Technological Advancements in Monoclonal Antibodies

Biopharmaceuticals are innovative solutions that have revolutionized the treatment of important chronic diseases and malignancies. The approval of biosimilar products has become a complex and balanced process, and there are versions of drugs with established biosimilarity that can offer a more accessible treatment option to patients. The objective of this work was to identify the advancement of these technologies by means of patent and article analysis based on technological and scientific prospection. In patent document recovery, Derwent Innovation Index (DWPI) and PatentInspiration databases were used. The research was based on the search of the selected terms in the title, summary, and claims of the documents through a search strategy containing IPC code and keywords. In articles recovery, the Web of Science tool was used in the search of scientific publications dated from the last 5 years. The search resulted in a total of 2295 individual patent documents and 467 families using DWPI database, 769 individual patents and 205 families using PatentInspiration, and 2602 articles using Web of Science database. Additionally, this work describes the number of organizations that contribute to this area, where they are, how much development they have undergone, and the inventors/authors involved. Based on the number of publications registered, there is an important prominence for scientific research in mAbs. In terms of innovation, it is expected that several therapeutic drugs are already under regulatory review, which will allow drugs to be approved over the next few years and will thus generate a continuous flow of new products based on immunotherapies, mAbs, and biosimilar drugs. These drugs have become essential weapons for the treatment of significant diseases, and the increasing trend in the number of related scientific and technological publications contributes to making these therapies available to the greatest number of people.

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Some scientific publications of BPKIHS: a bibliometric study of articles listed in the Web of Science

Health Renaissance ◽

10.3126/hren.v10i2.6584 ◽

2012 ◽

Vol 10 (2) ◽

pp. 139-143

Author(s):

S Risal ◽

H N Prasad

Keyword(s):

Citation Analysis ◽

Bibliometric Analysis ◽

Scientific Community ◽

Web Of Science ◽

Scientific Productivity ◽

Health Sciences ◽

Academic Institution ◽

Scientific Publications ◽

Number Of Publications ◽

The Web

Scientific productivity of any academic institution is expressed by the total number of publications generated by its academic faculties and the use of the publication by scientific community. Citation analysis is done to evaluate the use of the publications. Use of the publication can be studied with the help of bibliometric analysis. Counting publication, publications trends, authorship patterns and citation analysis are parts of bibliometric analysis. Web of Science is one of the best databases which allow the study in the use of the publications through citation analysis. In this article, scientific articles produced by the faculties and other international affiliated faculties of BP Koirala Institute of Health Sciences have been studied. Citation analysis of scientific publications of BP Koirala Institute of Health Sciences is done with the help of the Web of Science, a product of Thomason Reuters.DOI: http://dx.doi.org/10.3126/hren.v10i2.6584 Health Renaissance 2012; Vol 10 (No.2); 139-143

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The Association Between Professional Accounts on Social Networks Twitter and ResearchGate and the Number of Scientific Publications and Citations Among Anesthesia Researchers: Observational Study (Preprint)

10.2196/preprints.29809 ◽

2021 ◽

Author(s):

Thomas Clavier ◽

Emilie Occhiali ◽

Zoé Demailly ◽

Vincent Compère ◽

Benoit Veber ◽

...

Keyword(s):

