scholarly journals The Effect of Side Effects Tuberculosis Treatment in the Early Stage Towards Compliance with Tuberculosis Patients

2021 ◽  
Vol 5 (01) ◽  
pp. 29-32
Author(s):  
Joko Sapto Pramono ◽  
Nilam Noorma ◽  
Andi Lis Arming Gandini ◽  
Sopia Fitriani
Keyword(s):  
Side Effects ◽  
Pulmonary Tuberculosis ◽  
Health Workers ◽  
Early Stage ◽  
Treatment Compliance ◽  
Tuberculosis Treatment ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Early Stages ◽  
Significant Difference

Pulmonary tuberculosis treatment causes various side effects including nausea and vomiting, itching, vision problems, and anemia. Drug side effects in the early stages are one of the causes of non-adherence to complete treatment. The purpose of this study was to analyze the effect of the side effects Tuberculosis treatment in the early stages on treatment compliance for tuberculosis patients. This study used a cross sectional design. Samples were taken as many as 71 respondents, the instruments used were side effects of early-stage tuberculosis treatment and compliance with tuberculosis treatment in tuberculosis patients from the Morisky Medication Adherence Scale (MMAS). The results of the study found 97.7% adherent and 2.3% non-adherent, 39.5% mild side effects and 60.5% severe side effects. Chi-square test showed that no significant difference between the side effects of TB treatment in the early stages of tuberculosis treatment compliance in patients p = 0.669 at significant level of 95% (α = 0.05). There was no effect between the side effects of Tuberculosis treatment in the early stages of treatment compliance for Tuberculosis patients. It was recommended that health workers continue to monitor the side effects of tuberculosis treatment and provide motivation to carry out treatment completely. Keywords: side effects; early stage; treatment; pulmonary tuberculosis; compliance

scholarly journals Determinan Kepatuhan Minum Obat Pasien Tuberkulosis Paru

2019 ◽  
Vol 1 (2) ◽  
pp. 176-185
Author(s):  
Christine Vita Gloria ◽  
Zulmeliza Rasyid ◽  
Sherly Vermita W ◽  
Elmia Kursani ◽  
Bizanti Umayyah
Keyword(s):  
Pulmonary Tuberculosis ◽  
Health Center ◽  
Family Support ◽  
Health Workers ◽  
Treatment Compliance ◽  
P Value ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Lung Tuberculosis

This study aims to see whether the determinants are related to treatment compliance for pulmonary tuberculosis patients at the 2019 health center. This type of research is a quantitative observational cross-sectional design. The results showed that with a P value of 0.05, there was a significant relationship between knowledge (P value = 0.005 and POR = 14.276), attitudes (P value = 0.506 and POR = 1.615), family support (P value = 0.038 and POR = 1,961), the role of health workers (P values = 0.026 and POR = 4.440), with medication adherence for pulmonary tuberculosis patients. Conclusions, of the 4 variables there are 3 variables related to adherence to taking pulmonary TB drugs in the Work Area of the Siak Hulu II Health Center, namely knowledge, family support, and the role of health workers and 1 unrelated variable, attitude.   Keywords: Obedience, Medicine, Lung Tuberculosis

scholarly journals Medical Compliance Determinants for Tuberculosis Patients in Palembang

2020 ◽  
Vol 11 (3) ◽  
pp. 272-284
Author(s):  
Uca Ayu Frama Diesty ◽  
RM. Suryadi Tjekyan ◽  
M.Zulkarnain Zulkarnain
Keyword(s):  
Health Workers ◽  
Treatment Compliance ◽  
Adherence To Treatment ◽  
Chi Square ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Resistant Tuberculosis ◽  
The World ◽  
Chi Square Test ◽  
Cross Sectional Design

