scholarly journals Effect of Micronutrients on Thyroid Parameters

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Hari Krishnan Krishnamurthy ◽  
Swarnkumar Reddy ◽  
Vasanth Jayaraman ◽  
Karthik Krishna ◽  
Qi Song ◽  
...  
Keyword(s):  
Amino Acids ◽  
Significant Positive Correlation ◽  
Clinical Laboratory ◽  
Serum Levels ◽  
Strong Positive Correlation ◽  
Healthy Individuals ◽  
Hormone Metabolism ◽  
Positive Correlation ◽  
Thyroid Hormone Metabolism ◽  
Iron And Zinc

Micronutrients are involved in various vital cellular metabolic processes including thyroid hormone metabolism. This study aimed to investigate the correlation between serum levels of micronutrients and their effects on thyroid parameters. The correlation of serum levels of micronutrients and thyroid markers was studied in a group of 387 healthy individuals tested for thyroid markers (T4, T3, FT4, FT3, TSH, anti-TPO, RT3, and anti-Tg) and their micronutrient profile at Vibrant America Clinical Laboratory. The subjects were rationalized into three groups (deficient, normal, or excess levels of micronutrients), and the levels of their thyroid markers were compared. According to our results, deficiency of vitamin B2, B12, and B9 and Vit-D25[OH] ( p < 0.05 ) significantly affected thyroid functioning. Other elemental micronutrients such as calcium, copper, choline, iron, and zinc ( p < 0.05 ) have a significant correlation with serum levels of free T3. Amino acids asparagine (r = 0.1765, p < 0.001 ) and serine (r = 0.1186, p < 0.05 ) were found to have a strong positive correlation with TSH. Valine, leucine, and arginine ( p < 0.05 ) also exhibited a significant positive correlation with serum levels of T4 and FT4. No other significant correlations were observed with other micronutrients. Our study suggests strong evidence for the association of the levels of micronutrients with thyroid markers with a special note on the effect of serum levels of certain amino acids.

scholarly journals A comparative study of salivary and serum calcium and alkaline phosphatase in patients with osteoporosis

2019 ◽  
Vol 7 (6) ◽  
pp. 2412
Author(s):  
Bijender Kumar Bairwa ◽  
Mamta Sagar ◽  
R. C. Gupta ◽  
Madhuri Gupta
Keyword(s):  
Alkaline Phosphatase ◽  
Comparative Study ◽  
Serum Calcium ◽  
Calcium Level ◽  
Serum Levels ◽  
Strong Positive Correlation ◽  
Medical Sciences ◽  
Easy Method ◽  
Positive Correlation ◽  
Non Invasive

Background: This study was undertaken to investigate the changes in salivary and serum calcium and alkaline phosphatase in osteoporosis patients. The objective was to compare the change in serum levels with those in saliva.Methods: The study was conducted in the department of biochemistry, National Institute of Medical Sciences and Hospital, Shobha Nagar, Jaipur, Rajasthan, India. Subjects were selected from department of orthopedics, National Institute of Medical Sciences and Hospital, Shobha Nagar, Jaipur, Rajasthan, India. At the same time one hundred adult osteoporosis patients confirmed by DEXA were taken. Calcium and alkaline phosphatase were measured in serum and saliva of each patient. The data obtained was statistically analyzed.Results: Serum calcium has strong positive correlation with salivary calcium (r=0.726) while serum ALP and salivary ALP had weak positive correlation (r =0.453).Conclusions: Saliva can be used to measure calcium level instead of serum as it is non-invasive, quick and easy method.

