Projected research trends in invertebrate physiology and biochemistry

1987 ◽  
Vol 65 (4) ◽  
pp. 797-802
Author(s):  
Roger G. H. Downer
Keyword(s):  
Rational Design ◽  
Research Progress ◽  
Future Research ◽  
Invertebrate Species ◽  
Research Areas ◽  
Modern Molecular Biology ◽  
Highly Sensitive ◽  
Physiology And Biochemistry ◽  
Invertebrate Physiology ◽  
Increased Activity

The direction of future research is likely to be influenced by major conceptual advances and technological breakthroughs, neither of which can be predicted with certainty. However, it is possible to identify general areas in which conceptual advances may be anticipated as a result of studies on invertebrate physiology and biochemistry and, in this regard, neurobiology and developmental biology offer particular promise. It is reasonable to predict also that the technologies of modern molecular biology and the development of highly sensitive analytical instrumentation will greatly facilitate research progress. Increased activity may also be predicted in strategic research areas including those that will lead to the rational design of pesticides and the improvement of "farming" procedures for invertebrate species that are used as sources of food. Invertebrates are also expected to continue to be used as models for biomedical research.

scholarly journals Industry 4.0 Technologies for Manufacturing Sustainability: A Systematic Review and Future Research Directions

2021 ◽  
Vol 11 (12) ◽  
pp. 5725
Author(s):  
Anbesh Jamwal ◽  
Rajeev Agrawal ◽  
Monica Sharma ◽  
Antonio Giallanza
Keyword(s):  
Industry 4.0 ◽  
Industrial Revolution ◽  
Big Data Analytics ◽  
Research Progress ◽  
Smart Manufacturing ◽  
Future Research ◽  
Business Practices ◽  
Research Directions ◽  
Research Areas ◽  
Future Research Directions

Recent developments in manufacturing processes and automation have led to the new industrial revolution termed “Industry 4.0”. Industry 4.0 can be considered as a broad domain which includes: data management, manufacturing competitiveness, production processes and efficiency. The term Industry 4.0 includes a variety of key enabling technologies i.e., cyber physical systems, Internet of Things, artificial intelligence, big data analytics and digital twins which can be considered as the major contributors to automated and digital manufacturing environments. Sustainability can be considered as the core of business strategy which is highlighted in the United Nations (UN) Sustainability 2030 agenda and includes smart manufacturing, energy efficient buildings and low-impact industrialization. Industry 4.0 technologies help to achieve sustainability in business practices. However, very limited studies reported about the extensive reviews on these two research areas. This study uses a systematic literature review approach to find out the current research progress and future research potential of Industry 4.0 technologies to achieve manufacturing sustainability. The role and impact of different Industry 4.0 technologies for manufacturing sustainability is discussed in detail. The findings of this study provide new research scopes and future research directions in different research areas of Industry 4.0 which will be valuable for industry and academia in order to achieve manufacturing sustainability with Industry 4.0 technologies.

scholarly journals Humor in Workplace Leadership: A Systematic Search Scoping Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Caroline Rosenberg ◽  
Arlene Walker ◽  
Michael Leiter ◽  
Joe Graffam
Keyword(s):  
Scoping Review ◽  
Cultural Context ◽  
Research Progress ◽  
Future Research ◽  
Theoretical Frameworks ◽  
Research Areas ◽  
Humor Studies ◽  
Significant Research ◽  
Future Research Directions ◽  
Leadership Research

Humor studies are increasingly prevalent in workplace and leadership domains, it has shown significant development in the last 40 years. The multifaceted nature of humor means varied definitions and diverse measurement approaches have been approved. As a result, research methodologies and findings are not easily clarified, and have not been synthesized. The aim of this scoping review was to review the existing body of literature relevant to humor in workplace leadership to identify key research areas, methodologies used, guiding theoretical frameworks, and gaps that are persisting over the last 40 years. Using qualitative review methods, four key themes in the research emerged relating to: (1) humor styles and outcomes; (2) humor as communication and discursive resource; (3) variables in the humor and leadership relationship; and (4) cultural context. This review demonstrates significant research progress on the topic of humor in workplace leadership. Research progress and gaps are discussed based on five key questions. Future research directions are outlined and discussed.

