scholarly journals Estimating the proportion of coronavirus disease 2019 (COVID-19) cases among households in France: a cross-sectional study based on individuals with myocardial infarction history

2020 ◽  
Author(s):  
Laurie Fraticelli ◽  
Julie Freyssenge ◽  
Clément Claustre ◽  
Mikaël Martinez ◽  
Abdesslam Redjaline ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Telephone Survey ◽  
Cross Sectional Study ◽  
Severe Form ◽  
Infection Rates ◽  
Cross Sectional ◽  
The Past ◽  
Health Measures ◽  
Increased Risk ◽  
All Cause Mortality

AbstractBackgroundPrevious studies have identified that adults with cardiovascular diseases were disproportionately associated with a significantly increased risk of a severe form of COVID-19 and all-cause mortality. We aimed to describe the diagnosed COVID-19 cases and to estimate the symptomatic and asymptomatic suspected cases among individuals with pre-existing myocardial infarction myocardial infarction and their relatives in lockdown period. Methods: We conducted a two-week cross-sectional telephone survey, from May 4 to May 15, 2020, including all households with at least one individual with pre-existing cardiovascular disease in the past two years. We defined a suspected COVID-19 case when living with at least one individual tested positive to COVID-19, or when an individual has been in contact with a suspected or confirmed case since the March 1rst, or when a relative from the same house has been hospitalized or deceased for COVID-19.ResultsWe observed high rates of compliance with health measures during the lockdown period, regardless of age or risk factors. Among individuals with myocardial infarction history, two were COVID-19 confirmed, 13·37% were suspected (94/703) of whom 70·21% (66/94) asymptomatic.ConclusionsIndividuals with myocardial infarction history presented different symptoms association with more respiratory signs. This population, which is older and associated with more comorbidities, is exposed to a high risk of complication in the event of contamination. Infection rates are relevant to adjusting the management of emergency departments in our region.

scholarly journals Estimating the Proportion of Coronavirus Disease 2019 Contacts Among Households based on Individuals with Myocardial Infarction History: a cross-sectional telephone survey (Preprint)

2021 ◽  
Author(s):  
Laurie Fraticelli ◽  
Julie Freyssenge ◽  
Clément Claustre ◽  
Mikaël Martinez ◽  
Abdesslam Redjaline ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Telephone Survey ◽  
Severe Form ◽  
Cross Sectional ◽  
The Past ◽  
Health Measures ◽  
Increased Risk ◽  
All Cause Mortality ◽  
Associated Symptoms ◽  
Limited Period

UNSTRUCTURED Adults with cardiovascular diseases were disproportionately associated with a significantly increased risk of a severe form of COVID-19 and all-cause mortality. We aimed to report the associated symptoms for COVID-19 cases, and to estimate the proportion of contacts. We conducted a two-week cross-sectional telephone survey during the first lock-down period in France, including all households with at least one individual with pre-existing cardiovascular disease in the past two years. We observed high rates of compliance with health measures, regardless of age or risk factors. Four COVID-19 cases were reported from four different households. We estimated that 9.73% were contacts of whom 71.52% were asymptomatic. Among individuals with myocardial infarction history, two were COVID-19 cases. We estimated that 8.68% were contacts of whom 68.85% were asymptomatic. The cases and contacts presented different symptoms, with more respiratory signs. The telephone survey could be a relevant tool for reporting the number of contacts on a limited period and area, based on the presence of associated symptoms and COVID-19 cases in the households. This study advanced our knowledge to better prepare for future crises.

scholarly journals Colchicine Use Is Associated with Decreased Prevalence of Myocardial Infarction in Patients with Gout

2012 ◽  
Vol 39 (7) ◽  
pp. 1458-1464 ◽  
Author(s):  
DARIA B. CRITTENDEN ◽  
R. AARON LEHMANN ◽  
LAURA SCHNECK ◽  
ROBERT T. KEENAN ◽  
BINITA SHAH ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
New York ◽  
Statistical Significance ◽  
International Classification Of Diseases ◽  
Serum Urate ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
All Cause Mortality ◽  
Classification Of Diseases ◽  
Level Versus

