Spatially Dispersed Ties Among Interdependent Citizens: Connecting Individuals and Aggregates

2002 ◽  
Vol 10 (3) ◽  
pp. 261-275 ◽  
Author(s):  
Brady Baybeck ◽  
Robert Huckfeldt

A continuing tradition in contextual analysis locates individual citizens within spatially defined, aggregate settings in an effort to provide a more complete account of individual behavior. Given the increasing individual mobility within society, it is less than clear that geography continues to define the boundaries on meaningful aggregate contexts—people have become less tied to their geographic contexts, and technology makes it possible for citizens to maintain relationships independently of space, distance, and location. In this paper we pursue an analysis and set of analytic techniques that are designed to connect individual voters, their communication networks, and the geography that surrounds them. The analytic techniques utilize a unique data set that captures spatial dispersion in an individual's social and political network, and from these analyses we can draw two conclusions. First, spatial dispersion in a network does have an effect on interaction within the network; the world is not full of voters who operate independently of their geographic contexts. Second, spatial dispersion provides opportunities to connect citizens living in different geographic contexts, thereby creating bridges for communication across different contexts. These findings suggest that scholars might profitably incorporate geography as an important component of the complex relationships among and between individual citizens in explaining the role of the individual in modern democratic politics.

Author(s):  
Asri Sulistiawati

This study aims to: (1) identify the structure of communication within the gapoktan and farmer gropus, (2) identify the role of the individual in the communication structure This study is quantitative research support by qualitative data. This study is descriptive correlational  with the analysis unit consisting of individual analysis units totaling 102 people, as well as the unit of analysis group consisting of four groups of farmers who are members of the Gapoktan in the Laladon Village, Ciomas subdistrict, Bogor regency. For identifying the communication networks, this study use UCINET VI software. The result showed that the density of group depend on the numbers of member in the group. KWT Sejahtera is one of the group which is has highest centrality and the Mandiri II farmer group has the lowest centrality because this group has many isolate members.Keywords: centralization, communication network, farmer group---------------------------- ABSTRAKPenelitian ini bertujuan untuk mengidentifikasi struktur komunikasi antar anggota kelompok tani yang tergabung dalam gabungan kelompok tani (gapoktan) Tani Berkah. Lebih lanjut, penelitian ini juga bertujuan untuk mengidentifikasi peranan individu di dalam jaringan komunikasi kelompok tani. Penelitian ini merupakan penelitian kuantitatif melalui metode sensus dengan jumlah keseluruhan responden sebanyak 102 orang yang terdistribusi ke dalam empat kelompok tani. Dalam menganalisis jaringa komunikasi, penelitian ini menggunakan analisis sosiometri melalui perangkat UCINET VI. Penelitian ini menunjukkan bahwa tingkat kepadatan dalam jaringan komunikasi kelompok bergantung pada jumlah anggota kelompok itu sendiri. Adapun Kelompok Wanita Tani Sejahtera merupakan kelompok dengan derajat sentralitas paling tinggi yang ditunjukkan dengan diagram sosiometri yang paling memusat dan paling sedikit memiliki anggota yang menjadi isolate.Kata Kunci: jaringan, sentralisasi, sosiometri


2015 ◽  
Vol 291 (4) ◽  
pp. 1582-1590
Author(s):  
Sabine C. Mueller ◽  
Björn Sommer ◽  
Christina Backes ◽  
Jan Haas ◽  
Benjamin Meder ◽  
...  

Understanding the role of genetics in disease has become a central part of medical research. Non-synonymous single nucleotide variants (nsSNVs) in coding regions of human genes frequently lead to pathological phenotypes. Beyond single variations, the individual combination of nsSNVs may add to pathogenic processes. We developed a multiscale pipeline to systematically analyze the existence of quantitative effects of multiple nsSNVs and gene combinations in single individuals on pathogenicity. Based on this pipeline, we detected in a data set of 842 nsSNVs discovered in 76 genes related to cardiomyopathies, associated nsSNV combinations in seven genes present in at least 70% of all 639 patient samples, but not in a control cohort of healthy humans. Structural analyses of these revealed primarily an influence on the protein stability. For amino acid substitutions located at the protein surface, we generally observed a proximity to putative binding pockets. To computationally analyze cumulative effects and their impact, pathogenicity methods are currently being developed. Our approach supports this process, as shown on the example of a cardiac phenotype but can be likewise applied to other diseases such as cancer.


2021 ◽  
Author(s):  
Antonio Galiana ◽  
Javier García-Abellán ◽  
Marta Fernández-González ◽  
Nieves Gonzalo-Jiménez ◽  
Montserrat Ruiz-García ◽  
...  

