Immune System Functioning and Mental Health

2016 ◽  
Author(s):  
Colin Jenney ◽  
Angela Liegey Dougall
Keyword(s):  
Mental Health ◽  
Immune System ◽  
Past Research ◽  
Delayed Wound Healing ◽  
Future Directions ◽  
The Past ◽  
Age Related ◽  
System Functioning ◽  
Increased Susceptibility

During the past few decades, research from multiple disciplines has elucidated the profound connections between the immune system and mental health. This chapter provides a review of this literature, placing emphasis on the connections between inflammation and cytokines, and stress, depression, posttraumatic stress disorder, schizophrenia, bipolar disorder, and social support. Additionally, brief overviews of the role of the natural immune system and adaptive immunity, as well as past research investigating stress are included. Further attention is focused on the physical health consequences of immune system dysregulation, ranging from increased susceptibility to infectious diseases, delayed wound healing, autoimmune responses, age-related elevations in proinflammatory cytokines, and decreased effectiveness of protective vaccinations. The chapter concludes with a discussion of the health effects and clinical implications of the relationships discussed throughout, as well as future directions to advance this field of study.

On Future Directions in Pathology

1982 ◽  
Vol 40 ◽  
pp. 274-277
Author(s):  
Benjamin F. Trump ◽  
Irene K. Berezesky ◽  
Raymond T. Jones
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Clinical Pathology ◽  
Future Directions ◽  
Diagnostic Pathology ◽  
The Past ◽  
Transmission Electron ◽  
Organ Systems ◽  
The Many

The role of electron microscopy and associated techniques is assured in diagnostic pathology. At the present time, most of the progress has been made on tissues examined by transmission electron microscopy (TEM) and correlated with light microscopy (LM) and by cytochemistry using both plastic and paraffin-embedded materials. As mentioned elsewhere in this symposium, this has revolutionized many fields of pathology including diagnostic, anatomic and clinical pathology. It began with the kidney; however, it has now been extended to most other organ systems and to tumor diagnosis in general. The results of the past few years tend to indicate the future directions and needs of this expanding field. Now, in addition to routine EM, pathologists have access to the many newly developed methods and instruments mentioned below which should aid considerably not only in diagnostic pathology but in investigative pathology as well.

scholarly journals Digital culture

2021 ◽  
Author(s):  
Alberto Acerbi
Keyword(s):  
Digital Media ◽  
Cultural Evolution ◽  
Cultural Transmission ◽  
Past Research ◽  
Digital Culture ◽  
Cultural Dynamics ◽  
Cumulative Culture ◽  
Future Directions

Cultural evolution can provide a useful framework to understand how information is produced, transmitted, and selected in contemporary online, digital, media. The diffusion of digital technologies triggered a radical departure from previous modalities of cultural transmission but, at the same time, general characteristics of human cultural evolution and cognition influence these developments. In this chapter, I will explore some areas where the links between cultural evolution research and digital media seem more promising. As cultural evolution-inspired research on internet phenomena is still in its infancy, these areas represent suggestions and links with works in other disciplines more than reviews of past research in cultural evolution. These include topics such as how to characterise the online effects of social influence and the spread of information; the possibility that digital, online, media could enhance cumulative culture; and the differences between online and offline cultural transmission. In the last section I will consider other possible future directions: the influences of different affordances in different media supporting cultural transmission; the role of producers of cultural traits; and, finally, some considerations on the effects on cultural dynamics of algorithms selecting information.

scholarly journals Role of Immunity in Pathogenesis of Psychosis

2021 ◽  
Author(s):  
Wafa Abdelghaffar ◽  
Oussama Sidhom ◽  
Lilia Laadhar ◽  
Rym Rafrafi
Keyword(s):  
Mental Health ◽  
Immune System ◽  
Psychiatric Symptoms ◽  
Scientific Evidence ◽  
Health Conditions ◽  
Future Research ◽  
Antineuronal Antibodies ◽  
System Components ◽  
The Brain

