scholarly journals Pain Perception, Brain Connectivity, and Neurochemistry in Healthy, Capsaicin-Sensitive Subjects

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Stefanie Heba ◽  
Matthias Sczesny-Kaiser ◽  
Kirsten Sucker ◽  
Jürgen Bünger ◽  
Thomas Brüning ◽  
...  
Keyword(s):  
Pain Perception ◽  
Negative Impact ◽  
Brain Connectivity ◽  
Cognitive Task ◽  
Health Assessment ◽  
Well Being ◽  
Airway Hyperreactivity ◽  
Mechanical Stimuli ◽  
Exposure Limits ◽  
Increased Risk

Most of the occupational exposure limits (OELs) are based on local irritants. However, exposure to much lower concentrations of irritant substances can also lead to health complaints from workers. Exposure to irritants is often accompanied by strong unpleasant odors, and strong odors might have distracting effects and hence pose a safety risk. The findings obtained in human exposure studies with chemically sensitive, stressed, or anxious persons suggest that their ability to direct attention away from the odorous exposure and to focus on a cognitive task is reduced. In addition, after repeated odor exposure, these persons show signs of sensitization, i.e., difficulties in ignoring or getting used to the exposure. The question arises as to whether certain health conditions are accompanied by a change in sensitivity to odors and irritants, so that these persons are potentially more distracted by odors and irritants and therefore more challenged in working memory tasks than nonsusceptible persons. In our study, susceptible persons with sensory airway hyperreactivity (“capsaicin-sensitive”) respond more strongly to mechanical skin stimuli than controls and show altered network connectivity. Capsaicin-sensitive subjects have a lower pain threshold and thus are more sensitive to mechanical skin stimuli. The intrinsic functional connectivity of their saliency network is higher, and the lower the GABAergic tone of the thalamus, the higher their pain sensitivity to mechanical stimuli. It seems that the increased communication between resting-state networks promotes a stronger perception of the sensory input signal. The results can be used to inform about actual risks (i.e., attention diversion and increased risk of accidents) and “pseudo” risks such as odor perception without a negative impact on one’s well-being. This way, uncertainties that still prevail in the health assessment of odorous and sensory irritating chemicals could be reduced.

scholarly journals The Social and Health Impact of Accidents at Work: The Analysis of the Italian Case

2021 ◽  
Author(s):  
Di Romano Benini
Keyword(s):  
Risk Factors ◽  
Negative Impact ◽  
Well Being ◽  
Health Impact ◽  
Work Culture ◽  
Organizational Models ◽  
Work Related ◽  
Italian Case ◽  
Increased Risk ◽  
Related Stress

The months of a gradual exit from the pandemic show some significant data and phenomena regarding the phenomenon of accidents at work and occupational diseases. The Italian figure highlights a recovery in injuries and illnesses, but also in the impact of new risk factors deriving from the digitalization of work, which grew with smart working during the pandemic. At the same time, the new organizational models highlight the increased risk of work-related stress diseases. The Italian situation makes clear the need to intervene on the issue of organizational well-being and welfare, to limit the negative impact of risk factors associated with this economic system on society and the health system through a new work culture.

scholarly journals Abusive Supervision: A Systematic Review and New Research Approaches

2022 ◽  
Vol 6 ◽  
Author(s):  
Ivonne Gallegos ◽  
Joan Guàrdia-Olmos ◽  
Rita Berger
Keyword(s):  
Negative Impact ◽  
Meta Analysis ◽  
Abusive Supervision ◽  
Well Being ◽  
Economic Damage ◽  
Cross Sectional ◽  
Theoretical Approaches ◽  
Supervision Process ◽  
Increased Risk ◽  
New Research

Abusive leaders affect employees’ emotions and health and produce counterproductive behaviors that cause economic damage to organizations. The literature has focused predominantly on the antecedents of abusive supervision and its negative impact, providing knowledge on mechanisms that link abusive supervision to consequences for subordinates. There has been limited research on the supervisor perspective, on the group level, and on recovery. This review makes three contributions: first, we examine the theoretical approaches used by previous research studies to understand abusive supervision. Second, we analyze the types of mechanisms that explain how and when an abusive supervision process occurs. Third, we identify and discuss applied methodologies and limitations. Based on the preferred reporting items for systematic reviews and meta-analysis guidelines, and transactional well-being process perspective, we analyzed 171 empirical manuscripts and 239 samples between 2010 and July 2020. We identified a growth in abusive supervision research between 2018 and 2020 and found 101 different theories. Most of these theories view abusive supervision from a social, relational, or affective perspective, but seldom from an emotional perspective. We classified four types of mechanisms: simple relations between abusive supervision and antecedent-consequences (12), moderators (47), mediators (26), and a combination of mediators and moderators (86). We found that research has mostly been performed at the employee level or on dyads; studies that analyze the team level are rarely found. We identified two methodological problems: cross-sectional designs, which do not allow the analysis of its causality, and the increased risk of common method variance that may influence the results obtained via single-source data. In conclusion, the theories used have focused on employee perceptions, which have not enabled the broadening of the abusive supervision concept to include the supervisor’s perspective and a recovery-related perspective. Research on how and when abusive supervision occurs analyzed with complex mechanisms using emotional variables and appropriate daily methodologies has been scarce. We propose a theoretical expansion including emotional theories to uncover emotional consequences of abusive supervision and the recovery concept to provide a deeper insight into abusive supervision process. We contend that longitudinal and diary designs that include teams and supervisor levels are necessary.