Metabolism and Distribution of Novel Tumor Targeting Drugs In Vivo

2020 ◽  
Vol 21 (13) ◽  
pp. 996-1008
Author(s):  
Mengli Wang ◽  
Qiuzheng Du ◽  
Lihua Zuo ◽  
Peng Xue ◽  
Chao Lan ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Small Molecule ◽  
High Efficiency ◽  
Tumor Therapy ◽  
Research Progress ◽  
Future Research ◽  
Pharmacokinetic Parameters ◽  
Molecular Characteristics ◽  
Targeted Drugs

Background: As a new tumor therapy, targeted therapy is becoming a hot topic due to its high efficiency and low toxicity. Drug effects of targeted tumor drugs are closely related to pharmacokinetics, so it is important to understand their distribution and metabolism in vivo. Methods: A systematic review of the literature on the metabolism and distribution of targeted drugs over the past 20 years was conducted, and the pharmacokinetic parameters of approved targeted drugs were summarized in combination with the FDA's drug instructions. Targeting drugs are divided into two categories: small molecule inhibitors and monoclonal antibodies. Novel targeting drugs and their mechanisms of action, which have been developed in recent years, are summarized. The distribution and metabolic processes of each drug in the human body are reviewed. Results: In this review, we found that the distribution and metabolism of small molecule kinase inhibitors (TKI) and monoclonal antibodies (mAb) showed different characteristics based on the differences of action mechanism and molecular characteristics. TKI absorbed rapidly (Tmax ≈ 1-4 h) and distributed in large amounts (Vd > 100 L). It was mainly oxidized and reduced by cytochrome P450 CYP3A4. However, due to the large molecular diameter, mAb was distributed to tissues slowly, and the volume of distribution was usually very low (Vd < 10 L). It was mainly hydrolyzed and metabolized into peptides and amino acids by protease hydrolysis. In addition, some of the latest drugs are still in clinical trials, and the in vivo process still needs further study. Conclusion: According to the summary of the research progress of the existing targeting drugs, it is found that they have high specificity, but there are still deficiencies in drug resistance and safety. Therefore, the development of safer and more effective targeted drugs is the future research direction. Meanwhile, this study also provides a theoretical basis for clinical accurate drug delivery.

Mix Networks: Existing Scenarios and Future Directions on Security and Privacy

2019 ◽  
Vol 14 ◽  
Author(s):  
Khaleel Ahmad ◽  
Afsar Kamal
Keyword(s):  
Security And Privacy ◽  
Research Progress ◽  
Future Research ◽  
Future Directions ◽  
Practical Solution ◽  
Research Gap ◽  
The Web ◽  
Privacy Enhancing Techniques

Background: Privacy enhancing techniques are developed in order to provide strong protection to cyberspace. These techniques aim to allow users to keep their identities hidden during the communication when they are sending email, making payments online, browsing the Web or posting to newsgroups. MixNet is the most practical solution for concealing identities of message and sender’s identities. Objective: It provides sender and receiver anonymity as well as message security. The main goal of MixNet is to overcome vulnerability and enhance the performance of communication. It can efficiently handle the messages of various length and produce desirable results with privacy. The main objective of this paper is to acquire information and concepts regarding MixNet. We also provide guidelines for future research and references. Methods : The designing of MixNet depends on what cryptosystem method is used. Symmetric and Asymmetric both are used. Other methods could be also used such as PIR, CSP and FDR model, RPC, Token-based approach or others. Result: In this paper we provide an overview of MixNet approaches and presented a survey on MixNet based techniques and different models. We also constructed the comparison tables as per our requirements for better understanding. For this purpose, we found a total of 120 articles related to the MixNet published between 1990 and 2018 from the most relevant scientific resources. However, only 86 papers were analyzed due to comprehensiveness and relevancy to this article. Conclusion: Focused on the security and privacy of communication and how it can be achieved. This survey also reveals research progress and research gap on MixNet.

