scholarly journals Biosynthesis of Metal Nanoparticles: A Review

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Narendra Kulkarni ◽  
Uday Muddapur

The synthesis of nanostructured materials, especially metallic nanoparticles, has accrued utmost interest over the past decade owing to their unique properties that make them applicable in different fields of science and technology. The limitation to the use of these nanoparticles is the paucity of an effective method of synthesis that will produce homogeneous size and shape nanoparticles as well as particles with limited or no toxicity to the human health and the environment. The biological method of nanoparticle synthesis is a relatively simple, cheap, and environmentally friendly method than the conventional chemical method of synthesis and thus gains an upper hand. The biomineralization of nanoparticles in protein cages is one of such biological approaches used in the generation of nanoparticles. This method of synthesis apart from being a safer method in the production of nanoparticles is also able to control particle morphology.

2013 ◽  
Vol 667 ◽  
pp. 251-254 ◽  
Author(s):  
Ropisah Mie ◽  
Mohd Wahid Samsudin ◽  
Laily B. Din

The development of reliable and eco-friendly metallic nanoparticles needs some consideration on the chemical procedures involved in the synthesis of nanomaterials. The conventional methods in the production of metallic nanoparticles generate a large amount of hazardous byproducts. Thus, there is a need for ‘green chemistry’ that includes a clean, nontoxic and environment-friendly method of nanoparticle synthesis [1]. As an alternative, biological methods are considered safe and ecologically sound for the nanomaterial fabrication [2]. Therefore, in this review special attention is focused on the biosynthesis of nanoparticles from natural resources as compared as ordinary chemical method. Biosynthesis of nanoparticles using plant is a new development of green nanotechnology beneficial to environmental and to the plant itself. It also plays a significant role in the field of biology and medicine.


2021 ◽  
Vol 19 (3) ◽  
pp. 247-257
Author(s):  
Yuliya A. Morozova ◽  
Dmitry S. Dergachev ◽  
Mikhail A. Subotyalov

Over the past few decades, nanoparticles of metals, and in particular silver, with a diameter of less than 100 nm have significantly expanded their field of application for various biomedical purposes. So, silver nanoparticles have great potential in a wide range of applications as antimicrobial agents, coatings for biomedical products, carriers for drug delivery, bioengineering, since they have discrete physical properties and wide biochemical functionality. Studies have shown that the size, morphology, stability and properties (chemical and physical) of metal nanoparticles are strongly influenced by the conditions of the experiment, the kinetics of the interaction of metal ions with reducing agents and the adsorption processes of the stabilizer with metal nanoparticles. This review aims to analyze the use of silver nanoparticles in modern medicine based on data from domestic and foreign literature over the past five years. The study confirmed the high biological activity of drugs with nanoserebrum as anti-inflammatory, antimicrobial agents, antifungals, the presence of an inhibitory effect on protozoa, antioxidant and anticancer effects, and substantiated the relevance of use in bioengineering and dentistry. However, rapid advances and advances in technology have led to concerns about the potential risk associated with the use and application of silver nanoparticles to human health and the environment. Therefore, this review attempts to characterize and quantify the potential harmful effects of silver nanoparticles on the health of laboratory animals and humans, and focuses on ways to neutralize or reduce the toxic effects of silver nanoparticles on the human body.


Author(s):  
Azizjon A. Khakimov ◽  
◽  
Jurabek Nodirjonovich Yakhyoyev ◽  

In recent years, great importance has been attached to the biological protection of plants. Because, no matter how effective the chemical method, it has its own disadvantages. A number of means of this method, in particular, many chemicals are harmful and dangerous to human health, warm-blooded animals and the environment, as well as to all beneficial insects, that is - biological agents. Therefore, in addition to the cultivation of resistant varieties, it is advisable to use the biological method in areas where insects and canals fall.


Author(s):  
Anikate Sood ◽  
Shweta Agarwal

Nanotechnology is the most sought field in biomedical research. Metallic nanoparticles have wide applications in the medical field and have gained the attention of various researchers for advanced research for their application in pharmaceutical field. A variety of metallic nanoparticles like gold, silver, platinum, palladium, copper and zinc have been developed so far. There are different methods to synthesize metallic nanoparticles like chemical, physical, and green synthesis methods. Chemical and physical approaches suffer from certain drawbacks whereas green synthesis is emerging as a nontoxic and eco-friendly approach in production of metallic nanoparticles. Green synthesis is further divided into different approaches like synthesis via bacteria, fungi, algae, and plants. These approaches have their own advantages and disadvantages. In this article, we have described various metallic nanoparticles, different modes of green synthesis and brief description about different metabolites present in plant that act as reducing agents in green synthesis of metallic nanoparticles. 