Social Networks ◽

Web Of Science ◽

Scientific Publication ◽

Scientific Publications ◽

H Index ◽

The Social ◽

Twitter Account ◽

Number Of Publications ◽

Number Of Citations ◽

Science Citation Index Expanded

BACKGROUND Social networks are now essential tools for promoting research and researchers. However, there is no study investigating the link between presence or not on professional social networks and scientific publication or citation for a given researcher. OBJECTIVE The objective of this study was to study the link between professional presence on social networks and scientific publications/citations among anesthesia researchers. METHODS We included all the French full professors and associate professors of anesthesia. We analyzed their presence on the social networks Twitter (professional account with ≥1 tweet over the 6 previous months) and ResearchGate. We extracted their bibliometric parameters for the 2016-2020 period via the Web of Science Core Collection (Clarivate Analytics) database in the Science Citation Index-Expanded index. RESULTS A total of 162 researchers were analyzed; 42 (25.9%) had an active Twitter account and 110 (67.9%) a ResearchGate account. There was no difference between associate professors and full professors regarding active presence on Twitter (8/23 [35%] vs. 34/139 [24.5%], respectively; P=.31) or ResearchGate (15/23 [65%] vs. 95/139 [68.3%], respectively; P=.81). Researchers with an active Twitter account (median [IQR]) had more scientific publications (45 [28-61] vs. 26 [12-41]; P<.001), a higher h-index (12 [8-16] vs. 8 [5-11]; P<.001), a higher number of citations per publication (12.54 [9.65-21.8] vs. 10.63 [5.67-16.10]; P=.01), and a higher number of citations (563 [321-896] vs. 263 [105-484]; P<.001). Researchers with a ResearchGate account (median [IQR]) had more scientific publications (33 [17-47] vs. 26 [9-43]; P=.03) and a higher h-index (9 [6-13] vs. 8 [3-11]; P=.03). There was no difference between researchers with a ResearchGate account and those without it concerning the number of citations per publication and overall number of citations. In multivariate analysis including sex, academic status, and presence on social networks, the presence on Twitter was associated with the number of publications (β=20.2; P<.001), the number of citations (β=494.5; P<.001), and the h-index (β=4.5; P<.001). CONCLUSIONS Among French anesthesia researchers, an active presence on Twitter is associated with higher scientific publication and citations.

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Published Research on Burnout in Nursing in Spain in the Last Decade: Bibliometric Analysis

Healthcare ◽

10.3390/healthcare8040478 ◽

2020 ◽

Vol 8 (4) ◽

pp. 478

Author(s):

Ana Belén Barragán Martín ◽

María del Mar Molero Jurado ◽

María del Carmen Pérez-Fuentes ◽

María del Mar Simón Márquez ◽

Maria Sisto ◽

...

Keyword(s):

Healthcare Professionals ◽

Web Of Science ◽

Publication Rate ◽

Scientific Production ◽

Intervention Programs ◽

Burnout Syndrome ◽

Scientific Publications ◽

The Subject ◽

Number Of Publications ◽

Published Research

Scientific production in the last decades has evidenced an increase in burnout syndrome in healthcare professionals. The objective of this bibliometric study was to analyze scientific productions on burnout in nurses in 2009–2019. A search was made on the Web of Science database on burnout in nursing. The variables evaluated were number of publications per year, productivity based on the journal and relationships between authors. Data were analyzed using Bibexcel software, and Pajek was used to visualize the co-authorship network map. A total of 1528 publications related to burnout in nurses were identified. The years with the most productivity were 2016 to 2017, when the publication rate increased noticeably over previous years. The Spanish journal with the most production on the subject was Atención Primaria. The co-authorship network analyzed illustrated collaboration patterns among the researchers. Scientific publications on the subject have increased in recent years due to problems in the healthcare system, which is in need of prevention and intervention programs for healthcare professionals.

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Country Differences and Changes in Focus of Scientific Tobacco Control Publications between 2000 and 2012 in Europe

European Addiction Research ◽

10.1159/000381674 ◽

2015 ◽

Vol 22 (1) ◽

pp. 52-58 ◽

Cited By ~ 6

Author(s):

Marc C. Willemsen ◽

Gera E. Nagelhout

Keyword(s):

