Does Nubility Indicate More Than High Reproductive Value? Nubile Primiparas’ Pregnancy Outcomes in Evolutionary Perspective

2021 ◽  
Vol 19 (3) ◽  
pp. 147470492110395
Author(s):  
William D. Lassek ◽  
Steven J. C. Gaulin

The idea that human males are most strongly attracted to traits that peak in women in the nubile age group raises the question of how well women in that age group contend with the potential hazards of a first pregnancy. Using data for 1.7 million first births from 1990 U.S. natality and mortality records, we compared outcomes for women with first births (primiparas) aged 16–20 years (when first births typically occur in forager and subsistence groups) with those aged 21–25 years. The younger primiparas had a much lower risk of potentially life-threatening complications of labor and delivery and, when evolutionarily novel risk factors were controlled, fetuses which were significantly more likely to survive despite lower birth weights. Thus, nubile primiparas were more likely to have a successful reproductive outcome defined in an evolutionarily relevant way (an infant of normal birth weight and gestation, surviving to one year, and delivered without a medically necessary cesarean delivery). This suggests that prior to the widespread availability of surgical deliveries, men who mated with women in the nubile age group would have reaped the benefit of having a reproductive partner more likely to have a successful first pregnancy.

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Herry Y. Tia ◽  
Lucky T. Kumaat ◽  
Diana Ch. Lalenoh

Abstract: The occurence of increased or decreased levels of hemoglobin of post-caesarean patients depends on the intake of nutrients during pregnancy, bleeding, and anemia. In case of massive and life-threatening bleeding during the caesarean section, blood transfusion has to be administered to revive the patient in critical condition. This study was aimed to obtain the patients’ levels of hemoglobin in either pre- and post-operative caesarean section without blood transfusion. This was a retrospective descriptive study using data of medical records at the Installation of Medical Record Department of Prof. Dr. R. D. Kandou Hospital Manado from September 2015 to August 2016. There were 32 patients in this study. The result showed that the mean values of pre-operative Hb was 12.4 g/dL and of post-operative Hb was 11.5 g/dL with a difference of 0.9 g/dL. Decreased levels of hemoglobin occured in 28 patients. It is discerned that the mean value of pre-operative Hb was 12.4 g/dL while of post-operative Hb was 11.3 g/dL with a difference of 1.1 g/dL. Furthermore, increased levels of hemoglobin occured in 4 patients, showing that the mean value of pre-operative Hb was 12.1 g/dLwhereas of post-operative Hb was 12.5 g/dL with a difference of 0.4 g/dL. Based on the characteristics of pregnant women, 23 cases (71.9%), were in the age group of 20-35 years; 18 cases (56.3%) of hemorrhage of 500-1000 ml; and 25 cases (78.1%) of 6-10 days length of hospitalization. Conclusion: In this study, there was increased as well as decreased hemoglobin levels in caesarean patients who were not administered blood transfusion during surgery.Keywords: hemoglobin, caesarean section, blood transfusion Abstrak: Terjadinya peningkatan maupun penurunan kadar hemoglobin pada operasi seksio sesarea tergantung pada asupan zat-zat nutrisi saat kehamilan, perdarahan, dan anemia. Jika terjadi perdarahan hebat selama operasi seksio sesarea berlangsung yang mengakibatkan penurunan kadar hemoglobin mendekati batasan untuk dilakukan transfusi darah, maka transfusi darah diberikan untuk menolong pasien pada kondisi kritis. Penelitian ini bertujuan untuk mengetahui gambaran kadar hemoglobin pasien pra dan pasca operasi seksio sesarea yang tidak mendapat transfusi darah. Jenis penelitian ialah deskriptif retrospektif menggunakan data rekam medik pasien seksio sesarea di Instalasi Rekam Medik RSUP Prof. Dr. R. D. Kandou Manado periode September 2015 sampai Agustus 2016. Hasil penelitian memperlihatkan 32 pasien yang memenuhi kriteria inklusi. Nilai mean kadar Hb pra 12,4 g/dL dan kadar Hb pasca 11,5 g/dL dengan selisih 0,9 g/dL. Penurunan kadar hemoglobin terdapat pada 28 pasien dengan nilai mean kadar Hb pra 12,4 g/dL dan kadar Hb pasca 11,3 g/dL (selisih 1,1 g/dL). Peningkatan kadar hemoglobin terdapat pada 4 pasien dengan nilai mean kadar Hb pra 12,1 g/dL dan kadar Hb pasca 12,5 g/dL (selisih 0,4 g/dL). Karakteristik ibu hamil didapatkan terbanyak kelompok usia 20-35 tahun berjumlah 23 kasus (71,9%), perdarahan 500-1000 cc berjumlah 18 kasus (56,3%), dan lama rawat inap 6-10 hari berjumlah 25 kasus (78,1%). Simpulan: Pada pasien operasi seksio sesarea yang tidak mendapat transfusi darah dapat terjadi penurunan maupun peningkatan kadar hemoglobin. Kata kunci: hemoglobin, seksio sesarea, transfusi darah


