Epilogue

2021 ◽  
pp. 217-220
Author(s):  
Kevin Winkler
Keyword(s):  
The Past ◽  
Lifetime Achievement ◽  
Show Business ◽  
New Generation ◽  
Small Platform ◽  
Grand Hotel ◽  
Elemental Form

By the time Tommy Tune received a special Tony Award for Lifetime Achievement in 2015, he had inspired a new generation of director-choreographers, including Susan Stroman, Jerry Mitchell, and Casey Nicholaw. They successfully adapted Tune’s seamless staging concepts, his use of show business motifs, and his ability to move forward by drawing on the past to a new, faster-paced era. Well into his seventies, Tune continued to create shows with precision and detail, but now they were of a much smaller scale and featured a cast of one. His solo traveling act took on a biographical air, with recollections of his theatrical past performed on a bare stage with just a small platform for dancing, a ladder, and evocative lighting. It was the simplicity and elegance of Nine, Grand Hotel, and My One and Only stripped to their most elemental form. For Tune, everything was still choreography, but on a diminutive scale.

The Contribution of Intermediate-Voltage, High-Resolution Electron Microscopy In Materials Science: An Appraisal

1990 ◽  
Vol 48 (1) ◽  
pp. 478-479
Author(s):  
John L. Hutchison
Keyword(s):  
High Resolution ◽  
Materials Science ◽  
High Resolution Electron Microscopy ◽  
Optical Diffraction ◽  
The Past ◽  
Resolution Electron ◽  
Extreme Sensitivity ◽  
Electron Microscopes ◽  
New Generation ◽  
Small Metal Particles

Over the past five years or so the development of a new generation of high resolution electron microscopes operating routinely in the 300-400 kilovolt range has produced a dramatic increase in resolution, to around 1.6 Å for “structure resolution” and approaching 1.2 Å for information limits. With a large number of such instruments now in operation it is timely to assess their impact in the various areas of materials science where they are now being used. Are they falling short of the early expectations? Generally, the manufacturers’ claims regarding resolution are being met, but one unexpected factor which has emerged is the extreme sensitivity of these instruments to both floor-borne and acoustic vibrations. Successful measures to counteract these disturbances may require the use of special anti-vibration blocks, or even simple oil-filled dampers together with springs, with heavy curtaining around the microscope room to reduce noise levels. In assessing performance levels, optical diffraction analysis is becoming the accepted method, with rotational averaging useful for obtaining a good measure of information limits. It is worth noting here that microscope alignment becomes very critical for the highest resolution.In attempting an appraisal of the contributions of intermediate voltage HREMs to materials science we will outline a few of the areas where they are most widely used. These include semiconductors, oxides, and small metal particles, in addition to metals and minerals.

Molecular Epidemiology and Biomarkers in Etiologic Cancer Research: The New in Light of the Old

2020 ◽  
Author(s):  
Lungwani Muungo
Keyword(s):  
Gene Expression ◽  
Cancer Research ◽  
Molecular Epidemiology ◽  
Exposure Assessment ◽  
Large Scale ◽  
First Generation ◽  
Cancer Epidemiology ◽  
Policy Changes ◽  
The Past ◽  
New Generation

The purpose of this review is to evaluate progress inmolecular epidemiology over the past 24 years in canceretiology and prevention to draw lessons for futureresearch incorporating the new generation of biomarkers.Molecular epidemiology was introduced inthe study of cancer in the early 1980s, with theexpectation that it would help overcome some majorlimitations of epidemiology and facilitate cancerprevention. The expectation was that biomarkerswould improve exposure assessment, document earlychanges preceding disease, and identify subgroupsin the population with greater susceptibility to cancer,thereby increasing the ability of epidemiologic studiesto identify causes and elucidate mechanisms incarcinogenesis. The first generation of biomarkers hasindeed contributed to our understanding of riskandsusceptibility related largely to genotoxic carcinogens.Consequently, interventions and policy changes havebeen mounted to reduce riskfrom several importantenvironmental carcinogens. Several new and promisingbiomarkers are now becoming available for epidemiologicstudies, thanks to the development of highthroughputtechnologies and theoretical advances inbiology. These include toxicogenomics, alterations ingene methylation and gene expression, proteomics, andmetabonomics, which allow large-scale studies, includingdiscovery-oriented as well as hypothesis-testinginvestigations. However, most of these newer biomarkershave not been adequately validated, and theirrole in the causal paradigm is not clear. There is a needfor their systematic validation using principles andcriteria established over the past several decades inmolecular cancer epidemiology.

