Relationship between hormones that decrease blood glucose and the resident bacterial content of the intestine

2020 ◽  
Author(s):  
Joan Josep Vendrell
Keyword(s):  
Blood Glucose ◽  
Decrease Blood Glucose ◽  
Bacterial Content

scholarly journals Efek Hipoglikemik Kecambah Beras Merah pada Tikus yang Diinduksi STZ-NA dengan Parameter Kadar Insulin, Indeks HOMA-IR dan HOMA β (Hypoglycemic Effect of Red Rice Germ on Insulin Levels, HOMA-IR, and HOMA β Index of STZ-NA Induced Rats)

2017 ◽  
Vol 36 (4) ◽  
pp. 433
Author(s):  
Nurhidajah Nurhidajah ◽  
Nurrahman Nurrahman
Keyword(s):  
Insulin Resistance ◽  
Blood Glucose ◽  
Insulin Level ◽  
Control Group ◽  
Standard Diet ◽  
Red Rice ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Post Test ◽  
Decrease Blood Glucose

The process of germination of grains such as rice, could increase some nutritional values of  amino acids and dietary fiber. Red rice and its sprouts are believed to be able to decrease blood glucose in patients with diabetes mellitus (DM). The aim of this study was to evaluate the hypoglycemic effect of red rice sprouts in STZ-NA induced diabetic rats on blood glucose level, insulin level, and HOMA-IR and HOMA-β index. This experimental study was conducted based on randomized post test only control group design using 24 male Wistar rats aged 2.5 months. Rats were divided into 4 groups, one group without induction of STZ-NA fed with a standard diet (control) and three groups of STZ- NA induced with a standard diet, red rice and red rice germ. Experiments were conducted for 6 weeks. The results showed that sprouted red rice lowered blood glucose levels by 61.88 % and the value of HOMA-IR (insulin resistance parameters) by 56.82%. Insulin level increased by 16.35 % and HOMA-β by 763.6 %. This study showed that red rice germ was able to decrease blood glucose levels and increase insulin resistance of DM rats and the strength of the pancreatic beta cells. ABSTRAKProses perkecambahan biji-bijian seperti beras, dapat meningkatkan beberapa nilai gizi seperti asam amino dan serat pangan. Beras merah dan kecambahnya diyakini mampu menurunkan glukosa darah pada penderita diabetes melitus (DM). Tujuan penelitian ini adalah mengevaluasi efek hipoglikemik kecambah beras merah pada tikus diabetes yang diinduksi STZ-NA terhadap kadar glukosa darah, insulin, serta indeks HOMA-IR dan HOMA β. Penelitian ini bersifat eksperimental in vivo pada hewan coba tikus Wistar jantan usia 2,5 bulan sebanyak 24 ekor dengan desain penelitian randomized post test only control group. Tikus dibagi menjadi 4 kelompok, masing-masing 1 kelompok tanpa induksi STZ-NA dengan diet standar dan 3 kelompok diinduksi STZ-NA dengan diet standar, beras merah dan kecambah beras merah. Percobaan dilakukan selama 6 minggu. Hasil penelitian menunjukkan kecambah beras merah mampu menurunkan kadar glukosa darah sebesar 61,88 % dan nilai HOMA-IR (parameter resistensi insulin) 56,82 %. Kadar insulin meningkat 16,35 % dan HOMA β 763,6 %. Disimpulkan, kecambah beras merah mampu menurunkan kadar glukosa darah dan memperbaiki kondisi resistensi insulin tikus DM, dan kekuatan sel beta pankreas.

scholarly journals Acute hunger does not always undermine prosociality

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Jan A. Häusser ◽  
Christina Stahlecker ◽  
Andreas Mojzisch ◽  
Johannes Leder ◽  
Paul A. M. Van Lange ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Public Goods ◽  
Meta Analysis ◽  
Dictator Game ◽  
Lay Theories ◽  
Total N ◽  
Public Goods Games ◽  
Decrease Blood Glucose ◽  
Quasi Experimental ◽  
Stark Contrast

Abstract It has been argued that, when they are acutely hungry, people act in self-protective ways by keeping resources to themselves rather than sharing them. In four studies, using experimental, quasi-experimental, and correlational designs (total N = 795), we examine the effects of acute hunger on prosociality in a wide variety of non-interdependent tasks (e.g. dictator game) and interdependent tasks (e.g. public goods games). While our procedures successfully increase subjective hunger and decrease blood glucose, we do not find significant effects of hunger on prosociality. This is true for both decisions incentivized with money and with food. Meta-analysis across all tasks reveals a very small effect of hunger on prosociality in non-interdependent tasks (d = 0.108), and a non-significant effect in interdependent tasks (d = −0.076). In study five (N = 197), we show that, in stark contrast to our empirical findings, people hold strong lay theories that hunger undermines prosociality.

