A new method for orthoscopic adjustment with the Fedorov stage

1959 ◽  
Vol 32 (246) ◽  
pp. 245-250
Author(s):  
A. F. Hallimond
Keyword(s):  
Standard Procedure ◽  
Symmetry Plane ◽  
Maximum Sensitivity ◽  
New Method ◽  
Wide Range

SummaryA new method is described to replace the standard procedure for completing the adjustment of an optical symmetry plane, with conditions for the accurate use of the biquartz. Extinction measurements are plotted to show the wide range of sensitivity (for the adjustment of A1 and A2) at various directions in the symmetry planes of a plagioclase. It is proposed that A1 and A2should be adjusted at different settings of A4 so as to obtain maximum sensitivity for each of those axes.

scholarly journals Using depolarization to quantify ice nucleating particle concentrations: a new method

2017 ◽  
Vol 10 (12) ◽  
pp. 4639-4657 ◽  
Author(s):  
Jake Zenker ◽  
Kristen N. Collier ◽  
Guanglang Xu ◽  
Ping Yang ◽  
Ezra J. T. Levin ◽  
...  
Keyword(s):  
Standard Procedure ◽  
Diffusion Chamber ◽  
Operating Conditions ◽  
Ice Crystals ◽  
New Method ◽  
State University ◽  
Analysis Method ◽  
Colorado State University ◽  
Nominal Size ◽  
Wide Range

Abstract. We have developed a new method to determine ice nucleating particle (INP) concentrations observed by the Texas A&M University continuous flow diffusion chamber (CFDC) under a wide range of operating conditions. In this study, we evaluate differences in particle optical properties detected by the Cloud and Aerosol Spectrometer with POLarization (CASPOL) to differentiate between ice crystals, droplets, and aerosols. The depolarization signal from the CASPOL instrument is used to determine the occurrence of water droplet breakthrough (WDBT) conditions in the CFDC. The standard procedure for determining INP concentration is to count all particles that have grown beyond a nominal size cutoff as ice crystals. During WDBT this procedure overestimates INP concentration, because large droplets are miscounted as ice crystals. Here we design a new analysis method based on depolarization ratio that can extend the range of operating conditions of the CFDC. The method agrees reasonably well with the traditional method under non-WDBT conditions with a mean percent error of ±32.1 %. Additionally, a comparison with the Colorado State University CFDC shows that the new analysis method can be used reliably during WDBT conditions.

scholarly journals Design of Personalized Devices—The Tradeoff between Individual Value and Personalization Workload

2020 ◽  
Vol 11 (1) ◽  
pp. 241
Author(s):  
Juliane Kuhl ◽  
Andreas Ding ◽  
Ngoc Tuan Ngo ◽  
Andres Braschkat ◽  
Jens Fiehler ◽  
...  
Keyword(s):  
Customer Value ◽  
Early Stage ◽  
Treatment Success ◽  
Product Family ◽  
Flow Diverter ◽  
New Method ◽  
Product Families ◽  
Wide Range ◽  
The Individual ◽  
Individual Value

Personalized medical devices adapted to the anatomy of the individual promise greater treatment success for patients, thus increasing the individual value of the product. In order to cater to individual adaptations, however, medical device companies need to be able to handle a wide range of internal processes and components. These are here referred to collectively as the personalization workload. Consequently, support is required in order to evaluate how best to target product personalization. Since the approaches presented in the literature are not able to sufficiently meet this demand, this paper introduces a new method that can be used to define an appropriate variety level for a product family taking into account standardized, variant, and personalized attributes. The new method enables the identification and evaluation of personalizable attributes within an existing product family. The method is based on established steps and tools from the field of variant-oriented product design, and is applied using a flow diverter—an implant for the treatment of aneurysm diseases—as an example product. The personalization relevance and adaptation workload for the product characteristics that constitute the differentiating product properties were analyzed and compared in order to determine a tradeoff between customer value and personalization workload. This will consequently help companies to employ targeted, deliberate personalization when designing their product families by enabling them to factor variety-induced complexity and customer value into their thinking at an early stage, thus allowing them to critically evaluate a personalization project.

scholarly journals Gradient HPLC in the determination of drug lipophilicity and acidity