Objective.The ability of antiinflammatory strategies to alter cardiovascular risk has not been rigorously examined. Colchicine is an antiinflammatory agent that affects macrophages, neutrophils, and endothelial cells, all of which are implicated in the pathogenesis of cardiovascular disease. We examined whether colchicine use was associated with a reduced risk of myocardial infarction (MI) in patients with gout.Methods.We conducted a retrospective, cross-sectional study of all patients with an International Classification of Diseases, 9th ed, code for gout in the electronic medical record (EMR) of the New York Harbor Healthcare System Veterans Affairs network and ≥ 1 hospital visit between August 2007 and August 2008. Hospital pharmacy data were used to identify patients who had filled at least 1 colchicine prescription versus those who had not. Demographics and CV comorbidities were collected by EMR review. The primary outcome was diagnosis of MI. Secondary outcomes included all-cause mortality and C-reactive protein (CRP) level.Results.In total, 1288 gout patients were identified. Colchicine (n = 576) and no colchicine (n = 712) groups had similar baseline demographics and serum urate levels. Prevalence of MI was 1.2% in the colchicine versus 2.6% in the no-colchicine group (p = 0.03). Colchicine users also had fewer deaths and lower CRP levels, although these did not achieve statistical significance. Colchicine effects persisted when allopurinol users were excluded from the analysis.Conclusion.In this hypothesis-generating study, gout patients who took colchicine had a significantly lower prevalence of MI and exhibited trends toward reduced all-cause mortality and lower CRP level versus those who did not take colchicine.

scholarly journals Risk of anaemia among women engaged in biomass-based fish smoking as their primary livelihood in the central region of Ghana: a comparative cross-sectional study

BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Daniel Armo-Annor ◽  
Esi K. Colecraft ◽  
Seth Adu-Afarwuah ◽  
Aaron Kobina Christian ◽  
Andrew D. Jones
Keyword(s):  
Central Region ◽  
Cross Sectional Study ◽  
Total Iron ◽  
Biomass Fuel ◽  
Dietary Iron ◽  
Iron Intake ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Past ◽  
Increased Risk

Abstract Background Fish smoking using biomass fuel is an important livelihood for women living in the coastal regions of Ghana and may contribute to anaemia risk. We assessed whether women who smoke fish as their primary livelihood are at increased risk of anaemia compared to women in other livelihoods in the Central Region of Ghana. Methods We conducted a comparative cross-sectional study of 330 randomly selected adult women (18–49 years) whose primary livelihood was either fish smoking (FSL) involving the burning of biomass fuel (n = 175) or other livelihoods (OL) not involving burning of firewood (n = 155). Data on participants’ recent diet were collected from a single, quantitative 24-h dietary recall and qualitative 7-day food frequency questionnaire of animal-source food (ASF) consumption. We further assessed participants’ haemoglobin concentration using the Urit 12 Hemocue system. We compared total iron intakes, the proportion of dietary iron from animal and plant sources, mean haemoglobin concentrations, and anaemia prevalence between FSL and OL women. Results Fish was the most frequently consumed ASF by both groups of women. Although OL women consumed more diverse ASFs in the past week compared with the FSL women (3.4 ± 1.2 vs. 2.7 ± 1.3; p < 0.001), the contribution of ASFs to total iron intake in the past day was greater for the FSL women (49.5% vs. 44.0%; p = 0.030). Estimated total dietary iron intake in the past day was generally low (5.2 ± 4.7 mg) and did not differ by group. The unadjusted prevalence of anaemia was 32 and 27.1% among the FSL and OL women, respectively (p = 0.33). After covariates adjustment, the FSL women had statistically higher anaemia prevalence (36.4% vs. 20.5%; p = 0.032) and 80% greater risk of being anemic (RR: 1.8; 95% CI: 1.1, 3.0) than the OL women. Conclusion Women who use biomass fuel to smoke fish as their primary livelihood had an increased risk of anaemia. Furthermore, the average 24-h dietary iron intake among both the FSL and OL women was below their daily iron requirement. Interventions to enhance women’s dietary iron intake and reduce their livelihood related biomass smoke exposure may be warranted in this population.

