scholarly journals Effects of Proprioceptive Neuromuscular Facilitation and Mulligan Concepts on the Pain, Functional Level and Quality of Life on Subacromial Impingement Syndrome

2014 ◽  
Vol 2 (11_suppl3) ◽  
pp. 2325967114S0014 ◽  
Author(s):  
Sinem Karakuş ◽  
Nihal Gelecek ◽  
Sevgi Sevi Yeşilyaprak
Keyword(s):  
Quality Of Life ◽  
Physical Therapy ◽  
Subacromial Impingement Syndrome ◽  
Functional Level ◽  
Vas Score ◽  
Group I ◽  
Sf 36 ◽  
Mulligan Concept ◽  
Shoulder Score

Objectives: The purpose of the study was to investigate the effects of Proprioceptif Neuromuscular Facilitation (PNF) and Mulligan concepts on the pain, functional level and quality of life in the patients with subacromial impingement syndrome (SIS). Methods: This study was carried out on 40 patients (26 females, 14 males), mean age 50,3±1,13 years, who had been diagnosed as SIS admitted to the physical therapy and rehabilitation clinic. Before the beginning measurements all the patients were separated to 2 groups according to simple random table. Standard physical therapy and PNF were given to the Group I (n=20); and Standard physical therapy and Mulligan Concept were added to the Group II (n=20). In the evaluation process the demographic data of the patients, pain severity (VAS), functional level (Constant shoulder score) and quality of life (SF-36) measurement were done. The measurements were done before treatment, after treatment and 3 month later. Results: Before treatment, VAS score, Constant shoulder score and quality of life scores were similar and there were no statistically differences between two groups (p>0.05). After treatment and 3 month later, VAS score decreased, Constant Shoulder score increased in both groups(p<0.05). For Group I, SF-36 physical component and mental component scores increased after treatment (p<0.05), but mental component score was not change in Group II (p>0.05). However, there were no statistically significant differences in the VAS score, Constant Shoulder Score, and mental health score between Groups I and II after treatment and 3 month (p > 0.05). Conclusion: The results of our study suggested that PNF and Mulligan concept could influence positively on shoulder pain, functional level of upper extremity and quality of life in patients with SIS and these effects were similar.

scholarly journals Effect of a physical therapy protocol on the health related quality of life of patients with temporomandibular disorder

2016 ◽  
Vol 29 (3) ◽  
pp. 507-514
Author(s):  
Maíra de Oliveira Viana ◽  
Natália Bitar da Cunha Olegario ◽  
Mariana de Oliveira Viana ◽  
Guilherme Pinheiro Ferreira da Silva ◽  
Jair Licio Ferreira Santos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Therapy ◽  
Dental Treatment ◽  
Temporomandibular Disorder ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
School Of Dentistry ◽  
Therapy Protocol

Abstract Introduction: Temporomandibular disorders (TMD) comprise a group of diseases that affect not only the temporomandibular joint, but also different areas extrinsic to the joints. Quality of life has been the subject of numerous studies in the Health area, especially aimed at people with chronic diseases, such as TMD. Objective: To evaluate effects of a physical therapy protocol on the quality of life of patients with temporomandibular disorder. Methods: Blinded, prospective, clinical trial, with 60 patients of both genders, aged between 18 and 70 years with TMD diagnosis attended in the clinic of Ribeirão Preto School of Dentistry. The patients were divided into two groups, with one group, in addition to dental treatment, receiving a physical therapy protocol and the other group dental treatment only, for 5 weeks. The measurement of quality of life was obtained through the generic SF-36 questionnaire, at the beginning and end of the proposed protocol. Results: The patients to whom the physical therapy protocol was applied associated with dental care presented increased scores in all the domains of the questionnaire. In the group that received only dental treatment, improvements were only found in the domain related to pain. Conclusion: The application of a physical therapy protocol was able to improve the quality of life of patients with temporomandibular disorder.

scholarly journals Comparitive evaluation of different concentrations of alcohol in ultrasound guided coeliac plexus neurolysis for pain relief in upper abdominal malignancies

2021 ◽  
Vol 8 (4) ◽  
pp. 492-500
Author(s):  
Manish Kumar Singh ◽  
Pragya Verma ◽  
Sarita Singh ◽  
Gyan P Singh ◽  
Hemlata Verma
Keyword(s):  
Quality Of Life ◽  
Morphine Consumption ◽  
Rescue Analgesia ◽  
Vas Score ◽  
Group I ◽  
Significant Difference ◽  
The Mean ◽  
Group Ii ◽  
Upper Abdominal

