scholarly journals Assessing excess mortality in times of pandemics based on principal component analysis of weekly mortality data—the case of COVID-19

Genus ◽  
2021 ◽  
Vol 77 (1) ◽  
Author(s):  
Patrizio Vanella ◽  
Ugofilippo Basellini ◽  
Berit Lange

AbstractThe COVID-19 outbreak has called for renewed attention to the need for sound statistical analyses to monitor mortality patterns and trends over time. Excess mortality has been suggested as the most appropriate indicator to measure the overall burden of the pandemic in terms of mortality. As such, excess mortality has received considerable interest since the outbreak of COVID-19 began.Previous approaches to estimate excess mortality are somewhat limited, as they do not include sufficiently long-term trends, correlations among different demographic and geographic groups, or autocorrelations in the mortality time series. This might lead to biased estimates of excess mortality, as random mortality fluctuations may be misinterpreted as excess mortality.We propose a novel approach that overcomes the named limitations and draws a more realistic picture of excess mortality. Our approach is based on an established forecasting model that is used in demography, namely, the Lee-Carter model. We illustrate our approach by using the weekly age- and sex-specific mortality data for 19 countries and the current COVID-19 pandemic as a case study. Our findings show evidence of considerable excess mortality during 2020 in Europe, which affects different countries, age, and sex groups heterogeneously. Our proposed model can be applied to future pandemics as well as to monitor excess mortality from specific causes of death.

2021 ◽  
Vol 13 (9) ◽  
pp. 239
Author(s):  
Danveer Rajpal ◽  
Akhil Ranjan Garg ◽  
Om Prakash Mahela ◽  
Hassan Haes Alhelou ◽  
Pierluigi Siano

Hindi is the official language of India and used by a large population for several public services like postal, bank, judiciary, and public surveys. Efficient management of these services needs language-based automation. The proposed model addresses the problem of handwritten Hindi character recognition using a machine learning approach. The pre-trained DCNN models namely; InceptionV3-Net, VGG19-Net, and ResNet50 were used for the extraction of salient features from the characters’ images. A novel approach of fusion is adopted in the proposed work; the DCNN-based features are fused with the handcrafted features received from Bi-orthogonal discrete wavelet transform. The feature size was reduced by the Principal Component Analysis method. The hybrid features were examined with popular classifiers namely; Multi-Layer Perceptron (MLP) and Support Vector Machine (SVM). The recognition cost was reduced by 84.37%. The model achieved significant scores of precision, recall, and F1-measure—98.78%, 98.67%, and 98.69%—with overall recognition accuracy of 98.73%.


2020 ◽  
Author(s):  
Xiaomei Wu ◽  
Bo Zhu ◽  
Shuang Xu ◽  
Yong Liu ◽  
Yifei Bi ◽  
...  

Abstract Background Tobacco exposure (TE) is the major contributor of CVD mortality, but few published studies on CVD mortality attributable to TE analyzed the possible reasons underlying the long-term trends in China. Methods The mortality data in China, Japan, USA and World were obtained from GBD 2017. The joinpoint regression was used to assess the magnitude and direction of trends over time for CVD mortality, and the age-period-cohort method was used to analyze the temporal trends of CVD mortality by age, period, and cohort. Results There was a significant downward trend in age-standardized mortality rate (ASMR) of CVD attributable to smoking in four regions, but China has the smallest decline and the ASMR in China rose to the first rank in 2017. All the net drifts per year in four regions were negative, and the local drifts were below zero. The longitudinal age curves of the CVD mortality attributable to smoking increased in four regions and China had the largest increase. The period/cohort RRs indicated a decline, and China has the smallest decline. We further analyzed the trend of IHD and stroke, and found the morality, period/cohort RR of IHD in China was always in high level. Conclusions CVD mortality attributable to TE had declined in four regions, and it was at a high level in China. The proportion of IHD mortality attributable to TE had been similar to stroke, which had significantly changed the traditional cognition of CVD composition, and the control measure was not enough for IHD in China.


