scholarly journals Own Experience in Treatment of Patients with Penile Cancer Using Photodynamic Therapy

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Elena Filonenko ◽  
Andrey Kaprin ◽  
Boris Alekseev ◽  
Antonina Urlova
Keyword(s):  
Quality Of Life ◽  
Photodynamic Therapy ◽  
Topical Application ◽  
Penile Cancer ◽  
Mental Condition ◽  
Photodynamic Diagnosis ◽  
Combined Modality Treatment ◽  
Complete Regression ◽  
Oncological Results

Penile cancer is a rare pathology. For penile cancer surgical treatment, radiotherapy, chemotherapy, and combined modality treatment are available. Because of great importance of this organ for mental condition of patient, the development of organ-preserving methods allowing to minimize impact on patient’s quality of life without compromising of oncological results is desirable. In the Center of Laser and Photodynamic diagnosis and treatment of tumors in P.A. Herzen Moscow Cancer Research Institute the methods of photodynamic therapy in patients with penile cancer have been developed. From 2011 to 2013 the treatment was conducted in 11 patients with precancer and cancer of penile. The average age was 56.6. According to morphological diagnosis photodynamic therapy (PDT) was performed using two methods. One method included topical application of agent for PDT and the second intravenous administration of photosensitizer. For topical application alasens was used and for intravenous injection we applied radachlorine. All patients had no complications. Complete regression was achieved in 9 patients, and partial regression in 2. Thus, the results showed that photodynamic therapy for penile cancer stage Tis-1N0M0 permits performing organ-preserving treatment with satisfactory oncological results and no impairment of patient’s quality of life.

Thulium–yttrium–aluminium–garnet (Tm:YAG) laser treatment of penile cancer: oncological results, functional outcomes, and quality of life

2017 ◽  
Vol 36 (2) ◽  
pp. 265-270 ◽  
Author(s):  
Gennaro Musi ◽  
Andrea Russo ◽  
Andrea Conti ◽  
Francesco A. Mistretta ◽  
Ettore Di Trapani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Laser Treatment ◽  
Functional Outcomes ◽  
Penile Cancer ◽  
Yttrium Aluminium Garnet ◽  
Yttrium Aluminium ◽  
Tm:Yag Laser ◽  
Oncological Results

scholarly journals Photodynamic therapy in patients with skin metastases of disseminated melanoma

2019 ◽  
Vol 8 (1) ◽  
pp. 24-28
Author(s):  
D. A. Tzerkovsky ◽  
N. A. Petrovskaya ◽  
A. N. Mazurenko
Keyword(s):  
Quality Of Life ◽  
Photodynamic Therapy ◽  
Semiconductor Laser ◽  
Power Density ◽  
Tumor Volume ◽  
Complete Regression ◽  
Skin Melanoma ◽  
Who Criteria

The aim of the study was to evaluate the immediate results of photodynamic therapy (PDT) in patients with intradermal metastases of skin melanoma. The study included 50 patients who received treatment at the department of hyperthermia and photodynamic therapy. The study included 23 (46%) men and 27 (54%) women with an average age of 60.7±10.4 years. PDT of tumors was carried out 3–4 hours after intravenous administration of a chlorine-based photosensitizer (Photolon) in doses of 1.5–3 mg/kg using a semiconductor laser «UPL-PDT» (Lemt, Belarus, λ=660±5 nm). The exposure doses varied from 100 to 400 J/cm2; power density – from 0.2 to 0.9 W/cm2; power – from 0.25 to 1 W and time of PDT of one focus was dependent on the size and location of the tumor and was 5 to 20 minutes. Evaluation of antitumor efficacy of PDT was carried out according to WHO criteria. The terms of follow-up of patients were between 3 and 23 months. At follow-up observation, 1–3 months after the treatment, complete regression of intradermal metastases of skin melanoma was achieved in 9 (18%) patients, partial – in 28 (56%), process stabilization in 8 (16%) and progression in 5 (10%)) patients. The objective effect was achieved in 74% of patients, the therapeutic – in 90%. PDT can be used in the treatment of intradermal metastases of disseminated skin melanoma with palliative purposes and allows reducing the tumor volume, which significantly improves the quality of life of patients.

scholarly journals Comparison of Quality of Life between Active and Inactive Workers