Patients suffering from advanced upper abdominal malignancies have pain as predominant symptom affects their quality of life and survival. USG guided coeliac plexus neurolysis become benevolence in these patients on part of their pain management and quality of life improvement. To compare the efficacy of USG guided coeliac plexus neurolysis for pain relief in upper abdominal malignancies by using different concentration of alcohol (50% vs 75%).This Prospective, comparative, randomised double blinded study was conducted during Sep 2019 – Aug 2020 at our tertiary care centre. Total 60 cases were taken as per following inclusion and exclusion criteria and randomly divided into 2 groups i.e. 30 each group, we compare Visual Analogue Scale (VAS) score, quality of life (QOL) and need of rescue analgesia profile between the groups to know the efficacy of USG guided coeliac plexus block. In our study, we observed that the baseline mean VAS score in group I was 8.26±0.78 while in group II was 8.03±0.76. No significant difference was found in mean VAS score at this time between the groups (p=0.24). The baseline mean QOL score in group-I was 77.46±3.40 while for the cases of group II the mean QOL score was 77.36±3.33. No significant difference was found in mean QOL score at baseline between the groups (p=0.90). The baseline mean morphine consumption in group-I was 113.33±39.24 mg while for the cases of group-II the mean morphine consumption was 120.33±38.37mg. No significant difference was found in mean morphine consumption at this time between the groups (p=0.48).Both groups having 50% alcohol and 75% alcohol decreases the VAS score from baseline in patients having upper abdominal malignancies along with QOL and dosages of rescue analgesia whereas no significant difference in VAS score in patients of both groups.

scholarly journals Quality of Life of Patients with Stable Coronary Artery Disease Combined with Non-Alcoholic Fatty Liver Disease

2016 ◽  
Vol 23 (4) ◽  
pp. 2016416
Author(s):  
Iryna Vakalyuk ◽  
Nataliya Virstyuk ◽  
Vitaliy Petryna
Keyword(s):  
Quality Of Life ◽  
Liver Disease ◽  
Stable Coronary Artery Disease ◽  
Control Group ◽  
Alcoholic Fatty Liver ◽  
Group I ◽  
Sf 36 ◽  
Artery Disease ◽  
Alcoholic Fatty Liver Disease

Quality of life assessment is an integral part of a comprehensive treatment in modern medical practice. Analysis of quality of life of patients with comorbidities is an interesting and poorly understood issue. The objective of the research was to evaluate the quality of life of patients with postinfarction cardiosclerosis depending on the presence and progression of non-alcoholic fatty liver disease (NAFLD).Material and methods. The research included 300 patients with stable coronary artery disease (CAD). They included 160 patients without NAFLD (Group I) and 140 patients with NAFLD (Group II). 89 patients of Group II suffered from non-alcoholic liver disease (NALD) and 51 patients from non-alcoholic steatohepatitis (NASH). The control group consisted of 20 apparently healthy individuals. SF-36 and MacNew questionnaires were used to assess the quality of life. Results. The overall estimate according to SF-36 questionnaire detected a significant decrease in the patient’s quality of life due to their low physical activity, mental ill-being, limitation of daily activities, significant effect of pain and low assessment of their health. Decrease in the quality of life was clearly dependent on NAFLD stage and was the lowest in case of NASH. The overall estimate of quality of life according to MacNew questionnaire was 1.5 times lower in patients of Group I compared to the control group, decreased almost by 1.4 times in patients with NALD compared to Group I and was 1.5 times lower in case of NASH compared to the patients with NALD (p<0.05). Conclusions. Patients with stable CAD combined with NAFLD were characterized by decrease in quality of life due to its physical, psycho-emotional and social components. Quality of life of patients with postinfarction cardiosclerosis depended on NAFLD progression and was the lowest in case of NASH.

scholarly journals Effect of targeted physiotherapy on the quality of life of patients with epilepsy of unknown etiology – a pilot study

2021 ◽  
Vol 24 (2) ◽  
Author(s):  
Elżbieta Szczygieł-Pilut ◽  
Elżbieta Mirek ◽  
Magdalena Filip ◽  
Daniel Pilut ◽  
Szymon Pasiut ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Therapy ◽  
Unknown Etiology ◽  
Study Group ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Sf 36 ◽  
Generalized Epilepsy ◽  
Patients With Epilepsy