2001 ◽  
Vol 73 (9) ◽  
pp. 1465-1475 ◽  
Author(s):  
Roman Kaliszan ◽  
Piotr Haber ◽  
Tomasz Baczek ◽  
Danuta Siluk
Keyword(s):  
Mobile Phase ◽  
High Performance ◽  
Standard Procedure ◽  
Gradient Elution ◽  
Log P ◽  
Retention Data ◽  
Organic Modifier ◽  
Wide Range ◽  
Aqueous Component ◽  
Initial Ph

The linear-solvent strength (LSS) model of gradient elution in high-performance liquid chromatography (HPLC) has been demonstrated to provide parameters of lipophilicity and acidity of analytes. pKa and log kw values are determined in three gradient runs. The first two experiments use an aqueous buffered eluent with a wide-range organic modifier gradient at pH of buffer, providing suppression of ionization of the analyte. That experiment allows an estimate of contents of the organic modifier in the mobile phase (%B), producing requested retention coefficient, k, for the nonionized form of the analyte. The next experiment is carried out with the latter %B and a pH-gradient of the aqueous component of the eluent that is sufficient to overlap possible pKa value of the analyte. The initial pH of the buffer used to make the mobile phase is selected to insure that the analyte is in nonionized form. The resulting retention time allows an estimate of pKa in a solvent of the given %B.The log kw parameter obtained correlated well with the corresponding value obtained by the standard procedure of extrapolation of retention data determined in a series of isocratic measurements. The correlation between log kw and the reference parameter of lipophilicity, log P, was very good for a series of test analytes. The values of pKa were found to correlate with the literature pKa data determined in water for a set of aniline derivatives studied.

Cholinium-amino acid based ionic liquids: a new method of synthesis and physico-chemical characterization

2015 ◽  
Vol 17 (32) ◽  
pp. 20687-20698 ◽  
Author(s):  
Serena De Santis ◽  
Giancarlo Masci ◽  
Francesco Casciotta ◽  
Ruggero Caminiti ◽  
Eleonora Scarpellini ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Amino Acid ◽  
Room Temperature ◽  
Chemical Characterization ◽  
New Method ◽  
Room Temperature Ionic Liquids ◽  
Synthetic Method ◽  
Chemical Structures ◽  
Physico Chemical ◽  
Wide Range

Fourteen cholinium-amino acid based room temperature ionic liquids were prepared using a cleaner synthetic method. Chemicophysical properties were well correlated with the wide range of amino acid chemical structures.

“ROLE OF FNAC IN THE DIAGNOSIS OF SALIVARY GLAND LESION”

2021 ◽  
pp. 69-71
Author(s):  
Rifat Qureishi ◽  
M.H. Usmani ◽  
U.R. Singh ◽  
P.C. Kol
Keyword(s):  
Salivary Gland ◽  
Diagnostic Accuracy ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Standard Procedure ◽  
Neck Region ◽  
Invasive Procedure ◽  
Sensitivity Index ◽  
Cytologic Diagnosis ◽  
Wide Range

Background: Fine needle aspiration cytology (FNAC) has been used for diagnosis of salivary gland lesions for many years. Various studies in the existing literature have shown a wide range of sensitivity and diagnostic accuracy of cytologic diagnosis. FNAC is a safe, simple, cost effective, 1-4 accurate and minimal invasive procedure for the evaluation of salivary gland lesions. FNAC is not only useful in planning denitive preoperative 2,5-6 diagnosis but also can prevent unnecessary surgical intervention. Salivary gland swelling occur more commonly in 3rd decade of life with equal sex incidence. Parotid is one of the most commonly involved glands in the head & neck region swellings. FNAC appears to be highly sensitive for benign tumours and highly specic for malignant tumors and it should be the rst line of investigation in evaluating the salivary gland pathologies. 7 Early diagnosis and appropriate management carries good prognosis. Methods: Patients with suspected salivary gland enlargements, referred for FNAC, were included in this study. FNAC was performed by using the standard procedure. Cytologic diagnosis was compared with histopathologic diagnosis wherever it was available. Results: In the present study conducted in the department of pathology, Shyam Shah Medical College Rewa MP, over a period of 5 years, 152 Patients with suspected salivary gland enlargements were retrospectively appraised. The benign lesions of salivary gland were 133 (87.5%), out of which Pleomorphic adenoma was diagnosed in 75 (56.39%) cases, clinical correlation was found in 58 (77.33%) cases. 29 cases were subsequently correlated with histopathological examination 26 correctly correlated and the diagnostic accuracy of FNAC was found to be 89.65%. Inammatory lesions were proved correct in 08 out of 10 cases after histopathology. Therefore, accuracy of FNAC was 80.0%. Malignant lesions of salivary gland were found in 19 cases, out of which 15 (78.94%) cases correlated with clinical diagnosis. 13 cases were subjected to histopathology 10 correctly correlated and the diagnostic accuracy of FNAC was found to be 76.92%. Overall diagnostic accuracy of FNAC was 84.61%. Conclusion:In conclusions it can be established that FNAC is an efcient and accurate procedure with high sensitivity index, and its usefulness is enhanced due to it being a relatively easy procedure which can be carried out even on outdoor patients.

