An Exploratory Study of a Masking Strategy of Cyberdeception Using CyberVAN

2020 ◽  
Vol 64 (1) ◽  
pp. 446-450
Author(s):  
Palvi Aggarwal ◽  
Omkar Thakoor ◽  
Aditya Mate ◽  
Milind Tambe ◽  
Edward A. Cranford ◽  
...  
Keyword(s):  
Risk Aversion ◽  
Learning Process ◽  
Exploratory Study ◽  
State Of The Art ◽  
Random Condition ◽  
Experimental Conditions ◽  
Current State ◽  
Exploratory Experiment ◽  
Human Participants

During the network reconnaissance process, attackers scan the network to gather information before launching an attack. This is a good chance for defenders to use deception and disrupt the attacker’s learning process. In this paper, we present an exploratory experiment to test the effectiveness of a masking strategy (compared to a random masking strategy) to reduce the utility of attackers. A total of 30 human participants (in the role of attackers) are randomly assigned to one of the two experimental conditions: Optimal or Random (15 in each condition). Attackers appeared to be more successful in launching attacks in the optimal condition compared to the random condition but the total score of attackers was not different from the random masking strategy. Most importantly, we found a generalized tendency to act according to the certainty bias (or risk aversion). These observations will help to improve the current state-of-the-art masking algorithms of cyberdefense.

scholarly journals Geomorphometry: Today and Tomorrow

2018 ◽  
Author(s):  
John P Wilson
Keyword(s):  
Content Knowledge ◽  
State Of The Art ◽  
High Fidelity ◽  
Terrain Modeling ◽  
Actionable Knowledge ◽  
Digital Terrain ◽  
Current State ◽  
Digital Terrain Modeling ◽  
Key Innovations

This paper summarizes the current state-of-the-art in geomorphometry and describes the innovations that are close at hand and will be required to push digital terrain modeling forward in the future. These innovations will draw on concepts and methods from computer science and the spatial sciences and require greater collaboration to produce “actionable” knowledge and outcomes. The key innovations include rediscovering and using what we already know, developing new digital terrain modeling methods, clarifying and strengthening the role of theory, developing high-fidelity DEMs, developing and embracing new visualization methods, adopting new computational approaches, and making better use of provenance, credibility, and application-content knowledge.

The growing role of structural mass spectrometry in the discovery and development of therapeutic antibodies

The Analyst ◽  
2018 ◽  
Vol 143 (11) ◽  
pp. 2459-2468 ◽  
Author(s):  
Yuwei Tian ◽  
Brandon T. Ruotolo
Keyword(s):  
Mass Spectrometry ◽  
State Of The Art ◽  
Therapeutic Antibodies ◽  
Critical Importance ◽  
Current State ◽  
Measurement Science ◽  
Structural Mass Spectrometry ◽  
Structural Mass

The comprehensive structural characterization of therapeutic antibodies is of critical importance for the successful discovery and development of such biopharmaceuticals, yet poses many challenges to modern measurement science. Here, we review the current state-of-the-art mass spectrometry technologies focusing on the characterization of antibody-based therapeutics.

scholarly journals Practice-oriented Learning as a Way to Meet Employers’ Requirements to Graduates

2014 ◽  
Vol 4 (2) ◽  
pp. 31 ◽  
Author(s):  
Alexander Chuchalin ◽  
Mikhail Minin ◽  
Natalia Vyuzhanina
Keyword(s):  
Engineering Education ◽  
Labour Market ◽  
Learning Process ◽  
Real World ◽  
Education System ◽  
Learning Technologies ◽  
Current State ◽  
Main Indicator

The article considers the current state of engineering education in Europe in general and in Russia in particular in the light of the need to meet employers’ requirement to graduates, and the role of practice-oriented learning technologies in this process. The demand for graduates on the labour market and their competitiveness is seen as the main indicator of the education system ability to react and adapt to the market demands. Thus the employers’ requirements should be one of the most important drivers for the learning process. And the practice-oriented learning technologies are given as the most effective answer to these needs as they imply involvement of the employer and solution of real-world tasks and problems.

