scholarly journals Stroke Risk Status, Anticoagulation Treatment, and Quality-of-Life in Chinese Patients with Atrial Fibrillation: China Registry of Atrial Fibrillation (CRAF)

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Yihong Sun ◽  
Jun Zhu ◽  
Changsheng Ma ◽  
Shaowen Liu ◽  
Yanzong Yang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Atrial Fibrillation ◽  
Stroke Risk ◽  
Chinese Patients ◽  
Tier 2 ◽  
Anticoagulant Treatment ◽  
Antiplatelet Treatment ◽  
Sf 36

Objective. To investigate the contemporary status of stroke risk profile, antithrombotic treatment, and quality-of-life (QoL) of patients with all types of atrial fibrillation (AF) in China. Design. This is a multicenter, cross-sectional study. Setting. Tertiary (80%) and Tier 2 hospitals (20%) were identified in different economic regions (Northeast, East, West, and Middle) by using a simple random sampling. Participants. A total of 3562 (85.6%) patients with nonvalvular atrial fibrillation (NVAF) and 599 (14.4%) with rheumatic valvular atrial fibrillation (VAF) were consecutively enrolled from 111 hospitals from July 2012 to December 2012. Data Collection. Patient information was collected and QoL was assessed using Short-Form 36 Health Survey (SF-36) questionnaire. Primary and Secondary Outcome Measures. The risk of stroke was assessed using the CHADS2 and CHA2DS2-VASc. QoL was assessed using Medical Outcomes Study SF-36 questionnaire. Results. Overall, 31.7% of the patients received anticoagulant treatment and 61.2% received antiplatelet treatment. The rate of anticoagulant treatment was higher in patients with VAF than in those with NVAF. The anticoagulant use was the lowest in Northeast and the highest in Middle regions. Independent risk factors associated with underuse of anticoagulants for NVAF were age, systolic blood pressure (SBP), non-Middle regions, nontertiary hospitals, and new-onset or paroxysmal AF. For VAF patients, the independent factors were age, paroxysmal AF, treatment in Tier 2 hospitals, SBP, diastolic blood pressure, history of coronary artery disease, and nonreceipt of antiarrhythmic therapy. Patients receiving anticoagulants fared significantly better in some QoL domains than those who received no antithrombotic therapy. Conclusions. These findings suggest that antiplatelet treatment is overused and anticoagulant treatment is underused both in Chinese patients with VAF and NVAF, even though usage of anticoagulants is associated with better QoL. Risk factors with underuse of anticoagulants were not identical in patients with NVAF and VAF.

Survey of Quality of Life and Related Risk Factors for a Taiwanese Village Population 3 Years Post-Earthquake

2006 ◽  
Vol 40 (4) ◽  
pp. 355-361 ◽  
Author(s):  
Hung-Chi Wu ◽  
Pesus Chou ◽  
Frank Huang-Chih Chou ◽  
Chao-Yueh Su ◽  
Kuan-Yi Tsai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Psychiatric Disorders ◽  
Short Form ◽  
Social Activity ◽  
Economic Problems ◽  
Related Risk ◽  
Sf 36 ◽  
Earthquake Survivors

Objective: To investigate quality of life (QOL) and related risk factors in Taiwanese earthquake survivors diagnosed with different psychiatric disorders 3 years after the 1999 Chi-Chi earthquake. Method: This study was a population survey. Trained assistants used the Medical Outcomes Study Short Form-36 (MOS SF-36) and questionnaires to interview 405 respondents (189 men and 216 women) aged 16 years or older, who had been exposed to the earthquake. Psychiatrists interviewed the same respondents using the Mini-International Neuropsychiatric Interview, with an adjusted response rate of 70.2%. Results: The prevalence range for psychiatric disorders in the earthquake survivors was 0.2–7.2% 3 years after the Chi-Chi earthquake, with rates for major depression (MD) and posttraumatic stress disorder (PTSD) of 6.4% and 4.4%, respectively. The QOL scores for the PTSD/MD group were lower than for the other two diagnostic groups, as determined by assessment of physical and mental aspects of functional integrity from MOS SF-36 scores. The predictors for poor QOL were age, female gender, economic problems, physical illness, subjective assessment of memory and social-activity decline and diagnosis of PTSD or MD. Conclusion: The QOL for earthquake survivors with psychiatric disorders, especially PTSD or MD, was inferior compared with the mentally healthy analogues, with contemporaneous decreases in mental and physical function scores across the QOL subscales. The persistence of long-term economic problems was one of many important factors affecting QOL.

