scholarly journals Clinical, laboratory and ultrasonographic findings in 38 calves with type-4 abomasal ulcer

2021 ◽  
Vol 63 (1) ◽  
Author(s):  
Ueli Braun ◽  
Christina Widmer ◽  
Karl Nuss ◽  
Monika Hilbe ◽  
Christian Gerspach

Abstract Background Type-4 abomasal ulcers (U4) are perforated ulcers causing diffuse peritonitis. This retrospective study describes the clinical, laboratory and ultrasonographic findings in 38 calves with U4. The medical records of 38 calves aged three days to 20 weeks with U4 were scrutinised. Results The most common clinical findings were poor general health (95%), reduced skin elasticity (95%), rumen atony (91%), abdominal guarding (76%) and positive percussion auscultation and/or swinging auscultation on the right side of the abdomen (75%). The most frequent laboratory findings were increased numbers of segmented neutrophils (87%), eosinopenia (87%), acidosis (84%), azotaemia (79%) and hyponatraemia (79%). The most frequent abdominal ultrasonographic findings were intestinal atony (68%), fluid (67%) and fibrin deposits (58%) in the abdomen. Thirty-five calves were euthanased and three calves died spontaneously. All calves underwent pathological examination. Diffuse peritonitis caused by a transmural abomasal ulcer was the principal diagnosis in all calves. Conclusions Perforated abomasal ulcers cause severe illness, and a thorough clinical examination combined with ultrasonographic abdominal examination should lead to a tentative diagnosis.

2020 ◽  
Vol 24 (2) ◽  
pp. 146-157
Author(s):  
Sedigheh Hasani Moghadam ◽  
◽  
Abbas Alipour ◽  
Saeid Abedian Kenari ◽  
Soghra Khani ◽  
...  

The emerging Coronavirus (COVID-19) is a new infectious disease and the definitive gold standard for its diagnosis in pregnancy has not yet been established. Therefore, this study was conducted with the aim of reviewing the diagnostic methods and clinical, laboratory and radiological symptoms of COVID-19 disease in pregnant women. The present study is a Narrative review. To do so, the keywords were searched in the Scopus, Google scholar, PubMed, Embase, Science Direct, WHO databases from April 1, 2020 to May 9, 2020. 34 articles were obtained and finally 6 articles were used to write this study. Evidence related to the purpose of this study was identified in three categories. The first category examines clinical findings (fever and cough), the second category examines laboratory findings (leukocytosis and lymphopenia), and a third category examines chest radiographic findings (Pure ground-glass opacity). Since infection is one of the most important causes of death in pregnant women and is one of the preventable and controllable factors, so by identifying the correct diagnostic methods of this infection, at-risk pregnant women will be identified and Prevent the consequences of this infection.


2005 ◽  
Vol 134 (4) ◽  
pp. 894-901 ◽  
Author(s):  
K. MURRAY-LILLIBRIDGE ◽  
J. BARRY ◽  
S. REAGAN ◽  
D. O'FLANAGAN ◽  
G. SAYERS ◽  
...  

In May 2000, public health authorities in Dublin, Ireland, identified a cluster of unexplained severe illness among injecting drug users (IDUs). Similar clusters were also reported in Scotland and England. Concurrent investigations were undertaken to identify the aetiology and source of the illnesses. In Dublin, 22 IDUs were identified with injection-site inflammation resulting in hospitalization or death; eight (36%) died. Common clinical findings among patients with severe systemic symptoms included leukaemoid reaction and cardiogenic shock. Seventeen (77%) patients reported injecting heroin intramuscularly in the 2 weeks before illness. Of 11 patients with adequate specimens available for testing, two (18%) were positive by 16S rDNA PCR for Clostridium novyi. Clinical and laboratory findings suggested that histotoxic Clostridia caused a subset of infections in these related clusters. Empiric treatment for infections among IDUs was optimized for anaerobic organisms, and outreach led to increased enrolment in methadone treatment in Dublin. Many unique legal, medical, and public health challenges were encountered during the investigation of this outbreak.


