Physiopathology of Dementia From the Perspective of Traditional Persian Medicine

The most common cognitive disorder that is disabling is dementia. During the medieval period, traditional Persian medicine was an outstanding source of medicine that was used as standard references in medical schools of in the West and Middle East. In ancient manuscripts of traditional Persian medicine, a condition has been introduced similar to dementi ( raoonat and homgh). In this article, by collecting materials of traditional medicine texts on dementia, we aim to provide theories for further studies on this topics, as there is an obvious difference between traditional Persian medicine and modern medicine with regard to dementia; however, since modern medicine has not found a suitable response to treatment for all diseases, reviewing traditional Persian medicine for finding better treatment strategies is wise. Use of all medical potentials approved by the World Health Organization beside classic medicine like traditional medicine and considering the availability and acceptability among people is recommended.

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Comparison of Leiomyoma of Modern Medicine and Traditional Persian Medicine

Journal of Evidence-Based Complementary & Alternative Medicine ◽

10.1177/2156587215595299 ◽

2015 ◽

Vol 21 (2) ◽

pp. 160-163 ◽

Cited By ~ 1

Author(s):

Mojgan Tansaz ◽

Haleh Tajadini

Keyword(s):

Treatment Strategies ◽

Modern Medicine ◽

Response To Treatment ◽

Medical Expenses ◽

Common Benign Tumor ◽

High Prevalence ◽

Persian Medicine ◽

Similar Disease ◽

Traditional Persian Medicine ◽

The One

Leiomyoma is the most common benign tumor of the pelvic that is associated with reproductive problems such as infertility, frequent abortions, and undesirable prenatal outcomes. High prevalence of leiomyoma and its relation with important gynecological complications, especially during reproductive ages, on the one hand, and high medical expenses and significant complications of common treatments, on the other, made us search traditional Persian medicine texts for a similar disease. In traditional Persian medicine, a condition has been introduced similar to leiomyoma ( Oram-e-rahem). In this article, by collecting materials from traditional medicine texts on leiomyoma, we aim to provide theories for further studies on this topic, as there is an obvious difference between traditional Persian medicine and modern medicine with regard to leiomyoma. When modern medicine has not found a suitable response to treatment, reviewing of traditional Persian medicine for finding better treatment strategies is wise.

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Perceptions towards the practice of Andean traditional medicine and the challenges of its integration with modern medicine. Case Cuenca, Ecuador

MASKANA ◽

10.18537/mskn.12.01.03 ◽

2021 ◽

Vol 12 (1) ◽

pp. 26-34

Author(s):

Adriana Orellana-Paucar ◽

Valeria Quinche-Guillén ◽

Danilo Garzón-López ◽

Rafaella Ansaloni ◽

Geovanny Barrera-Luna ◽

...

Keyword(s):

Traditional Medicine ◽

National Health System ◽

Modern Medicine ◽

World Health ◽

Main Theme ◽

Snowball Sampling ◽

Structured Interviews ◽

The World ◽

Health Organization ◽

Phenomenological Design

There is currently a resurgent interest in traditional medicine. The World Health Organization suggested applying strategies for its proper integration into the National Health System. This study seeks to know and understand the opportunities and challenges of the practice of Andean traditional medicine (ATM) in Cuenca (Ecuador) within the context of a possible integration with modern medicine (MM) from the perspective of healers, physicians, and users. The study is qualitative and has a phenomenological design. Convenience and snowball sampling was applied to select participants for focus groups, individual semi-structured interviews, and individual non-participatory observations. The information was qualitatively processed, and the findings categorized into 2 major themes (a. Opportunities in the practice of ATM, and b. Challenges in the potential integration of ATM in MM) and 14 associated subthemes, respectively 6 in the first main theme and 8 in the second main theme. Participants characterized the strengths and weaknesses in integrating Andean traditional medicine with modern medicine. Findings suggest that an appropriate integration of ATM with MM request a government regulatory framework encouraging the protection of ancestral wisdom and biodiversity, a safe and rational application of joint therapies, and research development in the area.