A STUDY ON ASSESSMENT OF RISK FACTORS, COMPLICATIONS AND QUALITY OF LIFE OF PATIENTS WITH HYPOTHYROIDISM IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 38-40
Author(s):  
CH. Sridev ◽  
Samhitha Karnati ◽  
Likhitha Madari ◽  
Liyaqath Ali ◽  
Raviteja Nethula
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Care Hospital ◽  
Inclusion Criteria ◽  
Total N ◽  
Sf 36 ◽  
High Bmi

Background: Hypothyroidism is a syndrome which results from decreased production of thyroid hormones from thyroid gland and hence it can also be termed as underactive thyroid disease. Objectives: To assess the quality of life in patients with denovo hypothyroidism. To assess risk factors, complications in patients with hypothyroidism. Materials and methods: There was a total (N=100) number of participants enrolled in the study and are evaluated for risk factors and complications and among 100, 40 patients are Denovo hypothyroid who are assessed for quality of life. This is a prospective observational study in which the risk factors, complications and quality of life of patients is evaluated for those patients who are willing to give informed consent and meet the inclusion criteria. Results and Discussion: Referring to the ndings, the patients with high BMI, females and age around 20-30 are more prevalent. Patients who do not adhere to medications develop complications such as goiter and cvs problems but mostly obesity is seen and QOL of patients was studied using SF-36 and HADS scales. The initial mean was found to be less compared to the nal mean in SF-36 whereas in HADS the initial mean is high compared to the nal mean. The Patient's BMI was high initially and then reduced to normal.This implies that after educating the patient about the disease and need of medication the nal result shows there is improvement in the patient's QOL. P values of SF 36 and HADS are 0.0001 and 0.0314 respectively, which by conventional criteria was found to be statistically signicant. Conclusion: This study simply showed that the females, patients with high BMI and age around 20-30 are the major risk factors. Proper patient education, care and medication adherence are the cornerstones to help avoid complications and improve patients quality of life.

Abstract 147: Impact of Risk Factor Modification in Improving Quality of Life and Arrhythmia Symptoms in Patients With Atrial Fibrillation

2018 ◽  
Vol 11 (suppl_1) ◽  
Author(s):  
Amaryah Yaeger ◽  
Nancy R Cash ◽  
Tara Parham ◽  
Rajeev Pathak ◽  
David S Frankel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atrial Fibrillation ◽  
Risk Factor ◽  
Improve Quality ◽  
Risk Factor Modification ◽  
Obstructive Sleep ◽  
Sf 36 ◽  
The Impact ◽  
Factor Modification