2021 ◽  
pp. 24-25
Author(s):  
piyush Ranjan ◽  
Pragya Pragya ◽  
Manish Manish

A mesentric cyst is a rare intra abdominal benign pathology. They are found in the mesentry of small bowel (66%) and large intestine (33%), usually in the right colon. Very few cases have been reported of tumours found in mesentry of descending colon, sigmoid or rectum. Mesentric cysts do not show classical clinical findings and are detected incidentally during imaging due to absent or non-specific clinical presentation or during management of one of their complications. Optimal surgical management requires complete excision of the lesions. Although they are invariably benign, a full laparotomy has been the conventional approach for resection, often via a large midline incision. The advantage of minimally invasive surgery has allowed resection of the cysts, without need for a full laparotomy, with the benefit of improved cosmetics, less postoperative pain, and shorter hospital stay. However, laparoscopy can be technically challenging with large intra abdominal cysts. This is mainly due to lack of intra abdominal space and poor ergonomics in relation to port placements with large cysts. We report the incident of a 44-year-old female. A USG and computed tomography scan followed to help diagnose the lesion as a cyst. She underwent laproscopic removal and the cyst was enucleated intact. Postoperative period was uneventful and pathological examination showed a benign mesentric cyst . Objectives of this study is to analyze our experience with emphasis on the presentation, management, and outcome. Laproscopy not only helps in diagnosing the site and origin of the mesentric cyst but also has a therapeutic role. Laproscopic treatment of mesentric cyst is a safe, preferred method of treatment and is a less-invasive surgical technique. Here, we present an unusual case of mesentric cyst arising from Ascending colon treated by laproscopic excision.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Muhittin Celik ◽  
Osman Akdeniz

Background: Nonketotic hyperglycinemia (NKH) is a rare metabolism disorder with autosomal recessive transmission. Newborn infants characteristically present with hypotonia, lethargy, convulsions, and apnea and are generally lost within the first year of life. Objectives: The aim of this study was to evaluate the clinical characteristics, laboratory findings, and short-term results of infants diagnosed with NKH. Methods: The retrospective study included 10 infants diagnosed with NKH between August 2013 and July 2020. The clinical characteristics, laboratory findings, treatment methods, and short-term outcomes of the patients were evaluated. Results: The age range of patients (50% males vs. 50% females) was 2 - 8 days on presentation. The complaints on presentation were decreased breastfeeding, lethargy, convulsions, hiccups, apnea, and respiratory problems. In the physical examination, significant hypotonia and reduced or absence of newborn reflexes were predominant. Mechanical ventilation (MV) was required for nine patients. The cerebral spinal fluid/serum glycine ratio was > 0.08 in all patients, with median value of 0.19 (range: 0.12 - 0.30). The presence of a burst suppression pattern on electroencephalography and an increase in the glycine peak in magnetic resonance spectroscopy were the supportive diagnostic findings. Mutation analysis was performed on one patient. Seizures resistant to treatment were controlled with levetiracetam in three patients and dextromethorphan in one patient. Conclusions: According to the results, the most common clinical findings in NKH were severe hypotonia, seizure, and encephalopathy. In some cases, with resistant seizures, levetiracetam was found to be effective.


2018 ◽  
Vol 37 (1) ◽  
pp. 25-29
Author(s):  
Madhusudan Saha ◽  
SAHM Mesbahul Islam ◽  
Irin Perveen ◽  
Nasrin Aktar ◽  
Kabir Ahmed ◽  
...  