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Jenyfer P. Kakalang ◽  
Nurhayati Masloman ◽  
Jeanette I.Ch. Manoppo

Abstract: Febrile seizure usually occurs during increased body temperature (rectal temperature >380 C) caused by an extracranial process. Although febrile seizure is not a neurological disorder, it occurs most common among children. This study was aimed to obtain the profile of febrile seizure in children. This was a descriptive retrospective study. This study was conducted at the Department of Pediatrics Prof. Dr. R. D. Kandou Hospital from January 2014 to June 2016. The results showed that there were 150 children diagnosed as febrile seizure. The majority of them were as follows: age group of 1 - < 2 years old in 41 children (27.3%), males (50.7%), family history in 104 children (69.3%), respiratory tract infection as the cause of fever in 68 children (45.3%); complex febrile seizure in 91 children (60.7%); normal birth weight in 135 children (90%); normal nutritional status in 101 children (67.3%); and spontaneous delivery with head presentastion ins 127 children (84.7%). Conclusion: In this study, febrile seizure was most common among boys and diagnosed as complex febrile seizure.Keywords: febrile seizures, body temperature, extracranial, children Abstrak: Kejang demam ialah bangkitan kejang yang terjadi pada kenaikan suhu tubuh (suhu rektal >380C) yang disebabkan oleh suatu proses ekstrakranial. Walalupun kejang demam bukan merupakan suatu kelainan neurologis tetapi keadaan ini sering dijumpai pada anak. Penelitian ini bertujuan untuk mengetahui profil kejang demam pada anak. Jenis penelitian ialah deskriptif retrospektif untuk mengetahui profil kejang demam di Bagian Ilmu Kesehatan Anak RSUP Prof. Dr. R. D. Kandou periode Januari 2014 sampai Juni 2016. Hasil penelitian mendapatkan 150 anak yang didiagnosis kejang demam. Kejang demam paling sering ditemukan pada usia 1 - <2 tahun berjumlah 41 anak (27,3%); jenis kelamin laki-laki berjumlah 99 anak (66%); suhu badan >380C berjumlah 76 anak (50,7%); adanya riwayat keluarga 104 anak (69,3%); penyakit yang mendasari infeksi saluran pernafasan berjumlah 68 anak (45,3%); jenis kejang demam kompleks 91anak (60,7%); berat badan lahir normal 135 anak (90%); status gizi normal 101 anak (67,3%); riwayat jenis persalinan spontan LBK 127 anak (84,7%). Simpulan: Kejang demam paling sering terjadi pada anak laki-laki dan diagnosis jenis kejang demam kompleks. Kata kunci: kejang demam, suhu tubuh, ekstrakranial, anak


Author(s):  
Leah Gillion

Through numerous studies, scholars have come to view birth weight as having a lasting impact on educational outcomes. Normal birth weight is associated with greater educational attainment; however, much of the literature ignores the role of parental investment. Using data from the Fragile Families Child Well-Being Study, it was found that birth endowments alone do not produce varying levels of cognitive development, but these birth endowments do lead parents to make different choices for their children, choices that potentially exacerbate the educational divide. Children with normal birth weight receive more parental investment from birth to age 3 than children with abnormal birth weight. The increased parental investment from birth to age 3 directly increases cognitive scores and the role of parental investment on cognitive scores is amplified indirectly through birth weight. Parents may actually reinforce birth weight differences and, thus, it plays a role in the lingering cognitive gap exhibited later in life.


2016 ◽  
Vol 53 (5) ◽  
pp. 254
Author(s):  
Irene Melinda Louis ◽  
Adrian Umboh

Background Homocysteine is associated with endothelial damage and hypertension. Increased plasma homocysteine levels are often accompanied by cardiovascular impairment, including hypertension. Small for gestational age children have been found to have morbidity and mortality in cardiovascular diseases.Objective To assess for a possible association between homocysteine level and blood pressure in small for gestational age children.Methods This observational study was undertaken from December 2011 to April 2012 in Prof. Dr. R. D. Kandou Hospital, Manado, North Sulawesi, on children who were born small for gestational age in year 2004-2005. Data was analyzed by T-test to compare homocysteine levels in small for gestational age and normal birth weight children. Regression analysis and simple coefficient test were used to assess for an association between homocysteine levels and blood pressure in children who were small for gestational age at birth.Results The mean homocysteine level in small for gestational age children was significantly higher than that of normal birth weight children (P<0.001). We observed no correlation between homocysteine level and systolic blood pressure in the small for gestational age group (r=0.151, P=0.189). However, there was a weak correlation between homocysteine level and diastolic blood pressure in the small for gestational age group (r=0.237, P=0.049).Conclusion Children who were small for gestational age at birth have significantly higher mean homocysteine level than that of normal birth weight children. Higher homocysteine levels are associated with higher diastolic blood pressure in children who were small for gestational age at birth.


