scholarly journals The Impact ofPlasmodiumInfection on Placental Histomorphology: A Stereological Preliminary Study

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
John Ahenkorah ◽  
Patience B. Tetteh-Quarcoo ◽  
Mercy A. Nuamah ◽  
Bethel Kwansa–Bentum ◽  
Hanson G. Nuamah ◽  
...  

Background. Malaria during pregnancy may threaten the mother’s health and cause serious structural damage to the internal architecture of the placenta, which subsequently affects the pregnancy outcome. A better understanding of the impact of malaria parasites on the placenta morphology is crucial for better management of pregnant women and their babies.Aim. To assess by stereology the histomorphology of selected placental structures in placenta malaria compared with normal placentae at term.Method. A total of 10 placentae comprising 5 controls and 5 cases were selected from 50 placentae that were collected at term (38 weeks ± 2 weeks) from the maternal delivery suit of Korle-Bu Teaching Hospital in Accra, Ghana. Blood from the placentae was collected for both rapid diagnostic test and microscopic examinations. Samples collected were examined forPlasmodiumparasites, after which they were classified as study group (Plasmodiumpositive) or control (Plasmodiumnegative). Stereological quantification using systematic uniform random sampling technique with test point and intersection counting of photomicrographs were employed to estimate the mean volume densities of syncytial knots, syncytial necrosis, foetal capillaries, and intervillous spaces of the placentae on a total of 1,600 photomicrographs.Results. Out of the fifty placental samples from the maternal side tested forPlasmodium,six representing 12% were found to be infected with the parasite by both rapid diagnostic test and microscopy. On stereological assessment, the mean volume density of syncytial knots was significantly higher in the placental malaria group compared with the control placentae at term (P = 0.0080), but foetal capillaries (P = 0.7813), intervillous spaces (P = 0.8078), and syncytial necrosis (P = 0.8249) were not significantly different.Conclusion. This preliminary result indicates that placental malaria may cause significant increase in the syncytial knots but not foetal capillaries, intervillous spaces, or syncytial necrosis. This finding signifies early maturation of the placenta and may be crucial in understanding perinatal outcomes.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Clare Shakespeare ◽  
Handsome Dube ◽  
Sikhangezile Moyo ◽  
Solwayo Ngwenya

Abstract Background On the 27th of March 2020 the Zimbabwean government declared the Covid-19 pandemic a ‘national disaster’. Travel restrictions and emergency regulations have had significant impacts on maternity services, including resource stock-outs, and closure of antenatal clinics during the lockdown period. Estimates of the indirect impact of Covid-19 on maternal and perinatal mortality was expected it to be considerable, but little data was yet available. This study aimed to examine the impact of Covid-19 and lockdown control measures on non-Covid outcomes in a government tertiary level maternity unit in Bulawayo, Zimbabwe, by comparing maternal and perinatal morbidity and mortality before, and after the lockdown was implemented. Methods This was a retrospective, observational study, using a cross-sectional design to compare routine monthly maternal and perinatal statistics three months before and after Covid-19 emergency measures were implemented at Mpilo Central Hospital. Results Between January-March and April-June 2020, the mean monthly deliveries reduced from 747.3 (SD ± 61.3) in the first quarter of 2020 to 681.0 (SD ± 17.6) during lockdown, but this was not statistically significant, p = 0.20. The Caesarean section rates fell from a mean of 29.8% (SD ± 1.7) versus 28.0% (SD ± 1.7), which was also not statistically significant, p = 0.18. During lockdown, the percentage of women delivering at Mpilo Central Hospital who were booked at the hospital fell from a mean of 41.6% (SD ± 1.1) to 35.8% (SD ± 4.3) which was statistically significant, p = 0.03. There was no significant change, however, in maternal mortality or severe maternal morbidity (such as post-partum haemorrhage (PPH), uterine rupture, and severe preeclampsia/eclampsia), stillbirth rate or special care baby unit admission. There was an increase in the mean total number of early neonatal deaths (ENND) (mean 18.7 (SD ± 2.9) versus 24.0 (SD ± 4.6), but this was not statistically significant, p = 0.32. Conclusions Overall, maternity services at Mpilo showed resilience during the lockdown period, with no significant change in maternal and perinatal adverse outcomes, with the same number of man-hours worked before and during the lockdown Maternal and perinatal outcomes should continue to be monitored to assess the impact of Covid-19 and the lockdown measures as the pandemic in Zimbabwe unfolds. Further studies would be beneficial to explore women’s experiences and understand how bookings and deliveries at local clinics changed during this time.


