scholarly journals AB0717 PREVALENCE OF MIGRAINE AND NEUROPATHIC PAIN AMONG PATIENTS WITH RHEUMATIC DISEASES

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1390.1-1390
Author(s):  
S. Miladi ◽  
M. Yasmine ◽  
A. Fazaa ◽  
S. Mariem ◽  
K. Ouenniche ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Rheumatic Diseases ◽  
Disease Duration ◽  
Self Assessment ◽  
Factors Associated ◽  
Sociodemographic Data ◽  
Inflammatory Mechanism ◽  
High Prevalence ◽  
The Mean ◽  
Interview Questionnaire

Background:Pain in rheumatic diseases (RD) is primarily due to mechanical or inflammatory mechanism, but neuropathic pain (NP) component is yet to be fully evaluated and described, with a particular attention to the distinction with nociceptive pain [1].Objectives:The aim of our study was to assess the prevalence of migraine and neuropathic pain in patients with RD and to explore factors associated with NP.Methods:Prospective study including patients with rheumatoid arthritis (RA) and spondylarthritis (SpA) were invited to complete a validated self-assessment questionnaires. Sociodemographic data as well as disease related characteristics were recorded. Migraine was diagnosed according to the IHS migraine diagnostic criteria. NP was evaluated using DN4 (Douleur Neuropathique 4 Questions) and Pain DETECT questionnaire (PDQ). Neuropathic pain was retained in case of a total score of 4 or more at DN4-interview questionnaire or a score ≥19 with the PDQ.Results:A total of 60 patients with RD were included (42 RA/18 SpA). Females outnumbered males (sex-ratio=1.7). The mean age was 51.3 ± 13.1 years [18-75] and the mean disease duration was 11.9 ±5.6 [1-23] years. The prevalence of migraine was 15%. This latter was higher among women than men and among RA patients than SpA (18% vs 9%, 16.6% vs 11.2%) with no statistically significant correlation (p=0,329, 0,581 respectively). Parameters associated with a higher prevalence of migraine were an older age (p=0,042). However, there was no correlation between the presence of migraine and the type of the RD, disease duration or the level of anxiety (p=0,059, p=0,459 respectively). Chronic pain with neuropathic characteristics was found in 21.7% with the DECT score and 16.7% with DN4 questionnaire. NP was most prevalent among patients with comorbidities (28.5% vs 6%, p=0.021) and with higher body mass index (p=0.01). Prevalence was significantly higher in the RA group (19%) than in the SpA group (11%) without a statistically significant correlation (p=0.45). Similarly, NP was not associated with Salazopyrine intake (p=0.9).Conclusion:We found a high prevalence of migraine and NP in our sample of patients with RD. It seems therefore important to check the presence of migraine or NP especially in patients with comorbidities and older ones.References:[1]Bailly F, Cantagrel A, Bertin P, et al. Part of pain labelled neuropathic in rheumatic disease might be rather nociplastic. RMD Open. 2020;6:e001326.Disclosure of Interests:None declared

scholarly journals Treatment of notalgia paresthetica with low dose pregabalin: Retrospective evaluation of 13 patients

2021 ◽  
Vol 12 (4) ◽  
pp. 395-397
Author(s):  
Sertaç Şener ◽  
Fadime Kilinç ◽  
Ayşe Akbaş
Keyword(s):  
Neuropathic Pain ◽  
Retrospective Study ◽  
Low Dose ◽  
Disease Duration ◽  
Symptomatic Treatment ◽  
Good Option ◽  
Pain Medicine ◽  
Retrospective Evaluation ◽  
The Mean ◽  
Notalgia Paresthetica