The involvement of immunity in the pathogenesis of schizophrenia and related psychoses was suspected a century ago but was shadowed by the dopaminergic hypothesis after the discovery of antipsychotics. We currently know that this latter theory has many limits and cannot account for the wide variety of psychotic conditions. The immune-inflammatory theory is now one of the most promising axes of research in terms of pathogenesis of several mental health conditions. Immunity and inflammation play a role at least in a subgroup of patients with psychosis. The immune system is complex with a variety of components and mediators that can all have effects on the brain and thus mediate psychiatric symptoms. In this chapter we will explore the scientific evidence of the role of immune system in pathophysiology of psychosis. The sections of this chapter will discuss the role of innate system components (cytokines, microglia, inflammation.), the role of adaptive system (lymphocytes and antibodies) with a section focusing on auto-immunity and particularly antineuronal antibodies. Finally we will discuss how this research can impact patients management and elaborate recommendations for future research.

Restaurant and foodservice research

2017 ◽  
Vol 29 (4) ◽  
pp. 1203-1234 ◽  
Author(s):  
Robin DiPietro
Keyword(s):  
Past Research ◽  
Future Research ◽  
Research Papers ◽  
Content Type ◽  
The Past ◽  
Restaurant Management ◽  
Foodservice Industry ◽  
Future Direction

Purpose The purpose of this paper is to present a review of the foodservice and restaurant literature that has been published over the past 10 years in the top hospitality and tourism journals. This information will be used to identify the key trends and topics studied over the past decade, and help to identify the gaps that appear in the research to identify opportunities for advancing future research in the area of foodservice and restaurant management. Design/methodology/approach This paper takes the form of a critical review of the extant literature that has been done in the foodservice and restaurant industries. Literature from the past 10 years will be qualitatively assessed to determine trends and gaps in the research to help guide the direction for future research. Findings The findings show that the past 10 years have seen an increase in the number of and the quality of foodservice and restaurant management research articles. The topics have been diverse and the findings have explored the changing and evolving segments of the foodservice industry, restaurant operations, service quality in foodservice, restaurant finance, foodservice marketing, food safety and healthfulness and the increased role of technology in the industry. Research limitations/implications Given the number of research papers done over the past 10 years in the area of foodservice, it is possible that some research has been missed and that some specific topics within the breadth and depth of the foodservice industry could have lacked sufficient coverage in this one paper. The implications from this paper are that it can be used to inform academics and practitioners where there is room for more research, it could provide ideas for more in-depth discussion of a specific topic and it is a detailed start into assessing the research done of late. Originality/value This paper helps foodservice researchers in determining where past research has gone and gives future direction for meaningful research to be done in the foodservice area moving forward to inform academicians and practitioners in the industry.

Women in the history of linguistics

2020 ◽  
pp. 1-30
Author(s):  
Wendy Ayres-Bennett ◽  
Helena Sanson
Keyword(s):  
Language Acquisition ◽  
Central Section ◽  
Future Directions ◽  
The Past ◽  
Early Stages ◽  
Challenges And Opportunities ◽  
History Of Linguistics ◽  
History Of ◽  
Role Of Women

This Introduction outlines the need for a ‘true history’ (Lerner 1976) of the role of women in the history of linguistics, which considers them on their own terms, and challenges categories and concepts devised for traditional male-dominated accounts. We start by considering what research has already been conducted in the field, before exploring some of the reasons for the relative dearth of studies. We outline some of the challenges and opportunities encountered by women who wished to study the nature of language and languages in the past. The geographical and chronological scope of this volume is then discussed. In a central section we examine some of the major recurring themes in the volume. These include attitudes towards women’s language, both positive and negative; women and language acquisition and teaching; and women as creators of new languages and scripts. We further explore women as authors, dedicatees, or intended readers of metalinguistic texts, as interpreters and translators, and as contributors to the linguistic documentation and maintenance. We consider how women supported male relatives and colleagues in their endeavours, sometimes in invisible ways, before reviewing the early stages of their entry into institutionalized contexts. The chapter concludes with a brief section on future directions for research.