The majority of countries in the world have tuberculosis, including Indonesia, which has the third rank in the world. This is due to a large number of sufferers who were not successfully cured. One of the factors that influence the recovery of tuberculosis patients is adherence to taking anti-tuberculosis drugs for a certain period of time. Non-adherence to treatment can exacerbate the risk of disease because it can lead to MDR (Multi Drugs Resistant) tuberculosis. This study aims to analyze the determinants of tuberculosis treatment compliance in the city of Palembang. This study used an analytical study with a semi-quantitative approach, with a cross-sectional design. Sampling was carried out by proportional random sampling at 39 Puskesmas Kota Palembang, a total of 243 samples that met the inclusion and exclusion criteria. Data collection was carried out by means of interviews using a questionnaire. Data were analyzed using the chi-square test and multiple logistic regression. Obtained adherence to treatment of tuberculosis patients by 42.8%. There was a significant relationship between perceived benefits (p = 0.000; OR = 3.556), family support (p = 0.000; OR = 3.512), support from health workers (p = 0.001; OR = 2.712), knowledge (p = 0.018; OR = 2,027) with adherence to treatment of tuberculosis patients. The level of compliance with tuberculosis patients in Palembang City is still low, namely 42.8%. The most important determinant of adherence is perceived benefit with a 3.556 times greater opportunity after controlling for other variables.

scholarly journals An audit of diagnosis and treatment of tuberculosis in Ethiopia

2014 ◽  
Vol 6 (1) ◽  
Author(s):  
Valerie J. Ehlers ◽  
Getahun S. Aragaw
Keyword(s):  
Pulmonary Tuberculosis ◽  
Healthcare Providers ◽  
Cross Sectional Study ◽  
Tuberculosis Treatment ◽  
Diagnosis And Treatment ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Resistant Tuberculosis ◽  
National Tuberculosis ◽  
Smear Negative

Background: Despite the existence of national tuberculosis guidelines (NTG) in Ethiopia, the incidence and prevalence of tuberculosis did not decline markedly. Audits could attempt to determine whether or not healthcare professionals actually implemented these guidelines, as non-implementation could contribute to suboptimal tuberculosis treatment outcomes.Aim: To evaluate healthcare providers’ implementation of Ethiopia’s NTG during the diagnosis and treatment of tuberculosis in order to enhance tuberculosis treatment outcomes.Methods: A descriptive, cross-sectional study design was used.Results: Healthcare providers implemented the NTG during tuberculosis diagnosis for female (60.9%; n = 67) and male (56.1%; n = 69) patients. The correct numbers of anti-tuberculosis pills, complying with the NTG recommendations, were prescribed for 91.8% (n = 101) of the women and for 90.2% (n = 111) of the men. However, both over- and under-prescriptions of anti-tuberculosis drugs occurred. There was an over-diagnosis of smear-negative pulmonary tuberculosis. Only 2.6% (n = 2) of the 76 smear-negative pulmonary tuberculosis patients had been diagnosed correctly.Conclusion: Implementation of the NTG should be enhanced, especially with regard to the diagnosis of smear-negative pulmonary tuberculosis patients and the correct prescription of anti-tuberculosis drugs. This would help to increase the number of correctly-diagnosed and -treated tuberculosis patients, improve tuberculosis treatment outcomes, decrease the spread of tuberculosis and prevent the development of multi-drug-resistant tuberculosis strains.

scholarly journals Assessment of Depression among Pulmonary Tuberculosis Patients: A Cross-Sectional Study from Pakistan.