Background: Notalgia paresthetica (NP) is a sensory neuropathic syndrome characterized by chronic itching of the unilateral mid-back. Topical and systemic symptomatic treatments have been used to date. In recent years, neuropathic pain medicine has been used to relieve the symptoms of the disease. The aim of this study was to determine the effectiveness of pregabalin in notalgia paresthetica. Materials and Methods: In this study, the files of the patients with a diagnosis of NP and treated with pregabalin for at least one month in the period between 2016 and 2018 were evaluated retrospectively. Results: Thirteen cases of NP treated with low-dose (up to 150 mg/day) pregabalin were evaluated, and 9 (70%) patients exhibited a good response in this retrospective study. All patients were female and the mean age was 53.5 (31–71) ± 10.3 years. The mean disease duration was 6.1 (1–10) ± 4.1 years. Conclusion: Treatment with low-dose pregabalin may be a good option for the symptomatic treatment of NP.

scholarly journals Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases

2020 ◽  
Vol 9 (6) ◽  
pp. 1890 ◽  
Author(s):  
Sylvain Mathieu ◽  
Marion Couderc ◽  
Bruno Pereira ◽  
Jean-Jacques Dubost ◽  
Sandrine Malochet-Guinamand ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Rheumatic Diseases ◽  
Tnf Alpha ◽  
Inflammatory Rheumatic Diseases ◽  
Self Assessment ◽  
Clinical Control ◽  
Chronic Inflammatory Rheumatic Diseases ◽  
High Level ◽  
Assessment Questionnaire ◽  
Inhibitor Treatment

To investigate the physiopathology of pain in chronic inflammatory rheumatic diseases (CIRDs), we assessed the prevalence of migraine and neuropathic pain in 499 patients with CIRDs. We studied 238 patients with rheumatoid arthritis, 188 with spondyloarthritis (SpA), 72 with psoriatic arthritis (PsA), and 1 unclassified. Migraine was diagnosed according to IHS migraine diagnostic criteria. Neuropathic pain was diagnosed when patients scored at least 3 on the DN4 questionnaire. Participants completed a validated self-assessment questionnaire. Migraine prevalence was 34% (165/484), and it was highest in PsA. Risk factors for migraine were a high level of anxiety, female sex, young age, and TNF-alpha inhibitor treatment (OR = 1.90 (1.13–3.25)). Besides, high disease activity was a risk factor in SpA. Blood CRP level was not significantly associated with migraine. Of 493 patients with CIRDs, 21.5% had chronic pain with neuropathic characteristics. Compared to the French general population, these patients had significantly higher prevalences of migraine (two-fold) and neuropathic pain (three-fold). This study showed that migraine and neuropathic pain frequently occurred in patients with rheumatic diseases. Therefore, upon reporting residual pain, these patients should be checked for the presence of migraine or neuropathic pain, despite adequate clinical control of rheumatic disease.

scholarly journals High prevalence of fatigue in contemporary patients with multiple sclerosis

2021 ◽  
Vol 7 (1) ◽  
pp. 205521732199982
Author(s):  
Line Broch ◽  
Cecilia Smith Simonsen ◽  
Heidi Øyen Flemmen ◽  
Pål Berg-Hansen ◽  
Åshild Skardhamar ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Disease Severity ◽  
Daytime Sleepiness ◽  
Disease Duration ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Disease Modifying Drugs ◽  
High Prevalence ◽  
The Mean ◽  
Anxiety Depression

Objective The prevalence of multiple sclerosis (MS)-related fatigue may have changed due to new diagnostic criteria and new disease modifying drugs. We aimed to assess the prevalence of fatigue in a contemporary MS cohort, and to explore associations between fatigue and clinical and demographic factors. Methods This is a cross-sectional study of the MS population in three Norwegian counties. Fatigue was assessed with the Fatigue Scale for Motor and Cognitive Functions (FSMC). We also assessed self-reported anxiety, depression and daytime sleepiness. Results The response rate was 64% (1599/2512). The mean age of the participants was 52 ± 13 years, median EDSS was 2.5 (IQR 1.5-3.0) and median disease duration from onset was 16 years (IQR 8-25). We found a prevalence of fatigue of 81%. Women had a higher prevalence of fatigue than men (83% vs 78%, p = 0.02). The prevalence increased with age (p < 0.001) and with increasing disease severity (p < 0.001), but in multivariate analyses, only sex and disease severity remained independent determinants of fatigue. Anxiety, depression, and daytime sleepiness were more prevalent in patients with fatigue than in those without fatigue (all p-values < 0.001). Conclusion The prevalence of fatigue is high in contemporary patients with MS. Fatigue is associated with female sex and level of disability, as well as with anxiety, depression and excessive daytime sleepiness.

