scholarly journals Exploring factors associated with research involvement of undergraduate students at the College of Medicine and Health Sciences, University of Rwanda

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Eric Mugabo ◽  
Lotta Velin ◽  
Richard Nduwayezu
Keyword(s):  
Undergraduate Students ◽  
Undergraduate Research ◽  
Research Participation ◽  
Health Sciences ◽  
Mean Value ◽  
Sub Saharan Africa ◽  
Research Support ◽  
Factors Associated ◽  
Research Involvement ◽  
The Mean

Abstract Background Early involvement of students in research processes is an important step in professional development and can increase the academic output of the university. Previous studies indicate low research involvement amongst undergraduate students, however limited research has been done in sub-Saharan Africa. This study aimed to describe the level of research involvement amongst undergraduate students at the College of Medicine and Health Sciences (CMHS) at University of Rwanda (UR) and to assess factors associated with research involvement. Methods This cross-sectional study covered the three CMHS campuses. A survey was shared in class WhatsApp groups from July to September 2020. Data were analyzed using Stata IC 16.0 with descriptive statistics and Fisher’s exact test. P-values < 0.05 were considered statistically significant. Results In total, 324 students participated with the mean age being 23.3 (standard deviation 2.27). Males constituted 65.1% of respondents vs. 33.3% females. The largest portion of respondents were from the School of Medicine and Pharmacy (46.6%), and Medicine was the most frequent department (33.3%). On a Likert scale from 1 to 10, 60.0% of the respondents thought that research was 10/10 important for undergraduate students, with the mean value being 8.8. Rating their interest in taking part in research during undergraduate studies, 48.2% scored it 10/10, with the mean value being 8.57. 80.3% of respondents had attended a research module, course, or workshop; however, only 48.8% had participated in a research project and 72.0% of them had been involved in data collection. Inadequate knowledge about research processes and lack of mentors were the main barriers to research participation in 48.0 and 40.2% of respondents respectively. Establishment of a UR-Undergraduate research support center (77.2%), and involving students in ongoing UR projects (69.4%) were the most frequent suggestions to improve students’ research participation. Conclusion Undergraduate students at the CMHS in the UR have a large research interest, yet their involvement is currently low. Limited knowledge about research processes and shortage of mentors remains potent barriers to participation. Inviting undergraduate students to partake in ongoing projects and establishing a UR undergraduate research support center are recommended to strengthen undergraduate research experience at the UR-CMHS.

scholarly journals POS1430 EPIDEMIOLOGY OF LUPUS NEPHRITIS IN BRAZIL: FINDINGS FROM THE MACUNAÍMA STUDY - A NATIONWIDE MULTICENTRIC STUDY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 999.1-999
Author(s):  
M. Abreu ◽  
O. Monticielo ◽  
V. Fernandes ◽  
A. Cristovão Maiorano ◽  
F. Dos Santos Beserra ◽  
...  
Keyword(s):  
Lupus Nephritis ◽  
Disease Activity ◽  
Systemic Lupus ◽  
Research Support ◽  
Multicentric Study ◽  
Factors Associated ◽  
Type Iv ◽  
Damage Accrual ◽  
History Of ◽  
The Mean

