Large Bowel Endometriosis Mimicking Colorectal Cancer

Endometriosis is characterized by the presence of endometrial tissue outside the uterus, with 1–7% prevalence in the female population. It is observed in various locations of the human body, and large bowel endometriosis is the most common extrapelvic site, affecting about 5 to 12% of all women who present endometriosis. This study aimed to report an interesting images related to stenosing large bowel endometriosis that was possible to be diagnosed only by surgical intervention. Hence, this pathology is a diagnostic challenge and should be remembered between differential diagnoses of nonspecific or even alarming symptoms of the gastrointestinal tract.

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IgG4-related intracranial disease

The Neuroradiology Journal ◽

10.1177/1971400918806323 ◽

2018 ◽

Vol 32 (1) ◽

pp. 29-35 ◽

Cited By ~ 6

Author(s):

Shahine Goulam-Houssein ◽

Jeffrey L Grenville ◽

Katerina Mastrocostas ◽

David G Munoz ◽

Amy Lin ◽

...

Keyword(s):

Plasma Cells ◽

Surgical Intervention ◽

Case Series ◽

Hypertrophic Pachymeningitis ◽

Diagnostic Challenge ◽

Perineural Spread ◽

Related Disease ◽

The Third ◽

Igg4 Related Disease ◽

Intracranial Involvement

IgG4-related disease (IgG4-RD) is a multi-organ chronic inflammatory process caused by infiltration of IgG4-positive plasma cells in one or more organs. Intracranial involvement has only recently become better recognized. Our case series adds to the growing literature on the varying presentations of intracranial IgG4 by describing the clinical and imaging findings of three patients who presented to our institution with intracranial involvement. Our first patient presented with a mass-forming IgG4 pachymeningitis mimicking a sphenoid wing meningioma, which is to our knowledge the largest mass-forming pachymeningitis published in the literature. Our second case depicts another presentation of extensive IgG4 pachymeningitis involving both cavernous sinuses and surrounding Meckel’s caves. The third case describes a patient with presumed lymphocytic hypophysitis, which was later determined to be IgG4-related hypophysitis with concomitant pachymeningitis and perineural spread along the optic nerves. The delayed diagnoses in our cases illustrates the diagnostic challenge that clinicians face in differentiating intracranial IgG4-RD from other infiltrative diseases such as sarcoidosis, granulomatous disease, tuberculosis and lymphoma. Earlier consideration of IgG4-related hypophysitis and hypertrophic pachymeningitis in the differential diagnosis can prevent significant morbidity including unnecessary surgical intervention and organ failure secondary to extensive fibrosis.

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Early radical cystectomy with negative margins in a 57-year-old female with myxoid/round cell liposarcoma of the bladder suggests prolonged overall survival

African Journal of Urology ◽

10.1186/s12301-021-00152-y ◽

2021 ◽

Vol 27 (1) ◽

Author(s):

Johannes Eduard Delport ◽

Khanyisa Makamba

Keyword(s):

Overall Survival ◽

Surgical Intervention ◽

Radical Surgery ◽

Bladder Tumour ◽

Eastern Cape ◽

Round Cell ◽

Female Population ◽

Case Presentation ◽

Rural Town ◽

Common Cancer

Abstract Background Bladder cancer is the 17th most common cancer in the female population. Most bladder cancers are of urothelial origin. Sarcomas of the bladder are very uncommon. Case presentation This case concerns a 57-year-old female from a rural town in the Eastern Cape who was diagnosed with myxoid/round cell liposarcoma of the bladder. After the initial transurethral resection of the bladder tumour, she underwent an anterior exenteration with Bricker’s diversion (ileal conduit) and negative margins were achieved. Conclusions Sarcomas of the bladder are known to have a poor prognosis. Our patient is alive with good stoma function more than 24 months since her radical surgery. We are of the opinion that her favourable overall survival is attributable to early radical surgical intervention with negative margins.