Tobacco Control ◽

Web Of Science ◽

Research Output ◽

Scientific Publications ◽

Environmental Interventions ◽

Global Trends ◽

Control Research ◽

Country Differences ◽

Number Of Publications ◽

Smoking And Health

Background/Aims: The Framework Convention on Tobacco Control (FCTC) stresses the importance of scientific research. We examined the differences between 31 European countries regarding quantity and focus of tobacco control research publications. Methods: PubMed, Web of Science, Scopus, and PsycInfo were searched for peer-reviewed articles on tobacco, written by European authors, published between 2000 and 2012. For 2000, 2004, 2008, and 2012 we further identified the main focus of the publication. Results: The volume of European tobacco control scientific publications had almost doubled. Scandinavian countries had most publications per inhabitant, while Bulgaria, Cyprus, Estonia, Latvia, Lithuania, Malta, Romania, Slovakia, and Slovenia had relatively little research output. There was a smaller increase in publications about harm from tobacco, relative to publications about treatment, and education, and to publications about environmental interventions. In 2012, 49% of all publications were about health, while the total number of publications on environmental interventions was relatively small (10%). Conclusion: Research output had almost doubled, in line with global trends, but is still unevenly distributed across Europe. Although we observed a shift in European publications away from the harm of tobacco towards protecting smokers and changing the environment, the field is still dominated by publications on smoking and health.

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The Enterprise's Integrated Reporting: Bibliometric Analysis

Accounting and Finance ◽

10.33146/2307-9878-2021-3(93)-5-10 ◽

2021 ◽

pp. 5-10

Author(s):

Vasyl Hayk ◽

Keyword(s):

Bibliometric Analysis ◽

Information Disclosure ◽

Web Of Science ◽

Scientific Development ◽

Integrated Reporting ◽

Scientific Publications ◽

Scientific Schools ◽

Number Of Publications ◽

New Research ◽

Selection Of

The development of approaches to understanding integrated reporting and the identification of the scientific landscape in this area are becoming increasingly important, as the requirements and requests for information from stakeholders are constantly growing. The article contains a bibliometric content analysis of scientific publications on the topic of integrated reporting. The selection of information for bibliometric analysis was carried out in the two most authoritative scientometric databases Scopus and Web of Science on the keyword “integrated reporting” (integrated reporting) during the period 1990-2020. The study identified 308 and 393 publications in the Scopus and Web of Science databases, respectively. It was established that the databases from the total number of publications are dominated by articles 213 (69.2 %) and 300 (66.1 %), respectively. The interest among scientists on this topic is growing, as the number of publications has been increasing in recent years. Since 2014, there has been a sharp increase in published works on this topic. This is primarily due to the fact that in 2014, at the plenary session of the XIX World Congress of Accountants, the International Council on Integrated Reporting approved the gradual adoption of the International Framework for Integrated Reporting over the next three years, which sparked public debate. The using of VOSviewer software allowed to build and visualize bibliometric maps. The bibliometric maps made it possible to identify the most commonly used keywords (reporting, integrated report, information disclosure) and authors in the studied articles (W. Maroun, C. De Villiers, J. Dumay), which form individual scientific schools. This study reflects trends in integrated reporting and provides scientists with guidance for further scientific development. In particular, this study helps create a conceptual framework, provides a source for scientists to conduct new research by assessing gaps, and provides opportunities for comparison and analysis.

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Russia in the world array of scientific publications

Вестник Российской академии наук ◽

10.31857/s0869-5873898820-830 ◽

2019 ◽

Vol 89 (8) ◽

pp. 820-830

Author(s):

Yu. V. Mokhnacheva ◽

V. A. Tsvetkova

Keyword(s):