scholarly journals Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

2011 ◽  
Vol 68 (16) ◽  
pp. 2667-2688 ◽  
Author(s):  
Bence György ◽  
Tamás G. Szabó ◽  
Mária Pásztói ◽  
Zsuzsanna Pál ◽  
Petra Misják ◽  
...  
Keyword(s):  
Extracellular Vesicles ◽  
State Of The Art ◽  
Membrane Vesicles ◽  
Current State

scholarly journals Nanoarchitectonics: Complexes and Conjugates of Platinum Drugs with Silicon Containing Nanocarriers. An Overview

2021 ◽  
Vol 22 (17) ◽  
pp. 9264
Author(s):  
Kinga Piorecka ◽  
Jan Kurjata ◽  
Wlodzimierz A. Stanczyk
Keyword(s):  
Drug Delivery ◽  
Driving Force ◽  
State Of The Art ◽  
Platinum Drugs ◽  
Research Groups ◽  
Current State ◽  
Delivery Platform ◽  
Silicon Based ◽  
Intensive Search

The development in the area of novel anticancer prodrugs (conjugates and complexes) has attracted growing attention from many research groups. The dangerous side effects of currently used anticancer drugs, including cisplatin and other platinum based drugs, as well their systemic toxicity is a driving force for intensive search and presents a safer way in delivery platform of active molecules. Silicon based nanocarriers play an important role in achieving the goal of synthesis of the more effective prodrugs. It is worth to underline that silicon based platform including silica and silsesquioxane nanocarriers offers higher stability, biocompatibility of such the materials and pro-longed release of active platinum drugs. Silicon nanomaterials themselves are well-known for improving drug delivery, being themselves non-toxic, and versatile, and tailored surface chemistry. This review summarizes the current state-of-the-art within constructs of silicon-containing nano-carriers conjugated and complexed with platinum based drugs. Contrary to a number of other reviews, it stresses the role of nano-chemistry as a primary tool in the development of novel prodrugs.

Cardiovascular Risk in Psoriasis: Current State of the Art

2018 ◽  
Vol 17 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Giuseppe Dattilo ◽  
Francesco Borgia ◽  
Claudio Guarneri ◽  
Matteo Casale ◽  
Roberto Bitto ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cardiovascular Risk ◽  
Skin Disease ◽  
Independent Risk Factor ◽  
Clinical Laboratory ◽  
State Of The Art ◽  
Mortality And Morbidity ◽  
Current State ◽  
Immune Mediated

Psoriasis (Pso) is a chronic inflammatory immune-mediated skin disease associated with several comorbidities. Despite the growing number of studies providing evidence for the link between Pso and Cardiovascular (CV) disorders, there are still many unsolved questions, dealing with the role of the skin disease as an independent risk factor for CV events, the influence of Pso severity and duration on CV damage, the presence of Psoriatic Arthritis (PsA) as a predictor of increased CV mortality and morbidity and the detection of reliable clinical, laboratory and/or instrumental parameters to stratify CV risk in psoriatic patients. Moreover, it remains to clarify if the early treatment of the dermatosis may lower CV risk. In this paper we will try to provide answers to these queries in the light of the updated data of the literature.

You Need Teachers

PEDIATRICS ◽  
1979 ◽  
Vol 64 (1) ◽  
pp. 125-125
Author(s):  
Miles Weinberger
Keyword(s):  
State Of The Art ◽  
Review Article ◽  
Current State ◽  
Children With Asthma ◽  
Degree Of Control ◽  
Considerable Morbidity ◽  
High Degree ◽  
Changing Role ◽  
Excellent Review Article

The excellent review article by Leffert1 and the accompanying commentary by Bergner2 made important points regarding the changing role of the pediatric allergist and the broad requirements for knowledge of any physicians who are to provide specialty care for children with asthma. While the current state of the art allows a high degree of control for this disease,3 considerable morbidity from inadequately treated asthma persists. This situation is unlikely to change rapidly unless departments of pediatrics place a high priority on ensuring that the modern allergist described by Dr. Bergner is on their faculty to teach the current housestaff and provide continuing education for the practitioner; only then will most general pediatricians be able to assume the role envisioned by Dr. Leffert.