Crisis ◽  
2011 ◽  
Vol 32 (4) ◽  
pp. 178-185 ◽  
Author(s):  
Maurizio Pompili ◽  
Marco Innamorati ◽  
Monica Vichi ◽  
Maria Masocco ◽  
Nicola Vanacore ◽  
...  

Background: Suicide is a major cause of premature death in Italy and occurs at different rates in the various regions. Aims: The aim of the present study was to provide a comprehensive overview of suicide in the Italian population aged 15 years and older for the years 1980–2006. Methods: Mortality data were extracted from the Italian Mortality Database. Results: Mortality rates for suicide in Italy reached a peak in 1985 and declined thereafter. The different patterns observed by age and sex indicated that the decrease in the suicide rate in Italy was initially the result of declining rates in those aged 45+ while, from 1997 on, the decrease was attributable principally to a reduction in suicide rates among the younger age groups. It was found that socioeconomic factors underlined major differences in the suicide rate across regions. Conclusions: The present study confirmed that suicide is a multifaceted phenomenon that may be determined by an array of factors. Suicide prevention should, therefore, be targeted to identifiable high-risk sociocultural groups in each country.


Author(s):  
Augusto Cerqua ◽  
Roberta Di Stefano ◽  
Marco Letta ◽  
Sara Miccoli

AbstractEstimates of the real death toll of the COVID-19 pandemic have proven to be problematic in many countries, Italy being no exception. Mortality estimates at the local level are even more uncertain as they require stringent conditions, such as granularity and accuracy of the data at hand, which are rarely met. The “official” approach adopted by public institutions to estimate the “excess mortality” during the pandemic draws on a comparison between observed all-cause mortality data for 2020 and averages of mortality figures in the past years for the same period. In this paper, we apply the recently developed machine learning control method to build a more realistic counterfactual scenario of mortality in the absence of COVID-19. We demonstrate that supervised machine learning techniques outperform the official method by substantially improving the prediction accuracy of the local mortality in “ordinary” years, especially in small- and medium-sized municipalities. We then apply the best-performing algorithms to derive estimates of local excess mortality for the period between February and September 2020. Such estimates allow us to provide insights about the demographic evolution of the first wave of the pandemic throughout the country. To help improve diagnostic and monitoring efforts, our dataset is freely available to the research community.


2021 ◽  
Vol 25 (3) ◽  
pp. 711-738
Author(s):  
Phu Pham ◽  
Phuc Do

Link prediction on heterogeneous information network (HIN) is considered as a challenge problem due to the complexity and diversity in types of nodes and links. Currently, there are remained challenges of meta-path-based link prediction in HIN. Previous works of link prediction in HIN via network embedding approach are mainly focused on exploiting features of node rather than existing relations in forms of meta-paths between nodes. In fact, predicting the existence of new links between non-linked nodes is absolutely inconvincible. Moreover, recent HIN-based embedding models also lack of thorough evaluations on the topic similarity between text-based nodes along given meta-paths. To tackle these challenges, in this paper, we proposed a novel approach of topic-driven multiple meta-path-based HIN representation learning framework, namely W-MMP2Vec. Our model leverages the quality of node representations by combining multiple meta-paths as well as calculating the topic similarity weight for each meta-path during the processes of network embedding learning in content-based HINs. To validate our approach, we apply W-TMP2Vec model in solving several link prediction tasks in both content-based and non-content-based HINs (DBLP, IMDB and BlogCatalog). The experimental outputs demonstrate the effectiveness of proposed model which outperforms recent state-of-the-art HIN representation learning models.


2021 ◽  
pp. 1-11
Author(s):  
Aysu Melis Buyuk ◽  
Gul T. Temur

In line with the increase in consciousness on sustainability in today’s global world, great emphasis has been attached to food waste management. Food waste is a complex issue to manage due to uncertainties on quality, quantity, location, and time of wastes, and it involves different decisions at many stages from seed to post-consumption. These ambiguities re-quire that some decisions should be handled in a linguistic and ambiguous environment. That forces researchers to benefit from fuzzy sets mostly utilized to deal with subjectivity that causes uncertainty. In this study, as a novel approach, the spherical fuzzy analytic hierarchy process (SFAHP) was used to select the best food treatment option. In the model, four main criteria (infrastructural, governmental, economic, and environmental) and their thirteen sub-criteria are considered. A real case is conducted to show how the proposed model can be used to assess four food waste treatment options (composting, anaerobic digestion, landfilling, and incineration). Also, a sensitivity analysis is generated to check whether the evaluations on the main criteria can change the results or not. The proposed model aims to create a subsidiary tool for decision makers in relevant companies and institutions.