P3624Prevalence and severity of coronary artery disease linked to prognosis in psoriasis patients referred for coronary computed tomography angiography: A multicentre cohort study

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A B Tinggaard ◽  
K F Hjuler ◽  
I T Andersen ◽  
S Winther ◽  
L Iversen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Follow Up Study ◽  
Increased Risk ◽  
All Cause Mortality ◽  
Artery Disease

Abstract Background Psoriasis (Pso) is a disease characterized by systemic inflammation and is associated with an increased risk of cardiovascular disease. However, the degree of coronary artery calcification in Pso and its relation to prognosis is largely unknown. Purpose The aim of this study was 1) to estimate the prevalence and severity of coronary artery disease (CAD) in this patient group and 2) to asses the risk of major adverse cardiovascular events (MACE) including revascularization and all-cause mortality after initial diagnosis and treatment in a large-scale cohort of patients who underwent coronary computed tomography angiography (CCTA) due to angina symptoms. Methods This study consists of two parts using data from the Western Denmark Heart Registry; a cross-sectional study included 40,125 patients and a follow-up study included 42,861 patients. Pso patients were identified by the National Patient Registry and verified by nationwide prescription and treatment code registers. Primary outcome in the cross-sectional study was a coronary artery calcium score (CACS) >0, with a secondary outcome defined as a CACS ≥400. In the follow-up study, the primary outcome was a combined outcome including myocardial infarction, revascularization, ischemic or unspecified stroke and all-cause mortality. Events within the first 90 days after CCTA were attributed to initial treatment and consequently excluded. All outcomes were adjusted for common cardiovascular risk factors and comorbidities. Results In the cross-sectional study 1,407 (3.5%) Pso patients were identified. OR was 1.31 (95% CI; 1.15–1.49) for CACS >0 and 1.33 (95% CI; 1.10–1.62) for CACS ≥400 in Pso patients compared to non-Pso patients. In the follow-up study 1,591 (3.7%) Pso patients were identified. The mean duration of follow-up after CCTA was 4.0 years (min/max 0.0/10.2). Crude HR for the combined outcome was 1.52 (95% CI; 1.24–1.87), while adjusted HR was 1.16 (95% CI; 0.95–1.43). Conclusion In this clinically relevant cohort of patients referred to CCTA for CAD rule out, coronary artery calcification was more frequent and more severe in Pso patients even compared to the control patients with several risk factors and angina symptoms, but without inflammatory diseases. An increased risk of the combined outcome of MACE including revascularization and all-cause mortality after initial treatment in Pso patients was found in the crude analysis. The increased risk seemed predominantly carried by an increase in traditional risk factors.

scholarly journals Association between ESR2 Genetic Variants and Risk of Myocardial Infarction

2008 ◽  
Vol 54 (7) ◽  
pp. 1183-1189 ◽  
Author(s):  
Sophie Domingues-Montanari ◽  
Isaac Subirana ◽  
Marta Tomás ◽  
Jaume Marrugat ◽  
Mariano Sentí
Keyword(s):  
Myocardial Infarction ◽  
Cardiac Risk ◽  
Cross Sectional Study ◽  
Dependent Manner ◽  
Nucleotide Polymorphisms ◽  
Cross Sectional ◽  
Single Nucleotide ◽  
Increased Risk ◽  
Nested Case Control ◽  
Esr2 Gene