Web Of Science ◽

Soviet Period ◽

Global Flow ◽

Scientific Publications ◽

Subject Categories ◽

The World ◽

Number Of Publications ◽

World Ranking ◽

Ranking Position ◽

Post Soviet Period

This article presents the results of a study on the representation of Russian publications in the global array of publications that discuss narrow thematic areas within the entire post-Soviet period, using ranking distributions from the Web of Science Core Collection (WoS CC). For extraction and analysis, the classifiers provided by the WoS categories were used. Of the 252 subject categories in the WoS CC, the share of Russian publications for 2010–2017 was not less than 0.4% of the global flow in 132 scientific areas. Therefore, in the period 1993–2000, a gradual recovery was found of Russia’s lost position in the world ranking of countries by number of publications in the WoS CC. Currently, positive changes have been observed both for the entire array of Russian publications in particular in narrow scientific topics. The highest-ranking position for Russian publications fell in 1993–1999, and the greatest decline, when the share of Russian publications fell to their minimum values, was in 2011–2014. Data on the scientific areas in which Russia managed to stay in the top 10 leading countries during its recent history, according to share of publications in the global array, are presented. This list slightly expanded from 2010 to 2017, and today, it includes 39 areas in which Russia is in the top 10 countries, and it is among the five leading countries in eight areas of knowledge.

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Mapping the Literature on Financial Behavior: a Bibliometric Analysis Using the VOSviewer Program

WSEAS TRANSACTIONS ON BUSINESS AND ECONOMICS ◽

10.37394/23207.2022.19.22 ◽

2022 ◽

Vol 19 ◽

pp. 231-246

Author(s):

Maksym Dubyna ◽

Olha Popelo ◽

Nataliia Kholiavko ◽

Artur Zhavoronok ◽

Maiia Fedyshyn ◽

...

Keyword(s):

Bibliometric Analysis ◽

Financial Services ◽

Web Of Science ◽

Data Retrieval ◽

Financial Behavior ◽

Scientific Publications ◽

Economic Agents ◽

Current State ◽

Financial Behaviour ◽

Number Of Publications

Objective of the article is to study the current state of researches of financial behaviour. The article is conceptual and based on the use of the methodology of the bibliometric analysis. The analysis is based on the data retrieval functionalities of Scopus and Web of Science platforms. Is used the toolkit of the VOSviewer program, network visualization of keywords in scientific publications. Findings: The number of publications that directly study the nature and features of the financial behavior formation of various economic agents is insignificant, but is constantly growing. An important role in this process is played by digitalization processes of financial services, which have an important impact on the models transformation of both financial behavior of economic agents, and changes in the model of the financial services provision to customers by financial institutions.

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THE REPRESENTATION OF SCIENTIFIC PUBLICATIONS OF RAMS IN WEB OF SCIENCE: EVALUATION OF CURRENT INDICATORS AND PROSPECTS OF THEIR INCREASING

Annals of the Russian academy of medical sciences ◽

10.15690/vramn.v67i9.408 ◽

2012 ◽

Vol 67 (9) ◽

pp. 59-64 ◽

Cited By ~ 1

Author(s):

V. I. Starodubov ◽

S. L. Kuznetsov ◽

N. G. Kurakova ◽

L. A. Tsvetkova

Keyword(s):

Web Of Science ◽

Bibliometric Indicators ◽

Medical Sciences ◽

Short Term ◽

Scientific Publications ◽

The Past ◽

Global Science ◽

The World ◽

Presidential Decree ◽

Number Of Publications

The contribution scientific publications of Russian Academy of Medical Sciences (RAMS) in the national publication stream, indexed by Web of Science over the past thirty years, was estimated. The indicators of publication activity that are necessary for the institutions of RAMS to achieve in short-term period the conformity with bibliometric indicators, established by Presidential Decree of May 7, 2012 (to increase the share of Russian publications in Web of Science to 2.44% in 2015) were calculated. It is shown that the current structure of global science, where publications in medicine make up for approximately one third of scientific publications in the world, set for RAMS scientists particularly difficult task: to double in three years the number of publications in Web of Sci. In the article are proposed the priorities and the necessary steps to fulfill this task.

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APPLICATION OF DEEP LEARNING

International Journal Vallis Aurea ◽

10.2507/ijva.7.1.3.78 ◽

2021 ◽

Vol 7 (1) ◽

pp. 39-51

Author(s):

Kristian Đokić ◽

◽

Hrvoje Mikolčević ◽

Ivica Šnajder ◽

◽

...

