scholarly journals Seroprevalence and Associated Risk Factors of Infectious Bronchitis Virus in Chicken in Northwest Ethiopia

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
M. Birhan ◽  
M. Temesgen ◽  
A. Shite ◽  
N. Berhane ◽  
M. Bitew ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Infectious Bronchitis Virus ◽  
Northwest Ethiopia ◽  
Economic Losses ◽  
Mixed Effect ◽  
Infectious Bronchitis ◽  
Farm Type ◽  
Significant Difference ◽  
Potential Risk Factors

Avian infectious bronchitis virus is a highly contagious disease occurring in respiratory, urogenital, and reproductive tissues of chicken causing considerable losses due to death, egg drop, and reduced production. This preliminary study was conducted to investigate the prevalence of antibodies against infectious bronchitis virus (IBV) and to assess the potential risk factors in chickens of northwest Ethiopia. A cross-sectional study was conducted from November 2020 to June 2021. A total of 768 serum samples from three zones were collected. To investigate the presence of antibodies against IBV, the indirect ELISA serological test was applied. Positivity for anti-IBV antibodies was observed in 23.96% (95% CI: 20.98–27.14) of the samples. The mixed-effect logistic regression analysis of potential risk factors showed that IBV prevalence was significantly higher in young chickens than adults ( p < 0.001 ) and higher in intensive farm type than in extensive type ( p < 0.001 ). Based on the production purposes of the chickens, the odds of seropositivity for IB was significantly higher in layers than in broilers ( p < 0.001 ) and dual purposes ( p < 0.001 ). This study revealed higher seroprevalence in farms which had the “all-in-all-out” rearing method than in farms with different batches in one house with a significant difference ( p < 0.001 ), higher seroprevalence in the poor ventilated type than in good ones ( p < 0.001 ), and higher seroprevalence in the houses that did not remove used litter at all than houses of completely disposed and partially disposed litter ( p = 0.002 ). Moreover, disinfection of houses had significant effect on the occurrence of IB. Having personal protective equipment was significantly affecting the occurrence of IB, being higher in the farms that have no wearing clothes and shoe than in those having wearing clothes and shoe ( p = 0.002 ). In conclusion, the seroprevalence finding in the present study indicated that the organism is circulating among the population of chickens and high enough to cause significant economic losses Therefore, poultry houses should be cleaned, disinfected, and well ventilated and farm attendants should have separate farm shoe and clothes. Further studies on the virus isolation and molecular characterization of the target gene are needed in the study area.

scholarly journals Correlation between Potential Risk Factors and Pulmonary Embolism in Sarcoidosis Patients Timely Treated

2021 ◽  
Vol 10 (11) ◽  
pp. 2462
Author(s):  
Barbara Ruaro ◽  
Paola Confalonieri ◽  
Mario Santagiuliana ◽  
Barbara Wade ◽  
Elisa Baratella ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Embolism ◽  
Potential Risk ◽  
Smoking Habit ◽  
Age At Diagnosis ◽  
Antiphospholipid Antibody ◽  
Increased Risk ◽  
Significant Difference ◽  
Antibody Positivity ◽  
Potential Risk Factors

Background. Some studies with inconclusive results have reported a link between sarcoidosis and an increased risk of pulmonary embolism (PE). This study aimed at assessing a possible correlation between potential risk factors and PE in sarcoidosis patients. Methods. A total of 256 sarcoidosis patients (84 males and 172 females; mean age at diagnosis 49 ± 13) were enrolled after giving written informed consent. Clinical evaluations, laboratory and radiology tests were performed to evaluate the presence of pulmonary embolism. Results. Fifteen sarcoidosis patients with PE (4 males and 11 females; mean age at diagnosis 50 ± 11), diagnosed by lung scintigraphy and 241 sarcoidosis patients without PE (80 males and 161 females; mean age at diagnosis 47 ± 13), were observed. There was a statistically significant increase of the presence of antiphospholipid antibodies in the sarcoidosis group with pulmonary embolism. There was no statistically significant difference between the two groups as to smoking habit, obesity or hereditary thrombophilia frequency (p > 0.05, respectively). Conclusions. This study demonstrates a significant correlation between the presence of antiphospholipid antibody positivity and the pulmonary embolism events in our sarcoidosis patients. Furthermore, we propose screening for these antibodies and monitoring, aimed at timely treatment.

scholarly journals Sero-epidemiological survey of bluetongue disease in one-humped camel (Camelus dromedarius) in Kassala State, Eastern Sudan