Measurement of carbonization region on leather cutting in CO2 and diode laser-based laser beam process

2021 ◽  
pp. 095440892110563
Author(s):  
S. Vasanth ◽  
T. Muthuramalingam
Keyword(s):  
Image Processing ◽  
Laser Beam ◽  
Diode Laser ◽  
Heat Affected Zone ◽  
Diode Lasers ◽  
Standard Procedure ◽  
Wide Range ◽  
Thermal Influence ◽  
Cutting Experiments ◽  
Measurement Approach

There is a quite wide range of animal leathers such as cow leather, sheep leather and buffalo leather used for leather garments and leather goods such as bags, wallets and other customized leather articles. The drawbacks of manual cutting can be eliminated by laser-based cutting. However, unwanted carbonization is happened owing to the higher thermal influence. There is no standard procedure or method available to measure the carbonization region on leather cutting. Diode lasers can process leather rapidly and efficiently. In the present work, an attempt was proposed to introduce the image processing-based measurement approach in leather cutting using CO2 laser and diode laser. The cutting experiments were performed on sheep leather with a thickness of 1 mm. It was found that the proposed can effectively measure the heat-affected zone (HAZ) of leather cutting. It has also been found that diode laser could produce lower HAZ than CO2 laser on leather cutting.

scholarly journals Plane thermonuclear detonation waves initiated by proton beams and quasi-one-dimensional model of fast ignition

2014 ◽  
Vol 33 (1) ◽  
pp. 65-80 ◽  
Author(s):  
Alexander A. Charakhch'yan ◽  
Konstantin V. Khishchenko
Keyword(s):  
Detonation Wave ◽  
Fusion Reaction ◽  
Plasma Heating ◽  
Symmetry Plane ◽  
Detonation Waves ◽  
Proton Beams ◽  
One Dimensional ◽  
Wide Range ◽  
The One ◽  
Α Particles

AbstractThe one-dimensional problem on bilatiral irradiation by proton beams of the plane layer of condensed DT mixture with length 2H and density ρ0 ≤ 100ρs, where ρs is the fuel solid-state density at atmospheric pressure and temperature of 4 K, is considered. The proton kinetic energy is 1 MeV, the beam intensity is 1019 W/cm2 and duration is 50 ps. A mathematical model is based on the one-fluid two-temperature hydrodynamics with a wide-range equation of state of the fuel, electron and ion heat conduction, DT fusion reaction kinetics, self-radiation of plasma and plasma heating by α-particles. If the ignition occurs, a plane detonation wave, which is adjacent to the front of the rarefaction wave, appears. Upon reflection of this detonation wave from the symmetry plane, the flow with the linear velocity profile along the spatial variable x and with a weak dependence of the thermodynamic functions of x occurs. An appropriate solution of the equations of hydrodynamics is found analytically up to an arbitrary constant, which can be chosen so that the analytical solution describes with good accuracy the numerical one. The gain with respect to the energy of neutrons G ≈ 200 at Hρ0 ≈ 1 g/cm2, and G > 2000 at Hρ0 ≈ 5 g/cm2. To evaluate the ignition energy Eig of cylindrical targets, the quasi-1D model, limiting trajectories of α-particles by a cylinder of a given radius, is suggested. The model reproduces the known theoretical dependence Eig ~ ρ0−2 and gives Eig = 160 kJ for ρ0 = 100ρs ≈ 22 g/cm3.

scholarly journals A new entropy-variable-based discretization method for minimum entropy moment approximations of linear kinetic equations