2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Madeeha Malik ◽  
Rida Nasir ◽  
Azhar Hussain
Keyword(s):  
Pulmonary Tuberculosis ◽  
Financial Burden ◽  
Cross Sectional Study ◽  
Study Patient ◽  
Sectional Study ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Baseline Phase ◽  
Tuberculosis Patients ◽  
Significant Difference

<strong>Background:</strong> Depression is a condition that is often co-morbid to tuberculosis and can lead to increased morbidity and mortality associated with tuberculosis. The current prevalence of depression worldwide among individuals receiving treatment for TB ranged from 11.3% to 80.2%, with a mean weighted prevalence of 48.9%. The aim of the current study was to assess depression among tuberculosis patients in Pakistan. <strong>Methods </strong>A descriptive cross-sectional study design was used to evaluate depression among pulmonary tuberculosis patients in Pakistan. All the public and private tertiary healthcare facilities treating TB located in Rawalpindi and Islamabad were included in the study. Patient health questionnaire-9 (PHQ-9) was used to collect data from 382 patients of pulmonary tuberculosis. Non-parametric tests, Mann-Whitney and Kruskal-Wallis, were performed to find out the difference among different variables. <strong>Results &amp; Conclusion: </strong>Kruskal-Wallis and Mann-Whitney (p ≥ 0.05) were performed to find out the differences among different variables. Significant difference between different income levels (p=0.002), duration of treatment (p=0.01), phase of treatment (p=0.03) and type of treatment (p=0.001) were observed. Moderate depression was observed among patients at baseline and had duration of treatment less than a month. The present study concluded that majority of patients suffering from tuberculosis suffered from some sort of depression. This depression was more evident at baseline phase of therapy. Patients undergoing directly observed therapy appeared to be more depressed due to increased stigma along with increase in financial burden. Counseling and psychotherapy can play a massive role in combating depression and improving medication adherence in TB patients.

Factors Associated with Treatment Outcomes in Patients with Pulmonary Tuberclosis

2021 ◽  
Vol 15 (9) ◽  
pp. 3091-3095
Author(s):  
Akram Afzal ◽  
Murad Ahmad ◽  
Haseeb Ghaffar
Keyword(s):  
Pulmonary Tuberculosis ◽  
Treatment Outcomes ◽  
Successful Treatment ◽  
Tuberculosis Treatment ◽  
P Value ◽  
Treatment Rate ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Factors Associated ◽  
Treatment Category

Background and Aim: Tuberculosis (TB) is one of the major sources of health problems in developing countries. An effective strategy for tuberculosis treatment can be evaluated with key indicators known as TB control program with their treatment outcomes. Hence, the purpose of this study was to evaluate the factors associated with the treatment outcome of pulmonary tuberculosis in patients. Methods: This cross-sectional study was carried out on 129 Tuberculosis patients in the department of Pulmonology, Gulab Devi Hospital Lahore from November 2020 to April 2021. Demographic details, clinical examination, and treatment outcomes were evaluated. All the data were extracted from the hospital medical records. Successful treatment outcomes predictors were assessed using bivariate and multivariate regression. SPSS version 20 was used for data analysis. Results: Of the total 129 tuberculosis patients, 59 (46%) were male and 70 (54%) were females. The overall mean age was 26.54±5.62 years. The overall prevalence of successful treatment rate was 113 (87.6%). Out of 113, the prevalence of cured and complete treatment patients was 57 (50.4%) and 56 (49.6%) respectively. Based on logistic regression models, various parameters with their respective adjustment odds ratio (AOR) were as follows; age 21-40 years (AOR= 2.67, 95% CI=1.32-6.12, p-value=0.003), treatment category (AOR=4.62, 95% CI=1.12-16.74, p-value=0.027), and smear-positive pulmonary tuberculosis (AOR=3.47; 95% CI=1.76-6.69, p-value<0.001) were significantly related with treatment outcomes. Conclusion: Our study reported that the overall prevalence of successful treatment was 87.6%. Though, the rate of overall successful treatment was found satisfactory, but, to meet international standard strategy for tuberculosis, still, improvement needs to be achieved. Age, treatment category, and tuberculosis types were significantly correlated with treatment outcomes. Keywords: Pulmonary Tuberculosis; Treatment Outcomes; TB Smears

Determination some Immunological Aspects in Pulmonary Tuberculosis Patients in Qadisiyah Province

