Metals and female reproductive toxicity

2014 ◽  
Vol 34 (7) ◽  
pp. 679-697 ◽  
Author(s):  
P Sengupta ◽  
R Banerjee ◽  
S Nath ◽  
S Das ◽  
S Banerjee
Keyword(s):  
Pregnant Woman ◽  
Menstrual Cycle ◽  
Occupational Exposure ◽  
Reproductive Health ◽  
Occupational Health ◽  
Reproductive Toxicity ◽  
Early Research ◽  
Hormonal Changes ◽  
Reproductive Systems ◽  
Reproductive Toxins

Research into occupational exposure of metals and consequences of reproductive systems has made imperative scientific offerings in the preceding few decades. Early research works focused on possible effects on the reproductive functions rather than the complete reproductive health of the woman. Later, it was realized that metals, as reproductive toxins, may also induce hormonal changes affecting other facets of reproductive health such as the menstrual cycle, ovulation, and fertility. Concern is now shifting from considerations for the pregnant woman to the entire spectrum of occupational health threats and thus reproductive health among women.

scholarly journals Reproductive Health Issues

AAOHN Journal ◽  
1992 ◽  
Vol 40 (2) ◽  
pp. 72-77
Author(s):  
Patricia E. Hunt
Keyword(s):  
Reproductive Health ◽  
Occupational Health ◽  
Health Professionals ◽  
Health Issues ◽  
Reproductive Toxins

Occupational health nurses and other health professionals are at the forefront of the issues of reproductive health in the workplace. Many complexities are involved, and the best information available may be inconclusive. Thus, these issues represent a challenging area where occupational health nurses can make important contributions. A great accountability for communication about reproductive toxins falls on occupational health professionals. They must make every effort to be knowledgeable, to control workplace risks for everyone, and to educate and counsel employees on reproductive issues in the workplace.

CHANGES IN THE CONCENTRATION OF PITUITARY AND STEROID HORMONES IN THE FOLLICULAR FLUID OF HUMAN GRAAFIAN FOLLICLES THROUGHOUT THE MENSTRUAL CYCLE

1975 ◽  
Vol 64 (3) ◽  
pp. 555-571 ◽  
Author(s):  
K. P. McNATTY ◽  
W. M. HUNTER ◽  
A. S. McNEILLY ◽  
R. S. SAWERS
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Follicular Fluid ◽  
Follicle Stimulating Hormone ◽  
Secretory Activity ◽  
Follicular Phase ◽  
Hormonal Changes ◽  
Peripheral Plasma ◽  
Before And After ◽  
Late Follicular Phase

SUMMARY The concentrations of FSH, LH, prolactin, oestradiol and progesterone were measured in peripheral plasma and follicular fluid of women throughout the menstrual cycle. With the exception of prolactin, concentrations of pituitary and steroid hormones in follicular fluid correlated with those in peripheral plasma. Follicle-stimulating hormone was present in a greater number of small follicles ( < 8 mm) during or just after the peaks of FSH in peripheral plasma. During the mid-follicular phase the concentration of both FSH and oestradiol in fluid from large follicles ( ≥ 8 mm) was high. During the late follicular phase the large follicles ( ≥ 8 mm) contained high amounts of progesterone in addition to oestradiol, low physiological levels of prolactin, and concentrations of LH and FSH about 30 and 60% respectively of those found in plasma. By contrast no large 'active' follicles ( ≥ 8 mm) were found during the luteal phase although many contained both LH and FSH. Luteinizing hormone was present in a proportion of small follicles ( < 8 mm) during the late follicular and early luteal but not at other stages of the menstrual cycle. It is suggested that a precise sequence of hormonal changes occur within the microenvironment of the developing Graafian follicle; the order in which they occur may be of considerable importance for the growth of that follicle and secretory activity of the granulosa cells both before and after ovulation.

Occupational exposure to chemicals and reproductive health

2011 ◽  
pp. 949-959 ◽  
Author(s):  
Helena Taskinen ◽  
Marja-Liisa Lindbohm ◽  
Markku Sallmén
Keyword(s):  
Occupational Exposure ◽  
Reproductive Health

scholarly journals Occupational exposure to particles and air pollutants in a car paint workshop

2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
Ana Ferreira ◽  
António Loureiro ◽  
Silvia Seco ◽  
João Paulo Figueiredo ◽  
Susana Paixão ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Air Quality ◽  
Occupational Exposure ◽  
Occupational Health ◽  
Air Pollutants ◽  
Statistical Tests ◽  
Well Being ◽  
Atmospheric Pollutants ◽  
Inhalable Particles ◽  
The Government

