Longitudinal Zeolite-Iron Oxide Nanocomposite Deposited Capacitance Biosensor for Interleukin-3 in Sepsis Detection

AbstractSepsis is an extreme condition involving a physical response to severe microbial infection and causes fatal and life-threatening issues. Sepsis generates during the chemicals release with the immune system into the bloodstream for fighting against an infection, which causes the inflammation and leads to the medical emergency. A complexed longitudinal zeolite and iron oxide nanocomposite was extracted from coal mine fly ash and utilized to improve the surface characteristics of the capacitance biosensor to identify sepsis attacks. Anti-interleukin-3 (anti-IL-3) antibody was attached to the zeolite- and iron oxide-complexed capacitance electrode surface through an amine linker to interact with the sepsis biomarker IL-3. The morphological and chemical components of the nanocomplex were investigated by FESEM, FETEM, and EDX analyses. At approximately 30 nm, the longitudinal zeolite and iron oxide nanocomposite aided in attaining the limit of IL-3 detection of 3 pg/mL on the linear curve, with a regression coefficient (R2) of 0.9673 [y = 1.638x − 1.1847]. A lower detection limit was achieved in the dose-dependent range (3–100 pg/mL) due to the higher amount of antibody immobilization on the sensing surface due to the nanomaterials and the improved surface current. Furthermore, control experiments with relevant biomolecules did not show capacitance changes, and spiked IL-3 in human serum increased capacitance, indicating the specific and selective detection of IL-3. This study identifies and quantifies IL-3 via potentially useful methods and helps in diagnosing sepsis attack.

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Machinability Investigations of Inconel-800 Super Alloy under Sustainable Cooling Conditions

Materials ◽

10.3390/ma11112088 ◽

2018 ◽

Vol 11 (11) ◽

pp. 2088 ◽

Cited By ~ 44

Author(s):

Munish Gupta ◽

Catalin Pruncu ◽

Mozammel Mia ◽

Gurraj Singh ◽

Sunpreet Singh ◽

...

Keyword(s):

Chip Morphology ◽

Surface Characteristics ◽

Machining Process ◽

Cutting Fluid ◽

Critical Parameters ◽

Chemical Components ◽

Cutting Fluids ◽

Dry Machining ◽

Manufacturing Method ◽

Inconel 800

With regard to the manufacturing of innovative hard-machining super alloys (i.e., Inconel-800), a potential alternative for improving the process is using a novel cutting fluid approach. Generally, the cutting fluids allow the maintenance of a better tool topography that can generate a superior surface quality of machined material. However, the chemical components of fluids involved in that process may produce harmful effects on human health and can trigger environmental concerns. By decreasing the cutting fluids amount while using sustainable methods (i.e., dry), Near Dry Machining (NDM) will be possible in order to resolve these problems. This paper discusses the features of two innovative techniques for machining an Inconel-800 superalloy by plain turning while considering some critical parameters such as the cutting force, surface characteristics (Ra), the tool wear rate, and chip morphology. The research findings highlight the near-dry machining process robustness over the dry machining routine while its great potential to resolve the heat transfer concerns in this manufacturing method was demonstrated. The results confirm other benefits of these methods (i.e., NDM) linked to the sustainability aspects in terms of the clean process, friendly environment, and permits as well as in terms of improving the manufacturing characteristics.

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Surface characteristics and wear performance of laser surface engineered iron oxide coatings on cast aluminium alloy

Materials Science and Technology ◽

10.1179/026708302225004892 ◽

2002 ◽

Vol 18 (9) ◽

pp. 1036-1040 ◽

Cited By ~ 4

Author(s):

A. Dasari ◽

S. Nayak ◽

R. D. K. Misra ◽

O. O. Popoola ◽

N. B. Dahotre

Keyword(s):

Iron Oxide ◽

Aluminium Alloy ◽

Surface Characteristics ◽

Laser Surface ◽

Oxide Coatings ◽

Wear Performance ◽

Cast Aluminium ◽

Iron Oxide Coatings

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Iron Oxide Rust as Raw Material for the Production of Red Pigment in Paint Industry

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.660.229 ◽

2014 ◽

Vol 660 ◽

pp. 229-233 ◽

Cited By ~ 2

Author(s):

Chee Kiong Sia ◽

S. Hakimi Mohd ◽

Ong Pauline ◽

Kuang Jie Fie

Keyword(s):

Iron Oxide ◽

Hardness Test ◽

Raw Material ◽

Chemical Components ◽

Sintering Process ◽

Optimum Ratio ◽

Ph Indicator ◽

Pencil Hardness ◽

Analysis Study ◽

Paint Industry

In this study, the potential of rust as a pigment in paint technology via sintering process was investigated. Iron (III) nitrate was the raw material used to make rust or iron oxide. The characteristics of iron oxide were analyzed. Moreover, iron oxide was mixed with other chemical components to make paint. The properties of paint in both liquid state and solid state were determined by portable field viscometer, pH indicator, glossmeter, pencil hardness test, and tape adhesive test. The optimum ratio of paint components for this study where used iron oxide as pigment. The other properties of pigments and paints will be conducted in the analysis study.

