scholarly journals Endurance and resistance training lowers C-reactive protein in young, healthy females

2011 ◽  
Vol 36 (5) ◽  
pp. 660-670 ◽  
Author(s):  
Laura A. Daray ◽  
Tara M. Henagan ◽  
Michael Zanovec ◽  
Conrad P. Earnest ◽  
Lisa G. Johnson ◽  
...  
Keyword(s):  
Body Composition ◽  
Resistance Training ◽  
Body Fat ◽  
Aerobic Capacity ◽  
C Reactive Protein ◽  
Young Females ◽  
Marathon Training ◽  
Reactive Protein ◽  
Body Strength ◽  
Additional Resistance

The purpose of this study was to determine whether endurance (E) or endurance + resistance (ER) training affects C-reactive protein (CRP) and if these changes are related to alterations in fitness and (or) body composition in young females. Thirty-eight females (aged 18–24 years) were assigned to 1 of 3 groups: (1) E, (2) ER or (3) active control (AC). The E and ER groups completed 15 weeks of marathon training. The ER group performed additional resistance training and the AC group maintained their usual exercise routine. Primary outcomes were measured pre- and post-training and included anthropometric indices, dual-energy x-ray absorptiometry, plasma CRP, time to complete 1.5 miles (in minutes), and upper and lower body strength tests (i.e., 8 repetition max on bench and leg press (ER group only)). There were no differences in any variable among the groups at baseline. After training, the E group decreased time to complete 1.5 miles (p < 0.05). The AC group decreased percent and absolute body fat while the E group decreased percent body fat, absolute body fat, and android and gynoid body fat (p < 0.05). The ER group significantly improved strength (p < 0.001) and reduced plasma CRP from 2.0 ± 1.1 to 0.8 ± 0.3 mg·L–1 (p = 0.03). No significant associations were observed between CRP and measures of body composition or aerobic capacity. Combined endurance and resistance training may be an effective modality for reducing plasma CRP in young adult females independent of changes in aerobic capacity or body composition.

scholarly journals The Effects of Low-Energy Moderate-Carbohydrate (MCD) and Mixed (MixD) Diets on Serum Lipid Profiles and Body Composition in Middle-Aged Men: A Randomized Controlled Parallel-Group Clinical Trial

2020 ◽  
Vol 17 (4) ◽  
pp. 1332 ◽  
Author(s):  
Małgorzata Magdalena Michalczyk ◽  
Adam Maszczyk ◽  
Petr Stastny
Keyword(s):  
Body Composition ◽  
Muscle Mass ◽  
Body Mass ◽  
Body Fat ◽  
Density Lipoprotein ◽  
Low Energy ◽  
C Reactive Protein ◽  
Middle Aged ◽  
Reactive Protein ◽  
Body Fat Content

Carbohydrate-restricted diets have become very popular due to their numerous health benefits. The aim of this study was to determine the influence of 4 weeks of a well-planned, low-energy moderate-carbohydrate diet (MCD) and a low-energy mixed diet (MixD) on the lipoprotein profile, glucose and C-reactive protein concentrations, body mass, and body composition in middle-aged males. Sixty middle-aged males were randomly assigned to the following groups: hypocaloric MCD (32% carbohydrates, 28% proteins, and 40% fat), hypocaloric MixD (50% carbohydrates, 20% proteins, and 30% fat), and a conventional (control) diet (CD; 48% carbohydrates, 15% proteins, and 37% fat). The participants who were classified into the MCD and MixD groups consumed 20% fewer calories daily than the total daily energy expenditure (TDEE). Baseline and postintervention fasting triacylglycerol (TG), LDL (low-density lipoprotein) cholesterol (LDL-C), HDL (high-density lipoprotein) cholesterol (HDL-C), total cholesterol (tCh), glucose (Gl), and C-reactive protein were evaluated. Body mass (BM) and body composition changes, including body fat (BF), % body fat (PBF), and muscle mass (MM), were monitored. Compared with MixD and CD, MCD significantly changed the fasting serum concentrations of TG (p < 0.05), HDL-C (p < 0.05), LDL-C (p < 0.05), tCh (p < 0.05), and glucose (p < 0.01). Additionally, body fat content (kg and %) was significantly reduced (p < 0.05) after MCD compared with MixD and CD. After the MixD intervention, BM and MM decreased (p < 0.05) compared with baseline values. Compared with baseline, after the MixD, BM, MM, tCh, LDL-C, and TG changed significantly. The 4 week low-energy MCD intervention changed lipoproteins, glucose, and body fat to a greater extent than the low-energy MixD. A hypocaloric MCD may be suggested for middle-aged male subjects who want to lose weight by reducing body fat content without compromising muscle mass.