scholarly journals AB0173 FACTORS ASSOCIATED WITH FATIGUE AND PERSISTENT FATIGUE IN RHEUMATOID ARTHRITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1113.1-1113
Author(s):  
A. Fazaa ◽  
H. Boussaa ◽  
K. Ouenniche ◽  
S. Miladi ◽  
M. Sellami ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Physical Activity ◽  
Negative Correlation ◽  
Disease Duration ◽  
Significant Negative Correlation ◽  
Professional Status ◽  
Factors Associated ◽  
Severe Fatigue ◽  
Persistent Fatigue ◽  
The Mean

Background:Fatigue is a common and debilitating symptom in patients with rheumatoid arthritis (RA). Fatigue in RA is poorly understood and appears to be multifactorial. Interactions between three factors were suggested: ‘personal’, ‘disease processes’, and ‘cognitive, behavioural’.Objectives:The aim of this study was to determine factors associated with fatigue and persistent fatigue in RA.Methods:We conducted a longitudinal study including patients with RA (ACR/EULAR 2010). Patients with other acute or chronic diseases that may induce fatigue (such as cancer, infection or depression) were excluded. Patients were evaluated at inclusion (T0) and 12 months later (T12). Demographic and disease-related data were collected: age, gender, professional status, physical activity, disease duration, Rheumatoid Factor (RF), Anti-citrullinated peptides antibodies (ACPA), pain Visual Analog Scale (VAS), Erythrocyte Sedimentation Rate (ESR), C Protein Reactive (CRP), Disease Activity Score 28 (DAS28), and Health Assessment Questionnaire (HAQ). Fatigue was assessed using the Functional Assessment of Chronic Illness Therapy – Fatigue (FACIT-F) which is a short 13-item questionnaire validated in RA. The score FACIT-F ranges between 0 and 52. Fatigue was considered mild if the FACIT-F score was ≥40, moderate if 20≤FACIT-F<40 and severe if 0≤FACIT-F<20. We defined ‘persistent fatigue’ as reported fatigue at T0 and T12. A p value inferior to 0.05 was considered significant.Results:We included 100 patients (84 women and 16 men) with a mean age of 49.5±10 years old [18-65]. Among them, 25% were professionally active and 15% had a regular physical activity. At inclusion, the mean disease duration was 87.3 months [1-360]. RF and ACPA were positive in 75% and 72.6% of cases respectively. The mean pain VAS was 49 cm [0-100]. The mean levels of ESR and CRP were 38.1 mm [10-120] and 10.8 mg/l [2-61] respectively. The mean DAS28 ESR was 3.68 [1.90-8.33] and the mean HAQ score was 0.90 [0-2.75].The mean FACIT-F score was 27.1 [0-51] at T0. Fifty-seven percent of patients had moderate fatigue and 26% had severe fatigue. At T12, the mean FACIT-F score was 33.4 [5-50]. Persistent severe fatigue was noted in 17% of patients.A significant negative correlation was noted between FACIT-F score at T0 and the following variables: age (r=-0,258, p=0.01), pain VAS (r=-0,605, p<0.001), ESR (r=-0,621, p<0.001), DAS28 ESR (r=-0.744, p<0.001), and HAQ (r=-0.634, p<0.001).A significant negative correlation was noted between FACIT-F score at T12 and the following variables: age (r=-0,229, p=0.022), disease duration (r=-0,296, p=0.003), pain VAS (r=-0,754, p<0.001), ESR (r=-0,405, p<0.001), CRP (r=-0,468, p<0.001), DAS28 ESR (r=-0.744, p<0.001), and HAQ (r=-0.678, p<0.001).Fatigue and persistent fatigue were not associated with gender, professional status, physical activity, and immunological profile.Multivariable analysis showed that DAS28 ESR (OR=-0.157, 95% CI [-4.614;-0.153], p=0.036) and HAQ (OR=-0.563, 95% CI [-6.916;-2.995], p<0.001) were independently associated with persistent fatigue.Conclusion:Fatigue is a frequent and complex symptom in RA. Higher disease activity and greater disability are suggested as predictors of persistent fatigue.Disclosure of Interests:None declared

scholarly journals Part of pain labelled neuropathic in rheumatic disease might be rather nociplastic