A survey of instrumented indentation studies on metallic glasses

2004 ◽  
Vol 19 (1) ◽  
pp. 46-57 ◽  
Author(s):  
C.A. Schuh ◽  
T.G. Nieh
Keyword(s):  
Metallic Glasses ◽  
Structural Changes ◽  
Shear Banding ◽  
Depth Sensing ◽  
Future Directions ◽  
Fundamental Physics ◽  
New Approach ◽  
The Past ◽  
Rate Dependent

The development of instrumented nanoindentation equipment has occurred concurrently with the discovery of many new families of bulk metallic glass during the past decade. While indentation testing has long been used to assess the mechanical properties of metallic glasses, depth-sensing capabilities offer a new approach to study the fundamental physics behind glass deformation. This article is a succinct review of the research to date on the indentation of metallic glasses. In addition to standard hardness measurements, the onset of plasticity in metallic glasses is reviewed as well as the role of shear banding in indentation, structural changes beneath the indenter, and rate-dependent effects measured by nanoindentation. The article concludes with perspectives about the future directions for nanocontact studies on metallic glasses.

Introduction

2020 ◽  
pp. 1-6
Author(s):  
Alisoun Milne
Keyword(s):  
Mental Health ◽  
Mental Illness ◽  
Health Outcomes ◽  
Later Life ◽  
Social Categories ◽  
Age Related ◽  
Wide Range ◽  
Life Itself ◽  
Life Course Analysis

Despite much emphasis on mental illness in later life, limited work has focused on mental health. This book aims to address this deficit by exploring, and explaining, mental health outcomes in later life through the lens of critical social gerontology and via the conduit of life course analysis. It adopts an approach underpinned by a commitment to understanding, and making visible, the role of lifecourse, and age related inequalities in creating or amplifying risks to mental health, as well as exploring those issues that afford protection. It aims to offer a critical review of existing discourse and disrupt the ‘taken for granted’ paradigm, including in the dementia arena. This approach not only recognises that mental health in later life is a complex multi-dimensional issue that cuts across time, cohort, social categories and individual experiences but that it is affected by a wide range of lifecourse and age related issues. It also encourages the development of understanding that adopts a wide lens of analysis and of policy and service related responses that reduce risks to mental health during the lifecourse and in later life itself. Further, it engages with the potential to learn from older people’s perspectives and lives.

scholarly journals Role of Autophagy and Apoptosis in the Postinfluenza Bacterial Pneumonia

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Zhen Qin ◽  
Yuan Yang ◽  
Hongren Wang ◽  
Jun Luo ◽  
Xiaojun Huang ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Influenza A Virus ◽  
Bacterial Pneumonia ◽  
Influenza A ◽  
Bacterial Infections ◽  
Research Progress ◽  
The Past ◽  
Recent Research Progress ◽  
Increased Susceptibility

The risk of influenza A virus (IAV) is more likely caused by secondary bacterial infections. During the past decades, a great amount of studies have been conducted on increased morbidity from secondary bacterial infections following influenza and provide an increasing number of explanations for the mechanisms underlying the infections. In this paper, we first review the recent research progress that IAV infection increased susceptibility to bacterial infection. We then propose an assumption that autophagy and apoptosis manipulation are beneficial to antagonize post-IAV bacterial infection and discuss the clinical significance.

Effects of External Loading on the Morphology of the Yielded Regions in Trabecular Bone Predicted by FEA

2008 ◽  
Author(s):  
Xiutao Shi ◽  
Xiang Wang ◽  
Glen L. Niebur
Keyword(s):  
Trabecular Bone ◽  
High Stress ◽  
Tissue Level ◽  
External Loading ◽  
Trabecular Architecture ◽  
Mineral Density ◽  
Age Related ◽  
Insight Into ◽  
Increased Susceptibility

Osteoporosis is an age-related skeletal condition characterized by low bone mineral density and deterioration of the trabecular architecture leading to increased susceptibility to fracture [1]. Wolff hypothesized that trabecular architecture adapts to have its principal material axes aligned with the principal loading directions. Regions of experimentally labeled trabecular microdamage correspond to areas of high stress and strain calculated from FEA [2]. Studying the morphology of numerically predicted regions of tissue level yielding might provide insight into the role of trabecular architecture in the strength of trabecular bone.

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