Sensors ◽  
2021 ◽  
Vol 21 (10) ◽  
pp. 3527
Author(s):  
Melanija Vezočnik ◽  
Roman Kamnik ◽  
Matjaz B. Juric

Inertial sensor-based step length estimation has become increasingly important with the emergence of pedestrian-dead-reckoning-based (PDR-based) indoor positioning. So far, many refined step length estimation models have been proposed to overcome the inaccuracy in estimating distance walked. Both the kinematics associated with the human body during walking and actual step lengths are rarely used in their derivation. Our paper presents a new step length estimation model that utilizes acceleration magnitude. To the best of our knowledge, we are the first to employ principal component analysis (PCA) to characterize the experimental data for the derivation of the model. These data were collected from anatomical landmarks on the human body during walking using a highly accurate optical measurement system. We evaluated the performance of the proposed model for four typical smartphone positions for long-term human walking and obtained promising results: the proposed model outperformed all acceleration-based models selected for the comparison producing an overall mean absolute stride length estimation error of 6.44 cm. The proposed model was also least affected by walking speed and smartphone position among acceleration-based models and is unaffected by smartphone orientation. Therefore, the proposed model can be used in the PDR-based indoor positioning with an important advantage that no special care regarding orientation is needed in attaching the smartphone to a particular body segment. All the sensory data acquired by smartphones that we utilized for evaluation are publicly available and include more than 10 h of walking measurements.


Risks ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 44
Author(s):  
Selin Özen ◽  
Şule Şahin

Index-based hedging solutions are used to transfer the longevity risk to the capital markets. However, mismatches between the liability of the hedger and the hedging instrument cause longevity basis risk. Therefore, an appropriate two-population model to measure and assess longevity basis risk is required. In this paper, we aim to construct a two-population mortality model to provide an effective hedge against the basis risk. The reference population is modelled by using the Lee–Carter model with the renewal process and exponential jumps, and the dynamics of the book population are specified. The analysis based on the U.K. mortality data indicate that the proposed model for the reference population and the common age effect model for the book population provide a better fit compared to the other models considered in the paper. Different two-population models are used to investigate the impact of sampling risk on the index-based hedge, as well as to analyse the risk reduction regarding hedge effectiveness. The results show that the proposed model provides a significant risk reduction when mortality jumps and sampling risk are taken into account.


2021 ◽  
pp. e1-e6
Author(s):  
Megan Todd ◽  
Meagan Pharis ◽  
Sam P. Gulino ◽  
Jessica M. Robbins ◽  
Cheryl Bettigole

Objectives. To estimate excess all-cause mortality in Philadelphia, Pennsylvania, during the COVID-19 pandemic and understand the distribution of excess mortality in the population. Methods. With a Poisson model trained on recent historical data from the Pennsylvania vital registration system, we estimated expected weekly mortality in 2020. We compared these estimates with observed mortality to estimate excess mortality. We further examined the distribution of excess mortality by age, sex, and race/ethnicity. Results. There were an estimated 3550 excess deaths between March 22, 2020, and January 2, 2021, a 32% increase above expectations. Only 77% of excess deaths (n=2725) were attributed to COVID-19 on the death certificate. Excess mortality was disproportionately high among older adults and people of color. Sex differences varied by race/ethnicity. Conclusions. Excess deaths during the pandemic were not fully explained by COVID-19 mortality; official counts significantly undercount the true death toll. Far from being a great equalizer, the COVID-19 pandemic has exacerbated preexisting disparities in mortality by race/ethnicity. Public Health Implications. Mortality data must be disaggregated by age, sex, and race/ethnicity to accurately understand disparities among groups. (Am J Public Health. Published online ahead of print June 10, 2021: e1–e6. https://doi.org/10.2105/AJPH.2021.306285 )


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