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A Crosstalk between Diet, Microbiome and microRNA in Epigenetic Regulation of Colorectal Cancer

Nutrients ◽

10.3390/nu13072428 ◽

2021 ◽

Vol 13 (7) ◽

pp. 2428

Author(s):

Małgorzata Guz ◽

Witold Jeleniewicz ◽

Anna Malm ◽

Izabela Korona-Glowniak

Keyword(s):

Colorectal Cancer ◽

Gastrointestinal Tract ◽

Gut Microbiota ◽

Intestinal Microbiota ◽

Current Knowledge ◽

Vital Role ◽

Disease States ◽

Health And Disease ◽

Dietary Components ◽

Non Coding Rnas

A still growing interest between human nutrition in relation to health and disease states can be observed. Dietary components shape the composition of microbiota colonizing our gastrointestinal tract which play a vital role in maintaining human health. There is a strong evidence that diet, gut microbiota and their metabolites significantly influence our epigenome, particularly through the modulation of microRNAs. These group of small non-coding RNAs maintain cellular homeostasis, however any changes leading to impaired expression of miRNAs contribute to the development of different pathologies, including neoplastic diseases. Imbalance of intestinal microbiota due to diet is primary associated with the development of colorectal cancer as well as other types of cancers. In the present work we summarize current knowledge with particular emphasis on diet-microbiota-miRNAs axis and its relation to the development of colorectal cancer.

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Tu1689 - Long-Term Outcomes of Colorectal Cancer Patients with and without Malignant Large-Bowel Obstruction

Gastroenterology ◽

10.1016/s0016-5085(18)34425-1 ◽

2018 ◽

Vol 154 (6) ◽

pp. S-1352

Author(s):

Riku Yamamoto ◽

Shinya Munakata ◽

Tomoyuki Kushida ◽

Hajime Orita ◽

Mutsumi Sakurada ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Bowel Obstruction ◽

Large Bowel ◽

Large Bowel Obstruction ◽

Long Term Outcomes ◽

Colorectal Cancer Patients

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Isolated Duodenal Crohn's Disease: A Case Report and a Review of the Surgical Management

Case Reports in Surgery ◽

10.1155/2013/421961 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Faruk Karateke ◽

Ebru Menekşe ◽

Koray Das ◽

Sefa Ozyazici ◽

Pelin Demirtürk

Keyword(s):

Crohn’S Disease ◽

Case Report ◽

Gastrointestinal Tract ◽

Crohn's Disease ◽

Medical Treatment ◽

Immunosuppressive Therapy ◽

Surgical Management ◽

Surgical Intervention ◽

Surgical Options ◽

Crohn’S Diseases

Crohn's disease may affect any segment of the gastrointestinal tract; however, isolated duodenal involvement is rather rare. It still remains a complex clinical entity with a controversial management of the disease. Initially, patients with duodenal Crohn' s disease (DCD) are managed with a combination of antiacid and immunosuppressive therapy. However, medical treatment fails in the majority of DCD patients, and surgical intervention is required in case of complicated disease. Options for surgical management of complicated DCD include bypass, resection, or stricturoplasty procedures. In this paper, we reported a 33-year-old male patient, who was diagnosed with isolated duodenal Crohn’s diseases, and reviewed the surgical options in the literature.

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Addiction to medical aesthetic procedures

Studia Gdańskie. Wizje i rzeczywistość ◽

10.5604/01.3001.0014.3173 ◽

2018 ◽

Vol XIV ◽

pp. 233-249

Author(s):

Jolanta Kozaczyńska

Keyword(s):

Social Functioning ◽

Human Body ◽

Surgical Intervention ◽

Common Phenomenon ◽

Aesthetic Medicine ◽

Utopian Vision ◽

Frequent Contact ◽

The Media ◽

Body Shapes ◽

Aesthetic Procedures

Today’s media disseminate a narcissistic cultivation of beauty and promote a focus mainly on appearance and satisfaction from its improvement. The human body assumes a form in the media that is often impossible to achieve without surgical intervention. When people are in frequent contact with a utopian vision of the perfect body, this can lead to many disorders in both social functioning and self-perception. In extreme cases, striving to preserve beauty and youth may lead to an addiction to aesthetic medicine treatments. It is an increasingly common phenomenon. People who are addicted to treatments improving their beauty or changing their body shapes are not aware of the problem that affects them. They lose their rational judgement and their assessment is far from the opinions of people around them and socially accepted norms. All signs of concern from others are perceived as an attack on their independence and this further deepens their sense of loneliness and isolation from society. With time, undergoing further beautifying procedures becomes the only way they know to achieve a momentary sense of happiness.