Synergism Effects of Ursolic Acid Supplementation on the Levels of Irisin, C-reactive Protein, IL-6, and TNF-α During High-intensity Resistance Training in Low Activity Men

2020 ◽  
Vol 20 (2) ◽  
pp. 138-144 ◽  
Author(s):  
Ehsan Asghari ◽  
Amir Rashidlamir ◽  
Seyyed R.A. Hosseini ◽  
Mahtab Moazzami ◽  
Saeed Samarghandian ◽  
...  
Keyword(s):  
Resistance Training ◽  
Ursolic Acid ◽  
High Intensity ◽  
Plasma Levels ◽  
Group Versus ◽  
Current Data ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Tnf Α ◽  
Low Activity

Background:: Ursolic Acid (UA) is a pentacyclic triterpenoid carboxylic acid which is extracted from plants. UA may enhance the effect of Resistance Training (RT) in human. Objective: Current research was designed to show the effect of High-Intensity Resistance Training (HIRT) in the presence or absence of UA on the serum levels of irisin, CRP, IL-6 and TNF-α in the low activity men. Method:: The study included twenty-two healthy male HIRT with placebo, supplementation, and HIRT in the presence of UA supplementation. The two groups received eight-week intervention including 2 sets of 8 exercises, with 8~10 repetitions at 70~75% of 1 repetition maximum and a 2 min rest interval between sets, performed 3 times/week. Placebo or UA orally was evaluated as 1 capsule 3 times/day during 8 weeks. The subsequent factors were measured post- and preintervention: C-Reactive Protein (CRP), Irisin, Tumor Necrotic Factor (TNF-α) and Interleukin-6 (IL-6). Results:: UA supplementation significantly increased the plasma levels of irisin in the HIRT+UA group versus the HIRT+P group (p<0.05). UA treatment also dramatically decreased the plasma levels of CRP, IL-6, and TNF-α in the HIRT+UA group versus the HIRT+P group (p<0.05). Conclusion:: The current data showed that UA-induced an increase in serum irisin and reduction of CRP, IL-6, and TNF-α may have beneficial effects as a chemical for increasing of the effects of HIRT in low activity men.

scholarly journals The association of parameters of body composition and laboratory markers with the severity of hypertriglyceridemia-induced pancreatitis

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Lifang Chen ◽  
Yingbao Huang ◽  
Huajun Yu ◽  
Kehua Pan ◽  
Zhao Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Composition ◽  
Adipose Tissue ◽  
Serum Albumin ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Apolipoprotein A ◽  
Laboratory Markers ◽  
Subcutaneous Adipose ◽  
Low Serum