Introduction: Epilepsy is one of the most common diseases of the central nervous system. According to the World Health Organization, it accounts for 1% of the global burden of disease worldwide. Pharmacotherapy remains the primary therapeutic tool in this disease. However, more and more emphasis is placed on approaching this group of patients in an interdisciplinary manner, taking their various needs into account: social, professional, economic or psychological. Attention is also paid to the positive impact of physical activity on the quality of life of patients with epilepsy. The patients with diagnosed epilepsy often complain of a feeling of instability not reflected in standard neurological examination. Early detection of postural control disorders is possible using an objective research tool which is the modified CTSIB test (Clinical Test of Sensory Interaction and Balance). Aim of the study: The aim of the study was to assess the influence of targeted physical therapy on the quality of life among patients with diagnosed epilepsy of unknown etiology using the SF-36 quality of life questionnaire. Materials and methods: The study included 11 professionally active adults with diagnosed generalized epilepsy of unknown etiology, treated at the Department or Outpatient Clinic of Neurology at John Paul II Specialist Hospital in Kraków. Finally, out of the 11 recruited patients (5 women and 6 men), 1 patient was excluded from the study due to a history of craniocerebral trauma. Patients were examined 3 times every month using EEG and the SF-36 quality of life questionnaire. Additionally, between the 2nd and the 3rd month of the pilot study, the study group underwent physical therapy focused on balance disorders using the Biodex SD stabilometric platform. Results: Overall, the quality of life index measured using the SF-36 quality of life questionnaire in the study group improved after the completion of targeted physical therapy. Conclusions: 1. Generalized epilepsy of unknown etiology results in a significant deterioration in the quality of life of patients, which may also be accompanied by disorders of postural control. 2 A targeted program of physiotherapy in the treatment of patients with generalized epilepsy of unknown etiology may has a positive effect on their quality of life. null

EFFECTS OF BIOLOGICAL THERAPY ON QUALITY OF LIFE AND PSYCHOEMOTIONAL STATUS OF PATIENTS WITH ULCERATIVE COLITIS

2021 ◽  
Vol 74 (10) ◽  
pp. 2610-2613
Author(s):  
Antonina V. Varvarynets
Keyword(s):  
Quality Of Life ◽  
Ulcerative Colitis ◽  
Biological Therapy ◽  
Old Patients ◽  
Group Iii ◽  
Group I ◽  
Sf 36 ◽  
Nonspecific Ulcerative Colitis ◽  
Social Introversion

The aim: To compare the effects of tofacitinib, adalimumab and budesonide on the quality of life and psychoemotional status of patients with moderate UC. Materials and methods: The study included 104 patients with moderately severe UC aged between 18 and 75 years old. Patients were divided into 3 groups. Group I consisted of patients with UC treated with budesonide 9 mg 1 g / d (BUD; n = 34). Group II – of patients receiving adalimumab at an initial dose of 160 mg and 80 mg at week 2, followed by maintenance dose of 40 mg weekly (ADA; n = 38) and group III, who received tofacitinib 10 mg 2p / d (TOF; n = 32). Evaluation of quality of life and psycho-emotional status of patients was performed using IBDQ, SF-36 and MMRI questionnaires. Results: According to the IBDQ-questionnaire, all groups after treatment had a statistically significant increase in their results: BUD (from 146,44 ± 2,23 to 151,36 ± 2,40), ADA (from 144,28 ± 3,10 to 172,36 ± 3,12), TOF (from 149,22 ± 2, 86 to 184.36 ± 2.88), respectively, p <0.05. Also, after treatment statistically significant changes were seen in patients of all groups in regards to the psychological and physical components of the SF-36 scale. Analysis of the personality profile using MMRI of all groups of patients showed a change in scales 2 (depression), 3 (hysteria), 5 (tenderness-femininity), 6 (paranoia) and 0 (social introversion), which significantly improved in the ADA and TOF groups. Conclusions: Tofacitinib and adalimumab in patients with nonspecific ulcerative colitis of moderate severity had a better effect on quality of life and psychoemotional status compared with budesonide treatment.

scholarly journals Compressive Stockings After Hindfoot and Ankle Surgery

2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0023
Author(s):  
Florian Grubhofer ◽  
Stephan Wirth
Keyword(s):  
Quality Of Life ◽  
Clinical Results ◽  
Control Group ◽  
End Points ◽  
High Compliance ◽  
Group I ◽  
Sf 36 ◽  
Ankle Surgery ◽  
Group Ii