2018 ◽  
Vol 4 (2) ◽  
pp. 129
Author(s):  
Nadya Puspita Dewi ◽  
Tetti Solehati ◽  
Nur Oktavia Hidayati

Dysmenorrhea is a pain before or during the menstrual period. The impact of dysmenorrhea are the disruption on physical function, emotional, social and school activities and disruption of quality of life. The study purpose is to detect the quality of life of adolescents with dysmenorrhea.The research method was a quantitative descriptive with total sampling technique to 195 students which selected using dysmenorrhea screening. The data were collected using the pediatric quality of life 4.0 generic module (PedsQL) teens report in Indonesian version which the validity and reliability have been tested. Analysis of data has been done to find out the mean value in each dimension and frequency distribution. The results showed that the mean value of the quality of life of adolescents with dysmenorrhea in general was 62,04 ± 8,15 and 51,8% was in the low. The mean value in physical dimension was 49,36 ± 9,19, emotional dimension was 57,62 ± 13,16, social dimension was 86,38 ± 13,28, and in the school dimension was 62,41 ± 14,77. The quality of life in high categories were in the emotional dimension (60,0%), social dimension (64,1%), and school dimension (60,5%). Meanwhile, the quality of life in low category was in the physical dimension (57,4%). It showed that the quality of life of adolescents with dysmenorrhea in SMK Negeri 2 Sumedang were low. It was recommended to the school and the health office in Sumedang district to provide the reproductive health education, specifically about the prevention and the treatment of dysmenorrhea on adolescents.  


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jeong Yee ◽  
Woorim Kim ◽  
Ji Min Han ◽  
Ha Young Yoon ◽  
Nari Lee ◽  
...  

Abstract This systematic review and meta-analysis aimed to evaluate the impact of COVID-19 on pregnant women. We searched for qualified studies in PubMed, Embase, and Web of Science. The clinical characteristics of pregnant women with COVID-19 and their infants were reported as means and proportions with 95% confidence interval. Eleven studies involving with 9032 pregnant women with COVID-19 and 338 infants were included in the meta-analysis. Pregnant women with COVID-19 have relatively mild symptoms. However, abnormal proportions of laboratory parameters were similar or even increased, compared to general population. Around 30% of pregnant women with COVID-19 experienced preterm delivery, whereas the mean birth weight was 2855.9 g. Fetal death and detection of SARS-CoV-2 were observed in about 2%, whereas neonatal death was found to be 0.4%. In conclusion, the current review will serve as an ideal basis for future considerations in the treatment and management of COVID-19 in pregnant women.


2020 ◽  
Vol III (I) ◽  
pp. 21-26
Author(s):  
Faheemullah Khan ◽  
Abdurrehman

Professional attitude has a key role in performing any duty. If a person lacks positive professional attitude or has natural attitude towards his/her profession then it creates many problems. So there for positive professional attitude has fruitful results in performing any task. This study was initiated to know the impact of demographic difference, locality and gender upon professional attitude of physical education professionals. Total 125 participants participated in this study which was selected through purposive sampling technique. Consents of 77 male and 48 female were taken for the purpose of gender based difference impact and in which 50 were from rural and 75 were from urban setup. It was for locality wise difference. Data was collected through questionnaire and was analyzed by using SPSS. The concluded results shown that gender differences has no significant impact upon professional attitude of physical education professionals and similarly locality is also has no significant impact upon professional attitude of physical education professionals. Both groups were found same in locality basis and gender basis. The mean score of both groups were found significantly same.


Author(s):  
Ruth Aguilar ◽  
Sonia Machevo ◽  
Clara Menéndez ◽  
Azucena Bardají ◽  
Augusto Nhabomba ◽  
...  

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Jacqueline Deen ◽  
Mavuto Mukaka ◽  
Lorenz von Seidlein

Abstract Background Reactive malaria case detection involves the screening of those in contact with index cases and is used in countries in the Greater Mekong Sub-region. The yield of reactive case detection, defined here as the percentage of positive malaria cases among potential contacts who were screened, was assessed. Methods A literature search was conducted on PubMed to identify studies on reactive case detection in the Greater Mekong Sub-region. Eligible published articles were reviewed and pooled estimates from the studies were calculated, by type of malaria test used. Results Eighty-five publications were retrieved, of which 8 (9.4%) eligible articles were included in the analysis. The yield from reactive case detection ranged from 0.1 to 4.2%, with higher rates from PCR testing compared with microscopy and/or rapid diagnostic test. The overall yield from microscopy and/or rapid diagnostic test was 0.56% (95% CI 0.31–0.88%), while that from PCR was 2.35% (95% CI 1.19–3.87%). The two studies comparing different target groups showed higher yield from co-workers/co-travellers, compared with household contacts. Conclusion In low malaria transmission settings, the effectiveness of reactive case detection is diminishing. In the Greater Mekong Sub-region, modifying reactive case detection from household contacts to co-workers/co-travellers and from testing to presumptive treatment of targeted contacts, could increase the impact of this approach.