2021 ◽  
Author(s):  
Tobias Leibner ◽  
Mario Ohlberger
Keyword(s):  
Optimization Problems ◽  
Hessian Matrix ◽  
Computational Cost ◽  
Kinetic Equations ◽  
New Method ◽  
Minimum Entropy ◽  
Reduced Basis ◽  
Simple Task ◽  
Wide Range ◽  
The Moment

In this contribution we derive and analyze a new numerical method for kinetic equations based on a variable transformation of the moment approximation. Classical minimum-entropy moment closures are a class of reduced models for kinetic equations that conserve many of the fundamental physical properties of solutions. However, their practical use is limited by their high computational cost, as an optimization problem has to be solved for every cell in the space-time grid. In addition, implementation of numerical solvers for these models is hampered by the fact that the optimization problems are only well-defined if the moment vectors stay within the realizable set. For the same reason, further reducing these models by, e.g., reduced-basis methods is not a simple task. Our new method overcomes these disadvantages of classical approaches. The transformation is performed on the semi-discretized level which makes them applicable to a wide range of kinetic schemes and replaces the nonlinear optimization problems by inversion of the positive-definite Hessian matrix. As a result, the new scheme gets rid of the realizability-related problems. Moreover, a discrete entropy law can be enforced by modifying the time stepping scheme. Our numerical experiments demonstrate that our new method is often several times faster than the standard optimization-based scheme.

Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer.

1986 ◽  
Vol 32 (8) ◽  
pp. 1551-1554 ◽  
Author(s):  
N Watanabe ◽  
S Kamei ◽  
A Ohkubo ◽  
M Yamanaka ◽  
S Ohsawa ◽  
...  
Keyword(s):  
Trichloroacetic Acid ◽  
Protein Concentration ◽  
Urinary Protein ◽  
New Method ◽  
Normal Range ◽  
Pyrogallol Red ◽  
Wide Range ◽  
Biuret Method

Abstract In this new method for determining urinary protein, the reaction is complete within 10 min at 37 degrees C. This method is applicable to automated as well as manual measurements. Protein concentration and absorbance at 600 nm are linearly related throughout a wide range of concentrations, 10 to 16 000 mg/L. However, the chromogenicity of the gamma-globulins in this method is 70% of that of albumin, as estimated from results by a biuret method. Within-run CVs were less than 3.3%; the day-to-day CV was 2.9%. Errors due to interfering components in urine are less than 2%. The normal range for urinary protein as measured by this method was from 28 to 141 mg/day. Results by this method (y) and by a trichloroacetic acid-biuret method (x) correlated well (n = 80, r = 0.995; y = 0.99x - 2.9).

scholarly journals Development of a shutterless continuous rotation method using an X-ray CMOS detector for protein crystallography

2009 ◽  
Vol 42 (6) ◽  
pp. 1165-1175 ◽  
Author(s):  
Kazuya Hasegawa ◽  
Kunio Hirata ◽  
Tetsuya Shimizu ◽  
Nobutaka Shimizu ◽  
Takaaki Hikima ◽  
...  
Keyword(s):  
Data Collection ◽  
Dynamic Range ◽  
Protein Structures ◽  
Protein Crystallography ◽  
New Method ◽  
Oxide Semiconductor ◽  
X Ray ◽  
Rotation Method ◽  
Continuous Rotation ◽  
Wide Range

A new shutterless continuous rotation method using an X-ray complementary metal-oxide semiconductor (CMOS) detector has been developed for high-speed, precise data collection in protein crystallography. The principle of operation and the basic performance of the X-ray CMOS detector (Hamamatsu Photonics KK C10158DK) have been shown to be appropriate to the shutterless continuous rotation method. The data quality of the continuous rotation method is comparable to that of the conventional oscillation method using a CCD detector and, furthermore, the combination with fine φ slicing improves the data accuracy without increasing the data-collection time. The new method is more sensitive to diffraction intensity because of the narrow dynamic range of the CMOS detector. However, the strong diffraction spots were found to be precisely measured by recording them on successive multiple images by selecting an adequate rotation step. The new method has been used to successfully determine three protein structures by multi- and single-wavelength anomalous diffraction phasing and has thereby been proved applicable in protein crystallography. The apparatus and method may become a powerful tool at synchrotron protein crystallography beamlines with important potential across a wide range of X-ray wavelengths.

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