scholarly journals Oxidative Stress Risk Is Increased with a Sedentary Lifestyle during Aging in Mexican Women

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Martha A. Sánchez-Rodríguez ◽  
Mariano Zacarías-Flores ◽  
Elsa Correa-Muñoz ◽  
Alicia Arronte-Rosales ◽  
Víctor Manuel Mendoza-Núñez
Keyword(s):  
Oxidative Stress ◽  
Physical Activity ◽  
Aging Process ◽  
Sedentary Lifestyle ◽  
Principal Component ◽  
Poisson Model ◽  
Community Dwelling ◽  
Mexican Women ◽  
The Difference

Oxidative stress (OS) increases during the human aging process, and the sedentary lifestyle could be a prooxidant factor. In this study, we determine the effect of sedentary lifestyle on OS during the aging process in Mexican women. A longitudinal study of two-year follow-up was carried out with 177 community-dwelling women (40-69 y) from Mexico City. We measured as OS markers plasma malondialdehyde, erythrocyte glutathione peroxidase (GPx) and superoxide dismutase (SOD), total plasma antioxidant status, uric acid level, antioxidant gap, and SOD/GPx ratio. To define OS using all the markers, we defined cut-off values of each parameter based on the 90th percentile of young healthy subjects and, we calculated a stress score (SS) ranging from 0 to 7, which represented the intensity of the marker modifications. All the women answered a structured questionnaire about prooxidant factors, including physical activity specially the type of activity, frequency, and duration, and they answered Spanish versions of self-assessment tests for establishing dysthymia and insomnia as potential confounders. Principal component and Poisson regression analysis were used as statistical tools, being two-year OS the primary outcome. The OS was considerate as SS ≥ 4 and sedentary lifestyle as <30 min/day of physical activity, beside several prooxidant factors and age that were covariables. SS is higher in sedentary lifestyle women after the two-year follow-up; although, the difference was statistically significant only in older women. Four principal components were associated with the OS, and 7 out of 8 prooxidant factors were important for the analysis, which were included in the Poisson model. The predictive factors for OS were the sedentary lifestyle (adjusted PR = 2.37, CI95%: 1.30–4.30, p < 0.01 ), and age, in which the risk increases 1.06 (CI95%:1.02–2.11, p < 0.01 ) by each year of age. Our findings suggest that a sedentary lifestyle increases the OS during the aging in Mexican women.

scholarly journals Body Composition in Community-Dwelling Older Adults Before and After SARS-CoV-2 Infection: A Longitudinal Prospective Study in a Rural Village Struck by the Pandemic

2021 ◽  
Vol 12 ◽  
pp. 215013272110477
Author(s):  
Oscar H. Del Brutto ◽  
Robertino M. Mera ◽  
Denisse A. Rumbea ◽  
Pedro Pérez ◽  
Bettsy Y. Recalde ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Body Composition ◽  
Regression Models ◽  
Community Dwelling ◽  
The Body ◽  
Study Results ◽  
The Impact ◽  
Community Dwelling Older Adults

Background: Information on the body composition of inhabitants of remote communities during the SARS-CoV-2 pandemic is limited. Using a longitudinal population-based study design, we assessed the association between SARS-CoV-2 infection and changes in body composition. Methods: Community-dwelling older adults living in a rural Ecuadorian village received body composition determinations before and 1 year after the pandemic as well as serological tests for detection of SARS-CoV-2 antibodies. The independent association between SARS-CoV-2 infection and abnormalities in body composition at follow-up was assessed by fitting linear mixed models for longitudinal data. Results: Of 327 enrolled individuals, 277 (85%) received baseline and follow-up body composition determinations, and 175 (63%) of them became SARS-CoV-2 seropositive. Overall, diet and physical activity deteriorated during the follow-up. Multivariate random-effects generalized least squares regression models that included the impact of time and seropositivity on follow-up body composition, showed that neither variable contributed to a worsening in body composition. Multivariate logistic regression models disclosed that the serological status at follow-up cannot be predicted by differences in body composition and other baseline covariates. Conclusions: Study results suggest no increased susceptibility to SARS-CoV-2 infection among older adults with abnormal body composition and no significant changes as a result of worse physical activity and dietary habits or seropositivity during the length of the study. Together with a previous study in the same population that showed decrease in hand-grip strength after SARS-CoV-2, results confirm that dynapenia (and not sarcopenia) is associated with SARS-CoV-2 infection in older adults.