RMD Open ◽  
2020 ◽  
Vol 6 (2) ◽  
pp. e001326
Author(s):  
Florian Bailly ◽  
Alain Cantagrel ◽  
Philippe Bertin ◽  
Serge Perrot ◽  
Thierry Thomas ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Rheumatic Diseases ◽  
Clinical Signs ◽  
Central Sensitisation ◽  
Small Fibre Neuropathy ◽  
Inflammatory Mechanism ◽  
Small Fibre ◽  
Inflammatory Drugs ◽  
The Right ◽  
Symptoms And Signs

Pain in rheumatic diseases is primarily due to mechanical or inflammatory mechanism, but neuropathic pain (NP) component is also occurring in many conditions and is probably underdiagnosed. The purpose of this article is to provide an overview of prevalence, pathophysiological and currently available treatment of NP in rheumatic diseases. When associated with clinical evaluation assessing neurological clinical signs and neuroanatomical distribution, Douleur Neuropathique 4 Questions, painDETECT, Leeds assessment of neuropathic symptoms and signs and Neuropathic Pain Questionnaire can detect NP component. Inflammatory or connective diseases, osteoarthritis, back pain or persistent pain after surgery are aetiologies that all may have a neuropathic component. Unlike nociceptive pain, NP does not respond to usual analgesics such as paracetamol and non-steroidal anti-inflammatory drugs. Entrapment neuropathy, peripheral neuropathy or small-fibre neuropathy are different aetiologies that can lead to NP. A part of the pain labelled neuropathic is rather nociplastic, secondary to a central sensitisation mechanism. Identifying the right component of pain (nociceptive vs neuropathic or nociplastic) could help to better manage pain in rheumatic diseases with pharmacological and non-pharmacological treatments.

scholarly journals AB0725 FACTORS ASSOCIATED WITH RADIOGRAPHIC SPINAL INVOLVEMENT IN SPONDYLOARTHRITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1657.2-1657
Author(s):  
M. Slouma ◽  
S. Rahmouni ◽  
R. Dhahri ◽  
I. Gharsallah ◽  
N. Boussetta ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Structural Damage ◽  
Disease Duration ◽  
Diagnostic Delay ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Positive Correlation ◽  
Factors Associated ◽  
The Mean