Keyword(s):

Machine Learning ◽

Deep Learning ◽

Web Of Science ◽

Scientific Publications ◽

The Third ◽

Cooperation Rate ◽

Number Of Publications ◽

Citation Databases ◽

The Web ◽

Number Of Authors

In the last decade, there has been a significant increase in the number of papers related to machine learning and the application of machine learning in various fields of science. Belmonte et al. observed that between 2010 and 2018, the growth in the number of papers related to machine learning topics and big data was exponential. They analysed 4240 scientific publications from the Web of Science citation database [1]. Xu et al., in the analysis of publications in the International Journal of Machine Learning and Cybernetics, noted that from 2010 to 2017, the number of publications, the cooperation rate, the total number of authors, and the degree of cooperation had shown an increasing trend [2]. Dokic et al. analysed the publication of papers in which deep learning is applied in the field of agriculture and noticed that the first papers were published in 2014, and in the second half of the second decade of the 21st century, exponential growth in the number of published papers was observed [3]. The objectives of this paper are primarily to analyze the literature related to the application of deep learning in apple growing, to propose the division of these papers depending on the area, and to analyze the observed trends in publishing papers related to this topic. In the analysis, only papers published in scientific journals were considered, and the condition is that they be found in the citation databases of the Web of Science or Scopus. The second section gives a brief overview of deep learning and its development and a presentation of the importance of apple growing in agriculture. The third section is an overview of papers that use deep learning methods and solve some problems in growing apples. The third section is divided into four parts, depending on the area the paper deals with. The fourth section is a discussion and conclusion.

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ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OF ACETYLSALICYLIC ACID: PHYSIOLOGICAL MECHANISMS

Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry ◽

10.37279/2413-1725-2020-6-1-197-219 ◽

2020 ◽

Vol 6(72) (1) ◽

pp. 197-219

Author(s):

I. V. Cheretaev ◽

D. R. Khusainov ◽

E. N. Chuyan ◽

M. Yu. Ravaeva ◽

A. N. Gusev ◽

...

Keyword(s):

Acetylsalicylic Acid ◽

Physiological Mechanism ◽

The Body ◽

Physiological Mechanisms ◽

Scientific Publications ◽

Thermal Pain ◽

Order Of Magnitude ◽

Anti Inflammatory ◽

Number Of Publications ◽

Electrical Stimuli

The purpose of the review is to summarize current literature data and the results of our own research on the analgesic and anti-inflammatory effects of acetylsalicylic acid, as well as the physiological mechanisms underlying them. This acid is the most studied reference representative of salicylates, which is convenient to consider the physiological effects characteristic in general for this group of chemical and medicinal products. Acetylsalicylic acid has analgesic properties against thermal pain and pain caused by electrical stimuli, as well as a pronounced anti-inflammatory effect. The realization of these properties depends on the peculiarities of aspirin metabolism in the body, ion and synaptic mechanisms for controlling the functional state of the cell, neurotransmitter systems of the сentral nervous system, and mechanisms of peripheral and сentral analgesia. Analgesic properties of acetylsalicylic acid founded not only in normal, but also in ultra-small doses. Various physical and especially chemical factors significantly change their effects. This increases the interest in studying the analgesic activity of salicylates and their physiological mechanisms, since such studies can serve as a basis for creating new non-steroidal anti-inflammatory drugs with low toxicity and high safety for patients, and improve the strategy of their practical use. Currently, the most detailed study of the physiological mechanism of analgesic and anti-inflammatory action of aspirin and its main metabolite – salicylic acid. However, it should be note that despite the abundance of existing data obtained in scientific studies of the effects of aspirin and its practical use, there are a number of unexplained aspects of the action of this drug, the mechanism of which has not yet been deciphered. The continuing interest in the effects and mechanisms of action of this drug and in connection with the expansion of its use evidenced by a consistently high number of scientific publications on aspirin in the most famous foreign and domestic publications. At the same time, the number of publications about aspirin is an order of magnitude higher than about any other drug known to humanity.

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