THE EFFECT OF SENSORIMOTOR RHYTHM ENHANCING NEUROFEEDBACK ON POWER OF ADJACENT FREQUENCY BANDS

2012 ◽  
Vol 24 (04) ◽  
pp. 307-312 ◽  
Author(s):  
Majid Ghoshuni ◽  
Mohammad Firoozabadi ◽  
Mohammad Ali Khalilzadeh ◽  
Mohammad Reza Hashemi Golpayegani
Keyword(s):  
Cognitive Functions ◽  
Significant Positive Correlation ◽  
Healthy Individuals ◽  
Neurofeedback Training ◽  
Frequency Bands ◽  
Positive Correlation ◽  
Sensorimotor Rhythm ◽  
The Given

Sensorimotor rhythm (SMR) neurofeedback training (NFT) has an important role in improvement of cognitive functions in both clinical and healthy individuals. It is very possible that in SMR NFT adjacent frequency bands, such as alpha and beta1, be affected by SMR enhancing neurofeedback. Therefore, the adjacent frequency bands, in addition to SMR, may be associated with the improvement of the cognitive functions. Eight sessions of NFT were applied to healthy individuals to enhance their SMR activity. In order to investigate the effect of SMR enhancing neurofeedback on the power of adjacent frequency bands, correlation between the change in SMR activity and the change in alpha or beta1 activity was computed. The results revealed that there is a highly significant positive correlation between the change in SMR and beta1 activities. The given outcome suggests that during SMR NFT, the effect of both SMR and beta1 be considered together on the improvement of the cognitive functions.

Homeorhesis during early lactation. Euthyroid sick-like syndrome in lactating cows

1985 ◽  
Vol 110 (4) ◽  
pp. 505-509 ◽  
Author(s):  
C. Aceves ◽  
A. Ruiz-J. ◽  
C. Romero ◽  
C. Valverde-R.
Keyword(s):  
Environmental Temperature ◽  
Weather Conditions ◽  
Serum Levels ◽  
First Trimester ◽  
Early Lactation ◽  
Hormone Metabolism ◽  
Thyroid Hormone Metabolism ◽  
Clear Cut ◽  
Lactating Cows ◽  
Different Seasons

Abstract. Serum levels of thyroxine (T4), triiodothyronine (T3) and reverse T3 (rT3) were studied in dry, early (first trimester) and middle (second trimester) lactating purebred Holstein cows. The study encompassed three different seasons: autumn, winter and spring. Under comfortable weather conditions (temperature 22°C; relative humidity, 40%) or moderately hot (28°C; 60%), January and October, respectively, cows in early lactation exhibited significantly lower levels of T4 and T3, and higher values of rT3 than dry or middle lactating animals. In contrast, during May, when environmental temperature increased (34°C; 40%), a clear-cut shift in T3/rT3ratio occurred, and animals in early lactation exhibited the highest T3 and the lowest rT3 concentrations. These findings suggest that in dairy cattle, peripheral thyroid hormone metabolism plays a major role in regulating the homeorhetic responses involved in the maintenance of high priority functions.

SERUM LEVELS OF TSH, T3, rT3, T4 AND T3-RESIN UPTAKE IN SURGICAL TRAUMA

1978 ◽  
Vol 88 (3) ◽  
pp. 482-489 ◽  
Author(s):  
H.-O. Adami ◽  
H. Johansson ◽  
L. Thorén ◽  
L. Wide ◽  
G. Åkerström
Keyword(s):  
Reference Range ◽  
Binding Capacity ◽  
Serum Levels ◽  
Suppressive Effect ◽  
Surgical Trauma ◽  
Hormone Metabolism ◽  
Thyroid Hormone Metabolism ◽  
Endogenous Cortisol ◽  
Protein Binding Capacity

ABSTRACT Changes in thyroid hormone metabolism induced by surgical trauma were studied by determination of TSH, T3, rT3, T4 and T3-resin uptake before, during and after mastectomy in 20 women and cholecystectomy in 10 women. Pronounced and reciprocal changes, explained by altered peripheral T4 metabolism were found concerning T3 and rT3. The decreased T3 and increased rT3-levels approached or exceeded the limits of the reference range on the first post-operative day. A significant increase in T3-resin uptake and a decrease in serum T4 were already observed during surgery and probably was caused by a decreased protein binding capacity. An increased concentration of TSH in the serum during surgery was followed by a significant post-operative decrease, possibly due to a suppressive effect of endogenous cortisol. No obvious difference in absolute values or the pattern of change was found between the mastectomy and cholecystectomy groups, although a somewhat more pronounced and retarded alteration in rT3 was found after cholecystectomy.