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Medicinal Chemistry of Alternative Therapeutics: Novelty and Hopes with Genus Ammannia

Current Topics in Medicinal Chemistry ◽

10.2174/1568026619666190412101047 ◽

2019 ◽

Vol 19 (10) ◽

pp. 784-794 ◽

Cited By ~ 3

Author(s):

Harish C. Upadhyay

Keyword(s):

Traditional Medicine ◽

Biological Activities ◽

World Health ◽

Biologically Relevant ◽

Traditional Medicines ◽

Drug Molecules ◽

Health Organization ◽

Tract Infections ◽

Pharmacologically Active ◽

Herbal Formulations

The plants have formed the basis of folklore remedy since the beginning of human civilization. The cumulative human endeavor and experience over a period of thousands of years developed into well to organize traditional medicine systems viz. Ayurvedic, Unani, Chinese amongst others. Across the world, traditional medicine is either the mainstay of health care or serves as a complement to modern drugs. In view of worldwide use of traditional medicines, World Health Organization launched ‘WHO-Traditional Medicine Strategy 2014-2023’ for the development of strong policies regarding knowledge-base, safety, quality-control and effectiveness of traditional/alternative therapeutics for national health systems. Besides their use in traditional medicine, plants have always been a good source of modern drug/pharmacologically active molecules. More than half of the modern pharmaceuticals are either plant isolates or their derivatives. The plant-based drugs are not only effective, but have better compatibility with human biological systems because of more biologically relevant chemistry, hence lesser side effects. Some of the species of genus Ammannia (Lythraceae) have been reported for their magical medicinal values. Many herbal formulations containing Ammannia spp. have been patented for treatment of serious diseases/disorders like cancer, spinal disease, human female infertility, chronic tonsillitis, pelvic inflammatory disease, treatment of bladder stones, urinary tract infections, dermatitis etc. The uses of Ammannia spp. in traditional medicine have been further verified by the biological activities of their extracts as well as isolation of bioactive phytomolecules. The current review provides details about Ammannia spp.; its use in folklore remedy, herbal formulations, biological activities of extracts, isolation of bioactive phytomolecules and SAR study of semi-synthetic derivatives to analyze the possibility of new drug molecules of plant origin.

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Probiotics: A Promising Candidate for Management of Colorectal Cancer

Cancers ◽

10.3390/cancers13133178 ◽

2021 ◽

Vol 13 (13) ◽

pp. 3178

Author(s):

Ashutosh Tripathy ◽

Jayalaxmi Dash ◽

Sudhakar Kancharla ◽

Prachetha Kolli ◽

Deviyani Mahajan ◽

...

Keyword(s):

Colorectal Cancer ◽

Treatment Strategies ◽

Intestinal Barrier ◽

World Health ◽

Intestinal Barrier Function ◽

Cancer Type ◽

Prevention Therapy ◽

Long Time ◽

Health Organization ◽

Cancerous Cells

Colorectal cancer (CRC) is the World’s third most frequently diagnosed cancer type. It accounted for about 9.4% mortality out of the total incidences of cancer in the year 2020. According to estimated facts by World Health Organization (WHO), by 2030, 27 million new CRC cases, 17 million deaths, and around 75 million people living with the disease will appear. The facts and evidence that establish a link between the intestinal microflora and the occurrence of CRC are quite intuitive. Current shortcomings of chemo- and radiotherapies and the unavailability of appropriate treatment strategies for CRC are becoming the driving force to search for an alternative approach for the prevention, therapy, and management of CRC. Probiotics have been used for a long time due to their beneficial health effects, and now, it has become a popular candidate for the preventive and therapeutic treatment of CRC. The probiotics adopt different strategies such as the improvement of the intestinal barrier function, balancing of natural gut microflora, secretion of anticancer compounds, and degradation of carcinogenic compounds, which are useful in the prophylactic treatment of CRC. The pro-apoptotic ability of probiotics against cancerous cells makes them a potential therapeutic candidate against cancer diseases. Moreover, the immunomodulatory properties of probiotics have created interest among researchers to explore the therapeutic strategy by activating the immune system against cancerous cells. The present review discusses in detail different strategies and mechanisms of probiotics towards the prevention and treatment of CRC.

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A pilot study of clonazepam versus psychodynamic group therapy plus clonazepam in the treatment of generalized social anxiety disorder

European Psychiatry ◽

10.1016/j.eurpsy.2008.05.004 ◽

2008 ◽

Vol 23 (8) ◽

pp. 567-574 ◽

Cited By ~ 27

Author(s):

Daniela Z. Knijnik ◽

Carlos Blanco ◽

Giovanni Abrahão Salum ◽

Carolina U. Moraes ◽

Clarissa Mombach ◽

...