2020 ◽  
Author(s):  
Mohammad Hassan Dashty Khavidaki ◽  
Mahmood Kamali Zarch ◽  
Naser Mohammadi Ahmadabadi ◽  
Haider Hosseini
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Mental Condition ◽  
Positive Role ◽  
Cross Sectional ◽  
Positive Effects ◽  
Sf 36 ◽  
Significant Difference ◽  
Cement Manufacturing

Introduction: Numerous important factors such as physical and mental condition affect the quality of life Job stress is one of the key factors in decreasing productivity in organizations. Given the positive effects of physical activity on quality of life, this study aimed to compare the quality of life between active and inactive workers (case study). Methods: This study was a cross-sectional comparative study.190 tile and cement-manufacturing workers who were eligible for the study were selected completely voluntarily, based on a convenience sampling. Of these, according to Beck questionnaire, 88 were selected in inactive and 64 in active groups; Weir and Sherborn questionnaire was used for assessing the quality of life (SF-36). For analysis the data, independent T-test and SPSS 23 software were used for analysis (P≤0.05). Results: The results showed that physical, psychological and quality of life components in the active group of cement factory workers were (p = 0.012) (p = 0.001) (p = 0.005) and tile workers (p = 0.012) (P = 0.005) (p = 0.014) was a significant and more compare to the inactive group, but there was no significant difference between active and inactive workers of the two tile and cement factories. Conclusion: The results of this study showed the positive role of exercise and physical activity on the quality of life of people working in cement and tile factories. It seems easier physical activity and sports are related to the quality of life of workers and have nothing to do with the workplace.  

scholarly journals Decision Regret and Quality of Life after Focal Therapy with Vascular-Targeted Photodynamic Therapy (TOOKAD®) for Localized Prostate Cancer

2021 ◽  
pp. 1-6
Author(s):  
Luka Flegar ◽  
Martin Baunacke ◽  
Bjoern Thorben Buerk ◽  
Rick Proschmann ◽  
Aristeidis Zacharis ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Decision Making ◽  
Photodynamic Therapy ◽  
Local Recurrence ◽  
Post Treatment ◽  
Decision Regret ◽  
Targeted Photodynamic Therapy ◽  
Decisional Regret

<b><i>Purpose:</i></b> The aim of the study was to assess quality of life (QoL), decision involvement, and decisional regret after treatment with vascular-targeted photodynamic therapy (VTP) (TOOKAD®) for unilateral low-risk prostate cancer. <b><i>Methods:</i></b> Validated questionnaires (EORTC QLQ-C30 and QLQ-PR25) capturing QoL post-treatment, involvement in decision-making (Control Preferences Scale) and decision regret (Decisional Regret Scale), were given to patients at the 12-month visit after undergoing VTP at our institution between May 2018 and February 2021. <b><i>Results:</i></b> Out of 44 patients, 36 patients were included in this study and 31 (86.1%) responded to the questionnaires. Mean overall health score capturing QoL at 12 months was 79.3 (standard deviation: ±18.1). 70.9% of the patients (<i>n</i> = 22) had no decision regret, and 67.8% of men (<i>n</i> = 21) had an active role in decision-making. In control biopsy at 12 months post-treatment, 19.4% of patients (<i>n</i> = 7) presented with local recurrence and progression to higher Gleason score (GS) was found in 13.8% of patients (<i>n</i> = 5). Patients (<i>n</i> = 3) presenting with tumor recurrence or progression to higher GS in control biopsy showed a significantly higher level of decision regret (<i>p</i> &#x3c; 0.009). <b><i>Conclusion:</i></b> Only 9.7% of men (<i>n</i> = 3) felt a strong emotion of regret at 12 months after VTP. Level of decision regret was significantly higher in patients with local recurrence or tumor progression detected in control biopsy. QoL was stable after VTP.

scholarly journals EVALUATION OF THE QUALITY OF LIFE IN PATIENTS WITH LUNG CARCINOMA AFTER PNEUMONECTOMY

2021 ◽  
Vol 20 (3) ◽  
pp. 90-97
Author(s):  
E. A. Toneev ◽  
O. V. Pikin ◽  
V. I. Orelkin ◽  
A. L. Charyshkin ◽  
A. A. Martynov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Functional Status ◽  
Short Form ◽  
Special Treatment ◽  
Combined Modality Treatment ◽  
Concomitant Disease ◽  
Extent Of Surgery ◽  
Questionnaire Method