A Review of Minimum Quantity Lubrication (MQL) based on Bibliometry

2020 ◽  
Vol 13 ◽  
Author(s):  
Gaurav Gaurav ◽  
Abhay Sharma ◽  
G S Dangayach ◽  
M L Meena
Keyword(s):  
Descriptive Analysis ◽  
Minimum Quantity Lubrication ◽  
Citation Network ◽  
Machining Process ◽  
Cutting Fluid ◽  
Future Research ◽  
Research Directions ◽  
Minimum Quantity ◽  
Research Areas ◽  
Future Research Directions

Background: Minimum quantity lubrication (MQL) is one of the most promising machining techniques that can yield a reduction in consumption of cutting fluid more than 90 % while ensuring the surface quality and tool life. The significance of the MQL in machining makes it imperative to consolidate and analyse the current direction and status of research in MQL. Objective: This study aims to assess global research publication trends and hot topics in the field of MQL among machining process. The bibliometric and descriptive analysis are the tools that the investigation aims to use for the data analysis of related literature collected from Scopus databases. Methods: Various performance parameters are extracted, such as document types and languages of publication, annual scientific production, total documents, total citations, and citations per article. The top 20 of the most relevant and productive sources, authors, affiliations, countries, word cloud, and word dynamics are assessed. The graphical visualisation of the bibliometric data is presented in terms of bibliographic coupling, citation, and co-citation network. Results: The investigation reveals that the International Journal of Machine Tools and Manufacture (2611 citations, 31 hindex) is the most productive journal that publishes on MQL. The most productive institution is the University of Michigan (32 publications), the most cited country is Germany (1879 citations), and the most productive country in MQL is China (124 publications). The study shows that ‘Cryogenic Machining’, ‘Sustainable Machining’, ‘Sustainability’, ‘Nanofluid’ and ‘Titanium alloy’ are the most recent keywords and indications of the hot topics and future research directions in the MQL field. Conclusion: The analysis finds that MQL is progressing in publications and the emerging with issues that are strongly associated with the research. This study is expected to help the researchers to find the most current research areas through the author’s keywords and future research directions in MQL and thereby expand their research interests.

Conclusion

2020 ◽  
pp. 698-719
Author(s):  
Ronald E. Rice ◽  
Simeon J. Yates ◽  
Jordana Blejmar
Keyword(s):  
Digital Technology ◽  
Digital Literacy ◽  
Theory Development ◽  
Policy Implications ◽  
Digital Culture ◽  
Future Research ◽  
Technology And Society ◽  
Ongoing Research ◽  
Positive Effects ◽  
Research Areas

We conclude the Handbook of Digital Technology and Society by identifying topics that appear in multiple chapters, are more unique to some chapters, and that represent general themes across the material. Each of these is considered separately for the ESRC theme chapters and the non-ESRC chapters. In the ESRC theme chapters, cross-cutting research topics include digital divides and inequalities; data and digital literacy; governance, regulation, and legislation; and the roles and impacts of major platforms. Cross-cutting challenges include methods; theory development, testing, and evaluation; ethics; big data; and multi-platform/holistic studies. Gaps include policy implications, and digital culture. In the non-ESRC chapters, more cross-cutting themes include future research and methods; technology venues; relationships; content and creation; culture and everyday life; theory; and societal effects. More unique, these were digitization of self; managing digital experience; names for the digital/social era; ethics; user groups; civic issues; health, and positive effects. The chapter also shows how the non-ESRC chapters may be clustered together based on their shared themes and subthemes, identifying two general themes of more micro and more macro topics. The identification of both more and less common topics and themes can provide the basis for understanding the landscape of prior research, what areas need to be included in ongoing research, and what research areas might benefit from more attention. The chapter ends with some recommendations for such ongoing and future research in the rich, important, and challenging area of digital technology and society.

scholarly journals Cybersickness in current-generation virtual reality head-mounted displays: systematic review and outlook

2021 ◽  
Author(s):  
Polona Caserman ◽  
Augusto Garcia-Agundez ◽  
Alvar Gámez Zerban ◽  
Stefan Göbel
Keyword(s):  
Systematic Review ◽  
Virtual Reality ◽  
Meta Analysis ◽  
Subjective Evaluation ◽  
Future Research ◽  
Current Generation ◽  
Research Areas ◽  
Head Mounted Displays ◽  
Skin Response ◽  
Golden Standard