2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Syoof Khowman Alramahy ◽  
Akram Hadi Hamza
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Statistical Difference ◽  
Positive Culture ◽  
Control Group ◽  
Tuberculosis Patients ◽  
Significant Difference ◽  
Lowenstein Jensen ◽  
The Mean ◽  
Igg Level

This study was carried out to study of some immunological aspects among the pulmonary Tuberculosis patients infected with causative agent, Mycobacterium tuberculosis. A Total of 200 sputum samples were collected from patients attending the consultant Clinic for Chest and Respiratory disease center, Diwaniya. Control group (No=15) also included. According to acid fast stain of sputum, the patients were classified as positive (No=91,45.5%) and negative (No=109,54.5, Lowenstein Jensen medium used for the cultivation of samples, on which 70% of sputum samples where positive culture for this microorganism. The grown microorganism were identified as M. tuberculosis, based on positive A.F.B, Niacin producers ,negative for catlase at 68c. The mean IgG level was l184.053±76.684 mg/100 ml in tuberculosis group compared with 1016.533 ± 44.882 mg/100ml in control group, rendering the statistical difference significant. For IgA and IgM levels, they were at mean of 315.880±38.552 mg/100 ml and 119.527±8.464 mg/100 ml in control group compared with 396.358±38.776 mg/100 ml and 134.207±11.696 mg/100 ml in patients group respectively with significant difference

EVALUASI EFEKTIFITAS PENGGUNAAN MEDIA DALAM MENURUNKAN PREVALENSI TUBERKULOSIS DI BALAI PEMBERANTASAN DAN PENCEGAHAN PENYAKIT PARU PAMEKASAN

2018 ◽  
Vol 1 (2) ◽  
pp. 64-75
Author(s):  
Qurrotu Aini
Keyword(s):  
Pulmonary Tuberculosis ◽  
Health Workers ◽  
Visual Media ◽  
Communication Education ◽  
Tuberculosis Patients ◽  
Inhibiting Factors ◽  
Study Evaluation ◽  
Intensive Use ◽  
Internal Networks ◽  
Lack Of Commitment

Pulmonary tuberculosis is still a serious health problem that needs to be equipped with appropriate countermeasures and accurate. The increase in cases and deaths caused by pulmonary tuberculosis, among others, because it is not threated any of them do not understand have been infected with the TB bacillus so that the prevalence of tuberculosis is still quite high. Therefore, the necessary handling seriously through health education role that communication education with intensive use of media that will reduce the prevalence or at least remain. In general. The purpose of the study to evaluate the effectivesness oh the use of media in reducing the prevalence of tuberculosis. The study “evaluation of Effectiveness of Media in Reducing Prevalence Of Tuberculosis in The Central Eradication and Prevention of Lung Disease Pamekasan “ use purposive sampling with the snowball method. Sample research is pulmonary tuberculosis  patients treated in BP4 much as 3 respondents. The results showed three informants as respondents are all in the first 2 months visiting tuberculosis drug taking as much as 8 times visit support the availability of infrastructure, knowledge of personel. Strategy, advocacy, resoueces and funding are two inhibiting factors lack of education and knowledge of the patients, the lack of commitment oh health workers all of the prevalence of tuberculosis as well as visual media is the most effective in reducing the prevalence of tuberculosis. Sugestions for researchers to address the increasing prevalence of lung integration across every sector and cross-sectoral programs to develop internal networks and external networks.

scholarly journals POS0140 URATE-LOWERING THERAPY REDUCES NON-EPISODIC FOOT PAIN IN PATIENTS WHO FAIL TO MEET ACR/EULAR 2015 GOUT CLASSIFICATION CRITERIA: AN EFFECT PREDICTED BY ULTRASOUND

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 282.1-282
Author(s):  
R. Flood ◽  
C. Kirby ◽  
Y. Alammari ◽  
D. Kane ◽  
R. Mullan
Keyword(s):  
Early Stage ◽  
Serum Urate ◽  
Classification Criteria ◽  
Disease Classification ◽  
Foot Pain ◽  
Cross Sectional ◽  
Baseline Serum ◽  
First Metatarsophalangeal Joint ◽  
Lowering Therapy ◽  
Significant Difference