Background:Lupus nephritis (LN) is one of the most serious organic manifestations of systemic lupus erythematosus (SLE). Ethnicity can contribute to disparities in the prevalence and disease activity of LN.Objectives:To assess the prevalence of LN in Brazilian patients with SLE and to determine factors associated with LN activity across the country.Methods:This cross-sectional study (GSK Study 207353) was carried out through face-to-face interviews and review of medical records (12-month study period). Adult patients with SLE (American College of Rheumatology [ACR] criteria, 1997) were included. Five SLE reference teaching centres were selected: North (NO), Northeast (NE), Midwest (CO), Southeast (SE), and South (SU). Patients with another disease whose morbidity surpassed SLE were excluded. LN was defined as reported in the medical record or history of confirmed renal biopsy; disease activity by pre-defined changes in SLE Disease Activity Index (SLEDAI) or the patient’s kidney disease during the study. Activity was assessed during (T0), 6 months before (T6), and 12 months before (T12) the interview. Systemic Lupus International Collaborating Clinics/ACR Damage Index score mapped damage accrual. Two pairings were performed, aiming to discriminate factors associated with LN and its activity, respectively. Matching technique was used to select similar individuals based on propensity scores, obtained from a logistic regression model. A bootstrapping method explored characteristic variables associated with the risk of progressing to LN.Results:Overall, 300 Brazilian patients with SLE were included in the study. Two groups were paired: LN group (N=150) and non-LN group (N = 141). The prevalence of LN in the paired sample (N=291) was 51.5%, with a disparity between centres (p<0.001; Figure 1A). Most patients were female (LN: 92.7%; non-LN: 94.3%) and the mean (standard deviation [SD]) age for the LN and non-LN groups was 39.46 (11.86) and 43.96 (12.18), respectively. History of serositis was associated with the presence of LN (42 [28.0%] vs 21 [14.9%] non-LN; p=0.010). Type IV histological class predominated in both groups, with no disparity between centres. Social disparities were noted between groups. Non-active workers prevailed among the LN group (115 [76.7%] vs 98 [69.5%] for non-LN, p=0.024).When pairing for disease activity at T12, 73 (50.3%) patients with LN (N=145) had active disease. There was regional disparity in terms of disease activity (Figure 1B), with a predominance of active LN in the NO (28 [68.3%]) and SU (16 [55.2%], p=0.026). Type IV histological class was the component most associated with active LN (active: 32 [43.8%]; non-active: 11 [15.3%], p<0.001). Variation in SLEDAI during the study period discriminated between active and non-active LN. The mean (SD) SLEDAI score at T12 was substantially higher in those with active LN compared with non-active LN (7.18 [4.83] vs 2.47 [4.63], p<0.001). As for the pattern of care, corticosteroids users prevailed in those with active LN (62 [84.9%] vs 45 [62.5%] for non-active LN, p=0.004). There was no disparity in the use of immunosuppressants, with the exception of cyclophosphamide use, noted among 16 (21.9%) patients with active LN and 6 (8.3%) patients with non-active LN (p=0.041). Psychotropic or anticonvulsant use was higher in patients with non-active LN (32 [44.4%] vs 17 [23.3%] patients with active LN, p=0.012). Consultation with a neurologist was verified in 15 (20.8%) patients with non-active LN and 6 (8.2%) with active LN (p=0.055). Hospitalisation occurred in 17 patients with non-active (23.6%) and active (23.3%) LN.Conclusion:Disparities in the prevalence of LN and its activity were evident between the regions across Brazil, highlighting differences in clinical factors, regional factors, and patterns of care.Funding:GSKFigure 1.Prevalence of A) LN among regional centres, comparing them to disease activity profile and prescriptive practice, and B) Active and non-active LN according to prescriptive practiceCQ, chloroquine; HCQ, hydroxychloroquine*At T12Acknowledgements:Medical writing assistance was provided by Helen Taylor, Fishawack Indicia Ltd., UK, part of Fishawack Health, and was funded by GSK.Disclosure of Interests:Mirhelen Abreu Grant/research support from: GSK, Amgen, Biogen, Libbs, Odirlei Monticielo Speakers bureau: GSK, AbbVie, UCB, Roche, Novartis, Consultant of: GSK, AbbVie, Janssen, Vander Fernandes Speakers bureau: Janssen, Novartis, Roche, AbbVie, Pfizer, Grant/research support from: Novartis, GSK, Pfizer, Alexandre Cristovão Maiorano: None declared, Fernando dos Santos Beserra: None declared, Flavia Lamarao Employee of: GSK, Nathalie David Shareholder of: GSK, Employee of: GSK, Bruna de Veras Employee of: GSK, Blanca Bica: None declared, Domingos Sávio Nunes de Lima Grant/research support from: GSK, Marta Maria das Chagas Medeiros: None declared

A Study of Mechanical Engineering Students’ Learning Outcomes During Summer Undergraduate Research Experiences

2008 ◽  
Author(s):  
Olga Pierrakos
Keyword(s):  
Undergraduate Students ◽  
Engineering Students ◽  
Undergraduate Research ◽  
Evaluation Studies ◽  
Research Participation ◽  
Thinking Skills ◽  
Research Experiences ◽  
Great Opportunity ◽  
Problem Solving Skills ◽  
Undergraduate Research Experiences