AbstractCybersickness (CS) is a term used to refer to symptoms, such as nausea, headache, and dizziness that users experience during or after virtual reality immersion. Initially discovered in flight simulators, commercial virtual reality (VR) head-mounted displays (HMD) of the current generation also seem to cause CS, albeit in a different manner and severity. The goal of this work is to summarize recent literature on CS with modern HMDs, to determine the specificities and profile of immersive VR-caused CS, and to provide an outlook for future research areas. A systematic review was performed on the databases IEEE Xplore, PubMed, ACM, and Scopus from 2013 to 2019 and 49 publications were selected. A summarized text states how different VR HMDs impact CS, how the nature of movement in VR HMDs contributes to CS, and how we can use biosensors to detect CS. The results of the meta-analysis show that although current-generation VR HMDs cause significantly less CS ($$p<0.001$$ p < 0.001 ), some symptoms remain as intense. Further results show that the nature of movement and, in particular, sensory mismatch as well as perceived motion have been the leading cause of CS. We suggest an outlook on future research, including the use of galvanic skin response to evaluate CS in combination with the golden standard (Simulator Sickness Questionnaire, SSQ) as well as an update on the subjective evaluation scores of the SSQ.

scholarly journals Research on the Operating Characteristics of Hydraulic Free-Piston Engines: A Systematic Review and Meta-Analysis

Energies ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3530
Author(s):  
Fukang Ma ◽  
Shuanlu Zhang ◽  
Zhenfeng Zhao ◽  
Yifang Wang
Keyword(s):  
Systematic Review ◽  
High Efficiency ◽  
Meta Analysis ◽  
Combustion Process ◽  
Research Progress ◽  
Future Research ◽  
Operating Characteristics ◽  
Piston Engine ◽  
Free Piston ◽  
Free Piston Engine

The hydraulic free-piston engine (HFPE) is a kind of hybrid-powered machine which combines the reciprocating piston-type internal combustion engine and the plunger pump as a whole. In recent years, the HFPE has been investigated by a number of research groups worldwide due to its potential advantages of high efficiency, energy savings, reduced emissions and multi-fuel operation. Therefore, our study aimed to assess the operating characteristics, core questions and research progress of HFPEs via a systematic review and meta-analysis. We included operational control, starting characteristics, misfire characteristics, in-cylinder working processes and operating stability. We conducted the literature search using electronic databases. The research on HFPEs has mainly concentrated on four kinds of free-piston engine, according to piston arrangement form: single piston, dual pistons, opposed pistons and four-cylinder complex configuration. HFPE research in China is mainly conducted in Zhejiang University, Tianjin University, Jilin University and the Beijing Institute of Technology. In addition, in China, research has mainly focused on the in-cylinder combustion process while a piston is free by considering in-cylinder combustion machinery and piston dynamics. Regarding future research, it is very important that we solve the instabilities brought about by chance fluctuations in the combustion process, which will involve the hydraulic system’s efficiency, the cyclical variation, the method of predicting instability and the recovery after instability.

scholarly journals Rational design of photocatalysts for ammonia production from water and nitrogen gas

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Seokwoo Choe ◽  
Sung Min Kim ◽  
Yeji Lee ◽  
Jin Seok ◽  
Jiyong Jung ◽  
...  
Keyword(s):  
Energy Source ◽  
Rational Design ◽  
Future Research ◽  
Ammonia Production ◽  
Significant Progress ◽  
Nitrogen Gas ◽  
Research Directions ◽  
Effective Strategies ◽  
Future Research Directions ◽  
Made In

AbstractPhotocatalytic N2 reduction has emerged as one of the most attractive routes to produce NH3 as a useful commodity for chemicals used in industries and as a carbon-free energy source. Recently, significant progress has been made in understanding, exploring, and designing efficient photocatalyst. In this review, we outline the important mechanistic and experimental procedures for photocatalytic NH3 production. In addition, we review effective strategies on development of photocatalysts. Finally, our analyses on the characteristics and modifications of photocatalysts have been summarized, based on which we discuss the possible future research directions, particularly on preparing more efficient catalysts. Overall, this review provides insights on improving photocatalytic NH3 production and designing solar-driven chemical conversions.

Sign in / Sign up

Export Citation Format

Share Document