scholarly journals Gut Mycobiota Dysbiosis in Pulmonary Tuberculosis Patients Undergoing Anti-Tuberculosis Treatment

2021 ◽  
Author(s):  
Demin Cao ◽  
Weihua Liu ◽  
Na Lyu ◽  
Boxing Li ◽  
Weibo Song ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tuberculosis Treatment ◽  
Tuberculosis Patients ◽  
Bacterial Microbiota

Numerous studies have shown that the gut bacterial microbiota is altered in active TB patients and that anti-TB drugs have profound and long-term impacts. However, as an integral part of the microbiota, fungi have rarely been studied.

scholarly journals EXTRAPLEURAL PNEUMOLYSIS FOR CAVITARY PULMONARY TUBERCULOSIS TREATMENT

2020 ◽  
pp. 15-20
Author(s):  
P. G. Gadzhieva ◽  
D. B. Giller ◽  
A. A. Glotov ◽  
O. Sh. Kesaev ◽  
V. V. Koroev ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Pathological Process ◽  
Tuberculosis Treatment ◽  
Long Term Results ◽  
Filling Material ◽  
Different Types ◽  
Positive Effect ◽  
Observation Period

Objective. To increase efficiency of cavitary pulmonary tuberculosis treatment by developing modern indications and technology of extrapleural pneumolysis with filling material.Material and methods. We reviewed 25 patients with cavitary pulmonary tuberculosis and bacterial excretion who had undergone extrapleural pneumolysis with different types of filling material in 2004–2015. In 16 cases, we performed surgery in patients with one lung.Results. 56% of operated patients demonstrated extensively drug-resistant TB, 40% had multidrug-resistant TB. Cavities were closed and bacterial excretion ceased in 92% of patients at discharge. Long-term results with observation period from 1 to 12 years were analyzed in 24 patients, 17 (71%) of them had complete clinical efficacy.Conclusion. Extrapleural pneumolysis is a mini-invasive surgical treatment that can prove positive effect in patients with non-fibrotic changes in a cavity wall and pathological process in upper parts of the lungs. 

scholarly journals The Effect of Side Effects Tuberculosis Treatment in the Early Stage Towards Compliance with Tuberculosis Patients

2021 ◽  
Vol 5 (01) ◽  
pp. 29-32
Author(s):  
Joko Sapto Pramono ◽  
Nilam Noorma ◽  
Andi Lis Arming Gandini ◽  
Sopia Fitriani
Keyword(s):  
Side Effects ◽  
Pulmonary Tuberculosis ◽  
Health Workers ◽  
Early Stage ◽  
Treatment Compliance ◽  
Tuberculosis Treatment ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Early Stages ◽  
Significant Difference

Pulmonary tuberculosis treatment causes various side effects including nausea and vomiting, itching, vision problems, and anemia. Drug side effects in the early stages are one of the causes of non-adherence to complete treatment. The purpose of this study was to analyze the effect of the side effects Tuberculosis treatment in the early stages on treatment compliance for tuberculosis patients. This study used a cross sectional design. Samples were taken as many as 71 respondents, the instruments used were side effects of early-stage tuberculosis treatment and compliance with tuberculosis treatment in tuberculosis patients from the Morisky Medication Adherence Scale (MMAS). The results of the study found 97.7% adherent and 2.3% non-adherent, 39.5% mild side effects and 60.5% severe side effects. Chi-square test showed that no significant difference between the side effects of TB treatment in the early stages of tuberculosis treatment compliance in patients p = 0.669 at significant level of 95% (α = 0.05). There was no effect between the side effects of Tuberculosis treatment in the early stages of treatment compliance for Tuberculosis patients. It was recommended that health workers continue to monitor the side effects of tuberculosis treatment and provide motivation to carry out treatment completely. Keywords: side effects; early stage; treatment; pulmonary tuberculosis; compliance

Literature Review : Evaluasi Peer Group Support dan Family Support Terhadap Kepatuhan Pengobatan Pada Pasien Tuberkulosis Paru

2021 ◽  
Vol 11 (1) ◽  
pp. 51
Author(s):  
Suarnianti Suarnianti ◽  
Chairul Hasan Selan ◽  
Susi Sastika Sumi
Keyword(s):  
Literature Review ◽  
Pulmonary Tuberculosis ◽  
Family Support ◽  
Systematic Literature Review ◽  
Peer Group ◽  
Tuberculosis Treatment ◽  
Google Scholar ◽  
Group Support ◽  
Tuberculosis Patients ◽  
Support Family