2021 ◽  
Vol 74 (1) ◽  
Author(s):  
Molhima M. Elmahi ◽  
Mohammed O. Hussien ◽  
Abdel Rahim E. Karrar ◽  
Amira M. Elhassan ◽  
Abdel Rahim M. El Hussein
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Animal Health ◽  
Water Source ◽  
Economic Losses ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Cross Sectional ◽  
Potential Risk Factors ◽  
Eastern Sudan

Abstract Background Bluetongue (BT) is a vector-borne viral disease of ruminant and camelid species which is transmitted by Culicoides spp. The causative agent of BT is bluetongue virus (BTV) that belongs to genus Orbivirus of the family Reoviridae. The clinical disease is seen mainly in sheep but mostly sub-clinical infections of BT are seen in cattle, goats and camelids. The clinical reaction of camels to infection is usually not apparent. The disease is notifiable to the World Organization for Animal Health (OIE), causing great economic losses due to decreased trade and high mortality and morbidity rates associated with bluetongue outbreaks. The objective of this study was to investigate the seroprevalence of BTV in camels in Kassala State, Eastern Sudan and to identify the potential risk factors associated with the infection. A cross sectional study using a structured questionnaire survey was conducted during 2015–2016. A total of 210 serum samples were collected randomly from camels from 8 localities of Kassala State. The serum samples were screened for the presence of BTV specific immunoglobulin (IgG) antibodies using a competitive enzyme-linked immunosorbent assay (cELISA). Results Seropositivity to BTV IgG was detected in 165 of 210 camels’ sera accounting for a prevalence of 78.6%. Potential risk factors to BTV infection were associated with sex (OR = 0.061, p-value = 0.001) and seasonal river as water source for drinking (OR = 32.257, p-value = 0.0108). Conclusions Sex and seasonal river as water source for drinking were considered as potential risk factors for seropositivity to BTV in camels. The high prevalence of BTV in camels in Kassala State, Eastern Sudan, necessitates further epidemiological studies of BTV infection in camels and other ruminant species to better be able to control BT disease in this region.

scholarly journals Seroprevalence of infectious bursal disease and its potential risk factors in backyard chicken production of Waliso district, South Western Shoa Zone, Ethiopia

2021 ◽  
Vol 20 (1) ◽  
pp. 95-105
Author(s):  
Chala Bedasa ◽  
◽  
Ararsa Duguma ◽  
Asamenew Tesfaye ◽  
Tadele Tolosa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Animal Health ◽  
Infectious Bursal Disease ◽  
Flock Size ◽  
Serum Samples ◽  
Significant Difference ◽  
Bursal Disease ◽  
Potential Risk Factors ◽  
Backyard Chicken

A cross sectional study on infectious bursal disease was conducted in apparently healthy backyard chicken at Waliso district of Southwestern Shoa, central oromia, Ethiopia from from November, 2018 to October, 2019. A total of 282 chickens were randomly selected to estimate seroprevalence of IBD infection and to identify the likely potential risk factors for the disease. Serum samples collected and serological test conducted in laboratory at National Animal Health Diagnosis and Investigation Center Sebeta, Ethopia. Out of 282 serum samples tested 224 were positive for indirect ELISA technique and the overall seroprevalence of IBDV in the study area was found to be 79.43% at individual level. Educational level of owners, kebeles and flock size significantly affect seroprevalence of IBD in the study area. The effect of difference in managements like source of replacement, frequency of house cleaning, use of disinfectant and isolation practice has a significant effect on IBDV sero-prevalence. A lower seroprevalence of IBDV was reported in good hygienic level of house (26.7%) than poor level of chicken house hygiene (96.4%) with statistically significant difference (P < 0.05). The seroprevalence of IBDV in the present study associated with chicken management, flock size, owner education level and other animal related risk factors for occurrence of the disease. Therefore, awareness on chicken health management, and importance of immunization would help to minimize the prevalence of the disease and play crucial role in the control of the disease. Furthermore, characterizing virus strains circulating in the area in future study is recommended.

