Risk Factors of Sexual Dysfunction in Patients with Hidradenitis Suppurativa: A Cross-Sectional Study

Dermatology ◽  
2019 ◽  
Vol 236 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Carlos Cuenca-Barrales ◽  
Alejandro Molina-Leyva
Keyword(s):  
Risk Factors ◽  
Sexual Dysfunction ◽  
Disease Activity ◽  
Hidradenitis Suppurativa ◽  
Protective Factor ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stable Relationship

Background: Hidradenitis suppurativa (HS) has a high impact on quality of life. However, sexual health has scarcely been investigated. Objective: To describe the frequency of sexual dysfunction (SD) in women and erectile dysfunction (ED) in men with HS and to explore potential risk factors. Patients and Methods:We conducted a cross-sectional study using a crowd-sourced online questionnaire spread by the Spanish hidradenitis suppurativa patients’ association (ASENDHI). Results: In total, 393 participants answered the questionnaire. SD was found in 51% (95% CI 45–57%) of women and ED in 60% (95% CI 49–70%) of men. Factors related to SD were education status, patient’s global assessment for disease activity, numeric rating scale for pain and unpleasant odour and the absence of a stable relationship. Factors related to ED were increasing age, the presence of active lesions in the genital area and the number of areas affected by active lesions. Conclusions: There is a high prevalence of SD and ED in HS patients. Being in a stable relationship has been a protective factor of SD in women. The results suggest that sexual impairment in HS patients is due, at least in part, to disease activity, symptoms and active lesions.

scholarly journals Toxoplasma gondii infection in pregnant women: a cross-sectional study in Matehuala City, Mexico

BMJ Open ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. e033995
Author(s):  
Ada-Agustina Sandoval-Carrillo ◽  
Angel Antonio Vértiz-Hernández ◽  
Jose-Manuel Salas-Pacheco ◽  
Olga Edith González-Lugo ◽  
Elizabeth-Irasema Antuna-Salcido ◽  
...  
Keyword(s):  
Risk Factors ◽  
Toxoplasma Gondii ◽  
Pregnant Women ◽  
Protective Factor ◽  
Cross Sectional Study ◽  
Secondary Outcome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Infection Age ◽  
Igm Antibodies

ObjectivesThis study aimed to determine the seroprevalence of Toxoplasma gondii (T. gondii) infection in pregnant women in Matehuala City, Mexico; and the associated risk factors.DesignA cross-sectional study.SettingMatehuala City, Mexico.Participants311 pregnant women.Primary and secondary outcome measuresSera of women were analysed for anti-T. gondii IgG and IgM antibodies by commercially available immunoassays. Bivariate and multivariate analyses were used to assess the association between T. gondii seroprevalence and the characteristics of the pregnant women.ResultsThirteen (4.2%) of the 311 pregnant women studied were positive for anti-T. gondii IgG antibodies. No anti-T. gondii IgM antibodies were found in anti-T. gondii IgG seropositive women. No association between seropositivity and history of blood transfusion, transplantation, caesarean sections, deliveries, miscarriages or number of pregnancies was found. Logistic regression analysis of sociodemographic, behavioural and housing variables showed that availability of potable water at street represented a risk factor for T. gondii infection (age-adjusted OR=2.18; 95% CI: 1.05 to 4.53; p=0.03), whereas being born in Mexico was a protective factor for infection (age-adjusted OR=0.01; 95% CI: 0.001 to 0.35; p=0.008).ConclusionsIn this first study on the seroepidemiology of T. gondii infection in pregnant women in Matehuala, we conclude that the seroprevalence of T. gondii infection is low and similar to those reported in pregnant women in other Mexican cities. However, the seroprevalence found is lower than those reported in pregnant women in other countries in the Americas and Europe. Two risk factors associated with T. gondii infection were identified. Results of the present study may help for the optimal planning of preventive measures against toxoplasmosis in pregnant women.