scholarly journals Cord levels of zinc and copper in relation to maternal serum levels in different gestational ages

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
May Abdellatif ◽  
Ismail Mohamed Elhawary ◽  
Marwa Mohamed Mahmoud ◽  
Eman R. Youness ◽  
Walaa Alsharany Abuelhamd
Keyword(s):  
Gestational Age ◽  
Significant Positive Correlation ◽  
Serum Zinc ◽  
Serum Levels ◽  
Full Term ◽  
Anthropometric Measurements ◽  
Preterm Neonates ◽  
Published Data ◽  
Positive Correlation ◽  
The Mean

Abstract Background A few published data on maternal and cord levels of zinc and copper with conflicting results were reported. We aimed to measure zinc and copper levels in the maternal blood and cord blood of newborns and correlate their levels with the gestational age and anthropometric measurements. This cross-sectional study included 75 full-term and preterm neonates and their mothers. These neonates were divided into 2 groups according to their gestational age. Serum levels of copper and zinc were estimated for the mothers of the studied neonates as well as their cord samples. This was done using atomic absorption spectrophotometry. Results The mean cord serum zinc in full term was 0.88 ± 0.18 μg/ml whereas in preterms was 0.73 ± 0.13 μg/ml. The mean cord copper in full term was 1.37 ± 0.26 μg/ml, whereas in preterms was 0.75 ± 0.28 μg/ml. Comparison between cord zinc and copper levels and maternal levels were statistically significant (p < 0.001). A significant positive correlation was found between zinc levels in neonates and their mothers (r 0.644; p < 0.000) and a similar positive correlation was found between copper levels in neonates and their mothers (r 0.625; p 0.000). A highly significant positive correlation was found between cord zinc and copper and anthropometric measurements. Conclusion The present work draws our attention to the significant correlation between trace elements in pregnant mothers and fetal development. Also, prematurity adversely influences zinc and copper levels in neonates.

scholarly journals Melatonin May Be Associated With Left Ventricular Diastolic Dysfunction in Pediatric Patients With Heart Failure

2021 ◽  
Author(s):  
Yao Wu ◽  
Jian Qi Yi
Keyword(s):  
Heart Failure ◽  
Diastolic Dysfunction ◽  
Significant Positive Correlation ◽  
Pediatric Patients ◽  
Serum Levels ◽  
Significant Negative Correlation ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Positive Correlation ◽  
Ventricular Diastolic Dysfunction

Abstract BackgroundMelatonin has a protective role in adults with cardiovascular diseases. Diastolic dysfunction has been less well investigated in pediatric heart disease, and the effects of melatonin on cardiac diastolic dysfunction in children are not well understood. This study was designed to explore whether diastolic dysfunction is associated with the serum levels of melatonin or NO in children suffering from heart failure (HF) due to different etiology.Methodsforty-seven pediatric patients with HF were enrolled in this study. Echocardiographic parameters were employed to evaluate the cardiac diastolic dysfunction. Diurnal serum levels of melatonin and NO were measured and analyzed in all pediatric patients.ResultsDiurnal serum melatonin levels were positively correlated with mitral valve E:A ratio (E/A) in children with HF (P=0.044), especially in children with HF due to cardiomyopathy (P=0.023). Moreover, serum melatonin levels showed significant positive correlation with E/A ratio in children with deteriorate diastolic dysfunction when employing E/A < 1 or > 2 as an indicator (P=0.012), and especially in children with HF due to cardiomyopathy (P=0.0014). Serum melatonin levels demonstrated significant positive correlation with mitral regurgitation (MR) jet area (P =0.005) and showed significant negative correlation with pulmonary valve regurgitation (PVR) velocity (P =0.009). In addition, serum NO levels were positively correlated with isovolumetric relaxation time (IRT) in children with HF(P=0.0047). Furthermore, the optimal cutoff value of serum melatonin levels for diagnosis for predicting E/A＞2 in pediatric patients with HF was 84 pg/mL.ConclusionsDiurnal serum melatonin and NO levels may be associated with left ventricular diastolic dysfunction in pediatric HF especially due to cardiomyopathy.