Introduction: Abdominal tuberculosis is not uncommon in daily medical practice. This study was done focusing variable presentations of abdominal tuberculosis Material and methods: Data of consecutive patients diagnosed as abdominal tuberculosis were analyzed. Their epidemiological features, presentations, laboratory findings, and response to therapy were analysed. Result: Total 69 cases (male 43, 62.3%,and female 26, 37.7%), age ranging from 15 to 85 years (mean 36.23) were enrolled. Rural (55, 79.7%), poor (49,71%) and housewives (24, 34.8%) and people of 21-30 years age group (27, 39.1%) were more affected. Diagnosis was based on combinations of clinical, laboratory findings and therapeutic response. In this series 30 (43.5%), 23 (33.4%) and 12 (17.3%) were diagnosed as intestinal, peritoneal and disseminated tuberculosis respectively. Of them68 patients recovered with treatment. Five patients developed intestinal obstruction and one developed hepatitis and lost from follow up. Conclusion: Diagnosis of abdominal tuberculosis is by combinations of clinical findings, without gold standard method. In our series intestinal tuberculosis and peritoneal tuberculosis were common clinical types with weight loss and abdominal pain as common clinical symptoms. And outcome of Treatment of TB was excellent J Bangladesh Coll Phys Surg 2019; 37(1): 25-29  


Author(s):  
Le Dinh Vinh Phuc ◽  
Cao Ba Loi ◽  
Huynh Hong Quang ◽  
Le Duc Vinh ◽  
Cao Truong Sinh ◽  
...  

Background: Human toxocariasis is prevalent in many countries but this disease has been rarely reported from Vietnam. We aimed to investigate the clinical and laboratory findings and assess possible association between these findings in patients with toxocariasis in Vietnam. Methods: A prospectively study, between October 2017 and June 2019 was performed involving 120 toxocariasis patients at Medic Medical Center, Ho Chi Minh City, Vietnam. The diagnosis of toxocariasis was established based on clinical, laboratory (eosinophilia, raised IgE concentration) and serological (positive Toxocara IgG ELISA test) evaluation as well as the exclusion of other helminthic coinfection.   Results: The most frequently reported manifestation was of skin (n = 93, 77.5%), including urticarial (n= 69, 57.5%) followed by neurologic, gastrointestinal and pulmonary signs/symptoms. Hepatic involvement occurred in 8.3% of the patients. No significant relationship between clinical findings and laboratory parameters was found except the higher values of eosinophil count and IgE concentration among patients with liver involvement. There was a significant relationship between eosinophil count and IgE concentration (r=0.389, P<0.001). Serological findings did not show a correlation with clinical and other laboratory findings. Conclusion: Our data revealed a wide range of clinical symptoms/signs and a high incidence of skin manifestations in patients with toxocariasis. Eosinophil count and IgE concentration are valuable markers for the evaluation of the disease.


2021 ◽  
Author(s):  
Felipe Fanine de Souza ◽  
Ana Luiza da Silva Wendhausen ◽  
Felipe Reinert Avilla Machado ◽  
Gustavo Figueiredo da Silva ◽  
Maria Eduarda Angelo de Mendonça Fileti ◽  
...  

Context: Non-ketotic hyperglycemia is a rare cause of chorea. Clinical findings are usually unilateral and potentially reversible after treatment for hyperglycemia. Hyperglycemia leads to asymmetric multifocal petechial hemorrhages of the basal ganglia, leading to a dysfunction of neuronal networks that connect the basal ganglia and the motor cortical areas, mainly affecting the subthalamic nucleus and contralateral striatum, which is highlighted by typical hyperdense lesions of the basal ganglia in computed tomography (CT) of the brain. This study aimed to report a case of a patient with choreiform movements due to a rare etiology of hyperglycemia nonketotic in a Hospital Public of Joinville, SC. The study was carried out through the collection and analysis of a patient’s medical record. Case report: Female patient, 54 years old, who presented for 6 days choreiform movements in the face, left upper limb and, discreetly, in the left lower limb. Snake tongue sign and milkmaid’s grip positive, without dysarthria. In the laboratory exam, glucose of 600 mg / dL; without further changes. Cranial tomography showed hyperdensity in the putamen region on the right. The treatment was started to obtain better glycemic control and Risperidone 3 mg / day. Conclusions: It is concluded, then, that non-ketotic hyperglycemia is an uncommon, but reversible cause of chorea, and may manifest itself due to an uncontrolled non-ketotic diabetes mellitus. Its pathogenic mechanism remains to be clarified. In addition, clinical, epidemiological, imaging and laboratory findings, together, corroborate for early diagnosis and proper management.