Background:Emerging evidence that the joints of asymptomatic hyperuricaemic individuals contain monosodium urate (MSU) deposits and that alternative presentations of foot pain occur in hyperuricaemia suggests that preclinical phases may occur prior to a first episodic gout attack. (1) This case–control study evaluates urate deposition in hyperuricaemic individuals not fulfilling the current gout classification criteria, as well as a potential therapeutic role for urate lowering therapy (ULT).Objectives:To investigate whether ULT reduces non-episodic foot pain in patients who fail to meet ACR/EULAR 2015 gout classification criteria.Methods:Following informed consent, hyperuricaemic individuals with persistent, non-episodic foot pain (n=53) not fulfilling ACR/EULAR 2015 gout classification criteria, were compared with asymptomatic hyperuricaemic controls (n=18). Ultrasound (US) of bilateral first metatarsophalangeal (MTP) joints and features of MSU deposition including double contour (DC) sign, tophus and juxta-articular erosion were recorded. Cases only were treated with febuxostat or allopurinol daily for 6 months. Serum urate, 24-hour and 7-day visual analogue score (VAS) 0–100 mm pain scales and the Manchester Foot Pain and Disability Index (MFPDI) were recorded before treatment and after 3 and 6 months. MTP Ultrasound was repeated after a minimum of 6 months on treatment.Results:53 hyperuricaemic individuals with persistent, non-episodic foot pain not meeting the ACR/EULAR 2015 gout classification criteria were recruited. At baseline MTP US DC sign, erosion and tophus occurred in 62.5%, 20.8% and 49% of cases, respectively. No US features of gout occurred in controls. No significant difference was seen in baseline serum urate between cases (481±14 mg/dL) versus controls (437±14; p=NS). Serum urate in cases fell at 3 months (325±25; p<0.01) and 6 months (248±19; p<0.01). For cases, baseline 24-hour pain VAS (46±3.9) reduced at 3 months (32±4.1; p<0.05) and 6 months (21±5.2; p<0.05) of ULT. The 7-day pain VAS (59±3.9) decreased at 3 months (35±4.5; p<0.05) and 6 months (30±5.3; P<0.05). MFPDI (17±1.4) decreased at 3 month (13±1.8; p=<0.05) and 6 months (11±2.2; p=<0.05). When cases were grouped according to the presence (N=33) or absence (N=18) of DC sign on baseline US, no differences were observed for baseline pain scores. Following ULT however, 24-hour pain VAS were significantly lower in DC positive patients at 3 months (22±4.48 DC positive vs 42±6.14 DC negative; p<0.05) and 6 months (12.±5.4 vs 33±8.4; p<0.05). The 7-day pain VAS were significantly lower in DC positive patients at 3 months (23±4.6 vs 47±6.6; p<0.05) and MFDPI were significantly lower in DC positive patients at 3 months (10±1.9 DC positive vs 19±2.9 DC negative; p<0.05).Conclusion:These findings indicate that persistent, non-episodic foot pain in hyperuricaemia is both associated with US features of MSU deposition and is responsive to ULT. Symptomatic hyperuricaemia occurring prior to episodic gout therefore represents an earlier or alternative disease presentation. Changes to the ACR/ EULAR classification criteria to include non-episodic foot pain in the presence of US features of gout may increase the sensitivity of disease classification at an early stage, leading to improved future treatment strategies and long-term outcomes.References:[1]Stewart S, Dalbeth N, Vandal AC, Rome K. Characteristics of the first metatarsophalangeal joint in gout and asymptomatic hyperuricaemia: A cross-sectional observational study. J Foot Ankle Res. 2015;8(1):1–8.Disclosure of Interests:None declared

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