Fetal glucose utilization in response to maternal starvation and acute hyperketonemia

1989 ◽  
Vol 256 (6) ◽  
pp. E699-E703 ◽  
Author(s):  
A. Leturque ◽  
S. Hauguel ◽  
J. P. Revelli ◽  
A. F. Burnol ◽  
J. Kande ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Ketone Body ◽  
Glucose Utilization ◽  
Fetal Liver ◽  
Rat Tissues ◽  
Pregnant Rats ◽  
Hindlimb Muscles ◽  
Decrease Blood Glucose ◽  
Beta Hydroxybutyrate

The effects of maternal hypoglycemia and/or hyperketonemia on glucose utilization by individual fetal rat tissues have been studied in vivo. To decrease blood glucose and to raise fetal blood ketone body concentrations, 19-day pregnant rats were submitted to 48 or 96 h of starvation. To differentiate between the effects of decreased blood glucose and increased ketone body concentrations, fed pregnant rats were infused for 2 h with DL-beta-hydroxybutyrate. After 96 h of maternal starvation, fetal 2-deoxy-D-glucose (2DG) uptake decreased from 13.6 +/- 0.5 to 8.6 +/- 1.15 micrograms.min-1.g-1. This was mainly due to a decrease in 2DG uptake by fetal hindlimb muscles and heart. By contrast, 2DG uptake in fetal liver and brain was not affected by maternal starvation. Acute hyperketonemia in fed pregnant rats induced a 23% decrease in 2DG uptake by the whole fetus mainly as the result of a lowered 2DG uptake in fetal hindlimb muscles. These data suggest that fetal 2DG uptake does not simply depend on lowered blood glucose level during maternal starvation but that other hormonal, cardiovascular, or metabolic adaptations are implicated. In the rat, most of the fetal tissues including brain are protected against maternal hypoglycemia.

scholarly journals Pengaruh suplementasi β-carotene terhadap kadar glukosa darah dan kadar malondialdehida pada tikus sprague dawley yang diinduksi Streptozotocin

2014 ◽  
Vol 2 (2) ◽  
pp. 41-46
Author(s):  
Elida Soviana ◽  
Banundari Rachmawati ◽  
Nyoman Suci Widyastiti
Keyword(s):  
Free Radicals ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Negative Control ◽  
Male Rats ◽  
Sprague Dawley ◽  
Significant Difference ◽  
Decrease Blood Glucose ◽  
Β Carotene

Background : Hyperglycemia on diabetes mellitus can cause increasing of free radicals production. Free radicals caused lipid peroxidation reaction by forming malondialdehyde (MDA). β-carotene has antioxidant activity may inhibit the formation of ROS.Objective : To prove the effect of multilevel doses β-carotene 1 mg/kg BW, 20 mg/kg BW and 20 mg/kg BW on alternate days within 30 days orally supplementation on blood glucose level and MDA level on Sprague Dawley male rats induced by streptozotocin (STZ). Methods : Thirty rats were randomly divided into 5 groups: X1=Negative control/diabetic, X2 (STZ 40 mg/kg BW + BC 1 mg/kg BW), X3 (STZ 40 mg/kg BW + BC 10mg/kg BW), X4 (STZ 40 mg/kg BW + BC 20 mg/kg BW), X5 (technic control/non diabetic). β-Carotene supplementation was given by nasogastric tube on alternate days within thirty days. Blood glucose level was measured by GOD-PAP and MDA level by ELISA with TBARS methods. Data was analized using paired t-test, wilcoxon, one way anova and post hoc bonferroni. Results : there was a significant difference of blood glucose level (p = 0,0001) and MDA level (p = 0,0001) after suplementation β-carotene on alternate days within 30 days orally. β-carotene 10 mg/kg BW was the most effective and efficient dose to lowering blood glucose, while 20 mg/kg BW to lowering MDA level. Conclusion : The multilevel doses β-carotene (1 mg/kg BW, 10 mg/kg BW and 20 mg/kg BW) on alternate days within 30 days orally supplementation can decrease blood glucose and MDA level. β-carotene 10 mg/kg BW is the most effecetive and efficient to decrease blood glucose and β-carotene 20 mg/kg BW to decrease MDA level.

scholarly journals Do Sri Lankan meals help decrease blood glucose response?

