The Abnormalities of the Sunghir People

Author(s):  
Erik Trinkaus ◽  
Alexandra P. Buzhilova ◽  
Maria B. Mednikova ◽  
Maria V. Dobrovolskaya

Throughout the previous chapters detailing and comparing the Sunghir human remains, there have been frequent references to their abnormalities. Some of these unusual features are obvious and sufficiently pronounced as to remove the bones from direct paleobiological consideration (e.g., the Sunghir 1 pollical osteoarthrosis and the Sunghir 3 femoral diaphyses). Other features are modest and had no apparent effect on the functional anatomical interpretations (e.g., the Sunghir 1 ulnar carpometacarpal osteoarthrosis). A few aspects may modify either the considerations of the osteometric morphology (e.g., the Sunghir 1 frontal midline protrusion) or discrete traits (e.g., the Sunghir 2 dental asymmetries). Some of these features are obviously pathological and represent reflections of developmental or degenerative strains on the body (e.g., Sunghir 2 and 3 dental enamel hypoplasias (DEH), or the Sunghir 1 manual osteoarthrosis). Other aspects may not be pathological sensu stricto but they represent variations that push the limits of “normal” human variation (e.g., the Sunghir 1 femoral asymmetry and the Sunghir 3 foramina transversaria). These aspects that have been described in detail in previous chapters are referred to here, but the others, whose description has been deferred, are detailed in this chapter. A number of these abnormalities of the Sunghir human remains have been noted previously, beginning with Debetz’s (1967) initial observations on the Sunghir 1 skeleton, the initial description of the Sunghir 2 and 3 remains (Nikityuk and Kharitonov 1984), and Bukhman’s (1984) radiographic analysis of the Sunghir 3 remains. These and further observations and interpretations were made in the context of the 1990s’ reanalysis of the Sunghir remains (Buzhilova 2000b, 2000c; Mednikova 2000c, 2000d). There have subsequently been additional analyses of specific aspects of these abnormalities, including differential diagnosis of the Sunghir 3 femoral deformities (Formicola and Buzhilova 2004), description of the T1 injury to Sunghir 1 discovered in 2009 (Trinkaus and Buzhilova 2012), detailed assessment of the Sunghir 2 and 3 DEH (Guatelli-Steinberg et al. 2013), and assessment of the degree to which the deformities of Sunghir 3 might have affected her activity levels (Cowgill et al. 2012b).

2020 ◽  
Vol 86 ◽  
pp. 285-304
Author(s):  
Emilie Vannier

This paper concerns the architecture of formal burials from the La Tène period in north-western Gaul and southern Britain. The research focuses on the shape and dimensions of sepulchral pits containing inhumed or burnt human remains, on the different materials used for the internal elements, and the external constructions and structures covering, framing, or marking the burials. The study of these data exposes the preferred choices in the funerary architecture of Gallic and British communities during the last five centuries bc. The results reveal different regional funerary groups within three main cross-Channel zones according to the architectural elements of the graves and the main treatments of the body. The distinct characteristics of these groups highlight their common features and relationships with neighbouring areas of the Continental and Atlantic zones.


2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Daniele Casti ◽  
Christian Scarano ◽  
Maria Cristina Piras ◽  
Paolo Merella ◽  
Sonia Muglia ◽  
...  

Anisakiasis is a gastrointestinal fishborne zoonosis caused by the ingestion of third stage larvae of the genus <em>Anisakis</em>. Between January and December 2013, 1112 specimens of four commercial fish species (<em>Engraulis encrasicolus, Merluccius merluccius, Scomber colias</em> and <em>Trachurus mediterraneus</em>) marketed in Sardinia (Italy) were examined for <em>Anisakis</em> sp. The overall prevalence of <em>Anisakis</em> spp larvae was 39.9%, all morphologically identified as Type I. <em>Scomber colias</em> showed the highest prevalence (100%), followed by <em>M. merluccius</em> (Atlantic 91.0%, Mediterranean 71.2%), <em>T. mediterraneus</em> (32.7%) and <em>E. encrasicolus</em> (25.9%). All the larvae found in Mediterranean hosts were genetically identified as <em>Anisakis pegreffii</em>, whereas 90.0% of the larvae found in the Atlantic <em>M. merluccius</em> belonged to <em>Anisakis simplex sensu stricto</em> and 10.0% to <em>A. pegreffii</em>. The mean abundance of <em>Anisakis</em> sp. larvae was positively correlated with fish size in <em>E. encrasicolus</em>, Atlantic <em>M. merluccius</em> and local <em>M. merluccius</em>. The prevalence of infection was greater in the body cavity (37.9%) than in the edible muscle (9.4%). However, 1.8% of the examined fish were infected exclusively in the muscle. Therefore, the risk associated to the consumption of raw or undercooked fishery products poses the need of measures such as visual inspection and preventive treatments to guarantee consumers’ health.