Abstract P199: Keep Moving, Your Health Depends On It: Impact Of Improved Physical Activity And Weight Loss In A Wellness Program

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Ebenezer T Oni ◽  
Ehimen Aneni ◽  
Maribeth Rouseff ◽  
Thinh Tran ◽  
Henry Guzman ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Weight Loss ◽  
Intervention Program ◽  
South Florida ◽  
Metabolic Equivalents ◽  
Baseline Weight ◽  
The Mean ◽  
The Difference

Negative impact of CVD as the leading cause of death in the US is worsened by the significant burden of obesity and associated morbidity and concerns about the growing population inactivity. The American Heart Association has emphasized worksite-based interventions to improve CV health. We evaluated the benefits of improved physical activity(PA) and weight loss(WL) among employees of the Baptist Health South Florida enrolled in a wellness intervention program. Methods: Employees with two or more Cardio-metabolic risk factors , such as total cholesterol ≥ 200 mg/dl, systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg, hemoglobin A1C ≥ 6.5%, and body mass index (BMI) ≥ 30 were enrolled in an intervention program themed “My unlimited potential”. Interventions were focused on diet and PA modifications. We defined improved physical activity as the difference in the metabolic equivalents (METs) at 12 weeks follow-up and at baseline. WL (lbs) was the difference in weight at follow-up. The relationship between WL and changes in METs was explored in an ordered logistic regression. Results: Overall 203 (48±10 years, 78% females) employees were enrolled with a retention rate of 89% (n=181) at 12 weeks follow-up. At baseline the median weights was 211 lbs., and mean METs- 8.6, while at follow-up the median weight was 200 lbs, and the mean METs 11. At 12 weeks follow up 38% had significant WL (lost >5% of baseline weight). The median WL was 8.4 (IQR 4.8-13.0) lbs and the mean change in METs was 2.4±1.8. Median WL increased with increasing tertiles of METs change; tertile1- 6.5(4-11) lbs., tertile2- 9(6-13)lbs. tertile3- 11(7-15)lbs. Increased PA was related to increased WL across BMI categories adjusting for age, gender and baseline weight. Conclusion: This study points strongly toward the benefit of increasing PA among other lifestyle modification interventions in controlling weight. Although further follow-up of this population to evaluate sustainability of change is needed, our results clearly relate improved PA and health.

scholarly journals Physical Activity during Winter in Old-Old Women Associated with Physical Performance after One Year: A Prospective Study

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Atsushi Mizumoto ◽  
Hikaru Ihira ◽  
Keitaro Makino ◽  
Shigeyuki Saitoh ◽  
Hirofumi Ohnishi ◽  
...  
Keyword(s):  
Physical Activity ◽  
Physical Performance ◽  
Repeated Measures ◽  
Walking Speed ◽  
Community Dwelling ◽  
Walking Distance ◽  
Step Counts ◽  
Physical Performances ◽  
Maintenance Group

Background. The aim of this study was to evaluate whether the decline of physical activity during winter influences physical performances (after 1 year) in old-old women.Methods. Fifty-three Japanese women (mean age: 78.4 ± 3.2 years) participated in this study. Data of physical activity was collected by using an accelerometer at baseline and 3-month follow-up, and participants who decreased step counts in this period were defined as declining groups. We measured grip strength, knee extensor strength, total length of the center of gravity, hip walking distance, and maximum walking speed to evaluate physical performances at baseline and 1-year follow-up. Repeated-measures analysis of variance determined the difference in physical performance between declining groups and maintenance group with maintained or improved step counts.Results. Daily step counts for 22 older women (41.5%) decreased during winter. A statistically significant interaction effect between group and time was found for maximum walking speed (F(1,50)=5.23,p=0.03).Post hoccomparisons revealed that walking speed in the maintenance group significantly increased compared with baseline (p=0.01); the declining group showed no significant change (p=0.44).Conclusion. Change of physical activity during winter influences the physical performance level after 1 year in community-dwelling old-old women, particularly its effect on maximum walking speed.

scholarly journals Associations Between Data Driven Dietary Patterns at Age 71 and the Prevalence of Sarcopenia 16 Years Later: A Cohort Study

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 421-421
Author(s):  
Mikael Karlsson ◽  
Wulf Becker ◽  
Tommy Cederholm ◽  
Liisa Byberg
Keyword(s):  
Physical Activity ◽  
Dietary Patterns ◽  
Principal Component ◽  
Fermented Milk ◽  
Activity Level ◽  
Data Driven ◽  
Food Record ◽  
European Working ◽  
High Adherence