scholarly journals The clinical significance of quantitative HBSAG in patients with HBEAG negative chronic hepatitis B

2019 ◽  
Vol 49 ◽  
Author(s):  
Marija Dimzova ◽  
Mile Bosilkovski ◽  
Magdalena Gasheva ◽  
Boban Toshevski ◽  
Biljana Petreska ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Clinical Significance ◽  
Significant Positive Correlation ◽  
Serum Levels ◽  
Hbv Dna ◽  
Positive Correlation ◽  
Negative Chronic Hepatitis

Background: The quantification of HBsAg provides different and complementary information that helps in determination of the different phases of chronic hepatitis B viral infection, evaluation and follow-up of liver disease progression as well as in treatment individualization.Aim: To evaluate the clinical significance of quantitative HBsAg (qHBsAg) in patients with HBeAg negative chronic hepatitis (CHB) and its correlation with the serum levels of alanine aminotransferase (ALT), quantitative HBV DNA and liver fibrosis.Subjects and Methods: The study included 53 treatment naïve patients with HBeAg negative chronic hepatitis B. All patients underwent complete laboratory and serology testing, quantification of HBV DNA and HBs antigen. The liver stiffness was measured with elastography. Patients’ demographic characteristics, viral and biochemical markers were recorded at one point of time.Results: Correlation analysis between the qHBsAg and ALT showed an significant, positive correlation between the parameters for R=0.42 and p<0.05; there was statistically non-significant positive correlation for R=0.25 and p>0.05 between qHBsAg and HBV DNA. There was a positive correlation between qHBsAg and liver fibrosis for R=0.08 and p>0.05. The serum levels of HBsAg had greater impact on the serum levels of ALT compared to that of HBV DNA for R=0.15 and p>0.05.Conclusion: Patients with higher ALT values and higher liver fibrosis score have higher qHBsAg; qHBsAg can reflect the serum HBV DNA levels.

scholarly journals Autumn and winter kidney fat indexes of roe deer does and their correlation with reproductive parameters

2013 ◽  
pp. 61-65
Author(s):  
István Majzinger
Keyword(s):  
Significant Positive Correlation ◽  
Roe Deer ◽  
Recruitment Rate ◽  
Corpora Lutea ◽  
Strong Positive Correlation ◽  
Reproductive Parameters ◽  
Game Management ◽  
Positive Correlation ◽  
Kidney Fat ◽  
Autumn And Winter

I studied the variations of kidney fat indexes (KFI) in two game management units of the Great Hungarian Plain between 2002 and 2004 in the autumn and winter months. I was looking for correlation between the autumn and winter KFI as well as between the autumn KFI and reproductive parameters (number of corpora lutea, recruitment rate). There was a significant positive correlation between the average winter and the average next autumn KFI (r=0.991, p<0.1). The average winter KFI showed strong positive correlation with the average number of corpora lutea (CL) in the next rutting season (r=0.978, p<0.05). The average autumn KFI and the average grown up offspring showed positive but not significant correlation (r=0.725, p=0.275).

scholarly journals Oxidative stress in myocardial infarction-does it correlate with the cardiac marker troponin?