Undergraduate research experiences, which are highly promoted and supported by NSF and other agencies, present a great opportunity for our students to learn essential problem solving skills. The National Science Foundation’s Research Experiences for Undergraduates (REU) program is one of the largest initiatives supporting active research participation by undergraduate students in all of the areas of research funded by NSF. The REU program, with more than 600 sites around the world, presently funds over 1000 active awards, totaling over $327 million. From these active REU awards, 384 (38% of the total active awards) are related to engineering (determined by having ‘engineering’ as a keyword in the title and abstract) and account for about $170 million, about half of the total amount of awards to date. In spite of such widespread support and belief in the value of undergraduate research, limited well-grounded research and evaluation studies exist [1]. Most of the existing literature reveals the predominance of program descriptions, explanation of models, and evaluation efforts, rather than studies grounded on research. Only recently have research and evaluation studies focused on assessing the benefits of undergraduate research [1–8]. Some of these benefits are (a) retention for underrepresented groups, (b) increased interest in the discipline, (c) gaining critical thinking skills, (d) increased self-confidence, and (e) clarification of career goals. Moreover, most of these studies on undergraduate research have focused on the sciences, whereas undergraduate research experiences in engineering have been understudied.

Extending the Reach of the STARs (Students Tackling Advanced Research)

2021 ◽  
pp. 009862832110560
Author(s):  
Caitlin Posillico ◽  
Sarah Stilwell ◽  
Jacqueline Quigley ◽  
Crystal Carr ◽  
Sara Chadwick ◽  
...  
Keyword(s):  
Undergraduate Students ◽  
Low Income ◽  
Undergraduate Research ◽  
Underrepresented Students ◽  
Research Participation ◽  
Research Process ◽  
Self Report ◽  
Educational Outreach ◽  
Outreach Program ◽  
Research Opportunities

Background Participating in research opportunities during undergraduate education is met with myriad benefits. Students learn the scientific research process, how to think critically, develop transferable skills, refine public speaking, build a professional network, and gain confidence. Despite the numerous benefits of undergraduate research participation, underrepresented and minority (URM) students (e.g., first-generation, low-income, and historically underrepresented students) often do not engage in these valuable undergraduate research opportunities. Objective To begin breaking down some of these historical barriers to participation, we developed the Students Tackling Advanced Research (STAR) Scholars Program. Method A holistic educational outreach program was designed to facilitate underrepresented undergraduate students’ involvement in research and help them understand why research is important in a greater context. Conclusion Students who participated in STAR Scholars self-report positive impacts on understanding what research is, ways to seek out research opportunities, and what steps to take toward future educational and professional goals. Teaching Implications It is imperative to explicitly target barriers that underrepresented students face to allow for equity and inclusion in research and academia. Workshops and activities designed to demystify research, build networking and professional skills, and provide mentorship to students are successful in breaking down these barriers and increase student confidence and competence.

scholarly journals 2D-shear wave elastography: number of acquisitions can be reduced according to clinical setting

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Marco Dioguardi Burgio ◽  
Jules Grégory ◽  
Maxime Ronot ◽  
Riccardo Sartoris ◽  
Gilles Chatellier ◽  
...  
Keyword(s):  
Shear Wave ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Mean Value ◽  
Factors Affecting ◽  
Absolute Value ◽  
Factors Associated ◽  
Supersonic Shear Imaging ◽  
The Mean ◽  
The Difference

Abstract Background The factors affecting intra-operator variability of two-dimensional shear wave elastography (2D-SWE) have not been clearly established. We evaluated 2D-SWE variability according to the number of measurements, clinical and laboratory features, and liver stiffness measurements (LSM). Methods At least three LSM were performed in 452 patients who underwent LSM by 2D-SWE (supersonic shear imaging) out of an initial database of 1650 patients. The mean value of the three LSM was our best measurement method. Bland–Altman plots were used to evaluate intra-operator variability when considering only one, or the first two measurements. Variability was assessed by taking the absolute value of the difference between the first LSM and the mean of the three LSM. Logistic regression was used to assess the factors associated with the highest tertile of variability. Results The limit of agreement was narrower with the mean of the first and second measurements than with each measurement taken separately (− 2.83 to 2.99 kPa vs. − 5.86 to 6.21 kPa and − 5.77 to 5.73 kPa for the first and second measurement, respectively). A BMI ≥ 25 kg/m2 and a first LSM by 2D-SWE ≥ 7.1 kPa increased the odds of higher variability by 3.4 and 3.9, respectively. Adding a second LSM didn’t change the variability in patients with BMI < 25 and a first LSM by 2D-SWE < 7.1 kPa. Conclusions Intra-operator variability of LSM by 2D-SWE increases with both a high BMI and high LSM value. In patients with BMI < 25 kg/m2 and a first LSM < 7.1 kPa we recommend performing only one LSM.