Objective: The desired goal of atrial fibrillation (AF) management is maintenance of sinus rhythm in order to improve quality of life (QoL) and arrhythmia symptoms (AS). Although obesity and obstructive sleep apnea (OSA) are known risk factors for development of AF, these remain inadequately treated. We report the impact of prospectively modifying these risk factors on QoL and AS in AF patients (pts). Methods: AF pts with obesity (body mass index (BMI) ≥30kg/m 2 ) and/or the need for OSA management (high-risk as per Berlin Questionnaire or untreated OSA) were voluntarily enrolled in a nurse-led risk factor modification (RFM) program at their arrhythmia clinic visit. RFM entailed patient education, lifestyle modification counseling, coordination of care with appropriate specialists, and longitudinal care management. Progress with weight loss (WL) and OSA treatment was monitored via monthly follow-up calls and/or downloads from continuous positive airway pressure (CPAP) units for up to 12 months. QoL and AS were determined with the SF-36 and AF Severity Scale (AFSS) respectively, and were assessed at baseline, 6 months, and 12 months. Student t-test and chi-square tests were used to compare continuous and dichotomous variables. Results: From 11/1/16 to 10/31/17, 252 pts (age 63±11 years; male=179; paroxysmal AF=126) were enrolled as follows: 189 for obesity and 93 for OSA. The mean WL was 2.7±3.8% from baseline and 78% (n=126 of 162 pts with available data) of enrolled obese patients achieved WL. Among 93 pts at risk for OSA, 70 completed sleep studies and 50 were identified with OSA. Majority of these patients (76%; n=38 of 50) started CPAP therapy and have remained full (57%; n=17 of 30 pts with available CPAP data) and partial (13%; n=4 of 30) users. Table shows that SF-36 and AFSS scores improved for most measures of QoL and AS from baseline to 6 months. Conclusion: Participation in a risk factor modification program targeting obesity and obstructive sleep apnea can improve quality of life and arrhythmia symptoms in patients with atrial fibrillation. The impact of this strategy on long-term maintenance of sinus rhythm remains to be determined.

Heart Failure is Associated With Worse Quality of Life and Survival But Similar Stroke Risk in Atrial Fibrillation

2015 ◽  
Vol 21 (8) ◽  
pp. S115-S116
Author(s):  
Tharian S. Cherian ◽  
Peter Shrader ◽  
Gregg C. Fonarow ◽  
Larry A. Allen ◽  
Eric D. Peterson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Atrial Fibrillation ◽  
Stroke Risk

scholarly journals Health-related quality of life of COVID-19 survivors at 6 months after hospital discharge: a cohort study

2021 ◽  
Author(s):  
MeiXuan Lin ◽  
Liqun Huang ◽  
Danwen Zheng ◽  
Linjie Zhang ◽  
Bing Feng ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cognitive Function ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Abstract Background: COVID-19 is a multi-systemic disease that is highly contagious and pathogenic. The long-term consequences of it are not yet clear, as is whether society and life can return to a healthy state. Long-term assessment of their health-related quality of life (HRQoL) is essential. This study aimed to investigate HRQoL and its risk factors in COVID-19 survivors at a follow-up of 6-month. Methods: A multicenter cross-sectional survey was conducted among 192 COVID-19 patients with confirmed age ≥ 18 years who were discharged from various hospitals in Wuhan from January to April 2020. The demographic characteristics, clinical characteristics, and laboratory results of the study subjects were obtained from the hospital's medical records. Survivors' HRQoL was assessed using the Short Form 36 (SF-36), cognition was assessed using the ascertain dementia eight-item informant questionnaire (AD8), and survivors' pulmonary function were examined. All participants in this study completed the survey and testing at Hubei Provincial Hospital of Chinese and Western Medicine. SF-36 scores were compared with the Chinese norm, and logistic regression and multivariate analysis were used to investigate the factors affecting HRQoL in COVID-19 survivors. Results: SF-36 showed significant differences in HRQoL between COVID-19 survivors and the general Chinese population ( P< 0.05).Multiple linear regression demonstrated that age was negatively correlated with physical functioning (PF), role-physical limitation (RP) and social functioning (SF) ( P <0.05). Bodily pain (BP), vitality (VT), SF and role-emotional limitation (RE) were negatively correlated with females ( P <0.05). Length from discharge to follow‐up was positively correlated with PF and RP ( P <0.05). Abnormal cognitive function was negatively correlated with PF, RP, general health (GH), VT, SF, RE and mental health (MH) ( P <0.05). Abnormal Carbon Monoxide Diffusing Capacity (DLCO%<80%) was significantly negatively correlated with PF and SF ( P <0.05).In addition, there was a significant negative correlation between Coronary heart disease and RP, GH, VT and RE ( P <0.05).Logistic regression analysis demonstrated that age(OR 1.032) and AD8 scores (OR 1.203)were risk factors associated with a low physical component summary (PCS) score. Length from discharge to follow‐up (OR 0.971) was the protective factor for PCS score. Abnormal cognitive function (OR 1.543) was a significant determinant associated with a mental component summary (MCS)<50 in COVID-19 patients. Conclusions: The HRQoL of COVID-19 survivors remains to be improved at six-month follow-up. Future studies should track HRQoL in older adults, women, patients with abnormal DLCO, and abnormal cognitive function for a long time and provide them with rehabilitation advice and guidance.