Abstract Background: Environmental and genetic factors contribute to the development of complex diseases such as myocardial infarction (MI), the leading cause of death in men and women. Women develop MI approximately 10 years later than men, a difference that could be explained by the genes coding for the estrogen receptors. Single nucleotide polymorphisms (SNPs) in the ESR2 gene may affect susceptibility for MI in a sex-dependent manner. Methods: A nested case-control design was used to analyze 3 polymorphisms of the ESR2 gene and their associated haplotypes in 710 myocardial infarction cases from the REGICOR (Registre Gironí del Corazón) study and 2379 controls randomly selected in a representative population of a Spanish cross-sectional study. Results: The rs1271572 T allele was significantly more common in patients who developed MI (P &lt; 0.001). No association was observed for rs1256049 or rs4986938. Assuming a dominant model of inheritance, the association, as determined by logistic multivariate regression after adjustment for conventional cardiac risk factors, remained statistically significant in men [odds ratio (OR) 1.65, 95% CI 1.18–2.30; P = 0.003) but not in women (P = 0.754). A very common haplotype encompassing the rs1271572 variant was also associated with the risk of MI in the overall population (OR 1.41, 95% CI 1.06–1.87; P = 0.020) and in men (OR 1.57, 95% CI 1.12–2.21; P = 0.009). Conclusions: The rs1271572 SNP T variant was associated with increased risk of MI in a Spanish population, and this association was found to be limited to men only. Sex differences in the genetic risk merit further investigation.

scholarly journals Association of Level of Physical Exertion with Acute Myocardial Infarction in Bangladeshi Population

2016 ◽  
Vol 8 (2) ◽  
pp. 115-122
Author(s):  
Md Kamrul Azad ◽  
Abdul Wadud Chowdhury ◽  
Mohammad Arifur Rahman ◽  
Shohael M Arafat ◽  
Sheikh Foyez Ahmed ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Physical Exertion ◽  
Cross Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Metabolic Equivalents ◽  
Increased Risk ◽  
History Of ◽  
Bangladeshi Population

Background: Evidences suggest that heavy physical exertion can trigger the onset of acute myocardial infarction. But there have been no clean cut data in Bangladesh about the risk of myocardial infarction during and after heavy exertion. To address this question the study was conducted.Methods: It was a multicentre cross sectional study was conducted from July 2012 to June 2013 with patient of diagnosed acute myocardial infarction (AMI) admitted in department of cardiology of National Institute of Cardiovascular Diseases (NICVD), Bangabandhu Sheikh Mujib Medical University (BSMMU) and Dhaka Medical College Hospital (DMCH). From selected samples, two hours activity prior to onset of symptom of AMI was asked according to standard questionnaire. Activities were quantified on a scale from 1 to 8 metabolic equivalents (METs) according to generally accepted values. Collected data were analyzed by SPSS version 16.Results: In this study 246 patients (74 .4 percent of whom were men; mean age [±SD], 64.68 ± 7.63 years) were interviewed. The study showed that 11.38% patients were engaged in strenuous physical exertion (e” 6 METs) within two hours prior to symptom onset of AMI. Strenuous exertion group of AMI patients were all most all sedentary worker [26 (92.86%) of 28]. Most of the patients (82.14 %) of strenuous group had history of less than 8 hours work per day. Strenuous exertion group had history of longtime exertion (72.57%, 1-2 hours) than non-strenuous group (42.66%, <0.5 hours). Moreover, 67.86% AMI patients of strenuous exertion group had experienced irregular exertion whereas most of the patients (64.22%) of non strenuous group had a history of regular exertion.Conclusions: The result of the study indicates that a period of strenuous physical activity is associated with increased risk of having AMI, particularly among patients of sedentary worker who have dyslipidemia and who exercise irregularly. Those who exercise regularly have lower chances of AMI as shown by the negative correlation.Cardiovasc. j. 2016; 8(2): 115-122

Suicidal Ideation Among Medical Students in Dammam, Saudi Arabia

Crisis ◽  
2020 ◽  
pp. 1-6
Author(s):  
Mohammed Madadin ◽  
Ritesh G. Menezes ◽  
Maha A. Alassaf ◽  
Abdulaziz M. Almulhim ◽  
Mahdi S. Abumadini ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Medical Students ◽  
Suicidal Ideation ◽  
General Health Questionnaire ◽  
Cross Sectional Study ◽  
Eastern Province ◽  
Cross Sectional ◽  
The Past ◽  
Depression Subscale ◽  
History Of