Risk factors, clinical course and long‐term prognosis in hidradenitis suppurativa: a cross‐sectional study

2014 ◽  
Vol 171 (4) ◽  
pp. 819-824 ◽  
Author(s):  
C.B. Kromann ◽  
I.E. Deckers ◽  
S. Esmann ◽  
J. Boer ◽  
E.P. Prens ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hidradenitis Suppurativa ◽  
Clinical Course ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Long Term Prognosis

Disease Activity in Ankylosing Spondylitis and Associations to Markers of Vascular Pathology and Traditional Cardiovascular Disease Risk Factors: A Cross-sectional Study

2015 ◽  
Vol 42 (4) ◽  
pp. 645-653 ◽  
Author(s):  
Inger Jorid Berg ◽  
Désirée van der Heijde ◽  
Hanne Dagfinrud ◽  
Ingebjørg Seljeflot ◽  
Inge Christoffer Olsen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Cross Sectional Study ◽  
Vascular Pathology ◽  
Risk Scores ◽  
Sectional Study ◽  
Cvd Risk ◽  
Cross Sectional

Objective.To compare the risk of cardiovascular disease (CVD) in ankylosing spondylitis (AS) and population controls, and to examine the associations between disease activity and CVD risk.Methods.A cross-sectional study was done of patients with AS grouped according to Ankylosing Spondylitis Disease Activity Score (ASDAS) into ASDAS-high and ASDAS-low. Markers of vascular pathology, impaired endothelial function [asymmetric dimethylarginine (ADMA)], and arterial stiffness [augmentation index (AIx) and pulse wave velocity (PWV)], and traditional CVD risk factors [blood pressure, lipids, body mass index (BMI), CVD risk scores] were compared between AS and controls as well as across ASDAS-high versus ASDAS-low versus controls using ANCOVA analyses.Results.Altogether, 151 patients with AS and 134 controls participated. Patients had elevated ADMA (µmol/l) and AIx (%) compared to controls: mean difference (95% CI): 0.05 (0.03, 0.07), p < 0.001 and 2.6 (0.8, 4.3), p = 0.01, respectively. AIx increased with higher ASDAS level, p(trend) < 0.04. There were no significant group differences of PWV. BMI was higher in ASDAS-high compared to ASDAS-low (p = 0.02). Total cholesterol was lower in AS compared to controls, and lower with higher ASDAS, p(trend) = 0.02. CVD risk scores were similar across groups except for Reynolds Risk Score, where the ASDAS-high group had a significantly higher score, compared to both ASDAS-low and controls.Conclusion.Elevated ADMA and AIx in AS support a higher CVD risk in AS. Elevated AIx and BMI in AS with high ASDAS indicate an association between disease activity and CVD risk. Lower total cholesterol in AS may contribute to underestimation of CVD risk.

Beneficial effect of Mediterranean diet on disease activity and cardiovascular risk in systemic lupus erythematosus patients: a cross-sectional study

Rheumatology ◽  
2020 ◽  
Vol 60 (1) ◽  
pp. 160-169 ◽  
Author(s):  
Gabriela Pocovi-Gerardino ◽  
María Correa-Rodríguez ◽  
José-Luis Callejas-Rubio ◽  
Raquel Ríos-Fernández ◽  
María Martín-Amada ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Disease Activity ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Damage Accrual ◽  
Diet Score