2009 ◽  
Vol 54 (2) ◽  
pp. 39 ◽  
Author(s):  
U P K Hettiaratchi ◽  
S Ekanayake ◽  
J Welihinda
Keyword(s):  
Blood Glucose ◽  
Sri Lankan ◽  
Glucose Response ◽  
Blood Glucose Response ◽  
Decrease Blood Glucose

scholarly journals THE EFFECT OF ETHANOLIC EXTRACT OF DAYAK ONION (Eleutherine palmifolia (L) MERR) TUBER ON BLOOD GLUCOSE AND INSULIN LEVEL OF STREPTOZOTOCIN-INDUCED DIABETIC WISTAR RAT

2019 ◽  
Vol 7 (4) ◽  
pp. 38-42
Author(s):  
Hasni Yaturramadhan ◽  
Aminah Dalimunthe ◽  
Tri Widyawati
Keyword(s):  
Blood Glucose ◽  
Ethanolic Extract ◽  
Insulin Level ◽  
Wistar Rat ◽  
Antidiabetic Activity ◽  
Plasma Insulin Concentration ◽  
Insulin Levels ◽  
Glucose Levels ◽  
Reduce Blood Glucose ◽  
Decrease Blood Glucose

Objectives: The current investigation was conducted to examine the ability of ethanolic extract from onion dayak (Eleutherine palmifolia) (L) (Merr) tuber to reduce blood glucose and increase insulin production in streptozotocin-induced diabetic wistar rat. Materials and Methods: Extraction was accomplished using maceration method with 96% ethanol. Antidiabetic activity was evaluated using observation of blood glucose levels utilize glucometer (Easy Touch). Analysis of insulin plasma concentration was determined utilize the Insulin Elisa Kit (Chem Cruz). Results: The administration of dayak onion extract as a form of therapy in diabetes, although it has not been able to increase insulin levels significantly, but has shown a tendency to increase insulin levels at higher doses of 500 mg/bw. Conclusion: Ethanolic extract from dayak onion tuber exhibited activity of decrease blood glucose level and increase plasma insulin concentration in streptozotocin-induced diabetic wistar rat.  

scholarly journals Antihyperglycemic Activity of Aqueous Extract of Insulin Leaves (Tithonia diversifolia) on Hyperglycemic Rats (Rattus norvegicus)

2018 ◽  
Vol 10 (3) ◽  
pp. 636-641
Author(s):  
Anisa Rachma Sari ◽  
Tyas Rini Saraswati ◽  
Enny Yusuf Wachidah Yuniwarti
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Aqueous Extract ◽  
Rattus Norvegicus ◽  
Tithonia Diversifolia ◽  
Antihyperglycemic Activity ◽  
Treatment Groups ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Decrease Blood Glucose

Insulin leave (Tithonia diversifolia (Hemsl.) A. Gray) empirically used by people as antihyperglycemic drugs. The study was aimed to evaluate antihyperglycemic activity as well as to determine the most optimum dose of T. diversifolia to reduce blood glucose levels. Hyperglycemic condition was induced to male Rattus norvegicus rats by intraperitoneal injection of alloxan at a dose of 150 mg/kg bw (body weight). In this study, completely randomized design was performed with three treatment groups and five times repetition. Group P1 received glibenclamide 10 mg/kg bw, P2 received aqueous extract of T. diversifolia at a dose of 150 mg/kg bw, P3 received aqueous extract of T. diversifolia at a dose of 300 mg/kg bw. Administration of both glibenclamide and aqueous extract of T. diversifolia was conducted orally for 28 days. Data were analyzed using Anova and Duncan’s test with 95% confidence level (α = 0.05). The results showed that the mean percentage of decrease in blood glucose levels, drink intake and body weight of all treatment groups were not significantly different (p>0.05). Data of feed intake showed that P1 was significantly different from P2 (p<0.05), but P2 was not significantly different from P3 (p>0.05). Based on the result of this research, it was found that the low doses of aqueous extract of T. diversifolia has the same ability to decrease blood glucose level compared to glibenclamide. Futhermore, this study provide some information that can be used as preclinical analysis to determine effective doses of aqueous extract of T. diversifolia to decrease blood glucose levels.  

Sign in / Sign up

Export Citation Format

Share Document