scholarly journals Asociación entre los niveles de actividad física, calidad de vida y comorbilidades en la hipertensión en una ciudad del estado de São Paulo

2019 ◽  
Vol 0 (Avance Online) ◽  
Author(s):  
Grace Fernanda Nunes ◽  
Luis Cuadrado Martins ◽  
Roberto Jorge da Silva Franco ◽  
Ivani Morales Xavier ◽  
Monica Marcelli de Souza ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Sao Paulo ◽  
São Paulo ◽  
Calidad De Vida ◽  
Sf 36 ◽  
Factores De Riesgo

Resumo Objetivo: Avaliar a associação entre nível de atividade física e fatores de risco cardiovascular, qualidade de vida e comorbidades dos pacientes hipertensos em Agudos (São Paulo - Brasil). Método: Foram avaliados 200 pacientes hipertensos e verificadas as associações entre Questionário Internacional de Atividade Física IPAQ, questionário de qualidade de vida SF-36, fatores de risco cardiovascular e comorbidades. Resultados: O nível de atividade física associou-se à qualidade de vida nos domínios capacidade funcional, limitações físicas e estado geral de saúde. Houve associação entre o nível de atividade física e qualidade de vida, mesmo ajustando-se para as variáveis de confusão (idade, sexo, profissão, acidente vascular encefálico prévio, internação previa por insuficiência cardíaca congestiva e diabetes). Conclusão: O nível de atividade física em hipertensos e diabéticos foi inferior ao desejado e associou-se a fatores de risco cardiovascular, comorbidades e vários indicadores de qualidade de vida. Resumen Objetivo: Evaluar la asociación entre nivel de actividad física y factores de riesgo cardiovascular, calidad de vida y comorbilidades de los pacientes del programa de atención a pacientes hipertensos en Agudos (São Paulo-Brasil). Método: 200 pacientes hipertensos fueron evaluados y se valoró la asociación entre el nivel de actividad física (mediante el Cuestionario Internacional de Actividad Física IPAQ), la calidad de vida (mediante el cuestionario SF-36), los factores de riesgo cardiovascular y las comorbilidades. Resultados: El nivel de actividad física se asoció con la calidad de vida en los ítems de capacidad funcional, limitaciones físicas y estado general de salud. Se obtuvo asociación entre el nivel de actividad física y dichos ítems de calidad de vida, independientemente de las variables de confusión (edad, sexo, profesión, accidente vascular encefálico previo, internamiento previo por insuficiencia cardíaca congestiva y diabetes). Conclusión: El nivel de actividad física en pacientes hipertensos y diabéticos fue menor de lo deseado y se asoció con factores de riesgo cardiovascular, comorbilidades y diversos indicadores de calidad de vida. Abstract Objetive: To evaluate the association between physical activity level and cardiovascular risk factors, quality of life, and comorbidities of hypertensive patients in Agudos (São Paulo-Brazil). Method: 200 hypertensive patients were evaluated and the associations between international physical activity Questionnaire IPAQ, questionnaire of quality of life SF-36, cardiovascular risk factors and comorbidities were verified. Results: The level of physical activity was associated with the quality of life in the areas functional capacity, physical limitations and general state of health. There was association between the level of physical activity and quality of life, even adjusting for the confounding variables. Conclusion: The level of physical activity in hypertensive and diabetic patients was lower than desired and was associated with cardiovascular risk factors, comorbidities and several indicators of quality of life.