2020 ◽  
Vol 3 (1) ◽  
pp. 140-144
Author(s):  
Mustafa Ali Mustafa Al-Samarrai ◽  
Ban Nadhum AL- Any ◽  
Ahmed Khalaf Soofi ◽  
Badeaa Thamer Yahyaa ◽  
Saad Ahmed Ali Jadoo

Background: Displacement in Iraq has been widespread and for frequent periods. Education was one of the most prominent victims of displacement at all levels, including higher education. This study aims to assess the impact of displacement on the psychosocial and health status of undergraduate students living in student accommodation of Anbar University, Iraq.    Methods: A retrospective cross-sectional study was conducted from 3rd to 17th April 2017. Data was collected using a universal sampling technique. A total of 355 students (Response Rate: 82.1%.) completed a self-administered questionnaire consisting of 26 close-ended questions related to the socio-demographic and economic characteristics of students. Data were analyzed using SPSS version 16. Descriptive data presented as the mean and standard deviation (±SD). Results:  The mean age (±SD) was 22.1 (±1.7) years (range 18-29). About two-third (240, 67.6%) of students experienced some mental disorders. Moreover, 25.1% of students confirmed that the mental disorders were negatively related to their level of performance in college, and the treatment was not available for 31.0% of them. Because of ID, about 45.4% of surveyed students had lost at least one academic year, and 17.5% began to smoke tobacco during the ID period. However, the social and psychological support was absent for about 57.4% of respondents. Conclusion: Our results suggest an urgent and strategic plane to improve the quality of logistics, health, and infrastructure of student accommodation.


Author(s):  
Janki Patel ◽  
Pinal Chaudhari

Introduction: The television is a landmark of scientific invention and amazing devices that has become an integral part of our life and it has revolutionized the world of communication. According to same studies children at the age of 6 years watch television daily for 3-4 hours on an average. The increasingly competitive economy is creating an environment where parents are forced to spend longer hours at work and fewer hours with their children . As result outside influences have greater access and influence over our children than ever before. The internet and media are bringing the outside world into your home . It influence the children every day and leads to the negative effects . television will escapes the children from real life and enter into a fantasy world and it inactivates the study image of schoolchildren and television will avoids the social interaction with other and alsi it’s a time consuming activity. Design: Descriptive research design. Participinats: 300 group of mothers were selected using non probability convenient sampling technique. Tool: self structured questionnaire. Result: study show that out of 300group , in pretest mean was 7.12 . The pre test standard deviation was 4.35. The mean difference was 11.33 and the obtained t-value was 16.86 which are significant at 0.005 levels. Hence, the stated hypothesis was accepted. Conclusion: Mother having poor knowledge about the impact of television viewing on behaviour 6-12 year children.


2021 ◽  
Vol 2 (2) ◽  
pp. 108
Author(s):  
Emdat Suprayitno ◽  
Zakiyah Yasin ◽  
Istiqamatul Karamah ◽  
Dian Ika Puspitasari

 Introduction: The problems in hypertension will cause emotional or mental disorders, one of which is anxiety. Feelings arise due to the fear and ignorance of an individual about hypertension experienced and the impact that will occur in the future. Psychoeducation is the provision of information about disease management and individual psychological aspects. This study aims to determine the effect of psychoeducation on the anxiety level of elderly patients with hypertension in Nambakor Village, Saronggi District.Methods: This research method is pre-experimental with the research design is one group pre test post test. The sampling technique used is Random Sampling and the number of samples is 30 respondents. Data collection using a questionnaire on the level of anxiety Depression Anxiety and Stress Scale.Result: The results showed that the mean of the anxiety score before the psychoeducation intervention was 24,43±7,60 and the mean of the anxiety score after the psychoeducation intervention was was 23,23 ± 7,83. The results of the paired t test of anxiety score was p = 0.002, means that there is significant difference in anxiety scores before and after psychoeducation.Conclusion: There is an influence of psychoeducation on the level of anxiety in the elderly with hypertension. The conclusion obtained is that psychoeducation can increase knowledge in patients with hypertension so that it is expected to be one form of intervention that can be applied. 


2015 ◽  
Vol 39 (1) ◽  
pp. 15-22 ◽  
Author(s):  
José Marcio de Mello ◽  
Henrique Ferraço Scolforo ◽  
Marcel Régis Raimundo ◽  
José Roberto Soares Scolforo ◽  
Antônio Donizette de Oliveira ◽  
...  

The sampling technique commonly used in forest inventories is the systematic sampling. This study aimed to evaluate the estimator of the variance of the mean proposed by Cochran for a systematic sampling technique in forests with high and low percentages of the sampled area. The study areas comprised native vegetation in Minas Gerais. To assess the efficiency of the estimators in situations involving high sampling rates (determined as the percentage of the area sampled), a fragment where a census was conducted was used. The remaining fragments comprised situations involving low sampling rates, and for these fragments, inventory accuracy was determined using the Cochran estimator. As a result it was observed, in the fragment where the census was conducted, that the structure of the correlation coefficient proposed by Cochran remained approximately constant for the area, and to the extent that sampling rate reduced, the impact of the Cochran estimator on the inventory accuracy decreased. For the fragments with a low sampling rate, it could be inferred that the sampling rate was a key factor for the correlation proposed by Cochran to have an impact on the forest inventory accuracy. The use of this estimator is indicated for fragments with a sampling rate greater than 10% of the area.


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