Category: Hindfoot Introduction/Purpose: Swelling and pain are common after foot and ankle procedures. We hypothesized that compressive stockings (CS) treatment after hindfoot surgery would positively influence patient outcomes. Methods: We undertook this randomized controlled trial in 87 consecutive patients to analyze the clinical effect of CS after hindfoot and ankle surgery and evaluate CS-wearing compliance using sensors that were implanted into CS. Ankle swelling, pain status, quality of life (SF-36 score), and the American Orthopaedic Foot & Ankle Score (AOFAS) were set as the primary end points. The CS wearing time in hours and percentage were investigated as the secondary end points. All participants with CS (group I) were informed about the implanted sensor after the CS were taken off. A subgroup analysis of group I was performed to detect differences between patients with high vs low compliance. Results: At 12 weeks, the results of ankle swelling (mean 234 mm in group I and 232 mm in group II), pain in the visual analog scale (1.7 group I vs 1.9 in group II), the SF-36 score (38 points in group I vs 30 points in group II), and the AOFAS score (a mean of 76 points in both groups) showed no statistical differences between the 2 groups. The mean wearing time was 136 (range, 0-470) hours, which corresponds to a compliance rate of 65%. Sixteen participants had high compliance (>80%, >170 hours), and 21 patients had low or noncompliance. The clinical results of patients with high wearing compliance were not significantly better compared to the results of patients with low compliance. Conclusion: CS therapy after ankle and hindfoot surgery was associated with a low wearing compliance and did not influence ankle swelling, function, pain, and the quality of life compared to the control group. Furthermore, the clinical results of patients with high compliance were not better compared to the results of patients with low or noncompliance wearing behavior.

scholarly journals Therapeutic Effects of Intra-Articular Botulinum Neurotoxin Versus Physical Therapy in Knee Osteoarthritis

2021 ◽  
Vol 11 (3) ◽  
Author(s):  
Zahra Rezasoltani ◽  
Afsaneh Dadarkhah ◽  
Seyed Morteza Tabatabaee ◽  
Fateme Abdorrazaghi ◽  
Morteza Kazempour Mofrad ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Therapy ◽  
Knee Osteoarthritis ◽  
Botulinum Neurotoxin ◽  
Demographic Data ◽  
Therapeutic Effects ◽  
Vas Score ◽  
Chronic Knee Pain ◽  
Significant Difference

Background: Knee osteoarthritis (KOA) is the most common cause of chronic knee pain, and disability and different modalities have been used to improve pain and function. Botulinum toxin intra-articular injection is proposed to manage resistant joint pains. Objectives: This study was carried out to compare therapeutic effects of intra-articular botulinum neurotoxin (BTX) versus physical therapy (PT) in KOA. Methods: In this single-blind randomized clinical trial, patients with KOA attending to Imam-Reza Hospital, Tehran, Iran, from June 2018 to March 2019 were enrolled. Patients who met the inclusion criteria were randomly divided into BTX receiving a single intra-articular dose of 100 units (250 units from disport brand) and PT groups. The study was described for patients, and informed consent forms were received. For assessment of the pain and related severity, the VAS score and KOOS scales were used. Post-intervention assessment was done 1, 3, and 6 months after the intervention. The level of significance was set at α = 0.05. All data analyses were performed with SPSS version 26 for windows. Results: In this study, 50 patients were randomly divided into BTX and PT groups. All patients completed the study, and there was no loss to follow-up. There was no significant difference between demographic data of the two groups, including age and BMI. The VAS score was similar in the two groups at the beginning. KOOS subscales were not significantly different, but the quality of life was better in the BTX than the PT group (86.2 ± 15 vs. 72.1 ± 11.5, P < 0.001). One month after the intervention, all KOOS subscales were improved in the BTX group in comparison to the PT group (P < 0.001). This difference was statistically significant in the 3rd (P < 0.001 in all comparisons except Sport/Rec subscale in which P = 0.02) and 6th months (P < 0.001) after the intervention, and the improvement in all KOOS subscales and VAS score were higher in the BTX group than the PT group. The trend of KOOS subscales and VAS score was improved over time in the BTX (P < 0.001 in all tests), but the PT group showed no improvement (P > 0.05) except for Sport/Rec and VAS score (P < 0.001). Conclusions: Totally, it is concluded that the use of BTX can reduce pain and improve the function and quality of life in patients with KOA.

scholarly journals Effect of physical therapy on posture and quality of life in subject with parkinson\'s disease