scholarly journals Beyond PPE: a mixed qualitative–quantitative study capturing the wider issues affecting doctors’ well-being during the COVID-19 pandemic

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e050223
Author(s):  
Lyndsey Jayne Cubitt ◽  
Yu Ri Im ◽  
Ciaran James Scott ◽  
Louise Claire Jeynes ◽  
Paul David Molyneux
Keyword(s):  
Mental Health ◽  
Online Survey ◽  
Negative Impact ◽  
Positive Impact ◽  
Working Hours ◽  
Well Being ◽  
Physical And Mental Health ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Increased Risk

The COVID-19 pandemic has brought unprecedented challenges to the medical workforce. This has put them at increased risk of burnout at a time when levels are already worryingly high in the profession, with recent studies consistently showing that around half of doctors meet the validated criteria for burnout.ObjectivesTo understand the wider factors influencing and impacting upon hospital doctors’ well-being during the COVID-19 pandemic in England.DesignCross-sectional survey and mixed quantitative–qualitative analysis.SettingAcute National Health Service (NHS) Foundation Trust in England.ParticipantsAn online survey was circulated in early June 2020 to all 449 doctors employed by the Trust. 242 doctors completed the survey (54% response rate).Primary outcome measuresQuestions assessed occupational details, self-reported changes in physical and mental health, satisfaction with working hours and patterns, availability of personal protective equipment (PPE), medication and facilities, communication and sought to identify areas seen as having a significant effect on doctors’ well-being.Results96% of respondents requiring PPE were able to access it. Nearly half of the respondents felt that their mental health had deteriorated since the start of the pandemic. Over a third stated that their physical health had also declined. Issues identified as having a negative impact on doctors included increased workload, redeployment, loss of autonomy, personal issues affecting family members, anxiety around recovery plans, inadequate access to changing and storage facilities and to rest areas that allow for social distancing. Doctors appreciated access to ‘calm rooms’ that were made available for staff, access to clinical psychology support, free drinks and free car parking on site.ConclusionThe emerging themes are suggestive of increased burnout risk among doctors during the COVID-19 pandemic and encompass factors well beyond shortage of PPE. Small organisational initiatives and the implementation of changes suggested by survey respondents can have a positive impact on doctors’ well-being.

scholarly journals Possible toxicity of chronic carbon dioxide exposure associated with mask use, particularly in pregnant women, children and adolescents – a scoping review

2022 ◽  
Author(s):  
Kai Kisielinski ◽  
Susanne Wagner ◽  
Oliver Hirsch ◽  
Bernd Klosterhalfen ◽  
Andreas Prescher
Keyword(s):  
Experimental Data ◽  
Carbon Dioxide ◽  
Pregnant Women ◽  
Children And Adolescents ◽  
Animal Studies ◽  
Negative Impact ◽  
Exposure Limits ◽  
Irreversible Damage ◽  
Short Term Exposure ◽  
Increased Risk

