontal Bone ◽

Class I ◽

Class Ii Malocclusion ◽

Class Iii ◽

Class Iii Malocclusion ◽

Bone Thickness ◽

Significant Difference ◽

Skull Thickness

Objective The objectives of this study were to determine the thickness of skull bones, namely frontal, parietal, and occipital bones in Class I, Class II, and Class III patients. Materials and Methods Three hundred subjects who reported to the Department of Orthodontics requiring orthodontic treatment within the age group 17-35 were selected for the study. They were subdivided into three groups of 100 each according to the skeletal and dental relation. Profile radiographs were taken and the tracings were then scanned, and uploaded to the MATLAB 7.6.0 (R 2008a) software. The total surface areas of the individual bones were estimated by the software, which represented the thickness of each bone. Result Frontal bone was the thickest in Class III malocclusion group and the thinnest in Class II malocclusion group. But the parietal and occipital bone thickness were not significant. During gender differentiation in Class I, malocclusion group frontal bone thickness was more in males than females, In Class II, malocclusion parietal bone thickness was more in males than females. No statistically significant difference exists between genders, in Class III malocclusion group. During inter-comparison, the frontal bone thickness was significant when compared with Class I and Class II malocclusion groups and Class II and Class III malocclusion groups. Conclusion The differences in skull thickness in various malocclusions can be used as an adjunct in diagnosis and treatment planning for orthodontic patients. It was found that the new method (MATLAB 7.6.0 [R 2008a] software) of measuring skull thickness was easier, faster, precise, and accurate.

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Evaluating Distance between Vibrating Line and Fovea Palatinae in Class I, Class II and Class III Soft Palate Types

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2020/v32i4331073 ◽

2021 ◽

pp. 78-86

Author(s):

Bharat Kumar ◽

Muhammad Abbas ◽

Asma Naz ◽

Naresh Kumar ◽

Shahid Ali ◽

...

Keyword(s):

Statistical Analysis ◽

Oral Health ◽

Soft Palate ◽

Class Ii ◽

Health Sciences ◽

Class I ◽

Age Group ◽

Class Iii ◽

Significant Difference ◽

The Mean

Objective: The objective of this study was to evaluate the mean distance between the vibrating line and fovea palatinae in Class I, Class II and Class III Soft Palate types. Methodology: This study was conducted at Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences Karachi among 197patients. Duration of study was six months. All patients were examined for vibrating line clinically, assessed using phonation method. Subsequently, distance between vibrating line and fovea paltatinae was measured with uncalibrated compass in various contours of soft palate. Results: Out of 197 patient, the vibrating line was seen in130 (64%) anterior to fovea palatinae, whereas, 67 (34%) vibrating line was at the fovea palatinae. The mean distance of those anterior located vibrating line from fovea palatine was calculated as 2.13 (±0.82) mm in Class, 2.07 (±0.69) mm in Class II and 1.80 (±0.82) mm in Class III soft palate contours. Statistical analysis showed no significant between gender, while statistically significant difference among age group and mean distance of anterior located vibrating line from fovea palatinae were found. Conclusions: The mean distance of vibrating line which is predominately found anterior to the fovea palatinae was 2.07 (±0.77) mm.

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RELATIONSHIP BETWEEN OCCLUSAL PLANE ORIENTATION AND SAGITTAL MALOCCLUSIONS: STUDY OF AN ORTHODONTIC POPULATION

Innovare Journal of Social Sciences ◽

10.22159/ijss.2021.v9i3.41058 ◽

2021 ◽

pp. 1-6

Author(s):

INES DALLEL ◽

SANA KANOUN ◽

MARIEM NAHDI ◽

MONCEF OMMEZINE ◽

SAMIR TOBJI ◽

...

Keyword(s):

Orthodontic Treatment ◽

Class Ii ◽

Significant Rise ◽

Class I ◽

Occlusal Plane ◽

Class Iii ◽

Angle Class ◽

Mandibular Plane ◽

Significant Difference ◽

Skeletal Pattern

Objective: The aim of this study was to evaluate the association of the skeletal pattern and angle class with the occlusal plane (OP). This study also examined the effect of orthodontic treatment on this plane. Methods: Lateral cephalometric radiographs of a sample of 135 patients were collected. The angles between the Frankfort horizontal, palatal plane (PP), mandibular plane (MP), and the OP were analyzed and compared between several groups and subsequently before and after treatment. Results: The statistical comparison between 3 skeletal frame groups demonstrates that the cant of the OP showed a major difference. This difference was greater in class III subjects. Examination revealed that the OP was not meaningfully affected within the Angle classification. Statistically, a significant correlation was found between OP steepness and the vertical skeletal pattern. A significant rise of OP/sella-nasion (SN) for class I (p=0.019) and II (p=0.015) after orthodontic treatment. In addition, patients treated with elastics showed a significant decrease of OP/MP (mandibular plane) in Angle class III and considerable increase of OP/SN and OP/PP in Angle class II. Observations of the group treated with bimaxillary extractions showed that OP/SN (sella nasion line) and OP/PP differ in a meaningful way. Conclusion: This study confirms the association between the skeletal pattern and the OP inclination in adults. Concerning the Angle classification, there was no significant difference between the groups. Orthodontic therapy had an influence on the inclination of this plane for the different malocclusions. Premolars extraction in class I cases significantly modified the OP. For class II and III malocclusions, the OP inclination was mainly altered by the use of intermaxillary traction elastics.