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Caveolin-1 and CDC42 mediated endocytosis of silica-coated iron oxide nanoparticles in HeLa cells

Beilstein Journal of Nanotechnology ◽

10.3762/bjnano.6.16 ◽

2015 ◽

Vol 6 ◽

pp. 167-176 ◽

Cited By ~ 26

Author(s):

Nils Bohmer ◽

Andreas Jordan

Keyword(s):

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Hela Cells ◽

Superparamagnetic Iron Oxide ◽

Surface Characteristics ◽

Oxide Nanoparticles ◽

Caveolin 1 ◽

Model Cell ◽

Dynamin 2

Nanomedicine is a rapidly growing field in nanotechnology, which has great potential in the development of new therapies for numerous diseases. For example iron oxide nanoparticles are in clinical use already in the thermotherapy of brain cancer. Although it has been shown, that tumor cells take up these particles in vitro, little is known about the internalization routes. Understanding of the underlying uptake mechanisms would be very useful for faster and precise development of nanoparticles for clinical applications. This study aims at the identification of key proteins, which are crucial for the active uptake of iron oxide nanoparticles by HeLa cells (human cervical cancer) as a model cell line. Cells were transfected with specific siRNAs against Caveolin-1, Dynamin 2, Flotillin-1, Clathrin, PIP5Kα and CDC42. Knockdown of Caveolin-1 reduces endocytosis of superparamagnetic iron oxide nanoparticles (SPIONs) and silica-coated iron oxide nanoparticles (SCIONs) between 23 and 41%, depending on the surface characteristics of the nanoparticles and the experimental design. Knockdown of CDC42 showed a 46% decrease of the internalization of PEGylated SPIONs within 24 h incubation time. Knockdown of Dynamin 2, Flotillin-1, Clathrin and PIP5Kα caused no or only minor effects. Hence endocytosis in HeLa cells of iron oxide nanoparticles, used in this study, is mainly mediated by Caveolin-1 and CDC42. It is shown here for the first time, which proteins of the endocytotic pathway mediate the endocytosis of silica-coated iron oxide nanoparticles in HeLa cells in vitro. In future studies more experiments should be carried out with different cell lines and other well-defined nanoparticle species to elucidate possible general principles.

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Study on arsenic removal process from water

Mongolian Journal of Chemistry ◽

10.5564/mjc.v12i0.172 ◽

2014 ◽

Vol 12 ◽

pp. 53-55

Author(s):

B Bayarmaa ◽

E Selenge ◽

Yang Min

Keyword(s):

Magnetic Properties ◽

Iron Oxide ◽

Adsorption Capacity ◽

Ferric Oxide ◽

Arsenic Removal ◽

Ph Dependence ◽

Surface Characteristics ◽

Arsenic Adsorption ◽

Ferric Oxides ◽

The Relationship

In this study a novel adsorbent, iron oxide, is used for As (V) or As (III) removal. Some ferric oxides have been reported to be effective for arsenic removal. Ferric oxides powder is a good adsorbent material since it’s has magnetic properties and a good adsorption capacity. The main purpose of this study has been focused on to study the relationship between adsorption capacity (ability, performance) and the surface characteristics of the ferric oxide. Prepared sample’s capacity was evaluated. The value was 26.1-67.4 mg/g for As (V) and 20.5-47.8 mg/g for As (III). pH dependence was evaluated and when pH increasing, adsorption capacity was decreased. The kinetic was evaluated and about 12 hours reached equilibrium and a capacity of 49 mg/g for As (V) and 42 mg/g for As(III) was gained. The kinetic constants for arsenic adsorption on the ferrihydrite adsorbent’s were fitted.DOI: http://dx.doi.org/10.5564/mjc.v12i0.172 Mongolian Journal of Chemistry Vol.12 2011: 53-55

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Microscopic versus process parameters in heavy-oil upgrading

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010012223x ◽

1992 ◽

Vol 50 (1) ◽

pp. 366-367

Author(s):

