scholarly journals Parallel and serial mediation analysis between pain, anxiety, depression, fatigue and nausea, vomiting and retching within a randomised controlled trial in patients with breast and prostate cancer

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e026809 ◽  
Author(s):  
Andreas Charalambous ◽  
Margarita Giannakopoulou ◽  
Evaggelos Bozas ◽  
Lefkios Paikousis
Keyword(s):  
Prostate Cancer ◽  
Side Effects ◽  
Indirect Effect ◽  
Randomised Control Trial ◽  
Anxiety And Depression ◽  
Home Setting ◽  
Pain Anxiety ◽  
Breast And Prostate Cancer ◽  
Anxiety Depression ◽  
The Relationship

ObjectiveCancer treatment is a particularly stressful period for the patient. The reasons vary and include fear of treatment outcome as well as treatment induced side effects. The patient frequently experiences simultaneously various side effects resulting in a diminishing of the patient’s health-related quality of life (HRQoL). The study provides evidence on the co-occurrence and inter-relations between pain, anxiety, depression and fatigue in patients with breast and prostate cancer.DesignThis paper presents a secondary analysis of the data from a randomised control trial designed to test the effectiveness of guided imagery and progressive muscle relaxation on pain, fatigue, anxiety and depression. Non-parametric bootstrapping analyses were used to test the mediational model of anxiety, fatigue and depression as parallel mediators of the relationship between pain and HRQoL.SettingThe study was undertaken at the home setting.ParticipantsIn total 208 patients were included in the study (assigned equally in two groups), referred at the outpatient clinics of the three participating cancer care centres.ResultsThe three mediators fully mediate the relationship between pain and HRQoL indirect effect (IEoverall=−0.3839, 95% CI: lower limit (LL)=−0.5073 to upper limit (UL)=−0.2825) indicating that patients with increased pain are likely to have higher levels of anxiety, fatigue and depression. Gender significantly moderated the mediational effect of Fatigue Index of Moderated Mediation (IMM=−0.2867 SE=0.1526, LL=−0.6127, UL=−0.0226) but did not moderate mediational effect of anxiety (IMM=−0.0709, SE=0.1414, LL=−0.3459, UL=+0.2089). The results show that the three mediators in a serial causal order fully mediate the relationship between pain and HRQoL (IEoverall=−0.384, 95% CI: LL=−0.51 to UL=−0.284) and the ratio of the overall indirect effect to the total effect is 0.8315 (95% CI: LL=0.5683 to UL=1.1718).ConclusionThis work provides evidence that targeting fatigue, anxiety and depression may have a meaningful effect on pain as a related symptom and potentially have a positive impact on HRQoL of patients with breast and prostate cancerTrial registration numberNCT01275872; Post-results.

Moderating Role of Stress, Anxiety, and Depression in the Relationship Between Tinnitus and Hearing Loss Among Patients

2020 ◽  
Vol 34 (4) ◽  
pp. 753-772
Author(s):  
Ammar Ahmed ◽  
Muhammad Aqeel ◽  
Tanvir Akhtar ◽  
Sammeen Salim ◽  
Bashir Ahmed
Keyword(s):  
Hearing Loss ◽  
Psychological Problems ◽  
Anxiety And Depression ◽  
Adaptation Level ◽  
Depression Anxiety Stress Scale ◽  
Neuropsychological Theory ◽  
Anxiety Depression ◽  
The Relationship ◽  
Moderating Role

Adaptation level theory of tinnitus and neuropsychological theory of tinnitus are extensively used frameworks for understanding emotional and psychological distress among tinnitus sufferers. Objective of the present study was to investigate potential associations between hearing loss, tinnitus, anxiety, depression, and stress. The Tinnitus Handicap Inventory (Newman, Jacobson, & Spitzer, 1996) and the Depression, Anxiety, Stress Scale (Lovibond & Lovibond, 1995)scales were administered to a sample of 110 tinnitus outpatients recruited from Audiology departments of Lahore and Rawalpindi hospitals. Results revealed tinnitus was positively linked with psychological problems. Additionally, it was established that tinnitus is a positive significant predictor for anxiety, stress and depression. The moderation models related to the interactions between psychological problems and hearing loss were negative significant predictors for tinnitus symptoms. Moreover, the comparative analysis between gender differences revealed a significant diversity in the levels of stress, anxiety, and depression. Results also elucidated that patients at initial stages of hearing loss were more prone towards reporting tinnitus symptoms along with emerging psychological problems.

scholarly journals How Is Sleep Related to Anxiety or Depression in Older Adults With Dementia?