Background:Spondyloarthritis (SpA) is characterized by significant radiographic changes in the spine. The structural spine damage can be assessed using several scorings such as the Bath AS Radiology Index (BASRI) and the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS).Objectives:We aimed to identify factors associated with structural damage in the spine using these scores.Methods:We conducted a cross-sectional study including patients with SpA diagnosed according to the assessment of Spondyloarthritis International Society criteria.To assess the radiographic involvement of the spine, we used the mSASSS, the BASRI-spine (BASRI-S), the BASRI-lumber (BASRI-L) and the BASRI-cervical (BASRI-C).Disease activity was assessed using the BASDAI and ASDAS-CRP.Results:Among the 112 patients, 72.32% were men. The mean age was 43.78 ± 12,91 years. The mean age at diagnosis was 37.8 ± 13.45 years. The diagnostic delay of 37,8 ± 46 months.Forty-nine patients were smockers (43.8%).The mean BASDAI score and ASDAS–CRP score were 4.04 ± 1.99 and 3.30 ± 0.87.The mean ESR and CRP were 36.21 ± 27 (mm/H) and 31.28 ± 47.25 mg/LThe mean BASRI-S was 3,99 ± 21,96 and the mean mSASSS was 10,26 ± 15,41.Twenty-five patients (22.3%) had non-radiographic axial SpA.Men had higher BARSI-L (1.36 vs 0.7, p= 0.045) and BASRI-S (4.3 vs 3.09; p=0.047) than women.Moreover, smokers’ patients had higher mSASSS (14.07 vs 7.02; p=0.031), BASRI-C (1.23 vs 0.62; p=0.031), and BASRI-S (4.82 vs 3.35; p= 0.009) than nonsmokers’ patients.A positive correlation was noted between age and BASRI-C (r= 0.260, p=0.012). There was no correlation between age at the onset of SpA and structural spine damage.We found a positive correlation between disease duration and the following scores: BASRI-C (r=0.245, p=0.018) and BASRI-S (r=0.274, p=0.003).Patients with non-radiographic axial SpA had lower mSASSS (4.05 vs 12.14; p=0.034), BASRI-s (1.2 vs 4.9; p< 10-3), and BASRI-L (0.42 vs 1.4; p=0.003) than patients with radiographic axial SpA.There was no correlation between the radiographic index and BASDAI and ASDAS-CRP.Conclusion:We confirmed previous observations that male gender, smoking and disease duration are associated with structural damage in the spine [1].However, CRP and other inflammatory biomarkers were not associated with radiographic evidence of spine involvement.As observed in previous studies, the radiographic spine damage did not correlate with disease activity (BASDAI) [1].References:[1]Sari I, Haroon N. Radiographic Progression in Ankylosing Spondylitis: From Prognostication to Disease Modification. Curr Rheumatol Rep. 2018 Nov 8;20(12):82.Disclosure of Interests:None declared

scholarly journals Morphological Changes and Prognostic Factors before and after Photodynamic Therapy for Central Serous Chorioretinopathy

2021 ◽  
Vol 14 (1) ◽  
pp. 53
Author(s):  
Yu Wakatsuki ◽  
Koji Tanaka ◽  
Ryusaburo Mori ◽  
Koichi Furuya ◽  
Akiyuki Kawamura ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Photodynamic Therapy ◽  
Prognostic Factors ◽  
Central Serous Chorioretinopathy ◽  
Disease Duration ◽  
Morphological Changes ◽  
Factors Associated ◽  
Before And After ◽  
The Mean ◽  
Mean Luminance

Central serous chorioretinopathy (CSC) is a disease of unknown etiology, but half-dose photodynamic therapy (hPDT) is well known to be effective for CSC. Infrared reflectance (IR) has been shown to be effective for detecting retinal pigmented epithelial and choroidal lesions, but no reports have focused on chorioretinal changes using IR images after as compared to before hPDT. This study aimed to clarify the features of IR images as well as retinal and choroidal morphological changes before and after treatment with verteporfin hPDT for CSC. We also examined prognostic factors associated with CSC treatment. This was a retrospective study that included 140 eyes of 140 patients (male/female ratio 122:18, mean age 53.4 ± 10.8 years) diagnosed with CSC who underwent hPDT in our hospital during the period from April 2015 to December 2018. We determined changes in visual acuity, therapeutic efficacy, central retinal thickness (CRT), central choroidal thickness (CCT), and IR images at one and three months after hPDT as compared to before treatment. Dry macula was defined as a complete resolution of serous retinal detachment after hPDT. History of smoking, disease duration, presence of drusen, presence of retinal pigment epithelium abnormalities, type of fluorescein angiographic leakage, and presence of choroidal vascular hyperpermeability were investigated as prognostic factors associated with treatment efficacy. CRT and CCT were measured using optical coherence tomography (Spectralis HRA-2; Heidelberg Engineering), and IR images after versus before treatment were compared using ImageJ software (version 1.52) to calculate the mean luminance for a 3 × 3 mm area in the macula. Compared with the values before treatment, CCT, CRT, and visual acuity showed significant improvements at one and three months after treatment, and the mean luminance of IR images was also significantly increased. Furthermore, the luminance on IR images tended to rise, though the values at one month and three months after treatment did not differ significantly. Disease duration was significantly associated with dry macula one month after treatment, and visual acuity and CRT before hPDT were both significantly related to dry macula three months after treatment. IR images tended to improve over time, from before treatment through one and three months after hPDT.