scholarly journals PREDISPOSING-PERSONAL FACTORS ASSOCIATED WITH PASSENGERSAFETY AND SAFE RIDINGBEHAVIORS AMONG CYCLISTS (BODA BODA RIDERS) IN KAMPALA

2021 ◽  
Vol 9 (07) ◽  
pp. 497-506
Author(s):  
Afolabi I.B ◽  
◽  
Mansir B.A ◽  
Abdullahi L.A ◽  
Aremu A.B ◽  
...  
Keyword(s):  
Educational Attainment ◽  
Road Traffic ◽  
Sub Saharan Africa ◽  
Public Health Issue ◽  
Personal Factors ◽  
Cross Sectional Survey ◽  
Factors Associated ◽  
Reference Scale ◽  
Passenger Safety ◽  
The Mean

Background: Motorcycle taxis are common means of transportation in Uganda and sub-Saharan Africa which remains a major neglected public health issue that presently at any time constitutes risk for road traffic accident and injuries in low and middle income countries. This study describes the level of predisposing-personal factors associated with passenger safety and safe riding behaviors among cyclists (bodabodariders) in Kampala and the relationship between age, educational attainment and the risk of road accident. Methodology:The study design was a cross-sectional survey using a validated semi-standard questionnaire to collect data on predisposing-personal factors and safe riding behaviors measured on a 31 and 24-point reference scale respectively from 422 consenting riders in the metropolis. Data from the study was analyzed using statistical package for social sciences (SPSS) and simple descriptive statistics such as means, standard deviations, and proportions were used to describe the data all in 95% confidence interval and Analysis of variance was employed to test differences in measures across age and level of education with a cut-off set at (p≤0.05) significance level. Results: The findings showed thatmajority of the respondents were between age of 25 and 29 (35.5%) where most of them (36.0%) had secondary educational attainment. The mean score for the level of predisposing-personal factors measured on a 31-point reference scale among respondents in our study was 23.9 (CI =23.60 ± 24.20) denoting a prevalence of 77.1%while the mean score for the safe riding behaviors as measured on 24-pointscale was 9.3 (CI =9.10 ± 9.60) which translates to prevalence of 38.8%. The study further revealed that older respondents and riders with non-formal education inconsistently reported lowest scorefor predisposing-personal factors (F=3.54, p=0.007 and F=14.49, p<0.0001), whereas older respondents and riders with tertiary educational attainment constantly displayed lowest scores for safe riding behaviours (F=14.86, p<0.0001 and F=7.15, p<0.0001). Conclusions: The level of predisposing-personal factors associated with road safety and safe riding in terms of knowledge about passenger safety, perception of risk on road accidents and health consequences as well as attitudes toward safety rules and safe riding among respondents in the study is relatively high but the level of their safe riding behaviors is low and quite unsatisfactory.Thus, this calls for education and training exercises by the regulatory agencies on the initiation of safe riding behaviorsamong riders for knowledge without practice is useless.

scholarly journals Classical path from quantum motion for a particle in a transparent box

2014 ◽  
Vol 36 (2) ◽  
Author(s):  
Salvatore De Vincenzo
Keyword(s):  
Undergraduate Students ◽  
Free Particle ◽  
Mean Value ◽  
Position Operator ◽  
One Dimensional ◽  
Quantum Numbers ◽  
Classical Path ◽  
The Mean ◽  
Basic Ideas ◽  
Quantum Motion

We consider the problem of a free particle inside a one-dimensional box with transparent walls (or equivalently, along a circle with a constant speed) and discuss the classical and quantum descriptions of the problem. After calculating the mean value of the position operator in a time-dependent normalized complex general state and the Fourier series of the function position, we explicitly prove that these two quantities are in accordance by (essentially) imposing the approximation of high principal quantum numbers on the mean value. The presentation is accessible to advanced undergraduate students with a knowledge of the basic ideas of quantum mechanics.

scholarly journals 838. Drivers of empiric carbapenem use: How important is history of extended-spectrum beta-lactamase (ESBL) infection?