Risk factors for gastrointestinal perforations in patients with metastatic colorectal cancer receiving bevacizumab plus chemotherapy

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 3535-3535 ◽  
Author(s):  
M. Sugrue ◽  
M. Kozloff ◽  
J. Hainsworth ◽  
S. Badarinath ◽  
A. Cohn ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Metastatic Colorectal Cancer ◽  
Potential Risk ◽  
Primary Tumor ◽  
Phase Iii ◽  
Community Based ◽  
Large Community ◽  
Significant Difference ◽  
Potential Risk Factors

3535 Background: Bevacizumab (BV) prolongs overall survival and progression-free survival when added to standard chemotherapy in patients (pts) with metastatic colorectal cancer (mCRC). BRiTE is a large, community-based observational registry of pts with mCRC receiving BV plus first-line chemotherapy (CT). Incidence rate, temporal pattern, and potential risk factors associated with gastrointestinal perforation (GIP) were explored. Methods: Baseline patient characteristics (BC), including prospectively identified potential risk factors for GIP, were collected at study entry. Safety data were collected every 3 months (mo). Logistic regression models, adjusted and unadjusted for treatment assignment, were used to identify BC potentially associated with GIP. Results: 1968 pts were enrolled between Feb 2004 and Jun 2005. Median study follow-up was 10 mo as of Nov 4, 2005. GIPs were observed in 34 pts (1.7%). For pts with GIP, median time to first event was 2.1 mo; the majority of events were non-fatal and occurred within the first 3 mo after starting BV. BC including GI medical history (chronic aspirin or NSAID use, peptic ulcer disease, diverticulosis) were similar in pts with or without GIP and with earlier or later GIP onset (≤ or >3 mo from start of BV). Although adjusted models did not show any significant BC, GIP rates were numerically higher in pts with primary tumor intact (2.6%) vs. resected (1.6%). Furthermore, univariate analyses revealed a significant difference between intact (2.3%) and resected (0.8%) primary tumor for earlier GIP (≤3 mo from start of BV). The majority of pts with GIP had at least one of the following: acute diverticulitis, intra-abdominal abscess, gastrointestinal obstruction, tumor at GIP site, abdominal carcinomatosis, prior abdominal or pelvic radiation therapy. Conclusions: Preliminary analyses indicate the incidence of GIP in this large, community-based observational registry is similar to that previously reported in phase III mCRC trials with BV. No associations between specific BCs and an increased risk of GIP were identified. Patients with primary tumor intact were more likely to incur a GIP within the first 3 mo of starting BV and CT. [Table: see text]

scholarly journals Prevalence of and risk factors for feline hyperthyroidism in Hong Kong

2009 ◽  
Vol 11 (4) ◽  
pp. 315-321 ◽  
Author(s):  
Cornelia S. De Wet ◽  
Carmel T. Mooney ◽  
Peter N. Thompson ◽  
Johan P. Schoeman
Keyword(s):  
Risk Factors ◽  
Hong Kong ◽  
Potential Risk ◽  
The Other ◽  
Food Type ◽  
Significant Difference ◽  
The World ◽  
Total Thyroxine ◽  
Potential Risk Factors ◽  
Specific Association

A study was conducted to determine the prevalence of and potential risk factors for feline hyperthyroidism in Hong Kong. Serum total thyroxine (T4) was measured in 305 cats aged 10 years and older that presented at various veterinary clinics in Hong Kong. The prevalence of hyperthyroidism (T4>50 nmol/l) within this population was 3.93% and there was no significant difference in prevalence between healthy (3.16%) and sick (4.37%) cats. Older cats (>15 years) were more likely to be affected and domestic shorthair cats were less likely to be diagnosed with hyperthyroidism than the other breeds combined. No specific association between the development of feline hyperthyroidism and food type was observed. The prevalence of feline hyperthyroidism in Hong Kong was less than that reported for most other parts of the world, despite the presence of previously identified risk factors.

scholarly journals Incidence of Calf Morbidity and Its Predictors in North Shewa, Amhara, Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Rahma Mohammed ◽  
Hailemariam Kefyalew ◽  
Dawit Kassaye
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Linear Models ◽  
Livestock Production ◽  
Economic Losses ◽  
Chi Square ◽  
Exact Test ◽  
Mixed Crop ◽  
The Face ◽  
Potential Risk Factors