AbstractBackgroundHypertriglyceridemia has arisen as the third leading cause of acute pancreatitis. This study aimed at exploring the association between the severity of hypertriglyceridemia-induced pancreatitis (HTGP) and computed tomography (CT)-based body composition parameters and laboratory markers.MethodsLaboratory and clinical parameters were collected from 242 patients with HTGP between 2017 and 2020. Severity of HTGP was evaluated by original or modified CT severity index. Body composition parameters such as area and radiodensity of muscle, subcutaneous adipose tissue and visceral adipose tissue were calculated by CT at the level of third lumbar vertebra. Parameters were compared between mild and moderately severe to severe HTGP. Uni-variate and multi-variate Logistic regression analyses were employed to assess the risk factors of the severity of HTGP.ResultsSeventy patients (28.9%) presented with mild HTGP. Body mass index, waist circumference and all CT-based body composition parameters differed between male and female patients. None was associated with the severity of HTGP, neither in males nor in females. Receiver operating characteristic curves showed that areas under the curves of apolipoprotein A-I and albumin to predict the severity of HTGP were 0.786 and 0.759, respectively (allP < 0.001). Uni-variate and further multi-variate Logistic regression analysis confirmed that low serum albumin (< 35 g/L,P = 0.004, OR = 3.362, 95%CI = 1.492–8.823) and apolipoprotein A-I (< 1.1 g/L,P < 0.001, OR = 5.126, 95%CI = 2.348–11.195), as well as high C-reactive protein (> 90 mg/L,P = 0.005, OR = 3.061, 95%CI = 1.407–6.659) and lipase (P = 0.033, OR = 2.283, 95%CI = 1.070–4.873) were risk factors of moderately severe to severe HTGP. Levels of albumin, apolipoprotein A-I, C-reactive protein and lipase were also associated with the length of hospital stay (allP < 0.05). Besides, low serum albumin, low-density lipoprotein cholesterol and high radiodensity of subcutaneous adipose tissue were significant risk factors of pancreatic necrosis in patients with HTGP (allP < 0.05).ConclusionsLow serum albumin and apolipoprotein A-I, and high C-reactive protein and lipase upon admission were associated with a more severe type of HTGP and longer hospital stay for these patients. Albumin and apolipoprotein A-I may serve as novel biomarkers for the severity of HTGP. However, none of the body composition parameters was associated with the severity of HTGP.

scholarly journals C-reactive protein is inversely and independently associated with maximal oxygen uptake in adolescents with obesity

2020 ◽  
Vol 34 (3) ◽  
pp. 463-469
Author(s):  
João Elias Dias Nunes ◽  
Heitor Santos Cunha ◽  
Renata Roland Teixeira ◽  
Foued S. Espindola ◽  
Nádia Carla Cheik
Keyword(s):  
Body Composition ◽  
Cardiorespiratory Fitness ◽  
Fat Body ◽  
High Sensitivity ◽  
Bioelectrical Impedance ◽  
Tnf Alpha ◽  
Maximum Oxygen Consumption ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Control Plasma

The purposes of this study were: 1) investigate whether different markers of infl ammation (CRP and TNF-alpha) are correlated to cardiorespiratory fi tness in adolescents with obesity; 2) examine the association of these variables when adjusted by parameters of body composition. Were selected 57 individuals, 34 girls and 23 boys, with 16.4±1.56 years and body mass index 36.0±4.3 kg/m2. Anthropometric measurements (weight, height and abdominal circunference) and body composition (BMI, visceral fat, body fat) were assessment. Body composition was estimated by analyzer of tetrapolar bioelectrical impedance. Obesity was defi ned as BMI>95th percentile of the curve proposed by the Center for Diseases Control. Plasma TNF-alpha was measured by a quantitative two-site high-sensitivity enzyme immunoassay and CRP was measured by high-sensitivityimmunoturbidimetric assay. Graded maximal exercise testing was performed to obtain the maximum oxygen consumption (VO2max) and velocity associated with the VO2max (vVO2max). Signifi cant correlations of CRP with VO2max and vVO2max were found (r=-0.40 and r=-0,36, respectively). No correlations were observed between TNF-alpha and VO2max e vVO2max. CRP was associated to the VO2max and vVO2max independently of measurements of body composition. The CRP was independently and inversely associated with direct measurement of VO2max and the indirect variable of cardiorespiratory fitness vVO2max, in obese adolescents, even after adjustments in body composition, a potential confounding factor. No association was found between TNF-alpha and the parameters of cardiorespiratory fitness.