Abstract Literature was systematically reviewed regarding CO2 exposure and facemask use. Observational and experimental data are helpful for a risk-benefit assessment for masks as a popular non-pharmaceutical intervention against SARS-CoV2 in the populace. Masks impede breathing by increasing the resistance and dead space volume leading to a re-breathing of CO2 with every breath taken. Fresh air has around 0.04% CO2, while wearing masks more than 5 minutes bears a possible chronic exposure to carbon dioxide of 1.41–3.2% of the inhaled air. Although the buildup is usually within the short-term exposure limits, long-term consequences must be considered due to experimental data. US Navy toxicity experts set the exposure limits for submarines carrying female crews to 0.8% CO2 based on animal studies indicating an increased risk for stillbirths. Additionally, in mammals chronically exposed to 0.3% CO2 experimental data demonstrates teratogenicity with irreversible damage of neurons and reduced spatial learning caused by brainstem neuron apoptosis and a reduced blood level of the insulin-like growth factor 1. With significant impact on three readout parameters (morphological, functional, marker) this chronic 0.3% CO2 exposure has to be defined as being toxic. Additional data exists on the exposure of chronic 0.3% CO2 in adolescent mammals causing neuron destruction, which includes less activity, increased anxiety and impaired learning and memory. There is a possible negative impact risk by imposing extended mask mandates especially for vulnerable subgroups. Circumstantial evidence exists that extended mask use may be related to current observations of stillbirths and to reduced verbal motor and overall cognitive performance in children born during the pandemic. Extended masking in pregnant women, children and adolescents has not been thoroughly tested and studied. As a result of the animal experimental data available, a risk-benefit analysis is urgent and a need exists to rethink mask mandates, which provide appropriate warnings.

The Effects of a Caffeine Placebo and Experimenter Expectation on Blood Pressure, Heart Rate, Well-Being, and Cognitive Performance

2001 ◽  
Vol 6 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Harald Walach ◽  
Stefan Schmidt ◽  
Yvonne-Michelle Bihr ◽  
Susanne Wiesch
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cognitive Task ◽  
Well Being ◽  
Control Group ◽  
Double Blind ◽  
Main Effect ◽  
The Difference ◽  
Being There ◽  
To Receive

We studied the effect of experimenter expectations and different instructions in a balanced placebo design. 157 subjects were randomized into a 2 × 4 factorial design. Two experimenters were led to expect placebos either to produce physiological effects or not (pro- vs. antiplacebo). All subjects except a control group received a caffeine placebo. They were either made to expect coffee, no coffee, or were in a double-blind condition. Dependent measures were blood pressure, heart rate, well-being, and a cognitive task. There was one main effect on the instruction factor (p = 0.03) with the group “told no caffeine” reporting significantly better well-being. There was one main effect on the experimenter factor with subjects instructed by experimenter “proplacebo” having higher systolic blood pressure (p = 0.008). There was one interaction with subjects instructed by experimenter “proplacebo” to receive coffee doing worse in the cognitive task than the rest. Subjects instructed by experimenter “antiplacebo” were significantly less likely to believe the experimental instruction, and that mostly if they had been instructed to receive coffee. Contrary to the literature we could not show an effect of instruction, but there was an effect of experimenters. It is likely, however, that these experimenter effects were not due to experimental manipulations, but to the difference in personalities.

Psychometric Properties of the Spontaneous and Deliberate Mind Wandering Scales

2019 ◽  
Vol 35 (6) ◽  
pp. 878-890 ◽  
Author(s):  
David Marcusson-Clavertz ◽  
Oscar N. E. Kjell
Keyword(s):  
Anxiety Disorder ◽  
Psychometric Properties ◽  
Generalized Anxiety Disorder ◽  
Social Desirability ◽  
Cognitive Task ◽  
Experience Sampling ◽  
Well Being ◽  
Mind Wandering ◽  
Generalized Anxiety ◽  
Psychological Variables

Abstract. Thinking about task-unrelated matters (mind wandering) is related to cognition and well-being. However, the relations between mind wandering and other psychological variables may depend on whether the former commence spontaneously or deliberately. The current two studies investigated the psychometric properties of the Spontaneous and Deliberate Mind Wandering Scales (SDMWS; Carriere, Seli, & Smilek, 2013 ). Study 1 evaluated the stability of the scales over 2 weeks ( N = 284 at Time 1), whereas Study 2 ( N = 323) evaluated their relations to Generalized anxiety disorder symptoms, Openness, Social desirability, and experience-sampling reports of intentional and unintentional mind wandering during an online cognitive task. The results indicated that the SDMWS were better fitted with a two-factor than a one-factor solution, although the fit was improved with the exclusion of one item. The scales exhibited strong measurement invariance across gender and time, and moderately high test-retest reliability. Spontaneous mind wandering predicted Generalized anxiety disorder and experience-sampling reports of unintentional mind wandering, whereas Deliberate mind wandering predicted Openness and experience-sampling reports of intentional mind wandering. Furthermore, Spontaneous mind wandering showed a negative association with social desirability of weak-to-medium strength. In sum, the scales generally showed favorable psychometric properties.