Retos ◽  
2016 ◽  
pp. 271-274
Author(s):  
Manuela Costa ◽  
Tânia Oliveira ◽  
Jorge Mota ◽  
Maria Paula Santos ◽  
José Carlos Ribeiro

Objective: The objective of this study was twofold. First, analyze physical activity (PA) levels during physical education (PE) with different durations (45 and 90 minutes) according to student’s obesity status. Secondly, we examine the relative contribution of 45 and 90 minutes PE (45PE and 90PE) for the compliance of the daily PA recommendations according to the body mass index (BMI). Methods: Four public schools were analyzed. The sample comprised 472 youngsters (266 girls) aged between 10 and 18 years old. PA was assessed using an Actigraph accelerometer. The participants were categorized as non-overweight (NOW) and overweight/obese (OW) according to the sex-adjusted BMI. Results: The proportion of Moderate and Vigorous Physical Activity (MVPA) was lower than the 50% recommended by guidelines regardless the PE duration. Our data showed that only 26% of NOW and 13% of OW in the 45PE achieved the recommended levels while 17% of NOW and 11% of OW achieved the recommendation in 90PE. Overall, the 90PE had a higher absolute contribution for daily MVPA recommendations compliance than 45PE. Conclusion: During PE classes youngsters spent a reduced amount of time in MVPA, independently of their weight status.Resumen. Objetivo: Este estudio tiene un doble objetivo. En primero lugar, analizar los niveles de la actividad física durante la educación física con diferentes duraciones (45 y 90 minutos) de acuerdo con el estado de la obesidad de los alumnos. En segundo lugar, se analiza la contribución relativa de 45 y 90 minutos de la educación física para el cumplimiento de las recomendaciones diarias de actividad física según el índice de masa grasa. Métodos: cuatro escuelas públicas fueran analizadas. La muestra fue de 472 jóvenes (266 chicas) con edades entre los 10 y 18 años. La actividad física fue medida utilizando un acelerómetro Actigraph. Los participantes fueran clasificados como sin sobrepeso y con sobrepeso/obesidad de acuerdo con el índice de masa grasa ajustado al género. Resultados: La proporción de la actividad física moderada y vigorosa fue inferior al 50% recomendado por las recomendaciones independiente de la duración de la clase de educación física. Nuestros datos muestran que solo unos 26% de los niños sin sobrepeso y unos 13% de niñoss con sobrepeso/obesidad llegaron al los niveles recomendados en las clases de 45 min, mientras el 17% de los jóvenes sin sobrepeso y el 11% con sobrepeso/obesidad han logrado las recomendaciones en las clases de 90 min. En general, las clases de 90 min tienen una mayor contribución para cumplimiento de las recomendaciones diarias de actividad física moderada a vigorosa do que las clases de 45 min. Conclusión: Durante las clases de educación física los jóvenes tuvieran una cantidad reducida de tiempo en actividad física moderada a vigorosa, independiente de su estado de peso.


2020 ◽  
Vol 21 (23) ◽  
pp. 8952
Author(s):  
Keigo Yoshizaki ◽  
Satoshi Fukumoto ◽  
Daniel D. Bikle ◽  
Yuko Oda

Dental enamel is hardest tissue in the body and is produced by dental epithelial cells residing in the tooth. Their cell fates are tightly controlled by transcriptional programs that are facilitated by fate determining transcription factors and chromatin regulators. Understanding the transcriptional program controlling dental cell fate is critical for our efforts to build and repair teeth. In this review, we describe the current understanding of these regulators essential for regeneration of dental epithelial stem cells and progeny, which are identified through transgenic mouse models. We first describe the development and morphogenesis of mouse dental epithelium in which different subpopulations of epithelia such as ameloblasts contribute to enamel formation. Then, we describe the function of critical factors in stem cells or progeny to drive enamel lineages. We also show that gene mutations of these factors are associated with dental anomalies in craniofacial diseases in humans. We also describe the function of the master regulators to govern dental lineages, in which the genetic removal of each factor switches dental cell fate to that generating hair. The distinct and related mechanisms responsible for the lineage plasticity are discussed. This knowledge will lead us to develop a potential tool for bioengineering new teeth.