Keyword(s):

Anxiety Disorder ◽

Social Anxiety ◽

Group Therapy ◽

Social Anxiety Disorder ◽

Treatment Strategies ◽

World Health ◽

Global Functioning ◽

Psychodynamic Group Therapy ◽

Efficacy Measures ◽

Health Organization

AbstractBackgroundBoth psychodynamic group therapy (PGT) and clonazepam are used as treatment strategies in reducing symptoms of generalized social anxiety disorder (GSAD). However, many individuals remain symptomatic after treatment with PGT or clonazepam.MethodFifty-eight adult outpatients with a diagnosis of GSAD according to DSM-IV were randomized to 12 weeks PGT plus clonazepam or clonazepam. The Clinical Global Impression-Improvement (CGI-I) Scale was the primary efficacy measure. Secondary efficacy measures included the Liebowitz Social Anxiety Scale (LSAS) total score, the World Health Organization Instrument to Assess Quality of Life—Brief (WHOQOL-Bref) Scale and the Beck Depression Inventory (BDI).ResultsCGI-I data from 57 patients (intent-to-treat population) showed that patients who received PGT plus clonazepam presented significantly greater improvement than those who received clonazepam (P = 0.033). There were no significant differences between the two groups in the secondary efficacy measures.ConclusionsOur study suggests that the combination of PGT with clonazepam may be a promising strategy for the treatment of GSAD, regarding gains in the global functioning. However the present study failed to detect more specific changes in social anxiety symptomatology between the two groups.

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An Investigation on the Properties of Zingiber officinale Rose and Its Application in Nutrition and Medicine Based on Scientific and Islamic Texts

Tabari Biomedical Student Research Journal ◽

10.18502/tbsrj.v3i4.7791 ◽

2021 ◽

Author(s):

Hamed Fathi ◽

Fatemeh Faraji ◽

Niusha Esmaealzadeh ◽

Shahram Eslami ◽

Mohammad Bagher Mohammadi Laeeni

Keyword(s):

Clinical Studies ◽

Web Of Science ◽

Zingiber Officinale ◽

Modern Medicine ◽

Pharmacological Properties ◽

Laboratory Studies ◽

Scientific Databases ◽

Positive Effects ◽

Persian Medicine ◽

Traditional Persian Medicine

Introduction: Zingiber officinale Rose (ginger) has been used for many purposes in traditional medicine since 2500 years ago. This study intends to introduce the ginger plant, some of their applications in the field of human health in traditional and modern medicine, and their conformity with Islamic and Quranic findings. Material and Methods: Administrative and therapeutic information of ginger plant has been searched in related and valid books, scientific databases including Web of Science, PubMed, SID, Google Scholar, and Scopus. Ginger keyword has been searched in the Quran and hadiths and its medicinal and pharmacological properties; also in traditional Persian medicine and laboratory studies, the day, was collected from published articles. In order to confirm the obtained information, it was matched with Quranic and narration versions, and the obtained information was analyzed, compiled, and presented. Results: Avicenna has mentioned the positive effects of ginger in his Canon of Medicine. The Food and Drug Administration of the Ministry of Health in Iran has also introduced ginger as a dietary supplement. Ginger is one of those plants which name is mentioned in the Quran, in verse 17 of Surah Al-Insan. In narrations and quoting scientists as well as in modern medicine and articles, the effects and application of this plant in the field of medicine and nutrition have been mentioned. Conclusion: The results have shown that the use of ginger in nutrition as a spice or supplement and in Persian medicine as a medicament has a scientific and practical basis, and studies on this issue are confirmed both in science and Islam. Findings obtained from laboratory and clinical studies can also be effective in the proper use and preparation of appropriate medicinal forms of this plant.

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Factors Affecting Tendency and Adherence to Traditional Persian Medicine: A Qualitative Study

Jundishapur Journal of Natural Pharmaceutical Products ◽

10.5812/jjnpp.107933 ◽

2021 ◽

Vol In Press (In Press) ◽

Author(s):

Mansoureh Sabbagh-Bani-Azad ◽

Roja Rahimi ◽

Abbas Kebriaeezadeh ◽

Mohammad Mahdi Zolfagharzadeh ◽

Akbar Abdollahiasl

Keyword(s):