Abstract Background In auto paint workshops there are several chemical, physical and biological agents that are harmful to health, making it essential to guarantee the well-being and safety of workers. In this sense, the assessment of the Indoor Air Quality (IAQ) of these places, in an associated context of occupational health, proves to be important. Methods The present study had as main objective to evaluate the occupational exposure of workers in an automobile painting workshop to particles and air pollutants. The data collection consisted of the evaluation of air quality, using for this purpose, the assessment of atmospheric pollutants carbon monoxide (CO), carbon dioxide (CO2), Volatile Organic Compounds (VOC), formaldehyde (CH2O), carbon dioxide sulfur (SO2), nitrogen dioxide (NO2), hydrogen sulfide (H2S) and particulate matter (PM2.5, PM10, breathable and inhalable particles) and the meteorological variables temperature and relative humidity. The collected data was processed using the statistical software IBM SPSS version 27.0. The interpretation of the statistical tests was performed with a 95% confidence level for a maximum random error up to 5%. Results We found that the concentrations of inhalable particles recorded in some workstations exceeded the legally established exposure limit value. Conclusions IAQ should be a priority concern for the government and for all professionals working in the area of Occupational Health and Safety having in mind the implementation of measures that promote the continuous improvement of the IAQ of the facilities, thus guaranteeing a good assessment and monitoring of workstations, preventing atmospheric pollutants from reaching concentrations that could put workers' health at risk.

scholarly journals HUBUNGAN ANTARA TINGKAT KEPARAHAN PMS DENGAN TINGKAT KECEMASAN DAN KUALITAS TIDUR PADA REMAJA PUTRI

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Henny Dwi Susanti ◽  
Reni Ilmiasih ◽  
Ari Arvianti
Keyword(s):  
Menstrual Cycle ◽  
Sampling Technique ◽  
Physical Symptoms ◽  
Hormonal Changes ◽  
Cross Sectional ◽  
Quality Sleep ◽  
Current Cycle ◽  
Positive Correlation Coefficient ◽  
The Relationship

Abstract : Pre Menstrual Syndrome (PMS) is a collection of physical symptoms, psychological, and emotions associated with the woman's menstrual cycle and consistently occur during the luteal phase of the menstrual cycle due to hormonal changes associated with the current cycle of ovulation (release of eggs from the ovary) and menstruation. Some of the complaints were felt during PMS, such as headache, back pain, breast pain, sleep disorders, and more than a few complaints can cause anxiety in women with PMS. This research was conducted observational analytic with cross sectional method. levels of anxiety and sleep quality in adolescent girls (as dependent variable). The sample used in this research were 30 students. Total sampling is a sampling technique in which the number of samples is equal to the population. there is a significant correlation between the severity of PMS with the level of anxiety. A positive correlation coefficient indicates that the relationship between the severity of PMS with anxiety levels. The more severe or severe PMS level, the level of anxiety is also heavier. Conversely, the mild severity of PMS, the anxiety level is also lighter. There is a significant correlation between the severity of PMS with the quality of sleep.Keywords : severity PMS, level of anxiety, quality sleep, adult Abstrak : Pre Menstrual Syndrome (PMS) merupakan kumpulan gejala fisik, psikologis, dan emosi yang terkait dengan siklus menstruasi wanita dan secara konsisten terjadi selama tahap luteal dari siklus menstruasi akibat perubahan hormonal  yang berhubungan dengan siklus saat ovulasi (pelepasan sel telur dari ovarium) dan menstruasi. Beberapa keluhan yang dirasakan saat PMS yaitu sakit kepala, sakit punggung, nyeri pada payudara, gangguan tidur, dan lain-lain.Akibat dari beberapa keluhan yang dirasakantersebut dapat menimbulkan kecemasan pada wanita yang mengalami PMS. Penelitian ini dilakukan secara observasional analitik dengan metode pendekatan cross sectional. tingkat kecemasan dan kualitas tidur pada remaja putri (sebagai variabel dependen). Sampel yang digunakan dalam penelitian ini berjumlah 30 siswi. Total sampling adalah teknik pengambilan sampel dimana jumlah sampel sama dengan populasi. terdapat hubungan yang signifikan antara tingkat keparahan PMS dengan tingkat kecemasan. Koefisien korelasi yang positif menunjukkan bahwa hubungan antara tingkat keparahan PMS dengan tingkat kecemasan. Semakin parah atau berat tingkat PMS, maka tingkat kecemasan juga semakin berat. Sebaliknya, semakin ringan tingkat keparahan PMS, maka tingkat kecemasan juga semakin ringan. Terdapat hubungan yang signifikan antara tingkat keparahan PMS dengan kualitas tidur.Kata kunci : tingkat keparahan,PMS, tingkat kecemasan, kualitas tidur, remaja.

scholarly journals CRITICAL REVIEW OF JYOTISHMATYADI YOGA IN NASHTARTAVA

2021 ◽  
Vol 9 (8) ◽  
pp. 1824-1830
Author(s):  
Swati Malsariya ◽  
Bharathi K. ◽  
Pushpalatha B.
Keyword(s):  
Menstrual Cycle ◽  
Critical Review ◽  
Physical State ◽  
Physical Stress ◽  
Hormonal Changes ◽  
Health Issues ◽  
Menstrual Disorders ◽  
Secondary Amenorrhea ◽  
Day By Day