V.A. Munoz ◽

R.J. Mikula ◽

C. Payette ◽

W.W. Lam

Keyword(s):

Molecular Weight ◽

Liquid Fuels ◽

Chemical Components ◽

Heavy Oils ◽

Synthetic Fuels ◽

High Hydrogen ◽

Optical Texture ◽

Polar Groups ◽

Anisotropic Character ◽

Planar Molecules

The transformation of high molecular weight components present in heavy oils into useable liquid fuels requires their decomposition by means of a variety of processes. The low molecular weight species produced recombine under controlled conditions to generate synthetic fuels. However, an important fraction undergo further recombination into higher molecular weight components, leading to the formation of coke. The optical texture of the coke can be related to its originating components. Those with high sulfur and oxygen content tend to produce cokes with small optical texture or fine mosaic, whereas compounds with relatively high hydrogen content are likely to produce large optical texture or domains. In addition, the structure of the parent chemical components, planar or nonplanar, determines the isotropic or anisotropic character of the coke. Planar molecules have a tendency to align in an approximately parallel arrangement to initiate the formation of the nematic mesophase leading to the formation of anisotropic coke. Nonplanar highly alkylated compounds and/or those rich in polar groups form isotropic coke. The aliphatic branches produce steric hindrance to alignment, whereas the polar groups participate in cross-linking reactions.

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TEM observation of iron oxide pillars in montmorillonite

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100177544 ◽

1990 ◽

Vol 48 (4) ◽

pp. 882-883

Author(s):

H. Mori ◽

Y. Murata ◽

H. Yoneyama ◽

H. Fujita

Keyword(s):

Aqueous Solution ◽

Iron Oxide ◽

Fine Particles ◽

Aqueous Suspension ◽

Volume Ratio ◽

Exchange Capacity ◽

Nano Composites ◽

Pillared Montmorillonite ◽

Topographic Features ◽

Transmission Electron

Recently, a new sort of nano-composites has been prepared by incorporating such fine particles as metal oxide microcrystallites and organic polymers into the interlayer space of montmorillonite. Owing to their extremely large specific surface area, the nano-composites are finding wide application[1∼3]. However, the topographic features of the microstructures have not been elucidated as yet In the present work, the microstructures of iron oxide-pillared montmorillonite have been investigated by high-resolution transmission electron microscopy.Iron oxide-pillared montmorillonite was prepared through the procedure essentially the same as that reported by Yamanaka et al. Firstly, 0.125 M aqueous solution of trinuclear acetato-hydroxo iron(III) nitrate, [Fe3(OCOCH3)7 OH.2H2O]NO3, was prepared and then the solution was mixed with an aqueous suspension of 1 wt% clay by continuously stirring at 308 K. The final volume ratio of the latter aqueous solution to the former was 0.4. The clay used was sodium montmorillonite (Kunimine Industrial Co.), having a cation exchange capacity of 100 mequiv/100g. The montmorillonite in the mixed suspension was then centrifuged, followed by washing with deionized water. The washed samples were spread on glass plates, air dried, and then annealed at 673 K for 72 ks in air. The resultant film products were approximately 20 μm in thickness and brown in color.

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Single-peak-regulation and wide-angle dual-band metamaterial absorber based on hollow-cross and solid-cross resonators

The European Physical Journal Applied Physics ◽

10.1051/epjap/2020200145 ◽

2020 ◽

Vol 91 (3) ◽

pp. 30901

Author(s):

Yibo Tang ◽

Longhui He ◽

Jianming Xu ◽

Hailang He ◽

Yuhan Li ◽

...

Keyword(s):

Transverse Electric ◽

Surface Current ◽

Dielectric Substrate ◽

Transverse Magnetic ◽

Metamaterial Absorber ◽

Absorption Peak ◽

Dual Band ◽

Single Peak ◽

Wide Angle ◽

Surface Current Density

A dual-band microwave metamaterial absorber with single-peak regulation and wide-angle absorption has been proposed and illustrated. The designed metamaterial absorber is consisted of hollow-cross resonators, solid-cross resonators, dielectric substrate and metallic background plane. Strong absorption peak coefficients of 99.92% and 99.55% are achieved at 8.42 and 11.31 GHz, respectively, which is basically consistent with the experimental results. Surface current density and changing material properties are employed to illustrate the absorptive mechanism. More importantly, the proposed dual-band metamaterial absorber has the adjustable property of single absorption peak and could operate well at wide incidence angles for both transverse electric (TE) and transverse magnetic (TM) waves. Research results could provide and enrich instructive guidances for realizing a single-peak-regulation and wide-angle dual-band metamaterial absorber.

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