scholarly journals Detection of regularities in a random environment

2020 ◽  
Vol 73 (12) ◽  
pp. 2106-2118
Author(s):  
Arnaud Rey ◽  
Louisa Bogaerts ◽  
Laure Tosatto ◽  
Guillem Bonafos ◽  
Ana Franco ◽  
...  
Keyword(s):  
Statistical Learning ◽  
Contextual Information ◽  
Critical Role ◽  
Naming Task ◽  
Variable Number ◽  
Experimental Conditions ◽  
Human Participants ◽  
New Evidence ◽  
Repetition Task

Regularity detection, or statistical learning, is regarded as a fundamental component of our cognitive system. To test the ability of human participants to detect regularity in a more ecological situation (i.e., mixed with random information), we used a simple letter-naming paradigm in which participants were instructed to name single letters presented one at a time on a computer screen. The regularity consisted of a triplet of letters that were systematically presented in that order. Participants were not told about the presence of this regularity. A variable number of random letters were presented between two repetitions of the regular triplet, making this paradigm similar to a Hebb repetition task. Hence, in this Hebb-naming task, we predicted that if any learning of the triplet occurred, naming times for the predictable letters in the triplet would decrease as the number of triplet repetitions increased. Surprisingly, across four experiments, detection of the regularity only occurred under very specific experimental conditions and was far from a trivial task. Our study provides new evidence regarding the limits of statistical learning and the critical role of contextual information in the detection (or not) of repeated patterns.

scholarly journals Membrane proteins, detergents and crystals: what is the state of the art?

2014 ◽  
Vol 70 (12) ◽  
pp. 1576-1583 ◽  
Author(s):  
Patrick J. Loll
Keyword(s):  
Membrane Protein ◽  
Critical Parameter ◽  
State Of The Art ◽  
Protein Crystal ◽  
Direct Crystallization ◽  
Current State ◽  
Protein Crystal Structure ◽  
Technical Advances ◽  
Screening Approaches

At the time when the first membrane-protein crystal structure was determined, crystallization of these molecules was widely perceived as extremely arduous. Today, that perception has changed drastically, and the process is regarded as routine (or nearly so). On the occasion of the International Year of Crystallography 2014, this review presents a snapshot of the current state of the art, with an emphasis on the role of detergents in this process. A survey of membrane-protein crystal structures published since 2012 reveals that the direct crystallization of protein–detergent complexes remains the dominant methodology; in addition, lipidic mesophases have proven immensely useful, particularly in specific niches, and bicelles, while perhaps undervalued, have provided important contributions as well. Evolving trends include the addition of lipids to protein–detergent complexes and the gradual incorporation of new detergents into the standard repertoire. Stability has emerged as a critical parameter controlling how a membrane protein behaves in the presence of detergent, and efforts to enhance stability are discussed. Finally, although discovery-based screening approaches continue to dwarf mechanistic efforts to unravel crystallization, recent technical advances offer hope that future experiments might incorporate the rational manipulation of crystallization behaviors.

scholarly journals Identification of Key Actors of Agricultural Community-Based Organization from Communication Perspective in Malaysia

2014 ◽  
Vol 23 ◽  
pp. 66-72
Author(s):  
N.N.M. Shariff ◽  
A. Muhammad ◽  
Zety Sharizat Hamidi
Keyword(s):  
Sustainable Agriculture ◽  
Learning Process ◽  
Knowledge Network ◽  
Agricultural Practice ◽  
Community Based ◽  
Agricultural Knowledge ◽  
Current State ◽  
Agricultural Community ◽  
Community Based Organization

This paper was part of a larger study which focuses on communication aspect of sustainable agriculture. To date, most of communication issues highlight role of extension officer rather than CBOs or the farmers meaning from top to bottom approach. It is realized that the flows of communication and the exchanges between different actors are extremely significant especially to understand the current state of agriculture and to facilitate the learning process. This underscores the need for dialogues and interactions between different actors and networks. Hence, this research will focus on CBOs because of the changing focus from extension officers to CBOs also changes the agricultural perspective. The purpose of this paper is to identify key actors that involved in an agricultural community-based organization (CBO). By identifying key actors, we can understand: 1) characteristic of a CBO; and 2) dissemination of agricultural knowledge – network. Therefore, a more sustainable agricultural practice can be embraced by many especially by conventional farmers.

Sign in / Sign up

Export Citation Format

Share Document