Author(s):  
Ramraj Meena ◽  
Purnima Pachori ◽  
Sandhya Chaudhary ◽  
Chandrakanta .

Background: Uric acid is the final product of the purine metabolism in humans. The two final reactions in its production which catalyze the conversion of hypoxanthine to xanthine and the latter to uric acid are catalyzed by the enzyme xanthine oxidoreductase. The role of uric acid in the progression of prediabetes to diabetes has been known. Serum uric acid has been shown to be associated with cardiovascular disease, hypertension, and chronic kidney disease. The present study was done to see the level of uric acid in preeclampsia and  healthy pregnant controls, to relate serum uric acid results to the severity of hypertension and its relation to fetomaternal outcome in patients attending OPD at RMC Ajmer.Methods: 100 cases of preeclampsia of age group between 20-40 year and gestational age ≥28 weeks and 100 normal healthy women with similar gestational age and age group were included in the study and maternal serum uric acid was estimated in both groups.Results: Mean serum uric acid levels in preeclampsia was 7.65±081 mg/dl and 3.21±072 mg/dl in control group. Perinatal complication was more in case group, 74 % were preterm compared to 11% in control group. Mean birth weight in study group was 2.07 kg, of which 24% babies were VLBW 52% were LBW, and 24% babies had normal birth weight, in control group mean birth weight was 2.82 kg. The difference was found to be statistically significant (p value 0.001). In the study group, the MSUA concentration is found higher in LBW and VLBW babies compared to normal birth weight babies.Conclusions: There is a positive correlation between SUA & severity of preeclampsia, and a significant adverse fetal outcome is observed with raised MSUA in preeclamptic patients.


1997 ◽  
Vol 87 (1) ◽  
pp. 17-22 ◽  
Author(s):  
E Sobel ◽  
MA Caselli ◽  
Z Velez

Sixty idiopathic toe walkers (age range 1 to 15 years) were evaluated to determine the natural history of toe-to-toe gait and the relationship between the range of ankle dorsiflexion and increasing age. The majority of toe walkers had a normal birth weight (average 7.06 pounds), walked on time (average 11.14 months), began toe walking immediately (87%), stood plantigrade (90%), were able to demonstrate a heel-toe gait (88%), and toe walked intermittently (68%). Forty-six percent of all toe walkers were found to have 0 degree or less of passive ankle dorsiflexion. Equinus toe walkers (mean dorsiflexion -5.2 degrees) had significantly less dorsiflexion than the remaining toe walkers (mean dorsiflexion 16.9 degrees; p &lt; 0.01). An average of 12 degrees of dorsiflexion was resent in the 1-to 2-year age group, which gradually diminished to -4 degrees in the 6- to 15-year age group. It appears that there may be a relationship between persistent toe walking and the development of ankle equinus in some children and therefore interventions should be considered to inhibit the toe walking progression.


2012 ◽  
Vol 19 (02) ◽  
pp. 145-149
Author(s):  
TASNIM TAHIRA ◽  
SUMERA TAHIR

Objective: To determine pregnancy outcome in patients presenting with heart disease during pregnancy and labour. Design:Descriptive study. Place & Duration of study: This study was conducted in Gynae Unit-I, Allied Hospital affiliated with Punjab Medical College,Faisalabad, during a period of 2 years from January 2009 to December 2010. Materials & Methods: This study included 74 patients whopresented with congenital or acquired heart disease during pregnancy or labour. Patients were evaluated for their cardiovascular status bycardiologist. Relevant investigations done to assess maternal and fetal condition. Results: 50 patients (67.6%) were in age group 20-25 years.Congenital heart disease was present in 8 (1.8%) patients while acquired heart disease was present in 66 patients (98.2%). 52 patients (70.3%)achieved term delivery, while 8 patients (10.8%) had spontaneous miscarriage and 14 patients (18.9%) had preterm delivery. 50 patients (76%)had live birth with normal birth weight, 12 patients (18%) had fetuses which were small for gestational age (SGA), 2 patients (3%) had stillbirthand 2 patients (3%) had early neonatal death due to prematurity. Conclusions: Heart disease in pregnancy is a high risk condition.Multidisciplinary approach should be adopted in the management of cardiac patient to achieve good obstetric and fetal outcome.