Vēsturiskā atmiņa Latvijas teātra jaunās paaudzes mākslinieku darbos: izrādes „Dvēseļu utenis” piemērs

2020 ◽  
pp. 269-275
Author(s):  
Ieva Rodiņa
Keyword(s):  
Historical Memory ◽  
Intergenerational Relationships ◽  
Phenomenological Approach ◽  
Political Theater ◽  
Hermeneutic Phenomenological ◽  
The Past ◽  
The Social ◽  
Humanistic Study ◽  
New Generation ◽  
Flea Market

The aim of the research “Historical Memory in the Works of the New Generation of Latvian Theater Artists: The Example of “The Flea Market of the Souls” is to focus on the current but at the same time little discussed topic in Latvian theater – the change of generations and the social processes connected to it, that are expressed on the level of world views, experiences, intergenerational relationships. Most directly, these changes are reflected in the phenomenon of historical memory. The concept of “postmemory” was defined by German professor Marianne Hirsch in 1992, suggesting that future generations are closely related to the personal and collective cultural traumas of previous generations, which are passing on the past experience through historical memory, thus affecting the present. Grotesque, self-irony, and focusing on socio-political, provocative questions and themes are the connecting point of the generation of young Latvian playwrights born in the late 1980s and early 1990s, including such personalities as Jānis Balodis, Rasa Bugavičute-Pēce, Matīss Gricmanis, Justīne Kļava, etc. However, unlike Matīss Gricmanis or Janis Balodis who represent the aesthetics of political theater, in Justīne Kļava’s works, sociopolitical processes become the background of a generally humanistic study of the relationships between generations. This theme is represented not only in “The Flea Market of the Souls”, but also in other plays, like “Jubilee ‘98” and “Club “Paradise””. The tendency to investigate the traces left by the Soviet heritage allows to define these works as autobiographical researches of the identity of the post-Soviet generation, analyzing life in today's Latvia in terms of historical memory. Using the semiotic, hermeneutic, phenomenological approach, the play “The Flea Market of the Souls” and its production in Dirty Deal Teatro (2017) are analyzed as one of the most vivid works reflecting the phenomenon of historical memory in recent Latvian original drama.

The Twenty-first Century

2018 ◽  
Author(s):  
Alexander Gillespie
Keyword(s):  
Environmental Sustainability ◽  
First Century ◽  
Bad News ◽  
Good News ◽  
Species Loss ◽  
The Past ◽  
Scientific Terms ◽  
Twenty First Century ◽  
Open Question ◽  
New Generation

The cumulative environmental challenge of sustainable development in the twenty-first century is larger than anything humanity has ever had to deal with in the past. The good news is that solid progress is being reached in the understanding of issues in scientific terms and understanding what needs to be done. The bad news is twofold. First, although many of the environmental problems of earlier centuries are now being confronted, a new generation of difficulties is eclipsing what were the older difficulties. Secondly, much of the progress is being achieved by the wealthier parts of the planet, rather than the developing world. From population growth to climate change to unprecedented habitat and species loss, whether environmental sustainability can be achieved in the twenty-first century is an open question.

scholarly journals The evolution of Darwinian sexualities

BJHS Themes ◽  
2021 ◽  
pp. 1-23
Author(s):  
Erika Lorraine Milam
Keyword(s):  
Gay Rights ◽  
First Century ◽  
Sexual Practices ◽  
Past Century ◽  
Sexual Preferences ◽  
The Past ◽  
Sexual Behaviours ◽  
Late Twentieth ◽  
New Generation ◽  
Descent Of Man

Abstract Charles Darwin's Descent of Man was suffused with questions of courtship, mating and sex. Following in his footsteps, biologists throughout the twentieth century interrogated the sexual behaviour of humans and animals. This paper charts the fate of evolutionary theories of sexuality to argue that – despite legal and social gains of the past century – when biologists used sexual selection as a tool for theorizing the evolution of homosexual behaviour (which happened only rarely), the effect of their theories was to continuously reinscribe normative heterosexuality. If, at the end of the nineteenth century, certain sex theorists viewed homosexuality as a marker of intermediate sex, by the late twentieth a new generation of evolutionary theorists idealized gay men as hyper-masculine biological males whose sexual behaviours were uncompromised by the necessity of accommodating women's sexual preferences. In both cases, normative assumptions about gender were interwoven with those about sexuality. By the twenty-first century, animal exemplars were again mobilized alongside data gathered about human sexual practices in defence of gay rights, but this time by creating the opportunity for naturalization without recourse to biological determinism.

Quantifying sources and sinks of trace gases using space-borne measurements: current and future science

2008 ◽  
Vol 366 (1885) ◽  
pp. 4509-4528 ◽  
Author(s):  
Paul I Palmer
Keyword(s):  
Trace Gases ◽  
Lower Troposphere ◽  
Biological Interactions ◽  
Satellite Measurements ◽  
Sources And Sinks ◽  
The Past ◽  
Fundamental Understanding ◽  
Earth’S Climate ◽  
New Generation

We have been observing the Earth's upper atmosphere from space for several decades, but only over the past decade has the necessary technology begun to match our desire to observe surface air pollutants and climate-relevant trace gases in the lower troposphere, where we live and breathe. A new generation of Earth-observing satellites, capable of probing the lower troposphere, are already orbiting hundreds of kilometres above the Earth's surface with several more ready for launch or in the planning stages. Consequently, this is one of the most exciting times for the Earth system scientists who study the countless current-day physical, chemical and biological interactions between the Earth's land, ocean and atmosphere. First, I briefly review the theory behind measuring the atmosphere from space, and how these data can be used to infer surface sources and sinks of trace gases. I then present some of the science highlights associated with these data and how they can be used to improve fundamental understanding of the Earth's climate system. I conclude the paper by discussing the future role of satellite measurements of tropospheric trace gases in mitigating surface air pollution and carbon trading.