Abstract Objectives Unlike physical activity, the role of diet in sarcopenia is unclear, and studies have predominantly focused on effects of single nutrients. Therefore, we assessed the associations between adherences to data driven dietary patterns (DPs), and the prevalence of sarcopenia (and its constituents) 16 years later. Methods Four DPs were defined using principal component analysis based on information from a 7-day food record retrieved from 1133 men (average age 71 years) in the Uppsala Longitudinal Study of Adult Men. Associations of each DP with sarcopenia 16 years later (defined according to the European Working Group on Sarcopenia in Older People; EWGSOP2) were analyzed using multivariable logistic regression (n = 257). Associations of each DP with muscle strength, muscle mass and physical performance 16 years later were analyzed using multivariable linear regression. We applied two models when adjusting for potential confounders: one unadjusted for potential confounders and one adjusted for age at baseline, follow-up period, reported energy intake at baseline, education, physical activity level at baseline, smoking, morbidity at baseline and BMI at baseline. Results The prevalence of sarcopenia at follow-up was 19% (50/257). Associations were largely non-linear and DPs were categorized into low, medium and high adherence. Compared to low adherence, medium and high adherence to DP2 (i.e., vegetables, green salad, fruit, poultry, rice and pasta) was associated with lower odds ratio (OR) of sarcopenia; adjusted ORs: 0.41 (95% confidence interval [CI]: 0.17–0.98) and 0.40 (95% CI: 0.17–0.94), respectively. There was a tendency that a higher adherence to a DP mainly characterized by a consumption of potato, meat and egg, and low consumption of fermented milk (DP4) was associated with higher prevalence of sarcopenia (low vs high adherences; adjusted OR: 1.61, 95% CI: 0.67 - 3.87). The other DPs displayed no clear associations. The analyses of DPs in relation to the individual sarcopenia constituents indicated no clear associations. Conclusions Dietary patterns may be a contributing modifiable cause of sarcopenia. Funding Sources The Uppsala Geriatric Foundation and the Region Örebro County supported this work.

scholarly journals Serum Amino Acids Patterns and 4-Year Sarcopenia Risk in Community-Dwelling Chinese Older Adults

Gerontology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Suey S.Y. Yeung ◽  
Zoe L.Y. Zhu ◽  
Timothy Kwok ◽  
Jean Woo
Keyword(s):  
Older Adults ◽  
Dietary Protein ◽  
Protein Intake ◽  
Principal Component ◽  
Community Dwelling ◽  
Dietary Protein Intake ◽  
Chinese Older Adults ◽  
Serum Amino Acids ◽  
Composite Scores

<b><i>Introduction:</i></b> Dietary protein intake and serum amino acids (AAs) are factors controlling the rate of muscle protein synthesis and catabolism. This study examined the association between serum AAs patterns and incident sarcopenia in community-dwelling older adults. <b><i>Methods:</i></b> Chinese older adults in Hong Kong aged ≥65 years attended a health check at baseline and 4-year follow-up. At baseline, fasting blood was collected to measure 17 serum AAs. Serum AAs patterns were identified using principal component analysis. Dietary protein intake was assessed using a validated food frequency questionnaire. A composite score was computed by summing the principal component score and sex-standardized protein intake. Six composite scores representing each AAs pattern were available for each participant. Sarcopenia was defined using the updated version of the Asian Working Group for Sarcopenia. Crude and adjusted multiple logistic regressions were performed to examine the associations between each of the 6 composite scores and sarcopenia over 4 years. Results are presented as odds ratio (OR) and 95% confidence interval (CI). To address multiple testing, a Bonferroni correction was applied using a corrected significance level of <i>p</i> &#x3c; 0.008 (α 0.05/6 patterns). <b><i>Results:</i></b> Data of 2,610 participants (mean age 71.6 years, 45.4% men) were available. In men, serum AAs patterns characterized by high branched-chain AAs (BCAAs) (OR 0.77, 95% CI 0.69–0.87, <i>p</i> &#x3c; 0.001) and tyrosine, tryptophan, and phenylalanine (OR 0.79, 95% CI 0.71–0.89, <i>p</i> &#x3c; 0.001) were significantly associated with a lower risk of sarcopenia over 4-year follow-up. After adjusting for confounders, the associations were no longer significant. In women, serum AAs patterns characterized by glutamine, glutamic acid, and methionine (OR 1.28, 95% CI 1.11–1.47, <i>p</i> = 0.001) and arginine, taurine, and serine (OR 1.20, 95% CI 1.06–1.35, <i>p</i> = 0.003) were associated with a higher risk of sarcopenia. After adjusting for confounders, serum AAs pattern characterized by high BCAAs (adjusted OR 1.52, 95% CI 1.25–1.86, <i>p</i> &#x3c; 0.001) and arginine, taurine, and serine (adjusted OR 1.30, 95% CI 1.09–1.56, <i>p</i> = 0.004) were significantly associated with a higher risk of sarcopenia. No association between other AAs patterns with incident sarcopenia was found. <b><i>Conclusions:</i></b> In community-dwelling Chinese older adults, serum AAs patterns characterized by high BCAAs and nonessential AAs (arginine, taurine, and serine) were associated with a higher risk of sarcopenia in women. Findings may allow identifying new targets for interventions.