1942 ◽  
Vol 76 (1) ◽  
pp. 15-30 ◽  
Author(s):  
W. M. Balfour ◽  
P. F. Hahn ◽  
W. F. Bale ◽  
W. T. Pommerenke ◽  
G. H. Whipple

Radio iron is a tool which makes iron absorption studies quite accurate in dogs and reasonably satisfactory in human beings. This method is vastly superior to others previously used. Normal human pregnancy without significant anemia may show active radio iron absorption—16 to 27 per cent of iron intake. The pregnant woman as a rule shows 2 to 10 times the normal absorption of radio iron. Diseased states in which iron stores are known to be very abundant—pernicious anemia, hemochromatosis, familial icterus, and Mediterranean anemia —show very little absorption, probably less than normal. This is in spite of a severe anemia in all conditions except hemochromatosis. Chronic infections in spite of anemia show no utilization of radio iron, whether it may be absorbed or not. Leukemia shows little utilization of radio iron in red cells in spite of absorption (autopsy), probably because of white cells choking the red marrow. Polycythemia shows very low values for iron absorption as do normal persons. Two pregnant women showed only normal iron absorption. We believe that reserve stores of iron in the body, rather than anemia, control iron absorption. This control is exerted upon the gastro-intestinal mucosa which can refuse or accept iron under various conditions.


Author(s):  
Sally Arno ◽  
Rachel Forman ◽  
Philip Glassner ◽  
Ravinder Regatte ◽  
Peter S. Walker

During activities the knee experiences compressive forces caused by the weight of the body and muscle forces. However, there is also an anterior shear force pushing the femur forwards on the tibia. It is likely to be important to the feeling of stability that the shear force is resisted so as to limit the anterior femoral displacement. The dished bearing surface of the medial tibial compartment in combination with the medial meniscus may well perform this function. In contrast, the lateral tibial surface is convex in the sagittal plane and the meniscus is too mobile to offer any anteroposterior (AP) restraint. Therefore, we hypothesize that if an anterior or posterior force is applied to the femur relative to the tibia, AP stability is provided by the medial side, while the lateral side allows for femoral rollback to facilitate a high range of flexion. At any flexion angle, rotational laxity will occur about a point on the medial side.


2018 ◽  
Vol 33 (3) ◽  
pp. 183-190 ◽  
Author(s):  
Kevin Price ◽  
Alan HD Watson

AIMS: Though ergonomic supports are widely used for many groups of instruments, they are rare for brass instruments, despite the instruments’ considerable weight. Musculoskeletal injury and postural problems are common among this group, and so, both adult and young players are likely to benefit from supports that reduce the load placed on the body. This study assessed the effects on postural muscle activity of a recently developed range of supports (Ergobrass) that use a rod to transfer the weight of the instrument to a harness or to the chair or floor. METHODS: Twenty conservatoire students (mean age [SD], 20.9 ± 0.5 yrs) of the trumpet, french horn, or trombone used the supports while playing short brass studies, either sitting or standing. Surface electromyography recordings were made from key postural muscles, and their activity levels were compared with and without the support. RESULTS: Statistically significant reductions (typically 15–30%) were present in many of the muscles when using the supports, though in some players they were much larger. The number of muscles affected was least with the lightest instruments (the trumpet), with the effects mainly in the left deltoid and trapezius muscles. Reductions for the horn were bilateral, principally in biceps, pectoralis major, and deltoid; while in the trombone, they were confined to the left side (pectoralis major, posterior deltoid, and trapezius), as the right arm is in constant use to move the slide. CONCLUSIONS: The supports are effective in reducing postural muscle activity and may be of particular benefit to injured or young players.


2019 ◽  
Vol 13 (2) ◽  
pp. 67-80 ◽  
Author(s):  
Austin F. Mount-Campbell ◽  
Kevin D. Evans ◽  
David D. Woods ◽  
Esther M. Chipps ◽  
Susan D. Moffatt-Bruce ◽  
...  

We identify the value and usage of a cognitive artifact used by hospital nurses. By analyzing the value and usage of workaround artifacts, unmet needs using intended systems can be uncovered. A descriptive study employed direct observations of registered nurses at two hospitals using a paper workaround (“brains”) and the Electronic Health Record. Field notes and photographs were taken; the format, size, layout, permanence, and content of the artifact were analyzed. Thirty-nine observations, spanning 156 hr, were conducted with 20 nurses across four clinical units. A total of 322 photographs of paper-based artifacts for 161 patients were collected. All participants used and updated “brains” during report, and throughout the shift, most were self-generated. These artifacts contained patient identifiers in a header with room number, last name, age, code status, and physician; clinical data were recorded in the body with historical chronic issues, detailed assessment information, and planned activities for the shift. Updates continuously made during the shift highlighted important information, updated values, and tracked the completion of activities. The primary functional uses of “brains” are to support nurses’ needs for clinical immediacy through personally generated snapshot overviews for clinical summaries and updates to the status of planned activities.


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