Calf morbidity is an important productivity factor that results in huge economic losses in the success of livestock production in Ethiopia. However, there is no robust information on its rate and its predictors in the mixed crop livestock production system as most studies are targeted to intensive dairy farms. A longitudinal study design was conducted from December 2018 to April 2019 in Siyadeber and Wayu districts of Amhara region, Ethiopia. A total of 135 apparently healthy calves were enrolled from randomly selected fifty-fifty households in three Kebeles of the district, namely, Gash-amba, Siyadeber, and Wale-deneba. A pretested structured questionnaire was used to collect data about the potential risk factors upon the face-to-face interview made with the owners. Calves were monitored for the incidence of morbidity in a weekly visit basis, and any clinical abnormalities were recorded on registries. The chi-square and Fisher’s exact test followed by Generalized Linear Models for binomial family extensions for risk estimate were run, and a p value <0.05 was considered statistically significant. In this study, the overall incidence rate of calf morbidity among under six months of age was 388 calves per 100,000 days of follow-up, with a cumulative incidence of 34.1% (95% CI: 26.1–42.7). Calf diarrhea, pneumonia, septicemia, dehydration, and navel ill were the encountered health problems consecutively. Among the potential risk factors, calves from Siyadeber Kebele (RR = 2.11, 95% CI: 1.13–3.94), calves housed with other livestock (RR = 2.05, 95% CI: 1.10–3.80), housed with their dam (RR = 1.92, 95% CI: 1.20–3.05), without bedding (RR = 1.89, 95% CI: 1.20–2.94), and calves whose dam age ranges from 5 to 8 years (RR = 1.87, 95% CI: 1.05–3.35) were found to be predictors of calf morbidity. In general, the high calf morbidity rates established in this study together with the alarming predictors of calf morbidity entail attention by the concerning bodies on proper management and improved health care so as to reduce the calf morbidity.

The Crossroads of Posttraumatic Stress Disorder and Physician Burnout: A National Review of United States Trauma and Nontrauma Surgeons

2019 ◽  
Vol 85 (2) ◽  
pp. 127-135 ◽  
Author(s):  
Theresa N. Jackson ◽  
Jake P. Morgan ◽  
Diane L. Jackson ◽  
Taylor R. Cook ◽  
Kevin McLean ◽  
...  
Keyword(s):  
Risk Factors ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Potential Risk ◽  
Stress Disorder ◽  
Physician Burnout ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Significant Difference ◽  
Potential Risk Factors

Posttraumatic stress disorder (PTSD) among trauma surgeons is three times that of the general population, and physician burnout (PBO) among surgeons is rising. Given that PTSD and PBO are both stress-based syndromes, we aim to identify the prevalence and risk factors for PTSD among trauma and nontrauma surgeons, and determine if a relationship exists. A cross-sectional survey of surgeons was conducted between September 2016 and May 2017. Respondents were screened for PTSD and PBO. Traumatic stressors were identified, and 20 potential risk factors were assessed. The respondents (n = 1026) were grouped into trauma (n = 350) and nontrauma (n = 676). Between the cohorts, there was no significant difference in prevalence of screening positive for PTSD (17% vs 15%) or PBO (30% vs 25%). A relationship was found between PTSD and PBO (P < 0.001). The most common traumatic stressor was overwhelming work responsibilities. Potential risk factors for PTSD differed, but overlapping risk factors included hospital culture, hospital support, and salary (P < 0.05). Our findings of an association between PTSD and PBO is concerning. Interventions to reduce rates of PTSD should target changing the existing culture of surgery, improving hospital support, and ensuring equitable pay.

scholarly journals Haemodynamic analysis of adult patients with moyamoya disease: CT perfusion and DSA gradings

2020 ◽  
pp. svn-2019-000317
Author(s):  
Zhiyong Shi ◽  
Guofeng Ma ◽  
Dong Zhang
Keyword(s):  
Risk Factors ◽  
Basal Ganglia ◽  
Frontal Lobe ◽  
Potential Risk ◽  
Parietal Lobe ◽  
Ct Perfusion ◽  
Adult Patients ◽  
Arterial Stenosis ◽  
Significant Difference ◽  
Potential Risk Factors

ObjectMoyamoya disease (MMD) is a common and chronic progressive stenotic-occlusive cerebrovascular disease in Eastern Asia. To evaluate the hemispheric haemodynamic status of adult patients with MMD, we explored the potential risk factors of hemispheric perfusion alterations with CT perfusion (CTP) and DSA.MethodsWe retrospectively reviewed 44 male and 44 female (176 hemispheres) adult patients with MMD who had both DSA and CTP. Data on cerebral blood perfusion (CBF), cerebral blood volume (CBV), mean transmit time (MTT), time to peak (TTP) of cerebral hemisphere and cerebellum were gathered and difference of relative haemodynamic parameters between different subgroups were assessed with independent sample t analysis, one-way analysis of variance and general linear regression analysis.ResultsParameters in regional CBF (rCBF) of frontal, temporal lobe and basal ganglia in female was more superior than male. rCBF, regional MTT (rMTT) and regional TTP (rTTP) in adult MMD patients with haemorrhage were superior than the ischaemic. With the increase of age, significant difference could be seen in rCBF and rCBV of thalamus. However, with progress of arterial stenosis, significant difference could only be obsevrved in rCBV, rMTT and rTTP, whereas rCBF had no significant difference. For increase of moyamoya vessels, significant decrease of rCBF could be seen in temporal and parietal lobe. With the increase of compensatory artery numbers, no significant difference could be seen in rCBF parameters (p>0.05).ConclusionsIn adult MMD patients, age, gender and clinical type were potential risk factors for the change of cerebral perfusion. When arterial stenosis is worsened, moyamoya vessels could alter perfusion of temporal and parietal lobe, but not frontal lobe. Extracranial/intracranial compensatory arteries could maintain microcirculation stability in frontal lobe and basal ganglia, indicating that the protection from extracranial compensatory arteries, a theoretic base for surgery treatment if necessary.