1996 ◽  
Vol 35 (04) ◽  
pp. 116-121 ◽  
Author(s):  
G. E Fueger ◽  
M. Vejda ◽  
R. M. Aigner

Summary Aim: To prevent orthopedic sequelae in acute hematogenous pyogenic osteomyelitis (AHPO) of infants early diagnosis, recognition of recurrence and effective therapy is needed. This retrospective study of 47 infants with bacteriologically confirmed AHPO concerned with an analysis of the diagnostic value of systemic serum parameters compared to bone scintigraphy (BSC). Methods: AHPO was characterized initially and during the course of disease by clinical findings, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), total and differential white blood cell (WBC) count, BSC, and plain radiography. Results: CRP was the most effective serum parameter for follow- up of disease. The first sign of BSC to signal adequate response to antibiotic treatment was the decrease or normalization of hyperperfusion. Escape from therapy or poor prognosis, even when the serum parameters were normalized, was signaled by the recurrence of focal hyperperfusion and the persistent or increasing local uptake ratios on the 3-h-image over 6 weeks during a course of antibiotic treatment. Conclusion: Antibiotic treatment masks the clinical presentation, and the radiographic findings, causes non-characteristic laboratory findings, but do not prevent the scintigraphic visualization; BSC and serum parameters used in the right completion are the most successful and efficient modalities for follow-up of AHPO. Maintenance of antibiotic therapy should be done until BSC findings have reverted to normal.


2018 ◽  
Vol 40 (4) ◽  
pp. 332-335
Author(s):  
P V Kuzyk ◽  
M A Savchyna ◽  
S G Gychka

Aim: To describe the case of rare benign lymphoproliferative disorder — pulmonary nodular lymphoid hyperplasia in the patient with previous pulmonary tuberculosis. Materials and Methods: In the case of pulmonary nodular lymphoid hyperplasia clinical, laboratory, instrumental and morphological examination was performed. Results: 44-year-old woman in 7 years after successfully treated infiltrative drug-susceptible tuberculosis of the right lung, was hospitalized with a suspected tumor of the left lung root. The patient underwent left-sided pneumonectomy with lymph nodes dissection. The results of histopathological and immunohistochemical studies evidenced on nodular lymphoid hyperplasia of the left lung. Conclusion: Pulmonary nodular lymphoid hyperplasia is a rare lymphoproliferative disorder of the lung with favorable prognosis. For the purpose of differential diagnosis, it is necessary to apply immunohistochemistry.


Author(s):  
Hamid Owaysee Osquee ◽  
Sepehr Taghizadeh ◽  
Mehdi Haghdoost ◽  
Hadi Pourjafar ◽  
Fereshteh Ansari

Introduction: In this article, we report data on confirmed CCHF cases from Iran and describe the association between studying factors and outcomes of the disease. Objective: Crimean Congo Hemorrhagic Fever (CCHF) is an acute and fatal disease with various clinical and paraclinical characteristics. Methods: In the Study design, we evaluated demographic characteristics, clinical, laboratory and sonographic findings of 160 CCHF confirmed cases during 2003 and 2012 in Zabol (A city in Sistan and Baluchestan province of Iran). The association between these factors and the fatal outcome was evaluated by regression analysis. Results: The disease had a fatal outcome in 7 (4.4%) of patients. Females had more severe symptoms and higher odds for death (odds ratio11.57, p=0.005). Leukocytosis (p<0.001), PT (p<0.001) and PTT (p=0.008) elongation, AST (p=0.010) and ALT (p<0.001) elevation were significantly associated with fatal outcome. CNS related symptoms (odds ratio 5.9, p=0.027) in clinical examination and ascites (odds ratio 38.4, p=0.012) and liquid in the pelvic cavity (odds ratio 24.2, p=0.004) were also identified as risk factors of death in this study. Conclusions: Our data suggest that in addition to clinical and laboratory findings practitioners consider sonography for CCHF prognosis.


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