2021 ◽  
Vol 4 (3) ◽  
pp. 104-115
Author(s):  
Nensi Vaibhav Gandhi ◽  
Rachana Rabari ◽  
Kinjal Rathve ◽  
Shreya Patel
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Physical Therapy ◽  
Mean Value ◽  
Body Posture ◽  
Control Group ◽  
P Value ◽  
Sf 36 ◽  
And Control

It is a chronic progressive degenerative disorder of extra pyramidal system caused by loss of dopaminergic neurons in the substantia nigra and characterized by tremors, rigidity, bradykinesia, and disturbance of gait and posture.The neuropsychiatric symptoms of PD may include depression, psychosis, apathy, impulse control disorders that are linked with the poor quality of life due to the progression of disease. Despite, cognitive impairment in PD is of great significance in terms of therapeutic approaches in order to deal with motor deficits of disorder. Multiple studies have revealed that exercise has been proven to be effective for the maintenance of health and well-being in Parkinson’s. More importantly it is shown to play a significant role in addressing secondary prevention based on strength, flexibility, functional independence as well as gait and balance respectively.To evaluate the effect of physical therapy on posture and quality of life in subject with Parkinson’s diseaseSource of Data: Radha multispecielist Hospital, Shreeji Hospital, Parul Shevashram,Venus.Sampaling Method: Convenience,samplingSample Size: 30 subject were included (15 in) each groupsSelection f Sample: convenientStudy Design: experimentalStudy Duration: 30 min/day/7 week(1)Patient with 50 to 75 years of age (2)Participants patient diagnosed with Parkinson’s diseases (3) Both gender are included (4) The participants were at stage 3 of Parkinson’s disease, according the Hoehn and Yahr scale. (1) The examined patients did not have other coexisting neurodegenerative. (2)Mentally challenged (3) Orthopedic deformity. (1) Short form health survey. (20) Body posture questionnaire.This study included 30 patient 18 male and 12 female giving a sex ratio. Mean age of participant was 62 year. There were 15 patients in control group and 15 patients in experimental group. All patients completed treatment and evaluated at baseline and at the end of study. Mean value of sf-36 was 50.59 and 52.59 for experimental and control group respectively. These means later increase to 74.90 and 59.00 respectively with p value 0.001. Mean value of body posture questionnaire was 47.27 and50.07 for experimental and control group respectively. These mean later increase to72.47 and 59 respectively with p value 0.001 Statistically significant change was present for posture and quality of life with p&#60;0.001 for both group.Post intervention assessment will be done by body posture questionnaire and SF-36, for posture and quality of life assessment in 30 subjects meeting inclusion and exclusion criteria dividing in to two group by convenience.Group AGroup BThe obtained results revealed that the influence of applied program had a positive influence on posture and quality of life in people with Parkinson’s disease.When functional movement is applied on a regular basis, improvement of quality of life and everyday life activities can be noticed.

scholarly journals ASSOCIATION OF CLINICAL, PSYCHOEMOTIONAL STATUS AND THE PATHOGENETIC THERAPY WITH THE DEVELOPMENT OF REMISSION IN ADULT PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS

2018 ◽  
Vol 14 (1-2) ◽  
pp. 24-33
Author(s):  
M.B. Dzhus
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Femoral Neck ◽  
Juvenile Rheumatoid Arthritis ◽  
Adult Patients ◽  
Group I ◽  
Sf 36 ◽  
Pathogenetic Therapy ◽  
Active Disease