The role of production and non-production factors in the formation of male mortality (on the example of two Arctic single-industry towns)

2020 ◽  
Vol 60 (11) ◽  
pp. 738-741
Author(s):  
Maria S. Bryleva
Keyword(s):  
Negative Impact ◽  
Well Being ◽  
Malignant Neoplasms ◽  
Male Mortality ◽  
Occupational Factors ◽  
Copper Nickel ◽  
Production Factors ◽  
Single Industry ◽  
Working Age ◽  
Quality Of Medical Care

Introduction. One of the priority socio-economic and medical-demographic problems in Russia is the high mortality. The study aim is to identify the most significant factors that determine the mortality on the example of two single-industry towns. Materials and methods. Mortality in two single-industry towns specializing in copper-nickel production, differenced in climate, environmental, and socio-economic indicators, was studied using age-standardized indicators averaged over 8 years (2010-2017). Results. In Monchegorsk, compared to Russia, with similar non-production characteristics, working-age mortality from cardiovascular diseases (CVD) was higher by 49.0%, from malignant neoplasms (MN) by 34.7%, from diseases of the digestive system by 35.5%, which confirms the negative impact of occupational factors on the mortality of the population of a single-industry city. In Norilsk city, with the worst characteristics of the environment and climate, compared to Monchegorsk, mortality from CVD was lower in working age by 40.6%, in post-working age by 41.4%; from MN - in working age lower by 37.2% that shows the compensating influence of socio-economic factors on mortality. Conclusion. Risk factors for increased mortality rates in single-industry towns with copper-nickel enterprises are the influence of harmful occupational factors, as well as environmental pollution. Along with primary prevention, an effective mechanism for reducing mortality is to improve socio-economic well-being, and the quality of medical care.

The impact of the COVID-19 pandemic on the psychosocial condition of students in Poland and Ukraine

2020 ◽  
Author(s):  
Piotr Długosz ◽  
Yana
Keyword(s):  
Distance Learning ◽  
Negative Impact ◽  
Well Being ◽  
Survey Method ◽  
Psychosocial Condition ◽  
On Line ◽  
Line Survey ◽  
The Impact ◽  
Emotional Condition ◽  
Double Measurement

The article presents the results of research on psychosocial condition among Polish and Ukrainian students during the quarantine. The aim of the research was to verify the impact of the pandemic and its accompanying phenomena on the well-being of youth. In order to achieve this goal, the CAWI on-line survey method with double measurement was used. The first measurement carried out at the beginning of the quarantine resulted in 3659 filled out surveys in Poland and 739 in Ukraine. The second measurement conducted at the end of distance learning brought 1978 filled out surveys in Poland and 411 in Ukraine. The results of research indicate that the quarantine had a negative impact on the psychosocial condition of youth. The deterioration of emotional condition and the increase in mental disorders has been observed. Due to the pandemic and distance learning, the mental health of youth deteriorated significantly. Polish youth were negatively influenced by the pandemic to a greater extent than young Ukrainians.

scholarly journals Eye Movements in Response to Pain-Related Feelings in the Presence of Low and High Cognitive Loads

2020 ◽  
Vol 10 (5) ◽  
pp. 92
Author(s):  
Ramtin Zargari Marandi ◽  
Camilla Ann Fjelsted ◽  
Iris Hrustanovic ◽  
Rikke Dan Olesen ◽  
Parisa Gazerani
Keyword(s):  
Eye Movements ◽  
Cognitive Load ◽  
Eye Movement ◽  
Cognitive Processing ◽  
Pain Perception ◽  
Cognitive Task ◽  
Load Level ◽  
Task Load ◽  
Pupillary Responses ◽  
Movement Characteristics

The affective dimension of pain contributes to pain perception. Cognitive load may influence pain-related feelings. Eye tracking has proven useful for detecting cognitive load effects objectively by using relevant eye movement characteristics. In this study, we investigated whether eye movement characteristics differ in response to pain-related feelings in the presence of low and high cognitive loads. A set of validated, control, and pain-related sounds were applied to provoke pain-related feelings. Twelve healthy young participants (six females) performed a cognitive task at two load levels, once with the control and once with pain-related sounds in a randomized order. During the tasks, eye movements and task performance were recorded. Afterwards, the participants were asked to fill out questionnaires on their pain perception in response to the applied cognitive loads. Our findings indicate that an increased cognitive load was associated with a decreased saccade peak velocity, saccade frequency, and fixation frequency, as well as an increased fixation duration and pupil dilation range. Among the oculometrics, pain-related feelings were reflected only in the pupillary responses to a low cognitive load. The performance and perceived cognitive load decreased and increased, respectively, with the task load level and were not influenced by the pain-related sounds. Pain-related feelings were lower when performing the task compared with when no task was being performed in an independent group of participants. This might be due to the cognitive engagement during the task. This study demonstrated that cognitive processing could moderate the feelings associated with pain perception.

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