Abstract Background: Differentiating between persistent infection with intermittent viral shedding and reinfection with SARS-CoV-2 remains challenging. Although a small number of cases with genomic evidence of second infection have been reported, limited information exists on frequency and determinants of reinfection, time between infections, and duration of immunity after the primary infection. Case presentation: We report a reinfection with SARS-CoV-2 in a 52-year old male whose primary infection was diagnosed in May 2020, during the first wave of the pandemic in Spain, and the second occurred eight months later, in January 2021. We present a complete data set including results from real-time polymerase chain reaction, serology and genome sequencing confirming reinfection with a different clade. Noteworthy was that the patient was immunocompetent but had multiple cardiometabolic comorbidities, including refractory arterial hypertension, that might increase the individual risk in COVID-19.Conclusions: This case of reinfection with SARS CoV-2 occurring several months after the primary infection reports the longest time interval between reinfection and initial infection described to date. It raises concerns on the duration of protective immunity, suggesting that it may begin to wane in patients who acquired the initial infection during the first wave of the pandemic. The potential contributing role of arterial hypertension and cardiometabolic comorbidities as risk factors for reinfection deserves investigation.


2017 ◽  
Vol 38 (5) ◽  
pp. 765-787 ◽  
Author(s):  
Yolanda F. Rebollo-Sanz

Purpose The purpose of this paper is to show that for some key topics on labour economics such as the effect of seniority and job mobility in wages, it is important to explicitly consider firm fixed effects. The author also wants to test whether the importance of firm in explaining wage dispersion is higher or lower in Spain than in other European countries. Design/methodology/approach The author estimates an individual wage equation where firm and workers effects are considered and the estimation process control for censored wages. This exercise is performed for the Spanish economy over the course of a whole business cycle, i.e., 2000-2015. Findings The author demonstrates that Spanish firms contribute to explain around 27 per cent of the individual wage heterogeneity but more importantly around 74 per cent of inter-industry wage differentials. In both cases, this contribution is mainly related to large dispersion in firm’s wage policies. The process of positive sorting of workers across firms or industries does not play an important role. Interestingly, the importance of firm’s wage policies in explaining individual wage dispersion has increased over the current Big Recession. Practical implications The results confirm that firms set wages and, henceforth, are partially responsible for individual wage heterogeneity but more importantly for inter-industrial wage dispersion. Originality/value The exercise is performed under optimal conditions because the author uses a longitudinal matched employer-employee data set, observed wages are at a monthly frequency, and implements an estimation method suitable for censored models with two high-dimensional fixed effects. This is the first study that looks deeply into the role of firms in explaining wage heterogeneity at the individual and industry level in Spain and along the current Big Recession.


Author(s):  
Miguel Torres Preto ◽  
Tiago Farlens

Creativity as source of growth and development has been target of increase interest by several authors. Using a matched employer-employee data set called Quadros de Pessoal, containing information regarding Portuguese private firms and their employees; this paper aims to shed light about the role of creative workers in Portugal. Empirical findings suggest that creative workers have higher educational levels and also higher salaries, and that they are mostly present in smaller, older multinational firms. Moreover, creative workers have a higher propensity to become entrepreneurs compared to non-creative workers, even considering the individual characteristics such as education and firm's characteristics. This paper applies concepts and methodologies used previously in national and international studies and aims to establish a solid foundation, with empirical data for future research related to the themes of creativity, entrepreneurship and work.


Author(s):  
Rosario Forlenza

This chapter analyzes the liminal time of the war as a critical interstice of creative pluralism, and explores the various meanings of democracy that emerged from the transformative experiences of Italians in the years 1943–5. The chapter criticizes the rationalist approaches that distinguish between beginning and end, between clear-cut positions either in terms of party allegiance, institutional affiliation, or ideological commitment. It examines the argument for what had been called the “grey zone” of the fluid, unfinished, chaotic, and bewildering. Furthermore, it explores the strategies of resistance formulated by subordinate groups, the very important case of the role of women, and the heightened sense of social equality that developed during and despite the war. It makes the case for the foundation of democratic politics in the individual and collective experiences of undergoing social dramas and being forced to make political and existential choices.


Author(s):  
D. E. Becker

An efficient, robust, and widely-applicable technique is presented for computational synthesis of high-resolution, wide-area images of a specimen from a series of overlapping partial views. This technique can also be used to combine the results of various forms of image analysis, such as segmentation, automated cell counting, deblurring, and neuron tracing, to generate representations that are equivalent to processing the large wide-area image, rather than the individual partial views. This can be a first step towards quantitation of the higher-level tissue architecture. The computational approach overcomes mechanical limitations, such as hysterisis and backlash, of microscope stages. It also automates a procedure that is currently done manually. One application is the high-resolution visualization and/or quantitation of large batches of specimens that are much wider than the field of view of the microscope.The automated montage synthesis begins by computing a concise set of landmark points for each partial view. The type of landmarks used can vary greatly depending on the images of interest. In many cases, image analysis performed on each data set can provide useful landmarks. Even when no such “natural” landmarks are available, image processing can often provide useful landmarks.