Background. Pneumonectomy is one of the most traumatic thoracic surgeries, leading to a significant decrease in the patient’s functional status. Despite numerous questionnaires, there is no standard approach to the study of the quality of life of patients who have undergone radical surgery for lung cancer.The purpose of the study was to conduct a retrospective analysis of the quality of life of patients who underwent pneumonectomy during the period 2017–2018, taking into account the extent of surgery, presence of concomitant disease and adjuvant antitumor treatment.Material and Methods. Changes in the quality of life (qol) during combined modality treatment were evaluated in 40 patients with non-small cell lung cancer. To assess the functional status, the criteria adopted for determining the surgical risk were used. The st. George`s Respiratory Questionnaire (sgrq) and Quality Outcomes study short-Form 36 (sf-36) were used to assess the respiratory system of patients. Data collection was carried out 12 months after surgery using a questionnaire method based on a direct survey of respondents.Conclusion. Postoperative special treatment significantly worsens both the functional parameters of patients and the quality of life. Thus, a multidisciplinary approach to the management of patient with participation of an oncologist, pulmonologist, physiotherapist, and rehabilitologist is required.

scholarly journals Quality of life of blind people’s carers

2020 ◽  
Vol 66 (3) ◽  
Author(s):  
Łukasz Lewandowski ◽  
Iwona Smotryś ◽  
Angelika Puls ◽  
Anita Radziejewska ◽  
Magda Płocharczyk ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Married Couples ◽  
Educational Background ◽  
Mental Condition ◽  
Professional Activity ◽  
Self Assessment ◽  
The Disabled ◽  
Sight Loss

Introduction: Quality of life is a multidimensional concept and a subjective value that depends on many factors. Disability caused by sight loss induces changes for both patients and their carers. The function of a blind person’s carer is usually performed by family members, whose limited knowledge limits their ability to help effectively and satisfactorily. This, in turn, may lead to their reduced sense of the quality of life.The aim of this study was to assess the quality of life of blind people’s carers.Materials and methods: The study was conducted September–October 2016 and involved 130 blind peoples’ carers using a diagnostic poll. Short Form Survey SF-36 and a specially designed questionnaire were used. The majority of participants were women (69.23%), married couples (63.1%), with high school education (40.77%).Results: Wellbeing self-assessment indicated that 36.15% of carers considered their mental condition to have worsened, while 43.08% remained at the same level when compared to 1 year earlier. Analysis of quality of life showed that carers very highly rated their physical functioning 59.46 ±26.35; social functioning 57.4 ±26.12; vitality 55.48 ±23.27; and emotional functioning 54.81 ±29.24.Conclusions: Quality of life tends to gradually deteriorate as the carers grow older. The carer’s educational background and the professional activity of the disabled person influence the assessment of the carer’s quality of life.

scholarly journals Suicidal ideation among medical students, burnout or depression? Maybe both.

2021 ◽  
Vol 11 (1) ◽  
pp. 69-77
Author(s):  
THAÍS CAMPELO BEDÊ VALE ◽  
LÍVIA RODRIGUES DE ARAÚJO ◽  
VITÓRIA NUNES MEDEIROS ◽  
JOSÉ HÍCARO HELLANO GONÇALVES LIMA PAIVA ◽  
TATIANA PASCHOALETTE RODRIGUES BACHUR ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Medical Students ◽  
Suicidal Ideation ◽  
Emotional Support ◽  
Female Gender ◽  
Sleep Time ◽  
Mental Condition ◽  
Cross Sectional

Depression is a common mental condition worldwide and a major cause of debility, with the potential to impair the quality of life of affected people. Medical students are more likely to develop psychiatric disorders, with depression, anxiety, and burnout being the most common ones. The aim of this study was to investigate the prevalence of depressive symptoms in medical students and their association with burnout and aspects of life. This is an analytical cross-sectional study. Data collection was performed using four validated scales and a questionnaire in 511 medical students from the first to the fourth year from different universities. Depression was present in 49% of the students. A correlation was found between depression and female gender. Regarding the students' daily sleep time, 54.5% of the students slept only 3 to 6 hours per night. The use of psychoactive substances was reported by 29.9%. Regarding the emotional support offered by universities, about 92.8% of students with depressive symptoms reported not receiving adequate emotional support. As for quality of life, all domains were impaired among students with depression. According to the two-dimensional criterion, 37% of the students have burnout, with correlation between the presence of the syndrome and depressive symptoms. In addition, burnout proved to be an independent risk factor for suicidal ideation and self-mutilation. New methods that can help detect and address factors that trigger stress and depressive symptoms in medical students are needed to reduce the incidence of depression.