Qualitative Study ◽

Healthcare Providers ◽

Modern Medicine ◽

Saturation Point ◽

Factors Affecting ◽

Medical Discipline ◽

Persian Medicine ◽

Traditional Persian Medicine ◽

Based Medicine ◽

Depth Interviews

Background: Adherence to medications is crucial for them to be effective. Traditional Persian Medicine (TPM) is an ancient medical discipline originated from old Persia and is currently used along with modern medicine in Iran. Evaluating the factors affecting adherence to TPM can have far-reaching implications for policymakers to make informed decisions. Objectives: This qualitative study investigates the factors affecting tendency and adherence to TPM among Iranians. Methods: We collected data from stakeholders in TPM using a focus group involving 13 participants and by conducting four in-depth interviews. The saturation point was reached at the 4th interview. We recorded all the interviews and then transcribed them verbatim for thematic content analysis. Results: We obtained 297 codes and 29 sub-themes for the factors affecting adherence to TPM, including the factors affecting compliance and tendency. Then we extracted the main themes. People’s beliefs, the inherent characteristics of traditional medicine and its status quo, attempts to bring about positive changes to TPM, and the problems facing the modern health system were the main factors affecting adherence to TPM. Conclusions: Despite many strenuous efforts in Iran to study TPM along with the lines of evidence-based medicine, policymaking, financing, patients’ and healthcare providers’ education, popular beliefs, and administrative transparency are needed to be addressed more adequately to promote adherence to TPM and help build integrative medicine in Iran’s healthcare system.

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Management of Breast Milk Oversupply in Traditional Persian Medicine

Journal of Evidence-Based Complementary & Alternative Medicine ◽

10.1177/2156587217722474 ◽

2017 ◽

Vol 22 (4) ◽

pp. 1044-1050 ◽

Cited By ~ 1

Author(s):

Marya Kabiri ◽

Mohammad Kamalinejad ◽

Farnaz Sohrabvand ◽

Soodabeh Bioos ◽

Mohammad Babaeian

Keyword(s):

Breast Milk ◽

Current Literature ◽

Modern Medicine ◽

Current Medical ◽

Medical Resources ◽

Persian Medicine ◽

Natural Remedies ◽

Traditional Persian Medicine ◽

Medical Concepts

Comprehensive explanation about milk oversupply is not available in the current literature because few studies have been done on this topic. In traditional Persian medicine, milk oversupply and its management have been described. The aim of this study was to investigate milk oversupply from the perspective of medieval Persian practitioners. In this study, some main medical resources of traditional Persian medicine such as Al-Havi and the Canon of Medicine were studied to extract valuable information about milk oversupply. Etiology of milk overproduction according to traditional Persian medicine is based on humors theory and cannot be easily compared with current medical concepts. Diet modifications and natural remedies have been applied for managing this condition but the majority of traditional Persian medicine interventions for reducing milk oversupply have not been scientifically investigated in modern medicine. The knowledge of milk oversupply in traditional Persian medicine may be helpful to conduct further related studies.

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Investigation of the physicochemical and pharmacognostical properties of Anzaroot (The manna of Astragalus sarcocola Dymock.) according to the World Health Organization

Medical Journal of Tabriz University of Medical Sciences and Health Services ◽

10.34172/mj.2020.080 ◽

2020 ◽

Vol 42 (5) ◽

pp. 564-571

Author(s):

Hadi Esmaeeli ◽

Ali Davoodi ◽

Masoud Azadbakht ◽

Mohammad Azadbakht

Keyword(s):

Traditional Medicine ◽

World Health Organization ◽

Pharmaceutical Products ◽

Water Soluble ◽

World Health ◽

Flavonoid Content ◽

Therapeutic Properties ◽

The Common ◽

Health Organization ◽

Scientific Name

Background: Anzaroot is a manna produced from Astragalus sarcocola Dymock (Family Leguminosae) that is widely distributed in Fars, Kerman, Baluchestan and Hormozgan in Iran. Since the study of the physicochemical properties and quality control (QC) of herbal materials results in the validation and standardization for clinical uses, in accordance with World Health Organization (WHO) guidelines, it is necessary to carry out for Anzaroot which has indication in traditional medicine. Methods: Anzaroot was identified and determinated scientific name by a systematic specialist after purchasing from Niak pharmaceutical co. in gorgan. Physicochemical and pharmacognostical properties of Anzaroot have been determinated According to the WHO guidlines. Results: Anzaroot is a very bitter, crisp and fragile manna and non-stick in dry state, which is seen as separate binary grains under the microscope. The moisture content, foreign matter, sucrose content, total ash and water-soluble ash were reported 5.25 ± 0.2, 2.8 ± 0.2, 12.09 ± 0.04, 9.8 ± 0.5 and 2.9±0.15, respectively. It has significant foaming index, 72% Solublity in water and less than 50% in 96% ethanol and not swelling index. The levels of lead, mercury and cadmium were 0.0006, 0.0002 and 0.0007 ppm and total flavonoid content was reported 18.61 μg/ml with respect to standard Quercetin at 415 nm. Conclusion: This study can be a novel idea for the discovery or development of pharmaceutical products based on Anzaroot of Iran and its diverse therapeutic properties, such as the common cold, contusion, and bone fracture in traditional medicine.

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