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 619-619
Author(s):  
Yeji Hwang ◽  
Nancy Hodgson
Keyword(s):  
Anxiety And Depression ◽  
Regression Analyses ◽  
Subjective Sleep Quality ◽  
Subjective Sleep ◽  
Significant Relationships ◽  
People With Dementia ◽  
The Family ◽  
Study Participants ◽  
Anxiety Depression ◽  
The Relationship

Abstract Anxiety and depression are one of the most distressing symptoms for the family caregivers. Little is known about the relationship between sleep impairments and anxiety/depression in this population and how objective and subjective sleep measures differ in relation to anxiety. This study was designed to examine the relationship between sleep impairments and anxiety/depression in people with dementia, using both subjective and objective sleep measures. Among the 170 study participants, 50% (n=85) reported to have anxiety/depression. In univariate logistic regression analyses on anxiety/depression, adjusting for dementia stage, people with more subjective sleep impairment had higher odds of having anxiety/depression (OR=1.111; 95% CI: 1.020-1.211, p=0.016) and people with poorer subjective sleep quality had higher odds of having anxiety/depression (OR=1.702; 95% CI: 1.046-2.769, p=0.032). Objective sleep measures from actigraphy did not show any significant relationships to anxiety/depression. The results suggest that subjective sleep measures are closely related to anxiety/depression in this population.

Positive (But Not Negative) Punishment Predicts Anxiety and Depression Among Prostate Cancer Patients: An Exploration of the Behaviour Analytic Model of Depression

2009 ◽  
Vol 26 (4) ◽  
pp. 235-244 ◽  
Author(s):  
Vicki Bitsika ◽  
Christopher F. Sharpley ◽  
David R. H. Christie
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Anxiety And Depression ◽  
Powerful Predictor ◽  
Specific Population ◽  
Behavioural Interventions ◽  
Anxiety Depression ◽  
Gender Specific ◽  
Depression Disorder ◽  
Total Test

AbstractThe relative power of Positive and Negative Punishment as predictors of anxiety and depression was investigated within the gender-specific population of Prostate Cancer patients. As well as being a more powerful predictor of total test scores, Positive Punishment was also a stronger predictor of the presence of clinical levels of anxiety and depression. Examination of the particular Positive Punishment events that were significantly associated with clinical anxiety and depression showed considerable overlap, supporting the concept of a combined anxiety-depression disorder. Suggestions for behavioural interventions with this patient group are made.

The Relationship Between Communication Attitude, Anxiety, and Depression in Stutterers and Nonstutterers

1992 ◽  
Vol 35 (4) ◽  
pp. 789-798 ◽  
Author(s):  
Susan Miller ◽  
Ben C. Watson
Keyword(s):  
Trait Anxiety ◽  
Anxiety And Depression ◽  
General State ◽  
Severity Rating ◽  
Self Perceptions ◽  
Communication Situations ◽  
Negative Communication ◽  
State And Trait Anxiety ◽  
Anxiety Depression ◽  
The Relationship

People who stutter are frequently viewed as more anxious than nonstutterers and as being depressed. Further, a strong and pervasive stereotype is held by nonstutterers that people who stutter are guarded, nervous, and tense. This study examined self-perceptions of general state and trait anxiety, depression, and communication attitude in matched groups of stutterers and nonstutterers. Results refute the assertion that people who stutter are more anxious or depressed than those who do not. Anxiety and depression are not related to self-ratings of stuttering severity. Communication attitude is negative for this group of people who stutter and becomes increasingly negative as self-ratings of stuttering become more severe. People who stutter, grouped by severity rating, differed in the strength of the relation between measures of communication attitude, anxiety, and depression. Findings suggest that the anxiety of people who stutter is restricted to their attitude towards communication situations and that it is a rational response to negative communication experiences.

scholarly journals The Correlation of the Tinnitus Handicap Inventory with Depression and Anxiety in Veterans with Tinnitus

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Jinwei Hu ◽  
Jane Xu ◽  
Matthew Streelman ◽  
Helen Xu ◽  
O’neil Guthrie
Keyword(s):  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Multidisciplinary Intervention ◽  
Tinnitus Handicap Inventory ◽  
Hearing Status ◽  
Male Veterans ◽  
Positive Correlations ◽  
Anxiety Depression ◽  
The Relationship ◽  
Severe Tinnitus

Objective. The mechanisms of tinnitus are known to alter neuronal circuits in the brainstem and cortex, which are common to several comorbid conditions. This study examines the relationship between tinnitus and anxiety/depression.Subjects and Methods. Ninety-one male veterans with subjective tinnitus were enrolled in a Veterans Affairs Tinnitus Clinic. The Tinnitus Handicap Inventory (THI) was used to assess tinnitus severity. ICD-9 codes for anxiety/depression were used to determine their prevalence. Pure tone averages (PTA) were used to assess hearing status.Results. Descriptive analyses revealed that 79.1% of the 91 tinnitus sufferers had a diagnosis of anxiety, 59.3% had depression, and 58.2% suffered from both anxiety/depression. Patients with anxiety had elevated total THI scores as compared to patients without anxiety (p<0.05). Patients with anxiety or depression had significantly increased Functional and Emotional THI scores, but not Catastrophic THI score. Significant positive correlations were illustrated between the degree of tinnitus and anxiety/depression (p<0.05). There were no differences in PTA among groups.Conclusions. A majority of patients with tinnitus exhibited anxiety and depression. These patients suffered more severe tinnitus than did patients without anxiety and depression. The data support the need for multidisciplinary intervention of veterans with tinnitus.