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Mild and Severe Obesity Reduce the Effectiveness of Lumbar Fusions: 1-Year Patient-Reported Outcomes in 8171 Patients

Neurosurgery ◽

10.1093/neuros/nyaa414 ◽

2020 ◽

Author(s):

Graham Mulvaney ◽

Olivia M Rice ◽

Vincent Rossi ◽

David Peters ◽

Mark Smith ◽

...

Keyword(s):

Risk Factor ◽

Surgical Complications ◽

Surgical Complication ◽

Lumbar Fusion ◽

Class Ii ◽

Class I ◽

Class Iii ◽

Class I Obesity ◽

Patient Reported ◽

One Year

Abstract BACKGROUND Elevated body mass index (BMI) is a well-known risk factor for surgical complications in lumbar surgery. However, its effect on surgical effectiveness independent of surgical complications is unclear. OBJECTIVE To determine increasing BMI’s effect on functional outcomes following lumbar fusion surgery, independent of surgical complications. METHODS We retrospectively analyzed a prospectively built, patient-reported, quality of life registry representing 75 hospital systems. We evaluated 1- to 3-level elective lumbar fusions. Patients who experienced surgical complications were excluded. A stepwise multivariate regression model assessed factors independently associated with 1-yr Oswestry Disability Index (ODI), preop to 1-yr ODI change, and achievement of minimal clinically important difference (MCID). RESULTS A total of 8171 patients met inclusion criteria: 2435 with class I obesity (BMI 30-35 kg/m2), 1328 with class II (35-40 kg/m2), and 760 with class III (≥40 kg/m2). Increasing BMI was independently associated with worse 12-mo ODI (t = 8.005, P < .001) and decreased likelihood of achieving MCID (odds ratio [OR] = 0.977, P < .001). One year after surgery, mean ODI, ODI change, and percentage achieving MCID worsened with class I, class II, and class III vs nonobese cohorts (P < .001) in stepwise fashion. CONCLUSION Increasing BMI is associated with decreased effectiveness of 1- to 3-level elective lumbar fusion, despite absence of surgical complications. BMI ≥ 30 kg/m2 is, therefore, a risk factor for both surgical complication and reduced benefit from lumbar fusion.

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Evaluation of horizontal condylar angle in malocclusions with mandibular lateral displacement using cone-beam computed tomography

The Angle Orthodontist ◽

10.2319/012621-76.1 ◽

2021 ◽

Author(s):

Roberto L. Velásquez ◽

Jorge C. Coro ◽

José M. Bustillo ◽

Sadao Sato

Keyword(s):

Computed Tomography ◽

Cone Beam Computed Tomography ◽

Lateral Displacement ◽

Class Ii ◽

Contralateral Side ◽

Class I ◽

Cone Beam ◽

Class Iii ◽

Skeletal Class ◽

Significant Difference

ABSTRACT Objectives To evaluate the horizontal condylar angle (HCA) in mandibular lateral displacement (MLD). Materials and Method s: HCA in MLD malocclusions were examined using cone-beam computed tomography data in subjects with MLD and control subjects. Results HCA in joints of control patients and contralateral side joints of MLD patients were not significantly different. The mean HCA on the shifted side was larger than on the contralateral side (P < .001) in the different HCA groups. HCA was significantly larger on the shifted side than on the contralateral side in skeletal Class I, Class II, and Class III groups (P < .001). Conclusions (1) There was no statistically significant difference between HCA in control patients and on the contralateral side in MLD patients. (2) HCA was significantly larger on the shifted side than on the contralateral side. (3) HCA on the shifted side and the contralateral side in MLD Class I, Class II, and Class III are significantly different.

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Analysis of Facial Skeletal Morphology: Nasal Bone, Maxilla, and Mandible

BioMed Research International ◽

10.1155/2021/5599949 ◽

2021 ◽

Vol 2021 ◽

pp. 1-9

Author(s):

Han-Sheng Chen ◽

Szu-Yu Hsiao ◽

Kun-Tsung Lee

Keyword(s):

Correlation Coefficient ◽

Body Length ◽

Nasal Bone ◽

Class Ii ◽

Class I ◽

Class Iii ◽

Bone Length ◽

Significant Difference ◽

Mandibular Body ◽

Nasal Bone Length

The growth and development of facial bones are closely related to each other. The present study investigated the differences in the nasomaxillary and mandibular morphology among different skeletal patterns. Cephalograms of 240 participants were divided into 3 groups based on the skeletal pattern (Class I, Class II, and Class III). The dimensions of nasomaxilla (nasal bone length, nasal ridge length, nasal depth, palatal length, and maxillary height) and mandible (condylar length, ramus length, body length, symphysis length, and entire mandibular length) were measured. One-way analysis of variance and Pearson’s correlation test were used for statistical analysis. No significant differences were observed among the skeletal patterns in terms of nasal bone length, palatal length, maxillary height, or condylar length. Class II had a significantly shorter ramus, mandibular body, and entire mandibular length compared with those of Class I and Class III. Nasal ridge length exhibited a significant moderate correlated with nasal bone length (correlation coefficient: 0.433) and maxillary height (correlation coefficient: 0.535). The entire mandibular length exhibited a significant moderate correlated with ramus length (correlation coefficient: 0.485) and body length (correlation coefficient: 0.536). In conclusion, nasal and maxillary dimensions exhibited no significant difference among the 3 skeletal patterns. Mandibular body and entire mandibular lengths were significantly positively correlations with Class III skeletal patterns.

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