2021 ◽  
Vol 8 (3) ◽  
pp. 190-192
Author(s):  
Pallavi R ◽  
Prabha S P ◽  
Sumina Cherian ◽  
Venugopal K ◽  
Geetha A
Keyword(s):  
Oxidative Stress ◽  
Myocardial Infarction ◽  
Heart Attack ◽  
Significant Positive Correlation ◽  
Troponin I ◽  
Healthy Controls ◽  
Healthy Individuals ◽  
Cardiac Marker ◽  
Positive Correlation ◽  
Significant Difference

A myocardial infarction (MI), often known as a heart attack, occurs when blood supply to a region of the heart is reduced or stopped, resulting in heart muscle damage. One of the elemental mechanisms responsible for the development of myocardial infarction is oxidative stress. The study aims to assess the Oxidative stress and Troponin I levels in patients with myocardial infarction (MI) and compare them with the level of these parameters in healthy controls. An attempt has been made to find if there is any correlation between oxidative stress and Troponin I levels in patients with myocardial infarction.The Cardiac marker Troponin I and the marker of oxidative stress malondialdehyde were estimated in 30 patients with myocardial infarction and 30 healthy individuals who acted as controls. A statistically significant difference was observed between Troponin I and MDA in patients with MI as compared with controls. A significant positive correlation was also observed between MDA and Troponin I levels. In our study there wasa significant positive correlation between oxidative stress and Troponin I. Further studies with a larger number of subjects will be needed to find if oxidative stress plays a role in the pathogenesis of myocardial infarction.

scholarly journals Growth differentiation factor 15: an emerging diagnostic biomarker of liver fibrosis in chronic hepatitis C patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Heba M. Adel Abou Zaghla ◽  
Aziza Ahmed El Sebai ◽  
Ossama Ashraf Ahmed ◽  
Ayat Fawzy Ahmed ◽  
Azza Abdel Rahman Saab
Keyword(s):  
Hepatitis C ◽  
Liver Fibrosis ◽  
Early Detection ◽  
Significant Positive Correlation ◽  
Serum Levels ◽  
Health Concern ◽  
Growth Differentiation Factor 15 ◽  
Positive Correlation ◽  
Differentiation Factor ◽  
Chronic Hcv

Abstract Background Chronic liver disease and cirrhosis are of the major health concern worldwide. Assessment of liver fibrosis is necessary to determine disease severity and prognosis at the time of presentation to determine suitable treatment. Liver biopsy is considered as standard golden method in diagnosis of liver fibrosis. However, this procedure is invasive; thus, multiple laboratory and radiologic tests are used to help determination of the degree of fibrosis. Growth differentiation factor 15 (GDF-15) is a pleiotropic cytokine involved in regulating inflammatory and apoptotic pathways. It is suggested that GDF-15 plays an important role in pathogenesis of liver fibrosis. In this study, we aimed to evaluate efficiency of growth differentiation factor 15 in diagnosing liver fibrosis. The study was a case-control study conducted on 55 chronic HCV patients recruited from hepatitis C virus clinic at Faculty of Medicine Ain Shams Research Institute (MASRI), and 30 healthy subjects age- and sex-matched. The patients were classified into three subgroups according to the degree of liver fibrosis assessed by fibro-scan. Serum concentration of GDF-15 was determined by enzyme-linked immunosorbent assay. Results Our results revealed a highly significant statistical rise in GDF-15 levels among studied chronic HCV patients with liver fibrosis when compared to the control group (p < 0.01). Furthermore, there was a significant positive correlation between the degree of fibrosis assessed by fibro-scan and GDF-15 serum levels. Levels of GDF-15 were significantly higher in patients with mild degree of fibrosis (patients’ subgroup І) when compared with the controls’ group (p < 0.01) suggesting the role of this marker in early detection of liver fibrosis. A statistically significant increase in serum GDF-15 levels was noticed among patients with advanced fibrosis “subgroup ІІІ” compared to those with mild fibrosis “subgroup І” (p < 0.05). The diagnostic sensitivity and specificity of GDF-15 were 96.7%, 98.2%, respectively at a cut-off value of 150 ng/L for discrimination between patients’ and controls’ groups. Conclusion Growth differentiation factor 15 could be a potential marker of liver fibrosis especially in early detection as its levels were significantly higher in patients’ group with liver fibrosis than controls’ group and there was a significant positive correlation between the degree of liver fibrosis and GDF-15 serum levels.

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