scholarly journals Stroke risk and its association with quality of life: a cross-sectional study among Chinese urban adults

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Huiqing Yao ◽  
Juhua Zhang ◽  
Yanmei Wang ◽  
Qingqing Wang ◽  
Fei Zhao ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Relative Risk ◽  
High Risk ◽  
Psychosocial Factors ◽  
Stroke Risk ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Stroke is a leading cause of mortality and disability worldwide. Most stroke risk studies focused on more established biological and pathophysiological risk factors such as hypertension and smoking, psychosocial factors such as quality of life are often under-investigated and thus less reported. The current study aims to estimate stroke risk and explore the impact of quality of life on stroke risk among a community sample of urban residents in Shanghai. Methods This cross-sectional study was conducted in Fengxian District of Shanghai City from December 2018 to April 2019. 4030 representative participants were recruited through a multistage, stratified, probability proportional to size sampling method and completed the study. Stroke risk was assessed using the Rapid Stroke Risk Screening Chart that included 8 risk factors for stroke. Quality of life was measured using the World Health Organization Quality of Life-brief version (WHOQOL-BREF). Results One-third of residents were at risk for stroke, including 14.39% at high risk, and 18.68% at middle risk. The top three most commonly reported risk factors were physical inactivity (37.30%), hypertension (25.38%), and smoking (17.32%). Quality of life and its four domains were all independently and significantly associated with stroke risk. Multinominal logistic regressions showed that a one-unit increase in the quality of life was associated with a decreased relative risk for middle-risk relative to low-risk of stroke by a factor of 0.988 (95% CI:0.979, 0.997, P = 0.007), and a decreased relative risk for high-risk relative to low-risk of stroke by a factor of 0.975 (95% CI:0.966, 0.984, P < 0.001). Conclusions Our findings showed an alarmingly high prevalence of stroke risk among the sample, which may require future intervention programs to focus on improving both biological and behavioral risk factors such as increasing physical activity, early diagnosis and treatment of hypertension, and smoking cessation, as well as improving psychosocial factors such as quality of life.

scholarly journals Poor quality of life is associated with obesity and sedentary life style in atherosclerotic disease: a cross-sectional study / A má qualidade de vida está associada à obesidade e ao estilo de vida sedentário na doença aterosclerótica: um estudo transversal

2021 ◽  
Vol 4 (5) ◽  
pp. 20118-20131
Author(s):  
Elisa Maia Dos Santos ◽  
Grazielle Vilas Bôas Huguenin ◽  
Paulo Rogério Melo Rodrigues ◽  
Bernardete Weber ◽  
Annie Seixas Bello De Moreira
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Risk Factors ◽  
Cross Sectional Study ◽  
Poor Quality ◽  
Atherosclerotic Disease ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sf 36

The Health-related quality of life (HRQoL) is an important measure of the health status of a population. It can be related to nutritional status and risk factors of cardiovascular disease.This study aimed to assess the quality of life and the association with nutritional status and other modifiable risk factors in patients with atherosclerotic disease.This is a cross-sectional study carried out in two public health centers in Rio de Janeiro, Brazil. A total of 273 participants with a documented history of atherosclerotic disease in the last ten years from their entry to the study. Quality of life (SF-36 questionnaire); physical activity; food intake (food frequency questionnaire), blood pressure; anthropometric and biochemical measures were assessed. Poor quality of life scores were identified, women had lower scores (p0.05) for all SF-36 domains. Obesity was associated with a decreased score of SF-36 physical and mental health domains. Sedentary lifestyle was associated with poorer quality of life in almost all domains assessed. The adoption of healthy weight and appropriate physical activity was associated with better quality of life in patients with atherosclerotic disease.