2021 ◽  
pp. 002203452110018
Author(s):  
J.T. Wright ◽  
M.C. Herzberg

Our ability to unravel the mysteries of human health and disease have changed dramatically over the past 2 decades. Decoding health and disease has been facilitated by the recent availability of high-throughput genomics and multi-omics analyses and the companion tools of advanced informatics and computational science. Understanding of the human genome and its influence on phenotype continues to advance through genotyping large populations and using “light phenotyping” approaches in combination with smaller subsets of the population being evaluated using “deep phenotyping” approaches. Using our capability to integrate and jointly analyze genomic data with other multi-omic data, the knowledge of genotype-phenotype relationships and associated genetic pathways and functions is being advanced. Understanding genotype-phenotype relationships that discriminate human health from disease is speculated to facilitate predictive, precision health care and change modes of health care delivery. The American Association for Dental Research Fall Focused Symposium assembled experts to discuss how studies of genotype-phenotype relationships are illuminating the pathophysiology of craniofacial diseases and developmental biology. Although the breadth of the topic did not allow all areas of dental, oral, and craniofacial research to be addressed (e.g., cancer), the importance and power of integrating genomic, phenomic, and other -omic data are illustrated using a variety of examples. The 8 Fall Focused talks presented different methodological approaches for ascertaining study populations and evaluating population variance and phenotyping approaches. These advances are reviewed in this summary.


Author(s):  
PA Ganichev

Introduction: Polymer products have become inexpensive, convenient and widely used in all spheres of everyday life recently. Microplastics are found in seawater, wastewater, fresh water, foodstuffs, and air. Over the past few years, the presence of microplastics in treated tap and bottled water has been reported, raising questions and concerns about their potential human health effects. Objective: To summarize and systematize the results of studying health effects of exposure to microplastics in potable water. Materials and methods: A literature review was done based on ten topical articles and reviews published in 2014–2021 out of 64 sources found in the PubMed and Scopus international databases and the Russian Science Citation Index (RSCI). Results and conclusions: Generalization and systematization of the published research data demonstrated the lack of strong evidence to draw conclusions about human health effects of microplastics. Information on toxicokinetics and toxicodynamics of ingested microplastic particles is absent just like the studies of the most common shapes and sizes of plastic particles and health risks from exposure to such particles in drinking water.


Author(s):  
Rashid Bhatti ◽  
Hadia Shakeel ◽  
Kousar Malik ◽  
Muhammad Qasim ◽  
Mohsin Ahmad Khan ◽  
...  

During the last few decades, nanotechnology has gained many applications in almost all fields of life because of the unique properties of nanoparticles. Nanotechnology has specially marked its name in the field of medicine. However, nanoparticles toxicity is detrimental to human health and is a prime concern in applied medicine. They can cause insomnia, vertigo, madarosis, epistaxis, hypokalemia, lymphopenia, Alzheimer's and Parkinson's diseases, etc. There is a gap in knowledge regarding the study of the toxicological effects of nanoparticles. Mechanisms that are responsible for this toxicity are not fully understood yet. Phytochemicals have natural therapeutic effects of reducing metal nanoparticles' toxicity by acting as stabilizers and nontoxic reducing agents. However, the interaction between phytochemicals and nanoparticles is remained to be elucidated. This review will provide in-depth knowledge about the various types of inorganic nanoparticles and their associated toxicities, key parameters determining the toxic behaviour of nanoparticles, and the mechanisms behind their cytotoxicity. It also emphasizes the need for further research to understand the interaction between various phytochemicals and nanoparticles for therapeutic purposes.


2021 ◽  
Vol 3 (1) ◽  
pp. 18
Author(s):  
Thi Tuong Vy Phan

The chemical and physical routes are usually used to synthesize metal nanoparticles. However, the harmful effects on the environment and human health has turned scientists into finding greener methods. We have developed the novel green method for the synthesis of flower Pd nanoparticles based on the chitosan (CS) polymer. In this method, CS can work as a stabilizer, a shape-directing agent, and a size-controllable agent for the synthesis of these nanoparticles. This study provides pioneer evidence about the multifunctional roles of natural polymers in the preparation of metal nanoparticles. Deep and extensive studies should be conducted to explore the great benefits of natural polymers in the green synthesis of metal nanoparticles.


2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Sebastian Franco-Ulloa ◽  
Giuseppina Tatulli ◽  
Sigbjørn Løland Bore ◽  
Mauro Moglianetti ◽  
Pier Paolo Pompa ◽  
...  

Abstract The fundamental interactions underlying citrate-mediated chemical stability of metal nanoparticles, and their surface characteristics dictating particle dispersion/aggregation in aqueous solutions, are largely unclear. Here, we developed a theoretical model to estimate the stoichiometry of small, charged ligands (like citrate) chemisorbed onto spherical metallic nanoparticles and coupled it with atomistic molecular dynamics simulations to define the uncovered solvent-accessible surface area of the nanoparticle. Then, we integrated coarse-grained molecular dynamics simulations and two-body free energy calculations to define dispersion state phase diagrams for charged metal nanoparticles in a range of medium’s ionic strength, a known trigger for aggregation. Ultraviolet-visible spectroscopy experiments of citrate-capped nanocolloids validated our predictions and extended our results to nanoparticles up to 35 nm. Altogether, our results disclose a complex interplay between the particle size, its surface charge density, and the ionic strength of the medium, which ultimately clarifies how these variables impact colloidal stability.


2020 ◽  
Vol 996 ◽  
pp. 76-81
Author(s):  
Ben Jiao Li ◽  
Song Li ◽  
Bin Rong Ma ◽  
Yong Jing ◽  
Zhe Ming Zhang ◽  
...  

Silver inorganic antibacterial agents have been widely used inbiotechnology, bioengineering science, electronics, optics and water treatment because of their strong bactericidal ability, high safety and durable antibacterial properties. In this paper, the preparation methods of silver nanoparticles are reviewed, including physical method, chemical method and biological method, in order to provide a reference for the further development and utilization of silver nano-antibacterial materials.


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