Gambaran Kualitas Hidup Pekerja Pra Lanjut Usia (45-56 Tahun) Dengan Sindrom Metabolik Di PT. X Tahun 2020

2021 ◽  
Vol 2 (3) ◽  
pp. 114-127
Author(s):  
Fierdania Yusvita ◽  
Putri Handayani ◽  
Nadya Shinta Nandra
Keyword(s):  
Quality Of Life ◽  
Metabolic Syndrome ◽  
Health Condition ◽  
Mental Condition ◽  
Degenerative Diseases ◽  
Interview Method ◽  
Qualitative Descriptive ◽  
Obesity Hypertension ◽  
Descriptive Method

Quality of life can be determined by the individual's perception of his current life, including his health condition. Among occupational diseases, degenerative diseases are the first cause of death, and metabolic syndrome is one of them. This study aims to describe the quality of life of pre-elderly workers (45-56 years) with the risk of metabolic syndrome (obesity, hypertension, hypercholesterolemia and hyperglycemia) at PT. X. The research was conducted with a qualitative descriptive method. Data was collected by interview method and the results of medical check-up documents. The results showed that the respondents rated their quality of life quite well. They judged that his current physical condition was quite good. Respondents do not know that their current health condition can trigger degenerative diseases in the future if sedentary behavior is still ignored. Five of the seven respondents still do not exercise regularly and three of the seven respondents are active smokers with cigarette consumption of 3-20 cigarettes/day. The seven respondents did not pay enough attention to their food intake. Psychologically, respondents perceive their mental condition is very good, they perceive the work environment as a very comfortable place to build social relationships. More metabolic syndrome related support programs at PT X need to be offered to increase workers' awareness of their health status.

scholarly journals Long-term results of ERCP- or PTCS-directed photodynamic therapy for unresectable hilar cholangiocarcinoma

2020 ◽  
Author(s):  
Zongyan Li ◽  
Xiaofeng Jiang ◽  
Hua Xiao ◽  
Shaoyi Chen ◽  
Wenfeng Zhu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Photodynamic Therapy ◽  
Adverse Events ◽  
Survival Time ◽  
Surgical Resection ◽  
Stent Placement ◽  
Median Survival Time ◽  
Hilar Cholangiocarcinoma ◽  
Stent Group

Abstract Background Photodynamic therapy (PDT) can be performed as palliative therapy for cholangiocarcinoma, while there is currently insufficient evidence for the efficacy. The aim of this study was to explore the clinical efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP)- or percutaneous transhepatic cholangioscopy (PTCS)-directed PDT combined with stent placement for unresectable hilar cholangiocarcinoma. Methods A retrospective analysis was conducted on 62 patients with unresectable hilar cholangiocarcinoma. Thirty patients received PDT using hematoporphyrin combined with biliary stent placement (PDT+stent group), including 22 receiving ERCP-directed PDT and 8 receiving PTCS-directed PDT. Survival time, quality of life, and postoperative adverse events were compared to 32 patients receiving biliary stent placement alone (Stent-only group). Results After 42 months of follow-up, median survival time was significantly longer in the PDT+stent group than the Stent-only group (14.2 vs. 9.8 months, P = 0.003). In the PDT+stent group, the median survival time was longer in the 6 patients with recurrence after surgical resection than the 24 patients without prior surgical resection (20.0 vs. 13.0 months, P = 0.017). The QOL total scores was significantly higher in the PDT+stent group than the Stent-only group at postoperative 6, 9, and 12 months (P<0.05). There was no significant difference in the incidence of postoperative adverse events between the two groups (24 [38.7%] vs. 20 [29.0%], P = 0.239). Conclusion ERCP- or PTCS-directed PDT + stent placement can prolong the survival of patients with unresectable hilar cholangiocarcinoma, especially those with recurrence and improve quality of life without increasing adverse events.

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