Tuberculosis (TB) is an infectious disease which is the leading cause of ill health, one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent (ranking above HIV / AIDS). WHO estimates that there are 23,000 cases of MDR / RR in Indonesia. In 2017 there were 442,000 TB cases recorded in the program, of which an estimated 8,600-15,000 MDR / RR TB, (estimated 2.4% of new cases and 13% of previously treated TB patients), but only 27.36% treated. The aim of this literature is to evaluate peer group support and family support on treatment adherence to pulmonary tuberculosis patients. This study used a systematic literature review design. Articles were collected through the PubMed and Google Scholar databases published from 2016-2020 using the keywords peer group support, family support, medication adherence, pulmonary tuberculosis. The results of the literature review showed that providing peer group support or family support can have an impact positive for pulmonary tuberculosis patients. The conclusion in this study is that patients who get support from either peer group support or family support can significantly improve compliance with pulmonary tuberculosis treatment so that it can increase the success rate of pulmonary tuberculosis treatment. Keywords: peer group support; family support; treatment compliance; pulmonary tuberculosis ABSTRAK Tuberkulosis (TB) adalah penyakit menular yang merupakan penyebab utama masalah kesehatan yang buruk, salah satu dari 10 penyebab utama kematian di seluruh dunia dan penyebab utama kematian dari satu agen infeksi tunggal (peringkat di atas HIV / AIDS). WHO memperkirakan ada 23.000 kasus MDR/RR di Indonesia. Pada tahun 2017 kasus TB yang tercatat di program ada sejumlah 442.000 kasus yang mana dari kasus tersebut diperkirakan ada 8.600-15.000 MDR/RR TB, (perkiraan 2,4% dari kasus baru dan 13% dari pasien TB yang diobati sebelumnya), tetapi cakupan yang diobati baru sekitar 27,36%. Tujuan Literatur ini untuk mengevaluasi peer group support dan family support terhadap kepatuhan pengobatan pasien tuberkulosis paru. Penelitian ini menggunakan desain systematic literature review. Artikel dikumpulkan melalui database PubMed dan Google Scholar yang dipublikasikan dari tahun 2016-2020 dengan menggunakan kata kunci peer group support, family support, kepatuhan pengobatan, tuberkulosis paru. Hasil literature review menunjukkan bahwa pemberian peer group support atau family support dapat memberikan dampak yang positif kepada pasien tuberkulosis paru. Kesimpulan dalam penelitian ini bahwa pasien yang mendapatkan dukungan baik peer group support atau family support secara signifikan dapat meningkatkan kepatuhan pengobatan tuberkulosis paru sehingga dapat meningkatkan tingkat keberhasilan pengobatan tuberkulosis paru Kata kunci: peer group support; family support; kepatuhan pengobatan; tuberkulosis paru

scholarly journals Adherence to Tuberculosis Treatment among Migrant Pulmonary Tuberculosis Patients in Shandong, China: A Quantitative Survey Study

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e52334 ◽  
Author(s):  
Chengchao Zhou ◽  
Jie Chu ◽  
Jinan Liu ◽  
Ruoyan Gai Tobe ◽  
Hong Gen ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tuberculosis Treatment ◽  
Survey Study ◽  
Tuberculosis Patients ◽  
Quantitative Survey

scholarly journals Analysis of tuberculosis treatment outcomes among pulmonary tuberculosis patients in Bahawalpur, Pakistan

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Muhammad Atif ◽  
Zainab Anwar ◽  
Razia Kaneez Fatima ◽  
Iram Malik ◽  
Saima Asghar ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Treatment Outcomes ◽  
Tuberculosis Treatment ◽  
Tuberculosis Patients

scholarly journals Prevalence of Fluoroquinolone Resistance among Tuberculosis Patients in Shanghai, China

2009 ◽  
Vol 53 (7) ◽  
pp. 3170-3172 ◽  
Author(s):  
Peng Xu ◽  
Xia Li ◽  
Ming Zhao ◽  
Xiaohong Gui ◽  
Kathryn DeRiemer ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Molecular Marker ◽  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Tuberculosis Treatment ◽  
Fluoroquinolone Resistance ◽  
First Line ◽  
Tuberculosis Patients ◽  
Resistant Strains ◽  
Line Drug

ABSTRACT We determined the prevalence of fluoroquinolone resistance among the isolates of Mycobacterium tuberculosis from 605 pulmonary tuberculosis patients in Shanghai, China. Mutations in gyrA were found in 81.5% of phenotypically fluoroquinolone-resistant isolates and were used as a molecular marker of fluoroquinolone resistance. gyrA mutations were detected in 1.9% of strains pan-susceptible to first-line drugs and 25.1% of multidrug-resistant strains. Fluoroquinolone resistance was independently associated with resistance to at least one first-line drug and prior tuberculosis treatment.

scholarly journals Diagnostic pathways and direct medical costs incurred by new adult pulmonary tuberculosis patients prior to anti-tuberculosis treatment – Tamil Nadu, India

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0191591 ◽  
Author(s):  
Karun Sandeep Veesa ◽  
Kamalabhai Russell John ◽  
Patrick K. Moonan ◽  
Saravanakumar Puthupalayam Kaliappan ◽  
Krishna Manjunath ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tamil Nadu ◽  
Medical Costs ◽  
Tuberculosis Treatment ◽  
Tuberculosis Patients ◽  
Direct Medical Costs ◽  
Diagnostic Pathways
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