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S460-S460
Author(s):  
Tyler J Stone ◽  
James Beardsley ◽  
James Johnson ◽  
Christopher Ohl ◽  
Christopher Ohl ◽  
...  
Keyword(s):  
Risk Factors ◽  
Univariate Analysis ◽  
Research Support ◽  
Factors Associated ◽  
Negative Culture ◽  
Increased Risk ◽  
Culture Characteristics ◽  
The Mean ◽  
Culture Positive ◽  
Research Grant

Abstract Background CARs are first line agents for serious infections caused by ESBL producers. Likelihood of developing subsequent ESBL infection is unknown. In patients (pts) with a history (hx) of ESBL positive (ESBLP) culture, empiric therapy with a CAR has become common in hospitals. The purpose of this study was to evaluate the microbiology of subsequent infections (SI) among pts with hx of ESBLP culture and determine risk factors associated with ESBLP SI that may justify an empiric CAR. Methods This retrospective observational study was conducted at a multicenter health system. The electronic medical record (EMR) was used to generate a report of all E. coli (EC) or K. pneumoniae (KP) ESBLP cultures during 2017, an analogous report was generated for ESBL-negative (ESBLN) EC or KP. These were termed index cultures (IC). Pts were randomly selected from each report until 200 total pts were enrolled. Inpatients, outpatients, and all culture specimens were included. Pts with an ESBLP culture prior to 2017 were excluded. The EMR was reviewed up to 1 year after the IC. Pt and culture characteristics were recorded. The primary outcome was proportion of pts who developed an ESBLP SI. Risk factors associated with ESBLP SI were determined. Relapsed infection (same site, same bacteria) that occurred within 2 weeks of the IC was excluded. Results 200 pts were included, 100 with ESBLP IC and 100 with ESBLN IC. The mean age was 58 years, 84% were female, and 69% were outpatients. 86% of IC were EC and 86% were urine specimens. Within 1 year of IC, 100 pts (50%) developed a SI. 22 of these were ESBLP, 43 were ESBLN, and 35 had no or negative culture. The mean time since IC for ESBLP SI and ESBLN SI was 85 (26-226) days and 140 (15-363) days, respectively (p=0.014). When comparing time to SI, 21 (96%) ESBLP and 26 (61%) ESBLN occurred &lt; 6 months after IC (p=0.003). Among SI with culture data (n= 65), the number of ESBLP SI was higher if the IC was ESBLP (22 vs 0, p&lt; 0.001). Incidence of ESBLP or ESBLN SI in all pts with an ESBLP IC was similar (22 vs 18, p=0.428). Factors associated with ESBLP SI were hx of ESBLP IC, male gender, and time between IC and SI. Table 1. Index Culture Characteristics of Culture Positive Subsequent Infections Figure 1. Cumulative rate of ESBL-positive SI in 180 days (6 months) following IC Table 2. Univariate Analysis of Patient Characteristics Comparing ESBL-positive and ESBL-negative Culture Positive Subsequent Infections Conclusion Hx of positive culture for ESBL-producing EC or KP is associated with SI caused by ESBLP EC or KP. Pts presenting &lt; 6 months after ESBLP IC are at increased risk for ESBLP SI, justifying empiric CAR therapy. Disclosures Tyler J. Stone, PharmD, Paratek (Research Grant or Support) Elizabeth Palavecino, MD, Paratek (Grant/Research Support)Paratek (Grant/Research Support) John Williamson, PharmD, Paratek (Research Grant or Support)

scholarly journals Association of academic stress & performance in continuous assessment among pharmacy students in body system course

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
May Khin Soe ◽  
Mohamad Sharul Fahmi Baharudin
Keyword(s):  
Undergraduate Students ◽  
Time Management ◽  
Mean Value ◽  
Pharmacy Students ◽  
Body System ◽  
Continuous Assessment ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean ◽  
Whole Class

Introduction: Undergraduate Pharmacy students find the program is stressful. This study compares the perceived stress score (PSS) of third year Pharmacy students and their performance via continuous assessment (CAM) in a body system course. Methods: The relationship between the PSS and their academic performance, though out the semester were explored for 114 students including 25 male and 85 female. In this cross-sectional study, questionnaires were distributed to assess their PSS, other relevant questions and the result in four quizzes on the course were recorded periodically and analyzed descriptively. Results: The mean value of the whole class PSS score was found (38.66 ± 6.46). Females’ PSS in 1st quiz was 38.76 ± 5.56 and male’s was 39.21 ± 5.48 and quiz 2 for female was 38.61 ± 6.27 whereas 40.1 ± 7.48 in male. That value in quiz 3 and 4 for female was 38.10 ± 7.18 and male was 39.69± 8.68. However, there is no significant difference in gender. The PSS score for all participants was found highest in the second quiz (38.99 ± 6.60) whereas the mean marks they obtained were lowest (4.97 ± 1.36) compared to other quizzes but their relation is weakly significant. Total scoring of the CAM for the whole class was found even lower compared to previous batches, 23.83 ± 3.88. They were engaged with various co-curriculum activities and complained of not having enough time to study and revise. The unsatisfactory performance might be due to heavy topics and time constraint. Conclusions: Stress and time management are critical elements for undergraduate students to perform well academically regardless of their stress level.