Factors associated with baseline and serial changes in circulating NT-proBNP and high-sensitivity cardiac troponin T in a population-based cohort (Dallas Heart Study)

2021 ◽  
Author(s):  
Christopher W Puleo ◽  
Colby R Ayers ◽  
Sonia Garg ◽  
Ian J Neeland ◽  
Alana A Lewis ◽  
...  
Keyword(s):  
Body Composition ◽  
Cardiac Troponin ◽  
Troponin T ◽  
High Sensitivity ◽  
Left Ventricular ◽  
Cardiac Troponin T ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Heart Study ◽  
Dallas Heart Study

Aim: N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin T (hs-cTnT) associate with structural heart disease and heart failure risk in individuals without known cardiovascular disease (CVD). However, few data are available regarding whether factors influencing levels of these two biomarkers are similar or distinct. We performed serial measurement of NT-proBNP and hs-cTnT in a contemporary multiethnic cohort with extensive phenotyping, with the goal of identifying their respective biological determinants in a population without known or suspected CVD. Methods: We evaluated 1877 participants of the Dallas Heart Study who had NT-proBNP and hs-cTnT measured and were free from clinical CVD at the each of its two examinations (2000–2002 and 2007–2009). Variables collected included demographic and risk factors, high-sensitivity C-reactive protein, body composition via dual-energy x-ray absorptiometry, coronary artery calcium by computed tomography, and cardiac dimensions and function by cardiac MRI. Linear regression was used to identify associations of these factors with each biomarker at baseline and with changes in biomarkers over follow-up. Results: NT-proBNP and hs-cTnT were poorly correlated at baseline (Spearman rho 0.083, p = 0.015), with only moderate correlation between change values (rho 0.18, p < 0.001). hs-cTnT positively associated and NT-proBNP inversely associated with male gender and black race. At baseline, both NT-proBNP and hs-cTnT associated with left ventricular end-diastolic volume and wall thickness, but only NT-proBNP associated with left atrial size. Changes in cardiac dimensions between phases were more strongly associated with changes in NT-proBNP than hs-cTnT. NT-proBNP was more strongly associated with high-sensitivity C-reactive protein and measures of body composition than hs-cTnT. Conclusion: Among individuals without CVD in the general population, NT-proBNP and hs-cTnT are nonredundant biomarkers that are differentially associated with demographic and cardiac factors. These findings indicate that hs-cTnT and NT-proBNP may reflect different pathophysiological pathways.

The Effects of a 20-Week Exercise Training Program on Resting Metabolic Rate in Previously Sedentary, Moderately Obese Women

2001 ◽  
Vol 11 (1) ◽  
pp. 15-31 ◽  
Author(s):  
Heidi K. Byrne ◽  
Jack H. Wilmore
Keyword(s):  
Resistance Training ◽  
Exercise Training ◽  
Metabolic Rate ◽  
Training Program ◽  
Body Fat ◽  
Aerobic Capacity ◽  
Resting Metabolic Rate ◽  
Fat Free Mass ◽  
Obese Women ◽  
Resistance Training Program

The present study was designed to investigate the effects of exercise training on resting metabolic rate (RMR) in moderately obese women. It was hypothesized that exercise training would increase resting metabolic rate. Nineteen previously sedentary, moderately obese women (age = 38.0 ± 0.9 years, percent body fat = 37.5 ± 0.8) trained for 20 weeks using either resistance training (RT) or a combination of resistance training arid walking (RT/W). The high intensity resistance training program was designed to increase strength and fat-free mass and the walking program to increase aerobic capacity. There was also a non-exercising control group (C) of 9 subjects in this study. Fat-free mass was significantly increased in both the RT (+1.90 kg) and RT/W (+1.90 kg) groups as a result of the training program. No group showed significant changes in fat mass or relative body fat from pre- to post-training. Aerobic capacity was slightly, though significantly, increased in the RT/W group only. The RT group showed a significant increase (+44 kcal · day−1), while the RT/W group showed a significant decrease (-53 kcal · day−1) in resting metabolic rate post-training. RT can potentiate an increase in RMR through an increase in fat-free mass, and the decrease in RMR in the RT/W group may have been a result of heat acclimation from the walk training.

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