Characterizing Objective and Self-Reported Levels of Physical Activity Among Florida Firefighters Across Weight Status Category: A Cross-Sectional Pilot Study

2020 ◽  
Vol 68 (11) ◽  
pp. 513-518
Author(s):  
Hannah Kling ◽  
Katerina Santiago ◽  
Leonor Benitez ◽  
Natasha Schaefer Solle ◽  
Alberto J. Caban-Martinez
Keyword(s):  
Physical Activity ◽  
Pilot Study ◽  
Repeated Measures ◽  
Weight Status ◽  
Healthy Weight ◽  
Cross Sectional ◽  
The Difference ◽  
Objectively Measured ◽  
Probabilistic Sample

Background: Firefighters suffer from a disproportionally high burden of chronic diseases that could be prevented from regular bouts of physical activity (PA). The goal(s) of this pilot study were to (a) describe typical PA levels in professional paid firefighters, and (b) assess their ability to estimate their own levels of PA. Methods: A repeated measures study design was used to assess self-reported and objectively measured levels of PA from a non-probabilistic sample of firefighters ( n = 18) over 1 week. Objective measures of PA, measured by accelerometry were defined as the number of minutes spent in sedentary, light, moderate, and vigorous PA. Firefighters completed a follow-up questionnaire recording their self-reported levels of PA. Results: Obese (body mass index [BMI] > 30 kg/m2) firefighters spent 8,033 ± 2,543 minutes/week in sedentary activity, overweight (BMI = 25–29 kg/m2) firefighters 6,533 ± 1,587 minutes/week, and healthy weight (BMI = 18.5–24.9 kg/m2) firefighters 5,846 ± 1,160 minutes/week. The difference in self-reported weekly minutes spent in light, moderate, and vigorous activity and objectively measured minutes in activity was calculated. Healthy weight firefighters reported the least difference (1,924 minutes/week), followed by the overweight (3,884 minutes/week) and obese (5,749 minutes/week). Conclusion/Application to Practice: Firefighters poorly estimated their true level of PA compared with their objectively measured PA and obese firefighters reported the greatest inconsistency. Occupational health nurses should aim to support firefighters in achieving PA levels that assist firefighters to achieve a healthy weight and educate them about what it means to be engaged in each level of PA.

scholarly journals Gender-specific risk factors for incident sarcopenia: 8-year follow-up of the English longitudinal study of ageing

2018 ◽  
Vol 73 (1) ◽  
pp. 86-88 ◽  
Author(s):  
Lin Yang ◽  
Lee Smith ◽  
Mark Hamer
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Longitudinal Study ◽  
Large Population ◽  
Community Dwelling ◽  
Inverse Association ◽  
Specific Risk ◽  
Gender Specific ◽  
English Longitudinal Study