Abstract Objective To analyse the influence of the Mediterranean diet (Med Diet) on SLE activity, damage accrual and cardiovascular disease risk markers. Methods A cross-sectional study was conducted on 280 patients with SLE [46.9 (12.85) years]. Med Diet adherence was assessed through a 14-item questionnaire on food consumption frequency and habits (total score from 0 to 14 points; higher score is greater adherence to the Med Diet). CRP, homocysteine, SLEDAI-2K (SLE disease activity), and SLICC/ACR and SDI (damage accrual) were measured. Obesity, diabetes mellitus, hypertension and blood lipids, among others, were considered cardiovascular disease risk factors. Results Greater adherence to the Med Diet was significantly associated with better anthropometric profiles, fewer cardiovascular disease risk factors, and lower disease activity and damage accrual scores (P ≤ 0.001 for SLEDAI and SDI). An inverse relationship between the Med Diet score and SLEDAI (P ≥ 0.001; β = −0.380), SDI (P ≤ 0.001; β = −0.740) and hsCRP (P = 0.039; β = −0.055) was observed. The odds ratio for having active SLE (SLEDAI ≥5) or the presence of damage (SDI ≥1) was lower among patients whose Med Diet score was higher (P ≤ 0.001). Finally, greater consumption of Med Diet foods (olive oil, fruits, vegetables, fish, etc.) and abstaining from red meat and meat products, sugars and pastries was associated with less SLE clinical activity and damage. Conclusion Greater adherence to the Med Diet seems to exert a beneficial effect on disease activity and cardiovascular risk in SLE patients. To confirm these findings, further longitudinal studies would be of interest.

scholarly journals Sexual Distress in Patients with Hidradenitis Suppurativa: A Cross-Sectional Study

2019 ◽  
Vol 8 (4) ◽  
pp. 532 ◽  
Author(s):  
Carlos Cuenca-Barrales ◽  
Ricardo Ruiz-Villaverde ◽  
Alejandro Molina-Leyva
Keyword(s):  
Hidradenitis Suppurativa ◽  
Rating Scale ◽  
Multiple Linear Regression Model ◽  
Numeric Rating Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Sexual Distress ◽  
The Impact

Hidradenitis suppurativa (HS) is a chronic auto-inflammatory skin disease with a great impact in quality of life. However, there is little research about the impact of HS on sex life. The aims of this study are to describe the frequency of sexual distress (SD) in patients with HS and to explore potentially associated epidemiological and clinical factors. We conducted a cross-sectional study by means of a crowd-sourced online questionnaire hosted by the Spanish hidradenitis suppurativa patients’ association (ASENDHI). Sexual distress (SD) was evaluated with a Numeric Rating Scale (NRS) for HS impact on sex life. A total of 393 participants answered the questionnaire. The mean NRS for HS impact on sex life was 7.24 (2.77) in women and 6.39 (3.44) in men (p < 0.05). Variables significantly associated (p < 0.05) with SD in the multiple linear regression model were sex, with a higher risk in females, the presence of active lesions in the groin and genitals and NRS for pain and unpleasant odor; being in a stable relationship was an important protector factor. Regarding these results, it seems that SD in HS patients is due, at least in part, to disease symptoms and active lesions in specific locations, emphasizing the importance of disease control with a proper treatment according to management guidelines. Women and single patients are more likely to suffer from sexual distress.

scholarly journals Risk factors associated with female sexual dysfunction among married women in Upper Egypt; a cross sectional study

2018 ◽  
Vol 5 (2) ◽  
pp. 449
Author(s):  
Ahmed E. Arafa ◽  
Rasha S. Elbahrawe ◽  
Sherwet M. Shawky ◽  
Alshimaa M. Mostafa ◽  
Safaa S. Ahmed ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexual Dysfunction ◽  
Potential Risk ◽  
Female Sexual Dysfunction ◽  
Cross Sectional Study ◽  
Negative Consequences ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Potential Risk Factors

Background: Female sexual dysfunction (FSD) has many psychological and social negative consequences. The aim of this study is to detect the potential risk factors associated with FSD among sexually active women in Beni-Suef, Egypt. Methods: A multi-stage random sampling methodology was used to include 490 premenopausal women, residing in Beni-Suef, in this cross-sectional study. FSD was measured using the Arabic version of the female sexual function index (ArFSFI), throughout an interview. It includes 6 domains; desire, arousal, lubrication, orgasm, satisfaction and pain. The questions in each domain have five to six choices with a score ranging between zero and five. Results: Age, years of marriage and number of pregnancies correlated negatively with ArFSFI total score (p<0.05). Higher body mass index was associated with lower scores of desire, arousal and lubrication (p<0.05). Compared to those with constant job, unemployed women had lower scores of desire and arousal (p<0.05). No statistically significant associations have been detected between circumcision and any of the studied ArFSFI domains (p>0.05). Conclusions: There are many potential risk factors suggested to be associated with FSD. Further studies should focus on understanding the adaptive strategies used by women to get over their FSD problems. Barriers preventing women with FSD from seeking treatment should also be investigated. 