scholarly journals SAT0472 GOAL-DIRECTED TREATMENT OF OSTEOPOROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS USING DENOSUMAB FOR FIVE YEARS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1193.1-1193
Author(s):  
Y. Hirano ◽  
Y. Kanayama ◽  
H. Kosugiyama ◽  
N. Ishiguro ◽  
T. Kojima
Keyword(s):  
Rheumatoid Arthritis ◽  
Working Group ◽  
Mean Value ◽  
Treatment Goal ◽  
Research Support ◽  
Mineral Research ◽  
Female Patients ◽  
T Score ◽  
Tracp 5B ◽  
The Mean

Background:Osteoporosis (OP) is frequent complication identified in patients with rheumatoid arthritis (RA). Effective treatment must be provided to treat OP in RA (RAOP). Denosumab (DMB) is one of the promising drugs that are currently being used for the treatment of RAOP. We reported the results of 12-month DMB treatment for RAOP as part of Japanese multicenter registry study (TBCR-BONE) in EULAR2016 [1]. Recently, a treatment goal of OP was reported by the American Society for Bone and Mineral Research and the National Osteoporosis Foundation (ASBMR-NOF) working group [2]. This report advocated that the goal of treatment is a T-score of >-2.5 at the femoral neck, total hip (TH) or lumbar spine (LS) on DXA if the primary reason for starting treatment was a T-score of ≤-2.5 at the abovementioned skeletal sites. The working group noted that it was reasonable to expect that initial treatment should offer at least a 50% chance of achieving the treatment goal within 3 to 5 years of initiating therapy. We have reported the achievement rates of treatment goal in RAOP with 3-year DMB treatment on RAOP in EULAR2019 [3].Objectives:The aim of this retrospective study was to evaluate whether 5-year DMB treatment can achieve treatment goal of OP using data from TBCR-BONE.Methods:The study included 46 female patients who had completed 5-year DMB treatment. The LS-BMD analysis included 22 patients with a baseline (BL) LS-BMD T-score of ≤ -2.5. The TH-BMD analysis included 29 patients with a BL TH-BMD T-score of ≤ -2.5. Similar to clinical setting in Japan, 60mg of DMB was administered once every 6 months with a vitamin D3 supplement. BL characteristics, change in T-score over time, and achievement of the treatment goal (T-score>-2.5) were evaluated.Results:BL characteristics of the 46 female patients included: mean age of 69.1 years and RA duration of 16 years. Prednisolone was administered to 37% of the patients. In the LS-BMD analysis, T-scores improved significantly; the mean value at BL was −3.4, which increased to −3.0 at 1 year, −2.6 at 3 years, and ultimately to −2.5 at 5 years. The fraction of patients who achieved the treatment goal was as follows: 36.4% at 1 year, 40.9% at 2 years, 45.5% at 3 years, 50.0% at 4 years, and 54.5% at 5 years (Fig. 1A). The patients who achieved this treatment goal were those who had a significantly lower risk of fracture at BL as determined by FRAX (17.9% vs. 32.2%, p = 0.044), who had significantly higher BL serum TRACP-5b level (572.8 vs. 401.0: p = 0.03), and who had significantly better BL LS-BMD T-scores (−3.0 vs. −3.9, p < 0.01) than the nonachievers. In the TH-BMD analysis, T-scores improved significantly; the mean value at BL was −3.0, and it increased to −3.0 at 1 year, −2.7 at 3 years, and reached −2.7 at 5 years. The fraction of patients who achieved the treatment goal was as follows: 20.7% at 1 year, 31.0% at 2 years, 34.5% at 3 years, 31.0% at 4 years, and 37.9% at 5 years (Fig. 1B). The patients who achieved this treatment goal were those who had significantly better BL TH-BMD T-scores (−2.7 vs. −3.2: p < 0.01) than the nonachievers. Cut-off values at BL for achievement of the treatment goal determined using ROC analysis were −3.1 for the LS-BMD (sensitivity 83.3%, specificity 90.0%) and −2.85 for the TH-BMD (sensitivity 100.0%, specificity 81.0%).Conclusion:The results of this study suggested that achievement of the treatment goal was comparatively easy for those with LS-BMD loss; however, it was comparatively difficult for those with TH-BMD loss. Early initiation or longer duration of DMB therapy may be necessary to improve achievement rates. Likewise, other agents, such as romosozumab, may be considered for those with significant TH-BMD loss.References:[1]Hiranoet al.Ann Rheum Dis 2016; 75 (Suppl 2): 94[2]Cummingset al.J Bone Miner Res 2017; 32: 3-10[3]Hiranoet al.Ann Rheum Dis 2019; 78 (Suppl 2): A940Disclosure of Interests:Yuji Hirano Speakers bureau: Tanabe-Mitsubishi, Pfizer, Eisai, Abbie, Chugai, Bristol-Meyers, Jansen, Astellas, UCB, Eli-Lilly, Asahikasei, Daiichi-Sankyo, Amgen, Yasuhide Kanayama: None declared, Hironobu Kosugiyama: None declared, Naoki Ishiguro Grant/research support from: AbbVie, Asahi Kasei, Astellas, Chugai, Daiichi-Sankyo, Eisai, Kaken, Mitsubishi Tanabe, Otsuka, Pfizer, Takeda, and Zimmer Biomet, Consultant of: Ono, Speakers bureau: Astellas, Bristol-Myers Squibb, Daiichi-Sankyo, Eli Lilly, Pfizer, and Taisho Toyama, Toshihisa Kojima Grant/research support from: Chugai, Eli Lilly, Astellas, Abbvie, and Novartis, Consultant of: AbbVie, Speakers bureau: AbbVie, Astellas, Bristol-Myers Squibb, Chugai, Daiichi-Sankyo, Eli Lilly, Janssen, Mitsubishi Tanabe, Pfizer, and Takeda