BackgroundThe aetiology of age-related sarcopenia is not known.ObjectivesTo investigate if risk of developing sarcopenia differs by gender and to identify gender-specific risk factors of incident sarcopenia in a large population-based cohort of older English adults.MethodsThe sample (n=3404; age 63.4 (SD 7.7) years; 54.1% women) comprised older community-dwelling adults recruited from the English Longitudinal Study of Ageing. Sarcopenia was defined as handgrip <26 kg in men and <16 kg in women. Handgrip strength was assessed at baseline (2004/2005) and repeated at follow-up (2012/2013). Analysed risk factors included baseline anthropometric measures, smoking, vigorous and moderate physical activity, depressive symptoms, chronic illnesses and wealth. After excluding participants with sarcopenia at baseline, multivariable logistic regressions were used to explore baseline risk factors for incident sarcopenia.ResultsDuring 8-year follow-up, 208 and 287 cases of sarcopenia were identified in men (n=1564) and women (n=1840), respectively. Women were at 20% (age adjusted OR=1.20, 95% CI 0.98 to 1.47) higher risk of developing sarcopenia than men. The inverse association between physical activity and sarcopenia risk was observed at moderate (OR=0.44, 95% CI 0.27 to 0.67) and vigorous (0.53, 95% CI 0.31 to 0.82) intensities in men and only vigorous (OR=0.44, 95% CI 0.28 to 0.68) intensity in women. Social factors, such as wealth, and chronic health conditions appeared to be more strongly associated with sarcopenia in men.ConclusionWomen are at higher risk of developing incident sarcopenia than men, and this is likely explained by a range of gender-specific risk factors.

Impact of physical activity, protein intake and social network and their combination on the development of frailty

2019 ◽  
Vol 30 (2) ◽  
pp. 340-346
Author(s):  
Sandra Haider ◽  
Igor Grabovac ◽  
Deborah Drgac ◽  
Christine Mogg ◽  
Moritz Oberndorfer ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Social Network ◽  
Protein Intake ◽  
Community Dwelling ◽  
Adverse Health Outcomes ◽  
Low Protein ◽  
Geriatric Condition ◽  
The Impact

Abstract Background Frailty is a geriatric condition associated with adverse health outcomes. As physical inactivity, low protein intake and poor social network are known risk factors, we aimed to assess the influence of these parameters and their interaction in an 11-year follow-up study on a Europe-wide level. Methods Data from the Study on Health, Ageing and Retirement in Europe were used, including 22 226 community-dwelling robust and prefrail persons aged ≥50 years, from 11 countries. Frailty was assessed with the ‘Frailty Instrument for Primary care of the Survey of Health, Ageing and Retirement in Europe’. Additionally, self-reported physical activity (PA), protein intake and satisfaction with social network were assessed. The impact of these parameters on the development of frailty was calculated using multivariate cox regressions. Results Performing no regular PA, was associated with higher hazards ratio (HRs) for frailty compared with performing regular PA [men: 1.90 (95%CI: 1.50–2.42); women: 1.65 (95%CI: 1.25–2.18)]; HRs for low protein intake were 1.16 (95%CI: 0.93–1.46) for men and 1.05 (95%CI: 0.80–1.37) for women. And HR for poor social network were 0.92 (95%CI: 0.74–1.15) for men and 1.72 (95%CI: 1.31–2.27)] for women. In general, persons with a combination of two of the assessed risk factors had a higher risk for frailty compared with those with no or only one of the risk factors. However, no significant synergy index could be found. Conclusion The results illustrate the importance of PA, but also of nutritional and social network to prevent frailty.

scholarly journals Seasonal Changes in Continuous Sedentary Behavior in Community—Dwelling Japanese Adults: A Pilot Study

Medicines ◽  
2020 ◽  
Vol 7 (9) ◽  
pp. 48
Author(s):  
Chiaki Uehara ◽  
Nobuyuki Miyatake ◽  
Shuhei Hishii ◽  
Hiromi Suzuki ◽  
Akihiko Katayama
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Weight ◽  
Sedentary Behavior ◽  
Seasonal Changes ◽  
Secondary Analysis ◽  
Community Dwelling ◽  
Adverse Health Outcomes ◽  
Japanese Adults

Background: Sedentary behavior (SB) is associated with adverse health outcomes. The aim of this study was to clarify seasonal changes in SB including continuous SB (CSB) in community-dwelling Japanese adults. Methods: In this secondary analysis, a total of 65 community-dwelling Japanese adults (7 men and 58 women, 69 (50–78) years) were enrolled. SB (%), including CSB (≥30 min) as well as physical activity, were evaluated using a tri-accelerometer. The differences in these parameters between baseline (summer) and follow-up (winter) were examined. Results: %CSB and %SB at baseline were 20.5 (4.0–60.9) and 54.0 ± 11.5, respectively. CSB was significantly increased (6.6%), and SB was also increased (5.1%) at follow-up compared with baseline. In addition, there were positive relationships between changes in CSB and SB, and body weight and body mass index. Conclusions: These results suggest that there were significant seasonal changes in CSB and SB in community-dwelling Japanese adults.

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