scholarly journals Hubungan Usia dan Paritas dengan Kejadian Preeklampsia Berat di Rumah Sakit Achmad Mochtar Bukittinggi Tahun 2012 - 2013

2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Siqbal Karta Asmana ◽  
Syahredi Syahredi ◽  
Noza Hilbertina
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Significant Relationship ◽  
Protective Factor ◽  
Cross Sectional Study ◽  
Severe Preeclampsia ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

AbstrakPreeklampsia dapat menimbulkan berbagai komplikasi yang membahayakan bagi ibu dan janin, sehingga dapat menimbulkan kematian.  Beberapa faktor risiko seperti usia yang ekstrem (<20 &>35 tahun) dan nuliparitas. Keduanya merupakan faktor risiko yang tidak dapat dimodifikasi. Tujuan  penelitian ini adalah menentukan hubungan usia dan paritas dengan kejadian preeklampsia berat. Telah dilakukan penelitian di Bagian Rekam Medis Rumah Sakit Achmad Mochtar Bukittinggi terhadap data semua pasien rawat inap obstetri dan ginekologi tahun 2012 – 2013.  Penelitian menggunakan metode analitik dengan desain cross sectional study. Analisis penelitian menggunakan ratio prevalence dan chi-square test dengan derajat kepercayaan 95%. Penelitian ini menemukan 162 kasus (4,99%) preeklampsia berat. Proporsi kasus terbesar ditemukan pada kelompok usia ekstrem (9,90%) dan kelompok multiparitas (8,68%). Analisis ratio prevalence menyimpulkan bahwa usia ekstrem merupakan faktor risiko preeklampsia berat (RP= 1,476; CI= 1,094 – 1,922), dan nuliparitas belum dapat ditentukan apakah merupakan faktor risiko atau faktor protektif (RP= 0,765; CI= 0,565 – 1,034). Berdasarkan analisis dengan chi-square test, disimpulkan bahwa terdapat hubungan yang bermakna antara usia dengan preeklampsia berat (p= 0,014<0,05) dan tidak terdapat hubungan yang bermakna antara paritas dengan preeklampsia berat (p= 0,096>0,05).Kata kunci: preeklampsia, faktor risiko, usia, paritas AbstractPreeclampsia can cause the complication that endanger maternal and fetal, until death. There are many risk factors like extreme age (<20 & >35 years) and nuliparity that can not modify. The objective of this study was to  determine the relationship of maternal age and parity to the incidence of severe preeclampsia.  The research conducted at Medical Record Division of Achmad Mochtar Hospital Bukittinggi about data of all hospitalized patients of obstetrics and gynecology on 2012 – 2013. This research used the analytical method with cross sectional study. Analysis of this research used ratio prevalence and chi-square test with degree of confidence 95%. This research  found 162 case (4.99%) severe preeclampsia. The highest proportion of this case was the extreme age groups (9.90%) and multiparity group (8.68%). Analysis with the ratio prevalence concluded that extreme age is a risk factor for severe preeclampsia (RP=1.476; CI= 1.094 – 1.922) and nuliparity can not determined wheather a risk factor or protective factor (RP= 0.765; CI= 0.565 – 1.034). Analysis with chi-square test concluded that there is a significant relationship between age with severe preeclampsia (p= 0.014<0.05) and there is no significant relationship between parity with severe preeclampsia (p= 0.096>0.05).Keywords: preeclampsia, risk factors, age, parity

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