scholarly journals Impact of initial rhythm control with cryoballoon ablation versus drug therapy on atrial fibrillation recurrence and quality of life: results from the Cryo-FIRST study

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
N Pavlovic ◽  
M Kuniss ◽  
V Velagic ◽  
JS Hermida ◽  
S Healey ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atrial Fibrillation ◽  
Summary Score ◽  
Group Differences ◽  
Cryoballoon Ablation ◽  
First Line ◽  
Significant Group ◽  
Sf 36 ◽  
Af Recurrence

Abstract Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Medtronic OnBehalf The Cryo-FIRST Investigators Background Cryoballoon ablation (CBA) as a first-line rhythm control strategy is superior to antiarrhythmic drugs (AADs) for preventing atrial arrhythmia recurrence; however, the impact of first-line CBA specifically on atrial fibrillation (AF) recurrence and quality of life (QoL) has not been well characterized. Purpose To compare AF recurrence and QoL following first-line CBA vs. AAD therapy in patients with paroxysmal AF within the CryoFIRST trial (NCT01803438). Methods Patients with recurrent symptomatic paroxysmal AF who had not been administered class I or III AAD therapy for &gt;48 hours were enrolled at 18 sites in 9 countries. Patients were randomized (1:1) to CBA or AAD treatment (Class I or III). Subjects were followed by 7-day Holter at 1, 3, 6, 9, and 12 months. Time-to-first AF recurrence outside of a 90-day blanking period was estimated by Kaplan-Meier analysis.  QoL was evaluated using the Atrial Fibrillation Effect on Quality of Life (AFEQT) and 36-Item Short Form Health Survey (SF-36) v2 questionnaires. Results Of the 218 randomized subjects, 187 (86%) completed the 12-month follow-up. By intention-to-treat (ITT) analysis, freedom from AF after blanking was achieved in 86.6% in the CBA and 74.5% in the AAD group (p = 0.023).  There was no difference in the time-to-first serious adverse event between groups. In total, 84.3% of patients in the CBA vs. 75.0% of patients in the AAD arm had a clinically important improvement (≥5 points) in the AFEQT summary score.  The adjusted mean difference in the AFEQT summary score at 12 months was 9.9 points higher in the CBA group (95% CI: 5.5-14.2; P &lt; 0.001).  All AFEQT subscale scores were more favorable in the CBA vs. AAD group at 12 months.  There were no significant group differences in any of the SF-36 health domain scores at 12 months in the ITT analysis.  In the per-protocol analysis, clinically important and significant group differences in favor of CBA were observed at 12 months for 3 of 8 SF-36 health domain scores (physical functioning, general health and social functioning). Conclusion CBA is superior to AAD for preventing AF recurrence and improving AF-specific QoL in patients with paroxysmal AF. AFEQT Scores at Baseline and 12 MonthsAFEQT Score, Mean ± Standard DeviationCBAAADAdjusted Mean Difference at 12 Months (CBA vs. AAD)p-valueBaseline12 MonthsBaseline12 MonthsDaily Activities65.3 ± 25.887.8 ± 17.161.0 ± 27.976.6 ± 25.48.9 (3.2-14.6)0.002Symptoms59.9 ± 24.888.8 ± 15.658.4 ± 25.280.9 ± 22.27.1 (1.5-12.7)0.014Treatment Concern59.9 ± 23.189.8 ± 14.060.4 ± 24.577.7 ± 22.212.7 (7.9-17.5)&lt;0.001AFEQT, Atrial Fibrillation Effect on Quality of Life questionnaire. CBA, cryoballoon ablation. AAD antiarrhythmic drug.Abstract Figure. Freedom From Atrial Fibrillation

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