The development of the hypothalamo–pituitary axis in the neonatal rat: pituitary and serum prolactin concentrations

1977 ◽  
Vol 55 (1) ◽  
pp. 84-89 ◽  
Author(s):  
J. H. Dussault ◽  
P. Walker ◽  
J. D. Dubois

Using highly specific double-antibody radioimmunoassay techniques, we have measured pituitary and serum prolactin (PRL) concentrations in neonatal rats from birth to 60 d. Pituitary PRL concentration was low at birth in both sexes and peak prepuberal values were attained at 25–28 d. Following this time, pituitary PRL concentrations in females were significantly higher than those observed in males (p < 0.01). Serum PRL concentrations were low at birth in both sexes and remained low until 15 d, when they rose to peak values just before puberty. There were no significant sex differences with respect to serum PRL concentrations. These data indicate that hypothalamic control of PRL secretion develops during the neonatal period of the rat. The relationship of this developmental process in the neonatal rat as a possible model for the study of the midgestational hypothalamic maturation of the human fetus is discussed.

1990 ◽  
Vol 18 (1) ◽  
pp. 41-51 ◽  
Author(s):  
Gary G. Ford ◽  
Mary E. Procidano

The previously unexplored relationship of self-actualization to life stress and perceived social support from family and from friends was investigated. Measures of all variables were administered to 54 female and 52 male adult undergraduate students (age range of 18–81 years). The relationship of each variable to psychological adjustment (depression) also was assessed. As predicted, correlational results revealed self-actualization to be related positively to perceived social support and inversely to depression and life stress. Social support was inversely related to depression, and life stress was related positively to depression. Significant sex differences discovered in the relationship of self-actualization to perceived social support are discussed in terms of possible sex differences in the developmental process of self-actualization.


2003 ◽  
Vol 19 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Gisli H. Gudjonsson ◽  
Jon Fridrik Sigurdsson

Summary: The Gudjonsson Compliance Scale (GCS), the COPE Scale, and the Rosenberg Self-Esteem Scale were administered to 212 men and 212 women. Multiple regression of the test scores showed that low self-esteem and denial coping were the best predictors of compliance in both men and women. Significant sex differences emerged on all three scales, with women having lower self-esteem than men, being more compliant, and using different coping strategies when confronted with a stressful situation. The sex difference in compliance was mediated by differences in self-esteem between men and women.


1980 ◽  
Vol 29 (1) ◽  
pp. 25-34 ◽  
Author(s):  
JOAN DANIELS PEDRO ◽  
PATRICIA WOLLEAT ◽  
ELIZABETH FENNEMA

Sex Roles ◽  
1984 ◽  
Vol 11 (7-8) ◽  
pp. 719-734 ◽  
Author(s):  
Nancy Eisenberg ◽  
Karlsson Roth ◽  
Karyl A. Bryniarski ◽  
Edward Murray

2021 ◽  
Author(s):  
Lea L. Backhausen ◽  
Juliane H. Froehner ◽  
Herve Lemaitre ◽  
Eric Artiges ◽  
Marie-Laure Paillere-Martinot ◽  
...  

Adolescent subcortical structural brain development might underlie psychopathological symptoms, which often emerge in adolescence. At the same time, sex differences exist in psychopathology, which might be mirrored in underlying sex differences in structural development. However, previous studies showed inconsistencies in subcortical trajectories and potential sex differences. Therefore, we aimed to investigate the subcortical structural trajectories and their sex differences across adolescence using for the first time a single cohort design, the same quality control procedure, software and a general additive mixed modeling approach. We investigated two large European sites from ages 14 to 24 with 503 participants and 1408 total scans from France and Germany as part of the IMAGEN project including four waves of data acquisition. We found significantly larger volumes in males versus females in both sites and across all seven subcortical regions. Sex differences in age-related trajectories were observed across all regions in both sites. Our findings provide further evidence of sex differences in longitudinal adolescent brain development of subcortical regions and thus might eventually support the relationship of underlying brain development and different adolescent psychopathology in boys and girls.


1977 ◽  
Vol 55 (5) ◽  
pp. 1091-1097 ◽  
Author(s):  
J. H. Dussault ◽  
P. Walker ◽  
J. D. Dubois ◽  
F. Labrie

Using specific radioimmunoassay techniques, we have measured hypothalamic LHRH concentration and pituitary and serum LH and FSH concentrations in neonatal rats from 0 to 60 days after birth. There were no sex differences demonstrable for hypothalamic LHRH concentration, which rose from minimal values at 2 days to peak concentrations at 22–28 days and declined significantly with the approach of puberty. Pituitary LH concentration in the two sexes rose to peak values at 19–25 days, with significantly higher values observed in females (p < 0.01). Serum LH concentration was high in both sexes at birth, the values in females being significantly higher than those observed in males (p < 0.01). While the serum LH concentration remained relatively stable throughout the study period in males, it declined rapidly to a nadir at 28 days in females. Pituitary FSH concentration was low at birth in both sexes. Females demonstrated a marked rise to peak concentrations at 16 days while males achieved significantly lower peak prepuberal values (p < 0.01) at 28 days. Serum FSH concentration was significantly higher in females (p < 0.01) at birth and rose further to peak values at 16 days. Males attained peak serum FSH concentrations at 35 days. These data demonstrate that the maturation of the hypothalamo–pituitary–gonadal axis develops in the neonatal period in the rat and confirm the presence of significant differences in hypothalamic sexual differentiation and control. The possibility of this developmental process in the neonatal rat as a model for the study of the midgestational hypothalamic maturation of the human foetus is discussed.


1968 ◽  
Vol 22 (2) ◽  
pp. 547-554 ◽  
Author(s):  
Jan W. Kakolewski ◽  
Verne C. Cox ◽  
Elliot S. Valenstein

Data are presented to demonstrate that the effects of gonadectomy on body weight and food consumption differ in male and female rats. The findings are related to the authors' report of sex differences in the effects of ventromedial hypothalamic damage. A review of the literature on the relationship of the gonads to body weight in different species is presented.


1977 ◽  
Vol 1 (3) ◽  
pp. 229-246 ◽  
Author(s):  
Rebecca Oxford Manley

This article is a critical review of studies concerning the relationship of parental warmth and hostility to sex-related differences in children's achievement orientation. Parental warmth seemed to operate differently upon girls' and boys' achievement orientation in most of the studies cited. Moderate but not high maternal warmth and even slight hostility were related to strong achievement∗ orientation in girls, while high maternal nurturance and affection were associated with strong achievement orientation in boys. However, the article warns against assuming a simple causal relationship between parental warmth and sex-related differences in children's achievement orientation. Achievement theories, two main parental dimensions, and future research directions are also discussed.


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