2013 ◽  
Vol 18 (2) ◽  
pp. 126-135 ◽  
Author(s):  
Frosso Motti-Stefanidi ◽  
Ann S. Masten

Academic achievement in immigrant children and adolescents is an indicator of current and future adaptive success. Since the future of immigrant youths is inextricably linked to that of the receiving society, the success of their trajectory through school becomes a high stakes issue both for the individual and society. The present article focuses on school success in immigrant children and adolescents, and the role of school engagement in accounting for individual and group differences in academic achievement from the perspective of a multilevel integrative model of immigrant youths’ adaptation ( Motti-Stefanidi, Berry, Chryssochoou, Sam, & Phinney, 2012 ). Drawing on this conceptual framework, school success is examined in developmental and acculturative context, taking into account multiple levels of analysis. Findings suggest that for both immigrant and nonimmigrant youths the relationship between school engagement and school success is bidirectional, each influencing over time the other. Evidence regarding potential moderating and mediating roles of school engagement for the academic success of immigrant youths also is evaluated.


Acta Naturae ◽  
2016 ◽  
Vol 8 (2) ◽  
pp. 79-86 ◽  
Author(s):  
P. V. Elizar’ev ◽  
D. V. Lomaev ◽  
D. A. Chetverina ◽  
P. G. Georgiev ◽  
M. M. Erokhin

Maintenance of the individual patterns of gene expression in different cell types is required for the differentiation and development of multicellular organisms. Expression of many genes is controlled by Polycomb (PcG) and Trithorax (TrxG) group proteins that act through association with chromatin. PcG/TrxG are assembled on the DNA sequences termed PREs (Polycomb Response Elements), the activity of which can be modulated and switched from repression to activation. In this study, we analyzed the influence of transcriptional read-through on PRE activity switch mediated by the yeast activator GAL4. We show that a transcription terminator inserted between the promoter and PRE doesnt prevent switching of PRE activity from repression to activation. We demonstrate that, independently of PRE orientation, high levels of transcription fail to dislodge PcG/TrxG proteins from PRE in the absence of a terminator. Thus, transcription is not the main factor required for PRE activity switch.


2019 ◽  
pp. 22-29
Author(s):  
Н. В. Фрадкіна

The purpose and tasks of the work are to analyze the contemporary Ukrainian mass culture in terms of its value and humanistic components, as well as the importance of cultural studies and Ukrainian studies in educational disciplines for the formation of a holistic worldview of modern youth.Analysis of research and publications. Scientists repeatedly turned to the problems of the role of spirituality in the formation of society and its culture. This problem is highlighted in the publications by O. Losev, V. Lytvyn, D. Likhachev, S. Avierintsev, M. Zakovych, I. Stepanenko and E. Kostyshyn.Experts see the main negative impact of mass culture on the quality approach, which determines mass culture through the market, because mass culture, from our point of view, is everything that is sold and used in mass demand.One of the most interesting studies on this issue was the work by the representatives of Frankfurt School M. Horkheimer and T. Adorno «Dialectics of Enlightenment» (1947), devoted to a detailed analysis of mass culture. Propaganda at all socio-cultural levels in the form is similar in both totalitarian and democratic countries. It is connected, according to the authors, with the direction of European enlightenment. The tendency to unify people is a manifestation of the influence of mass culture, from cinema to pop. Mass culture is a phenomenon whose existence is associated with commerce (accumulation in any form – this is the main feature of education), in general, the fact that it exists in this form is related to the direction of the history of civilization.Modern mass culture, with its externally attractive and easily assimilated ideas and symbols, appealing to the trends of modern fashion, becomes a standard of prestigious consumption, does not require intense reflection, allows you to relax, distract, not teach, but entertains, preaches hedonism as the main spiritual value. And as a consequence, there are socio-cultural risks: an active rejection of other people, which leads to the formation of indifference; cruelty as a character trait; increase of violent and mercenary crime; increase in the number of alcohol and drug addicts; anti-patriotism; indifference to the values of the family and as a result of social orphanhood and prostitution.Conclusions, perspectives of research. Thus, we can conclude that modern Ukrainian education is predominantly formed by the values of mass culture. Namely, according to the «Dialectic» by Horkheimer and Adorno, «semi-enlightenment becomes an objective spirit» of our modern society.It is concluded that only high-quality education can create the opposite of the onset of mass culture and the destruction of spirituality in our society. It is proved that only by realizing the importance of cultivating disciplines in the educational process and the spiritual upbringing of the nation, through educational reforms, humanitarian knowledge will gradually return to student audiences.Formation of youth occurs under the influence of social environment, culture, education and self-education. The optimal combination of these factors determines both the process of socialization itself and how successful it will be. In this context, one can see the leading role of education and upbringing. It turns out that the main task of modern education is to spread its influence on the development of spiritual culture of the individual, which eventually becomes a solid foundation for the formation of the individual. Such a subject requires both philosophical and humanitarian approaches in further integrated interdisciplinary research, since the availability of such research will provide the theoretical foundation for truly modern educational and personal development.


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