Prevalence of hypovitaminosis D and impaired glucose tolerance in patients with neuroendocrine tumours undergoing somatostatin analogues therapy

2020 ◽  
Vol 74 (5) ◽  
pp. 410-414
Author(s):  
Lenka Nosáková ◽  
Peter Bánovčin ◽  
Rudolf Hyrdel ◽  
Miroslav Pindura ◽  
Peter Uhrík
Keyword(s):  
Vitamin D ◽  
Blood Glucose ◽  
Glucose Tolerance ◽  
Disease Duration ◽  
Somatostatin Analogs ◽  
Hypovitaminosis D ◽  
Somatostatin Analogues ◽  
Vitamin D Levels ◽  
High Prevalence ◽  
The Mean

Introduction: Neuroendocrine tumors of the gastrointestinal tract (GEP-NETs) are rare tumors representing a heterogeneous group of tumors. Somatostatin analogs (SSA) are commonly used in the palliative treatment of GEP-NETs. The aim of the study was to determine the potential side effects of SSA treatment. Methods and group of patients: The set consisted of patients undergoing the treatment with somatostatin analogues in an outpatient form. We evaluated the data about disease duration, SSA treatment, and type of SSA preparation. Subsequently, patients underwent vitamin D and blood glucose tests. Results: We evaluated a total of 16 patients (8 women and 8 men). The mean age was 61 years (43–82 years). Hypovitaminosis D was present in 13 patients (81.25%). Vitamin D levels ranged from 12.2 to 55.8 ng/ml. Glucose tolerance impairment was present in 44% of patients. Blood glucose ranged from 4.5 mmol/l to 7.6 mmol/l. Conclusion: Somatostatin analogues are generally considered as safe and well tolerated. In our work, we pointed to the relatively high prevalence of hypovitaminosis D and impaired fasting glucose.

scholarly journals Fatores associados à adesão de adultos/idosos ao tratamento da hipertensão arterial na atenção básica [Factors associated with adult/elderly adherence to the treatment of arterial hypertension in primary care] [Factores asociados con la adherencia de adultos/ancianos al tratamiento de la hipertensión arterial en atención primaria]

2019 ◽  
Vol 27 ◽  
pp. e45894
Author(s):  
Maria Emilia Marcondes Barbosa ◽  
Ellen Vanuza Martins Bertelli ◽  
Cristiane De Mello Aggio ◽  
Giovana Aparecida De Souza Scolari ◽  
Sonia Silva Marcon ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Quantitative Research ◽  
Cross Sectional ◽  
Factors Associated ◽  
Adherence Score ◽  
Sociodemographic Data ◽  
Significant Difference ◽  
The Mean ◽  
Basic Health Units ◽  
Structured Questionnaire