2017 ◽  
Vol 19 (2) ◽  
pp. 95
Author(s):  
Hetriana Leksananingsih ◽  
Slamet Iskandar ◽  
Tri Siswati

Background: Riskesdas in 2013 showed that Yogyakarta (DIY) had a prevalence of stunted new kid in school is less than the national average, which is 14.9% (MOH, 2013). Stunted or short, is a linear growth retardation has been widely used as an indicator to measure the nutritional status of individuals and community groups. Stunted can be influenced by several factors: birth weight, birth length match and genetic factors. Objective: To determine the weight, length of low birth weight and genetic factors as predictors of the occurrence of stunted on elementary school children. Methods: The study was a case control analytic. Research sites in SD Muhammadiyah Ngijon 1 Subdistrict Moyudan. The study was conducted in May and June 2015. The subjects were school children grade 1 to grade 5 the number of cases as many as 47 children and 94 control children. With the inclusion criteria of research subjects willing to become respondents, was present at the time of the study, they have a father and mother, and exclusion criteria have no data BB and PB birth, can not stand upright. The research variables are BBL, PBL, genetic factors and TB / U at this time. Data were analyzed by chi-square test and Odd Ratio (OR) calculation. Results: In case group as much as 91.5% of normal birth weight and length of 80.9% of normal birth weight, most of the height of a normal mother and father as many as 85.1%. In the control group as much as 78.7% of normal birth weight and 61.7% were born normal body length, height mostly normal mom and dad that 96.7% of women and 90.4% normal normal father. Statistical test result is no significant correlation between height mothers with stunted incidence in school children, and the results of chi-square test P = 0.026 with value Odd Ratio (OR) of 3.9 and a range of values from 1.091 to 14.214 Cl95%. Conclusion: High maternal body of mothers can be used as predictors of the occurrence of stunted school children and mothers with stunted nutritional status have 3.9 times the risk of having children with stunted nutritional status.


Author(s):  
Tewogbade Adeoye Adedeji ◽  
Simeon Adelani. Adebisi ◽  
Nife Olamide Adedeji ◽  
Olusola Akanni Jeje ◽  
Rotimi Samuel Owolabi

Background: Human immunodeficiency virus (HIV) infection impairs renal function, thereby affecting renal phosphate metabolism. Objectives: We prospectively estimated the prevalence of phosphate abnormalities (mild, moderate to life-threatening hypophosphataemia, and hyperphosphataemia) before initiating antiretroviral therapy (ART). Methods: A cross-sectional analysis was performed on 170 consecutive newly diagnosed ART-naïve, HIV-infected patients attending our HIV/AIDS clinics over a period of one year. Fifty (50) screened HIV-negative blood donors were used for comparison (controls). Blood and urine were collected simultaneously for phosphate and creatinine assay to estimate fractional phosphate excretion (FEPi %) and glomerular filtration rate (eGFR). Results: eGFR showed significant difference between patients’ and controls’ medians (47.89ml/min/1.73m2 versus 60ml/min/1.73m2, p <0.001); which denotes a moderate chronic kidney disease in the patients. Of the 170 patients, 78 (45.9%) had normal plasma phosphate (0.6-1.4 mmol/L); 85 (50%) had hyperphosphataemia. Grades 1, 2 and 3 hypophosphataemia was observed in 3 (1.8%), 3 (1.8%), and 1(0.5%) patient(s) respectively. None had grade 4 hypophosphataemia. Overall, the patients had significantly higher median of plasma phosphate than the controls, 1.4 mmol/L (IQR: 1.0 – 2.2) versus 1.1 mmol/L (IQR: 0.3 – 1.6), p <0.001, implying hyperphosphataemia in the patients; significantly lower median urine phosphate than the controls, 1.5 mmol/L (IQR: 0.7 -2.1) versus 8.4 mmol/L (IQR: 3.4 – 16), p <0.001), justifying the hyperphosphataemia is from phosphate retention; but a non-significantly lower median FEPi% than the controls, 0.96 % (IQR: 0.3 -2.2) versus 1.4% (IQR: 1.2 -1.6), p > 0.05. Predictors of FEPi% were age (Odds ratio, OR 0.9, p = 0.009); weight (OR 2.0, p < 0.001); CD4+ cells count predicted urine phosphate among males (p = 0.029). Conclusion: HIV infection likely induces renal insufficiency with reduced renal phosphate clearance. Thus, hyperphosphataemia is highly prevalent, and there is mild to moderate hypophosphataemia but its life-threatening form (grade 4) is rare among ART-naïve HIV patients.


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