Relevance. The study of the frequency of remission in adult patients  with JRA treated in accordance with the "Unified clinical protocol for medical care for patients with juvenile rheumatoid arthritis" is relevant. Objective. The aim of our study was to evaluate the association of the clinical, psycho-emotional state and the pathogenetic therapy with the development of remission in adult patients with JRA. Materials and methods. 168 adult patients with JRA were examined at the transition period of the health care and adolescents. A retrospective analysis of medical records was performed to evaluate clinical symptoms and laboratory data in childhood and evaluated the clinical status, duration of the disease, activity on the JADAS and DAS-28 scales, quality of life, depression and alexithymia by scales SF-36, PHQ-9, TAS- 20, bone mineral density and methods of treatment in childhood and in adulthood. Results. All patients were divided into 2 groups: Group I - 138 patients (82.1%) with active disease at the time of examination, and II group - 30 patients (17.9%) who achieved remission. Patients who achieved remission did not differ by age at the time of the study, although the prevalence of women (58.1%) in the I group was determined, compared with 31.0% in the II group. Patients in both groups did not differ in height, however, patients with remission had a greater body weight (p <0.01) and BMI (p <0.01). There were no differences between the groups in the level of RF and A-CCP, ANA and the presence of HLA-B27, as well as in total cholesterol, LDL-cholesterol, glucose as risk factors for atherosclerosis (all p> 0.05). Patients with active disease had lower BMD in femoral neck and in ultradistal forearm area (all p <0.05). There were no difference in the the appointment of the IBT in doth groups. However, patients with remission more often did not receive GC in history (p <0.001) and at the time of examination (p <0.001), which is explained by less activity in the onset of the disease (p <0.05). Both groups did not differ in either the duration of the DMARD therapy, nor on the doses of methotrexate and sulfosalazine. Of the 53 patients with RF(+)/RF(-) polyarthritis - the most prognostically unfavorable variant of JRA, had arthritis > 3 joints (p <0.01), symmetrical arthritis (p <0.05), higher ESR ( p <0,05) compared patients with remission, and the absence of differences in the levels of CRP and JADAS. Conclusions. Patients with JRA in adulthood in 82.1% continue to have an active disease of varying degrees. The negative influence of the active disease on the BMD is found, mainly in the area of ​​femoral neck and ultradistal forearm in adult patients with active JRA compared with patients in remission. The significant influence of active disease in adulthood on the quality of life according to the SF-36 questionnaire was determined such as physical well-being, physical, role and social functioning, bodily pain, general health, and mental health compared with the group of patients in remission. An increase level of depression was found by PHQ-9 questionnaire in the I group compared to II group, although they did not differ in the level of Alexithymia. Patients who achieved remission compared with patients with active polyarthritis, were less likely to take GC in adulthood and reseived a higher dose of methotrexate.

scholarly journals Evaluation of the impact of high-tone therapy on cognitive disorders and quality of life in the complex treatment of patients with comorbid pathology

2021 ◽  
pp. 345-351
Author(s):  
Iryna SHMAKOVA ◽  
Svitlana PANINA ◽  
Volodymyr MYKHAYLENKO
Keyword(s):  
Quality Of Life ◽  
Cognitive Functions ◽  
Anxiety And Depression ◽  
High Tone ◽  
Complex Treatment ◽  
Group I ◽  
Sf 36 ◽  
Group Ii ◽  
The Impact

Introduction. Comorbidity is an independent risk factor for mortality and significantly influences the prognosis and quality of life. Purpose: to evaluate the impact of high-tone HiTOP 4 touch therapy on cognitive disorders and quality of life in the complex treatment of patients with comorbid pathology. Methods: complex treatment of 2 groups of patients with inclusion in the basic treatment regimen of high-tone therapy was carried out - a total of 80 patients (men - 34, women - 46) aged 41 to 79 years old, group I - patients with hypertension and chronic cerebral ischemia (CСI) - 38 patients and group II - patients with hypertension, CСI and concomitant diabetes mellitus (DM) type 2 - 42 patients. The average age in group I was 61.5, in group II - 65.5. Group I received lisinopril and amlodipine in one tablet, group II received metformin in addition to the above therapy. Both groups received a course of 10 sessions of high-tone therapy using the device HiTOP 4 touch (Germany) according to the general method: 2 electrodes on the feet, 2 on the forearms and one on the neck-collar area. All the patients were assessed for their cognitive condition, degree of anxiety and depression, and estimated for quality of life before and after a course of high-tone therapy. In order to do this, we used valid assessment tests, such as the Montreal Cognitive Assessment Scale (MoCA), the Hospital Anxiety and Depression Scale (HADS), and the SF-36 Quality of Life Questionnaire. Results: the course of high-tone therapy for patients with hypertension and CCI led to improved quality of life, on all indicators of the SF-36 scale, except for pain intensity, increased cognitive functions by 3.52 points on the MoCA scale, reduced anxiety by 2.06 points and depression by 1.92 points on the HADS scale. The course of high-tone therapy for patients with CCI, hypertension and type 2 DM resulted in a significant improvement of 5 out of 8 quality of life indicators on the SF-36 scale, cognitive functions by 2.27 points on the MoCA scale and reduced anxiety by 4.3 points, and depression by 0.53 points on the HADS scale. Conclusion: the inclusion of high-tone therapy in the complex treatment of patients with comorbid pathology improves cognitive functions, reduces anxiety and depression, improves quality of life. Keywords: comorbid pathology, high-tone therapy, cognitive functions, anxiety, depression, quality of life,

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