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A case of colonic gallstone ileus with a spontaneous evacuation

Health Renaissance ◽

10.3126/hren.v9i1.4363 ◽

1970 ◽

Vol 9 (1) ◽

pp. 47-49 ◽

Cited By ~ 1

Author(s):

A Bajracharya ◽

OP Pathania ◽

S Adhikary ◽

CS Agrawal

Keyword(s):

Bowel Obstruction ◽

Large Bowel ◽

Gallstone Ileus ◽

Abdominal Distension ◽

The Elderly ◽

Large Bowel Obstruction ◽

High Morbidity ◽

Diagnostic Challenge ◽

History Of ◽

Spontaneous Evacuation

Colonic gallstone is an uncommon entity with a high morbidity and mortality due to various reasons. It remains a diagnostic challenge because of delayed and non-specific presentations, especially in the elderly population, often with multiple co-morbidities. We present a case of colonic gallstone ileus with spontaneous evacuation in a 67 years female who had a threeday history of intermittent bouts of colicky abdominal pain, vomiting , constipation and progressive abdominal distension, features of large bowel obstruction treated non operatively for 72 hours and passage of the stone spontaneously. Keywords: gallstone ileus; large bowel obstruction; colonic gallstone DOI: 10.3126/hren.v9i1.4363Health Renaissance, 2011: Vol.9 No.1:47-49

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A Multiphase Flow in the Antroduodenal Portion of the Gastrointestinal Tract: A Mathematical Model

Computational and Mathematical Methods in Medicine ◽

10.1155/2016/5164029 ◽

2016 ◽

Vol 2016 ◽

pp. 1-18 ◽

Cited By ~ 4

Author(s):

P. V. Trusov ◽

N. V. Zaitseva ◽

M. R. Kamaltdinov

Keyword(s):

Mathematical Model ◽

Gastrointestinal Tract ◽

Multiphase Flow ◽

Human Body ◽

Digestive System ◽

System Model ◽

Food Density ◽

Secretory Function ◽

Functional Disorders ◽

Food Particles

A group of authors has developed a multilevel mathematical model that focuses on functional disorders in a human body associated with various chemical, physical, social, and other factors. At this point, the researchers have come up with structure, basic definitions and concepts of a mathematical model at the “macrolevel” that allow describing processes in a human body as a whole. Currently we are working at the “mesolevel” of organs and systems. Due to complexity of the tasks, this paper deals with only one meso-fragment of a digestive system model. It describes some aspects related to modeling multiphase flow in the antroduodenal portion of the gastrointestinal tract. Biochemical reactions, dissolution of food particles, and motor, secretory, and absorbing functions of the tract are taken into consideration. The paper outlines some results concerning influence of secretory function disorders on food dissolution rate and tract contents acidity. The effect which food density has on inflow of food masses from a stomach to a bowel is analyzed. We assume that the future development of the model will include digestive enzymes and related reactions of lipolysis, proteolysis, and carbohydrates breakdown.

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Outcome of Acute Burn Injuries in a Tertiary Care Centre of Kathmandu Nepal

Journal of Institute of Medicine ◽

10.3126/jiom.v42i2.37533 ◽

2020 ◽

Vol 42 (2) ◽

pp. 33-36

Author(s):

Manish Devkota ◽

Samit Sharma ◽

Sangam Rayamajhi ◽

Jayan M Shrestha ◽

Ishwar Lohani

Keyword(s):

Low Income ◽

Surgical Intervention ◽

Burn Injury ◽

Tertiary Care ◽

Total Body Surface Area ◽

Burn Injuries ◽

Low Income Countries ◽

Female Population ◽

Partial Thickness Burn ◽

Flame Burn

Introduction Burn injuries are associated with higher morbidity and mortality especially in middle and low-income countries. The objective of the study is to assess the outcome of acute burn injuries in a tertiary care center of Kathmandu, Nepal. MethodsThis is a descriptive cross-sectional study of the clinical data of acute burn patients admitted from January 2016-December 2018. ResultsOut of 124 patients with burn injuries, there were more females (n=65, 52.4 %) than males (n=59, 47.6%). Flame burn was the most common mode of injury (n=71,57.3 %) followed by scald (n=22,17.7 %). Thirty-eight (30.6%) patients arrived to hospital on the same day of injury. The average time required to reach our hospital was 24 hours. The most frequently involved site was lower extremities (n=40, 32.26%) followed by upper extremities (n=33, 26.62%). Total body surface area (TBSA) involved in the burn injury ranges from 10% to 50% with a median of 15%. Hospital stay was 14 to 58 days with a median of 17 days. Partial thickness burn was seen in 114 (91.94%) patients whereas 10 (8.06%) patients had full thickness burn. Surgical intervention was needed in 71 (57.26%) patients. Among 71 patients, 12 patients underwent surgery twice. Fifty-two (41.94%) patients were managed conservatively. The mortality rate was 4.03%. ConclusionAdult female population is at high risk for burn injuries mostly due to flame burn. Delay in reaching care has also contributed for poor outcome of burn injuries. Majority of burn injury patients needed surgical intervention and hence improvement in surgical aspects can lead to better outcome of burn injuries.Keywords:

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