Objetivo: avaliar os fatores que influenciam na adesão de adultos/idosos ao tratamento de hipertensão arterial. Metodologia: pesquisa quantitativa transversal, realizada em duas Unidades Básicas de Saúde, no interior do Paraná, Brasil. Utilizou-se de questionário estruturado para obtenção dos dados sociodemográficos e escala do tipo likert de avaliação do tratamento, sendo a adesão atribuída à pontuação de 73 a 120. A análise foi a partir do software R. O escore de adesão foi descrito pela média, pelo desvio padrão e coeficiente de variação. Para associações entre a adesão ao tratamento, aplicou-se a regressão logística univariada. A pesquisa seguiu os preceitos éticos, obtendo aprovação CAAE: 61218216.8.0000.0106 e parecer Nº 1.838.418. Resultados: participaram do estudo 257 hipertensos, a maioria mulheres. Destes, 91,05% foram aderentes ao tratamento. Não houve diferença significativa entre as Unidades de Saúde. Conclusão: contribuíram para maior chance de adesão: idade superior a 60, aposentado e tempo diagnóstico superior a seis anos.ABSTRACTObjective: to evaluate the factors that influence the adherence of adults / elderly to the treatment of arterial hypertension. Methodology: cross-sectional quantitative research, carried out in two Basic Health Units in the interior of Paraná, in 2016. A structured questionnaire was used to obtain sociodemographic data and a likert scale for assessing treatment, with adherence attributed to a score of 73 to 120. The analysis was based on software R. The adherence score was described by the mean, standard deviation and coefficient of variation. For associations between treatment adherence, univariate logistic regression was used. The research followed the ethical precepts, obtaining CAAE approval: 61218216.8.0000.0106, opinion No. 1.838.418. Results: 257 hypertensive patients, mostly women, participated in the study. Of these, 91.05% were adherent to the treatment. There was no significant difference between the Health Units. Conclusion: They contributed to a greater chance of adherence, being over 60, retired and having been diagnosed for more than six years.RESUMENObjetivo: evaluar los factores que influyen en la adherencia de adultos / ancianos al tratamiento de la hipertensión arterial. Metodología: investigación cuantitativa transversal, llevada a cabo en dos Unidades Básicas de Salud en el interior de Paraná, Brasil, en 2016. Se utilizó de cuestionario estructurado para obtener datos sociodemográficos y escala likert para evaluar el tratamiento, con adherencia atribuida a puntuación de 73 a 120. El análisis se basó en el software R. La puntuación de adherencia se describió por la media, la desviación estándar y el coeficiente de variación. Para las asociaciones entre la adherencia al tratamiento, se utilizó la regresión logística univariada. La investigación siguió los preceptos éticos, obteniendo la aprobación del CAAE: 61218216.8.0000.0106, opinión No. 1.838.418. Resultados: 257 pacientes hipertensos, en su mayoría mujeres, participaron en el estudio. De estos, 91.05% se adhirieron al tratamiento. No hubo diferencias significativas entre las Unidades de Salud. Conclusión: contribuyeron a mayor probabilidad de adhesión: tener más de 60 años, retirarse y haber sido diagnosticados por más de seis años. 

scholarly journals Status of Gastrointestinal Nematode Infections and Associated Epidemiological Factors in Sheep From Córdoba, Colombia

2021 ◽  
Author(s):  
Elisa Brunal Tachack ◽  
Teresa Oviedo-Socarrás ◽  
Misael Oviedo Pastrana ◽  
Luis Carlos Pérez-Cogollo ◽  
Yonairo Herrera Benavides ◽  
...  
Keyword(s):  
Production Systems ◽  
Parasite Burden ◽  
Gastrointestinal Nematode ◽  
Gastrointestinal Nematodes ◽  
Economic Losses ◽  
Factors Associated ◽  
Mcmaster Technique ◽  
High Prevalence ◽  
The Mean ◽  
Sheep Production

Abstract Gastrointestinal nematodes cause serious economic losses in sheep production systems. To determine the prevalence and risk factors associated with these parasites, a study was conducted in 595 sheep in Córdoba, Colombia. Prevalence and parasite burden were determined using the McMaster technique. Larvae were cultured from feces to identify the nematode genera. For the analysis of associated factors and parasite burden, means, medians and confidence intervals were compared. A geo-referenced data analysis was performed and an epidemiological map was constructed. An overall prevalence of 88.2% was found, with the highest prevalence and parasite burden for Strongylida (83.2%) and Strongyloides (41%) nematodes. The mean parasite burden was 1255 eggs per gram. The gastrointestinal nematode genera identified were Trichostrongylus, Strongyloides, Haemonchus, Oesophagostomum, Bunostomum and Cooperia. In general, a significant association was found between parasite burden and dewormed animals, anthelmintic used, date of last deworming and breeds. The FAMACHA® method and body condition showed a significant association with Strongylida parasite burden. Clusters with higher intensity of gastrointestinal nematode burden and high prevalence were observed in the regions of Bajo Sinú, Sinú Medio and San Jorge.

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