scholarly journals Acute Relationship between Cognitive and Psychological Symptoms of Patients with Mild Traumatic Brain Injury

2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
Elaine de Guise ◽  
Joanne LeBlanc ◽  
Simon Tinawi ◽  
Julie Lamoureux ◽  
Mitra Feyz
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Function ◽  
Psychological Symptoms ◽  
Anxiety And Depression ◽  
Psychological Reactions ◽  
Postconcussive Symptoms ◽  
High Level ◽  
Anxiety Depression ◽  
The Relationship ◽  
Very High

Objective. The goal of this study was to explore the relationship between acute psychological reactions and cognition as well as postconcussive symptoms in patients with MTBI. Research Methods. Sociodemographic and medical history data were gathered for 59 patients diagnosed with MTBI. Validated and standardized tools were used to assess anxiety, depression, and cognitive function two weeks after trauma. Postconcussive symptoms were assessed with the Rivermead postconcussive questionnaire. Results. Despite the absence of significant neuropsychological deficits, a very high level of anxiety and depression was observed in our cohort. Level of anxiety and depression were positively related to cognitive performances and to postconcussive symptoms. Moreover, patients with preexisting alcohol and psychological problems were more likely to present with acute depression after MTBI. Conclusions. Early psychological rehabilitation should be provided to decrease the intensity and frequency of postconcussive symptoms and diminish the risk of these problems becoming chronic.

scholarly journals Obesity, Anxiety, Depression and Sexual Desire: A Study on a Sample of Obese Patients

2016 ◽  
Vol 9 (1) ◽  
pp. 99-99
Author(s):  
M. Colombo ◽  
◽  
P. Zeppegno ◽  
F. D’Andrea ◽  
E. Torre ◽  
...  
Keyword(s):  
Sexual Desire ◽  
Anxiety And Depression ◽  
Obese Patients ◽  
Male And Female ◽  
Sociodemographic Data ◽  
Sex Drive ◽  
Low Levels ◽  
Main Components ◽  
Anxiety Depression ◽  
The Relationship

Objective: Evaluate the presence of anxiety and depression in a group of male and female patients, either overweight or obese, after a first medical examination at the dietetics dept. at Ospedale Maggiore in Novara. Evaluate sexual desire both in autoerotism and in a couple situations. Evaluate the relationship between sexual desire, anxiety and depression. Evaluate the perception patients have of their body and the presence of anger (state and trait) analyzing its main components. Design and Method: 100 patients were included in the study. The study protocol consists of: sociodemographic data, HADS, Sexual Desire Inventory, BC Scale and STAXI 2. Results: The levels of anxiety, depression and dissatisfaction on every patient’s body are elevated. There was evidence of low levels of sexual desire in the female sample and normal levels in men. There were no statistically significant associations between depression, anxiety and low sex drive. In both sexes there is a tendency to control the rage within. Men mostly express rage verbally while women express it physically. Conclusions: Proper nutrition is helpful to sexuality and mood.

scholarly journals Application of hypnosis in psychOncology: A review of the literature

2021 ◽  
Vol 39 (2) ◽  
pp. 263-275
Author(s):  
Sónia Remondes-Costa ◽  
Filipa Magalhães ◽  
Inês Martins ◽  
André Louro ◽  
Martim Santos ◽  
...  
Keyword(s):  
Side Effects ◽  
Cancer Patients ◽  
Web Of Science ◽  
Controlled Trials ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Cancer Disease ◽  
Pain Anxiety ◽  
Randomized Controlled ◽  
Anxiety Depression

Hypnosis is useful for multiple somatic and psychological disorders, particularly cancer disease-related issues. In fact, the literature points out that hypnosis is effective in helping patients deal with aspects disease related, as well as in reducing the side effects of treatment. This review of the literature aims to summarize and assess the evidence of the usefulness of hypnosis in cancer patients and was conducted based on articles published between 2012 and 2019. The databases used were: B-on, SciELO, MEDLINE, and Web of Science. Randomized controlled trials and non-randomized studies were assessed. Among 837 studies identified, nine met the inclusion criteria and were selected. The studies were consensual to the effectiveness of hypnosis in reducing a set of symptoms in cancer patients, mainly pain, anxiety, depression, fatigue, and insomnia. However, several methodological limitations were identified. The practice of hypnosis is related to a significant number of techniques and approaches that differ from each other, thus compromising the interpretation and generalization of its effects. This review updates the evidence and suggests that the study of the efficacy of hypnosis in cancer patients is still limited. Further research into the effectiveness and acceptability of hypnosis for cancer patients is recommended.