scholarly journals Assessment of Level of HIV/AIDS Preventive Self-Efficacy and Associated Factors Among Regular Undergraduate Students of Madda Walabu University, Southeast Ethiopia, 2020. A Cross-Sectional Study

2020 ◽  
Author(s):  
Chala Kene ◽  
Haweni Adugna ◽  
Kalkidan Lemessa ◽  
Leul Deribe
Keyword(s):  
Undergraduate Students ◽  
Self Efficacy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Drinking Alcohol ◽  
Cross Sectional ◽  
Factors Associated ◽  
Southeast Ethiopia ◽  
The Mean ◽  
Hiv Aids

Abstract Background: Self-efficacy for HIV prevention is described as a person’s belief in his/her capacity to carry out necessary actions to perform a specific behavior for HIV prevention. This study aimed to assess level of HIV/AIDS preventive self-efficacy and associated factors among regular undergraduate students of Madda Walabu University, Southeast Ethiopia, 2020. Methods: Cross-sectional study was conducted from February 15 to 20, 2020. Four hundred forty-two study participants were selected using simple random sampling technique. Data was entered to Epi Data version 4.6.0.2 and analyzed using SPSS version 26 software. Bivariate and multivariable logistic regression model was fitted to identify factors associated with HIV/AIDS preventive self-efficacy. Odds ratio with 95% confidence interval was computed and p value less than 0.05 was used to determine the level of significance. Result: The mean level of HIV/AIDS preventive self-efficacy among regular undergraduate students of Madda Walabu University was found to be 74.58+19.98. Being female [AOR=1.76(1.04-2.81)], in field of health science [AOR= 1.92(1.10-3.36)], second year of study [AOR=2.77(1.55-4.94)] and drinking alcohol [AOR=2.9(1.61- 5.23)] were found to be factors associated with higher HIV/AIDS preventive self-efficacy. Whereas, exposed to pornography [AOR=0.53(0.33-0.85)] was found to be factor associated with lower HIV/AIDS preventive self-efficacy.Conclusion: The mean HIV /AIDS preventive self-efficacy of the participants in this study area were found to be low. Sex, field and year of study, drinking alcohol and ever had watched pornography were factors found to be significantly associated with HIV/AIDS preventive self-efficacy. Staffs should be cooperative in educating their students to boost their self-efficacy.

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