Abstract. Background: Medical students are at high risk of suicidal ideation. Aim: We aimed to obtain information on suicidal ideation among medical students in Dammam located in the Eastern Province of Saudi Arabia. Method: This cross-sectional study was conducted at the College of Medicine affiliated with Imam Abdulrahman Bin Faisal University in the Eastern Province of Saudi Arabia. Suicidal ideation in the past 12 months was assessed based on responses to four questions in the depression subscale of the General Health Questionnaire 28 (GHQ-28). In addition, data were collected to examine the association of suicidal ideation with various factors. Results: We found that 1 in 3 medical students in the study had suicidal ideation in the past 12 months, while around 40% had lifetime suicidal ideation. Suicidal ideation was associated with feelings of parental neglect, history of physical abuse, and dissatisfaction with academic performance. Limitations: The cross-sectional nature of this study limits its ability to determine causality regarding suicidal ideation. Conclusion: These rates are considerably high when compared with rates from studies in other countries around the world. This study provides a reference in the field of suicidology for this region of Saudi Arabia.

scholarly journals SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study

Thorax ◽  
2020 ◽  
Vol 75 (12) ◽  
pp. 1089-1094 ◽  
Author(s):  
Adrian Shields ◽  
Sian E Faustini ◽  
Marisol Perez-Toledo ◽  
Sian Jossi ◽  
Erin Aldera ◽  
...  
Keyword(s):  
Intensive Care ◽  
Healthcare Workers ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Nasopharyngeal Swab ◽  
Sectional Study ◽  
University Hospitals ◽  
Cross Sectional ◽  
General Internal ◽  
Increased Risk

ObjectiveTo determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers.DesignA cross-sectional study of asymptomatic healthcare workers undertaken on 24/25 April 2020.SettingUniversity Hospitals Birmingham NHS Foundation Trust (UHBFT), UK.Participants545 asymptomatic healthcare workers were recruited while at work. Participants were invited to participate via the UHBFT social media. Exclusion criteria included current symptoms consistent with COVID-19. No potential participants were excluded.InterventionParticipants volunteered a nasopharyngeal swab and a venous blood sample that were tested for SARS-CoV-2 RNA and anti-SARS-CoV-2 spike glycoprotein antibodies, respectively. Results were interpreted in the context of prior illnesses and the hospital departments in which participants worked.Main outcome measureProportion of participants demonstrating infection and positive SARS-CoV-2 serology.ResultsThe point prevalence of SARS-CoV-2 viral carriage was 2.4% (n=13/545). The overall seroprevalence of SARS-CoV-2 antibodies was 24.4% (n=126/516). Participants who reported prior symptomatic illness had higher seroprevalence (37.5% vs 17.1%, χ2=21.1034, p<0.0001) and quantitatively greater antibody responses than those who had remained asymptomatic. Seroprevalence was greatest among those working in housekeeping (34.5%), acute medicine (33.3%) and general internal medicine (30.3%), with lower rates observed in participants working in intensive care (14.8%). BAME (Black, Asian and minority ethnic) ethnicity was associated with a significantly increased risk of seropositivity (OR: 1.92, 95% CI 1.14 to 3.23, p=0.01). Working on the intensive care unit was associated with a significantly lower risk of seropositivity compared with working in other areas of the hospital (OR: 0.28, 95% CI 0.09 to 0.78, p=0.02).Conclusions and relevanceWe identify differences in the occupational risk of exposure to SARS-CoV-2 between hospital departments and confirm asymptomatic seroconversion occurs in healthcare workers. Further investigation of these observations is required to inform future infection control and occupational health practices.

Sign in / Sign up

Export Citation Format

Share Document