scholarly journals Influential Factors on Sexual Function in Infertile Women with Endometriosis: A Path Analysis

2020 ◽  
Author(s):  
samaneh youseflu ◽  
Shahideh Jahanian Sadatmahalleh ◽  
Mahnaz Bahri Khomami ◽  
Malihe Nasiri
Keyword(s):  
Physical Activity ◽  
Sleep Quality ◽  
Sexual Function ◽  
Pelvic Pain ◽  
Indirect Effect ◽  
Sexual Life ◽  
Anxiety And Depression ◽  
Infertile Women ◽  
Anxiety Depression

Abstract Background: Endometriosis have a negative influence on women’s sexual life. The aim of the current study was to test a conceptual model considering the interrelated role of anxiety, depression, sleep quality, physical activity, BMI, stage of endometriosis, the intensity of dyspareunia and pelvic pain on sexual function (SF) in infertile women with endometriosis. Also test the mediating role of sleep quality, anxiety, and depression.Method: In the present cross-sectional study, 220 infertile women with a laparoscopically confirmed endometriosis were recruited. Data were collected using a socio-demographic checklist, Female Sexual Function Index (FSFI), Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS), Visual Analog Scale (VAS). Results: We found that anxiety, depression, sleep quality, BMI, level of education, stage of endometriosis, and dyspareunia have a direct effect on women’s SF. In our study, sleep quality, anxiety, pelvic pain, and depression were the four major mediators that the higher scores lead to a decrease in the SF of endometriosis patients. The intensity of pelvic pain with an effect on sleep quality (SQ) and dyspareunia change women’s SF. The lower level of physical activity, and higher BMI with indirect effect thorough anxiety, and SQ can worsen SF. Also, a higher level of anxiety leads to poor SQ and depression. Anxiety with both direct and indirect effect impress women’s SF.Conclusion: It seems that the main risk factors for sexual dysfunction in women with endometriosis are higher rates of anxiety, depression, poor sleep quality, pelvic pain, and dyspareunia. In the care of women with endometriosis, not only laparoscopy and medical treatment should be performed but also psychotherapeutic and psychosexual help should be offered.

scholarly journals Anxiety, depression and quality of life in mothers of intellectually disabled children

2018 ◽  
Vol 6 (2) ◽  
pp. 28-35
Author(s):  
N Sapkota ◽  
A K Pandey ◽  
BK Deo ◽  
MK Shrivastava
Keyword(s):  
Quality Of Life ◽  
Intellectual Disability ◽  
Poor Quality ◽  
Anxiety And Depression ◽  
Disabled Children ◽  
Intellectually Disabled ◽  
Icd 10 ◽  
Anxiety Depression ◽  
The Relationship

Introduction: Studies have shown that there is an association between Anxiety, Depression in mothers of children having Intellectual disability with poor quality of life (QOL) in mothers of such children. This study was carried with the objectives to describe the clinico-socio-demographic profile of mothers of intellectually disabled children and to investigate the relationship among anxiety and depression with quality of life in mothers with intellectually disabled children.Material And Method: Mothers (N=31), whose children's IQ score was below 70, were enrolled in to the study with their informed consent. Depression and Anxiety disorders were diagnosed as per ICD 10. Severity of depression was measured with BDI and Anxiety symptoms with STAI. WHOQOL-BREF was used to assess Quality of life. The relationship among anxiety, depression and QOL were analysed using diagonal matrix, ANOVA and Pearson correlation test.Results: The mean age of participants was 50.23 (S.D= 6.11), BDI score was 13.65(S.D= 11.301), STAI score was 53.90 (SD= 15.821), WHOQOL- BREF in all four domains was 290.90 (S.D=49.42). There was significant correlation between BDI and STAI (P=0.01, r:0.651 ) and the three domains of WHOQOL- BREF(P=0.01, r:0.821, 0.843, 0.635 respectively) scale except Environment domain. Among the participants, 48.4% (ICD 10) had depression of varying degree along with 54.8% depression as per BDI cut off score. Anxiety disorder was seen in 22.6% as per ICD 10 but as per STAI it was 53.90(SD=15.821) which was statistically significant (p:0.01, r: -0.507). Depression when compared with no diagnosis persons has poor quality of life in WHOQOL-BREF physical domain (p:0.002) but with compared to Anxiety or both it was not statistically significant.Conclusion: The findings of this study revealed that mothers of children having Intellectual disability have high level of Anxiety and Depression which indeed had impact in quality of life. J Psychiatrists’ Association of Nepal Vol. 6, No. 2, 2017 Page: 28-35

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