Clinicopathological and prognostic significance and molecular mechanisms governing uveal melanoma
2020 ◽
Vol 12
◽
pp. 175883592091756
Keyword(s):
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Although UM and cutaneous melanoma are derived from melanocytes, UM differs clinically and biologically from its more common skin counterparts. More than half of primary UMs metastasize. However, there is currently no effective treatment for metastatic UM. Therefore, studying mutations related to the metastasis, growth, proliferation, and survival of UM can help researchers understand its pathogenesis and metastatic mechanism, thereby leading to a more effective treatment. In addition, we provide an overview of the recent basic and clinical studies to provide a strong foundation for developing novel anti-carcinogenesis targets for future interventions.
2020 ◽
Vol 26
(12)
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pp. 1251-1262
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2020 ◽
Vol 9
(1)
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2018 ◽
Vol 19
(10)
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pp. 3272
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2011 ◽
Vol 2011
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pp. 398-399
2021 ◽
Vol 40
(1)
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