History and Theory in Anthropology

2021 ◽  
Author(s):  
Alan Barnard
Keyword(s):  
North America ◽  
New Developments ◽  
The Past ◽  
Award Winning ◽  
The World ◽  
The Subject ◽  
Post Colonialism ◽  
New Generation ◽  
History And Theory

In the past twenty years, there have been exciting new developments in the field of anthropology. This second edition of Barnard's classic textbook on the history and theory of anthropology has been revised and expanded to include up-to-date coverage on all the most important topics in the field. Its coverage ranges from traditional topics like the beginnings of the subject, evolutionism, functionalism, structuralism, and Marxism, to ideas about globalization, post-colonialism, and notions of 'race' and of being 'indigenous'. There are several new chapters, along with an extensive glossary, index, dates of birth and death, and award-winning diagrams. Although anthropology is often dominated by trends in Europe and North America, this edition makes plain the contributions of trendsetters in the rest of the world too. With its comprehensive yet clear coverage of concepts, this is essential reading for a new generation of anthropology students.

Recent Progress on Apoptotic Activity of Triazoles

2021 ◽  
Vol 22 ◽  
Author(s):  
Pelin Çıkla-Süzgün ◽  
Ş. Güniz Küçükgüzel
Keyword(s):  
Cancer Progression ◽  
Anticancer Agents ◽  
Heterocyclic Compounds ◽  
Rational Design ◽  
Vital Role ◽  
Anticancer Activities ◽  
The Past ◽  
Small Molecule Drugs ◽  
Apoptotic Activity ◽  
New Generation

Abstract: Apoptosis, often called programmed cell death, is a self-directed cell destruction process. It differs from classical necrosis by activation of caspases. Apoptosis is directly related to cancer progression and plays a vital role in carcinogenesis. All cytotoxic drugs and radiation therapy programs initiates apoptosis in tumor cells. Today, studies show that heterocyclic compounds that contain triazole funtionality have anticancer activities. Triazoles are 5-membered rings, which contain two carbon and three nitrogen atoms Therefore, many researchers have synthesized these small active compounds as target structures and evaluated their apoptotic activities. The present review describs more recent medicinal aspects of triazoles as anticancer agents reported during the past few years. We hope that the bioactivity of triazole derivatives will be beneficial for the rational design of new generation of small molecule drugs.

Understanding and exploiting the genetics of plant root traits

2021 ◽  
pp. 395-466
Author(s):  
Roberto Tuberosa ◽  
◽  
Elisabetta Frascaroli ◽  
Marco Maccaferri ◽  
Silvio Salvi ◽  
...  
Keyword(s):  
Environmental Impact ◽  
Plant Root ◽  
Root Traits ◽  
The Past ◽  
Vast Literature ◽  
New Generation Sequencing ◽  
New Generation ◽  
Constrained Conditions ◽  
Major Emphasis ◽  
Generation Sequencing

This chapter illustrates how genomics and other -omics approaches coupled with new-generation sequencing (NGS) platforms have been deployed to dissect the genetic make-up of RSA traits and better understand their functions, particularly under environmentally constrained conditions that commonly occur in most farmed soils. The major emphasis is devoted to studies during the past two decades in crops and only occasional reference is provided to the vast literature from RSA studies conducted in Arabidopsis and other model plants. The chapter also provides examples on how, in some cases, this knowledge is already benefiting farmers and how it can help in reducing the environmental impact of agriculture worldwide.

Flex-DIMM – A New High Density Module Form Factor

2015 ◽  
Vol 2015 (1) ◽  
pp. 000806-000809
Author(s):  
James E. Clayton
Keyword(s):  
Form Factor ◽  
Cross Section ◽  
Lower Layer ◽  
Signal Integrity ◽  
High Density ◽  
Thermal Dissipation ◽  
Ideal Solution ◽  
Memory Module ◽  
The Past ◽  
New Generation

The Dual In-Line Memory Module (DIMM) has remained relatively unchanged for the past two decades, with exception of an increase in PCB size, I/O pads and layer count. A new generation called Flex-DIMM is introduced by replacing the rigid-PCB substrate with a thin, bifurcated, flexible circuit that enables several improvements; including a thinner cross-section, better signal integrity with lower layer count, better thermal dissipation and ability to be directly mated to the surface of a motherboard. Originally intended for RDIMM applications, the new module may be an ideal solution for clustered microservers.

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