The female undergoes dramatic monthly hormonal changes during each menstrual cycle affecting her emotional and physical state. During these changes sometimes she suffers from some gynaecological problems Nashtartava is one of them. As per classics, Nashtartava is considered as an Avaranajanya Vyadhi in which female suffers from Yathochita kale Adarshanam (Delayed menses/absence of menses), Alparta (scanty flow) and Yonivedana (painful menses). This condition can be compared with oligomenorrhoea or secondary amenorrhea. The ratio of such kinds of menstrual disorders is rising day by day which becomes a precursor of other health issues like infertility, mental and physical stress, etc. Oligomenorrhoea or infrequent menstruation, usually present in a woman with secondary symptoms like acne, obesity, dandruff, infertility etc. so treatment of Nashtartava is very necessary. For its treatment, the use of Agneya and Vata Kapha Shamaka Dravya is mentioned in the classics. Acharya Bhavmishra indicates the use of Jyotishmatiyadi Yoga for the management of Yonidosha along with Nashtartava. Jyotishmatyadi Yoga having Katu, Tikta Rasa, Tikshana Guna, Ushna Virya and Katu Viapaka and Vata Kapha shamaka property so effectively act on Nashtartava. Keywords: Nashtartava, Oligomenorrhoea, Jyotishmatyadi Yoga, Artava

scholarly journals Pesticides as endocrine distruptors of the reproductive system (literature review and own research)

2021 ◽  
pp. 49-62
Author(s):  
Ninel Shepelska ◽  
Mykola Prodanchuk ◽  
Yana Kolianchuk
Keyword(s):  
Reproductive Health ◽  
Endocrine Disruptors ◽  
Reproductive System ◽  
Reproductive Toxicity ◽  
Endocrine System ◽  
Reproductive Function ◽  
Dose Dependence ◽  
Animal Cells ◽  
Wide Range ◽  
The Impact

Currently, one of the main threats to human health is undoubtedly endocrine disruptors (ED), since they directly disrupt the processes of homeostasis maintenance, controlled by the endocrine system, the purpose of which is to maintain normal functions and development in a constantly changing environment. Pesticides can disrupt the physiological functioning of many endocrine axes, including the endocrine mechanisms that ensure reproductive health. It should be noted that research aimed at preventing chemically induced reproductive disorders in the human population is one of the central areas of preventive medicine, both in terms of their importance and the complexity of the tasks being solved. Analysis and generalization of the results of our own long-term studies have shown that the selective, and, therefore, the most dangerous toxicity of pesticides for the reproductive system is determined by endocrine-mediated mechanisms of etiopathogenesis. The low level of doses inducing pathological changes in reproductive function in our studies fully confirms one of the universal signs inherent in endocrine-distruptive compounds. The above examples demonstrate a wide range of possible endocrine-mediated mechanisms of reproductive toxicity of pesticides - endocrine disruptors. However, it is very important to note that low doses may be more effective in changing some endpoints compared to high (toxic) doses. Currently, several mechanisms have been identified and studied that demonstrate how hormones and ED induce non-monotonic reactions in animal cells, tissues and organs. The reproductive system, the functioning of which is ensured by a fine balancing of the action of androgens and estrogens, is one of the systems that presents a unique opportunity for modeling a non-monotonic dose dependence. All of the above indicates the extreme danger of the impact of hormonally active agents on the reproductive health of a person and his offspring. At the same time, the threat of endocrine-mediated disorders for subsequent generations can also be realized through the induction of mechanisms of development of epigenetic transgenerational effects. Taking into account the results of studies of the mechanisms of the ED destructive action, as well as their ability to induce non-monotonic dose dependence at an extremely low dose level, it should be admitted that, apparently, there is a need to revise the paradigm of methodological approaches to the regulation of pesticides with endocrine-disruptive properties. Key words: pesticides, endocrine disruptors, reproductive system

scholarly journals SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Ann-Sofie Rudberg ◽  
Sebastian Havervall ◽  
Anna Månberg ◽  
August Jernbom Falk ◽  
Katherina Aguilera ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
Occupational Health ◽  
Acute Care ◽  
Odds Ratio ◽  
Healthcare Workers ◽  
Acute Care Hospital ◽  
Care Hospital ◽  
Patient Contact ◽  
Igg Antibodies ◽  
Time Period

Abstract SARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthcare workers at a large acute care hospital in Sweden. The seroprevalence of IgG antibodies against SARS-CoV-2 was 19.1% among the 2149 healthcare workers recruited between April 14th and May 8th 2020, which was higher than the reported regional seroprevalence during the same time period. Symptoms associated with seroprevalence were anosmia (odds ratio (OR) 28.4, 95% CI 20.6–39.5) and ageusia (OR 19.2, 95% CI 14.3–26.1). Seroprevalence was also associated with patient contact (OR 2.9, 95% CI 1.9–4.5) and covid-19 patient contact (OR 3.3, 95% CI 2.2–5.3). These findings imply an occupational risk for SARS-CoV-2 infection among healthcare workers. Continued measures are warranted to assure healthcare workers safety and reduce transmission from healthcare workers to patients and to the community.

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