scholarly journals Investigation of Risk Factors and Biosecurity Measures Associated with Prevalence of Newcastle Disease Virus in Broiler Farms

2020 ◽  
Vol 8 (11) ◽  
pp. 2426-2432
Author(s):  
Mirza Mienur Meher ◽  
Jaisan Islam ◽  
Marya Afrin
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Newcastle Disease ◽  
Significant Contribution ◽  
Management Practices ◽  
Farm Management ◽  
Economic Losses ◽  
Potential Risk Factors ◽  
Broiler Farm ◽  
Poultry Farming

Newcastle disease (ND) is one of the major viral diseases of poultry, remains a constant threat in poultry farms that causes huge economic losses every year. However, little is known regarding the potential risk factors of the disease in broiler. The study was undertaken to ascertain the potential risk factors and biosecurity measures in ND prevalent broiler farm. A total of 116 broiler farms were considered as a sample size from a different area of Barishal district of Bangladesh in which 19.83% ND prevalence was found. In the findings, the farmers (33.62%) who had training on poultry farming, were significantly less ND positive case (7.69%). Besides this, among the different risk factors and biosecurity measures only shed location, ventilation, vaccination status, feeder and waterer cleaning frequency, visitors accession, pets in the farm, use of disinfectant and seasonal variation had significant effect on ND outbreak. However, among all the factors only farmers training (OR=0.025; 95% CI: 0.001-0.509), shed location (OR=0.035; 95% CI: 0.003-0.390), vaccination against ND (OR=0.017; 95% CI: 0.001-0.435) and use of disinfectant daily (OR=0.011; 95% CI: 0.000-0.294) made a unique statistically significant contribution to the regression model and the predictors had approximately similar strength on reporting ND outbreak. In completion, ND can be reduced in broiler farms by improving the level of common biosecurity, farm management practices, and minimizing the potential risk factors through training of farmers, awareness build-up, and enforcement of these practices on the farms.

scholarly journals Immunosuppressive Properties of Infectious Bronchitis Vaccine4/91 strain against different programs and method of vaccination against Newcastle disease in Broilers

2012 ◽  
Vol 11 (3) ◽  
pp. 13
Author(s):  
A.H. Zahid
Keyword(s):  
Respiratory Disease ◽  
Infectious Bronchitis Virus ◽  
Newcastle Disease ◽  
Haemagglutination Inhibition ◽  
Challenge Test ◽  
Economic Losses ◽  
Control Group ◽  
Infectious Bronchitis ◽  
Spray Method ◽  
Significant Difference

Infectious bronchitis virus (IBV) primarily induces a respiratory disease in broilerscausing important economic losses in poultry industry. The aim of this study was to investigatethe immunosuppressive properties of live IB vaccine on the different programs and method ofvaccination against Newcastle disease (ND) in broilers. A total of 125 one-day-old broilerchicks were assigned into five equal groups. At day one G1 and G2groupswere vaccinated witha live (ND, IB)vaccine by dipping the head in the vaccine and intra-cloacae methodrespectively. Afterward, G3and G4 groups were vaccinated with a live ND vaccine alone by thesame method of G1 and G2. At the same time all these4 groups were vaccinated bysubcutaneous injection (S/C) with inactivated oil based vaccine ND. The G5 group was leftwithout vaccination as a control group. After that, all treated groups were vaccinated with a liveND by spray method at day 10 of the age. The immunosuppressive effects of this IB virus wasevaluated by Haemagglutination inhibition test (HI), and challenged by virulent ND virus.Bursa and Spleen indices were estimated in all groups. The results showed that the antibodytiters against ND was higher (P<0.05) in G3and G4 in compared with G1, G2 and controlgroups at 20 and 30 days of age. However, there was no significant difference of bursa indexand spleen index in all groups. Challenge test showed no mortality in the 3rd group while 10%in the 4th group, 85% in the 1st group and 90% in the 2nd group. In conclusion, it’s revealed thatthe best method and program of vaccination which can protect against ND was applied in the3rd group.

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