Genetic anticipation and imprinting in bipolar I illness

1997 ◽  
Vol 170 (2) ◽  
pp. 162-166 ◽  
Author(s):  
Maria Grigoroiu-Serbanescu ◽  
Pryia J. Wickramaratne ◽  
Susan E. Hodge ◽  
Stefan Milea ◽  
Radu Mihailescu
Keyword(s):  
Age At Onset ◽  
Diagnostic Interview ◽  
Young Age ◽  
Genetic Studies ◽  
Affection Status ◽  
Genetic Anticipation ◽  
The Family ◽  
Family Interview ◽  
The Relationship ◽  
Anticipation Effects

BackgroundThe study focused on: (1) the existence of genetic anticipation in a randomly selected sample of bipolar I patients using broad and narrow definitions of the affection status in the parental generation; (2) the relationship between anticipation and the age at investigation in probands and in their relatives; (3) the relationship between anticipation and imprinting.MethodOne hundred and fifteen bipolar I patients and their first- to third-degree relatives were diagnosed according to DSM–III–R criteria using the Diagnostic Interview for Genetic Studies and the Family Interview for Genetic Studies.ResultsAge at onset was found to be 6–10 years younger in probands with affected parents or uncles/aunts. Two-thirds of these families showed positive anticipation under both the broad and the narrow definitions of affection status in the parents' generation. The age at investigation was younger in probands showing positive anticipation. Anticipation was found only in probands inheriting the disorder from the paternal side.ConclusionsIn spite of the inevitable association between young current age and young age at onset, which could result in spurious anticipation effects, our findings suggest that this phenomenon is not the sole cause of observed anticipation.

scholarly journals Hubungan Pengetahuan dan Stigma pada Keluarga dengan Beban Keluarga Dalam Merawat Pasien Skizofrenia di Wilayah Kerja Puskesmas Nanggalo Padang

2021 ◽  
Vol 16 (2) ◽  
pp. 57-68
Author(s):  
Ziqni Ilma Al Wasi ◽  
Dewi Eka Putri ◽  
Renidayati Renidayati
Keyword(s):  
Health Workers ◽  
Research Result ◽  
Family Burden ◽  
Heavy Load ◽  
Cross Sectional ◽  
The Family ◽  
Heavy Burden ◽  
Family Interview ◽  
Level Of Knowledge ◽  
The Relationship

Families have a heavy burden in caring for ODS. Heavy load perceived by the family due to the level of family knowledge and family stigma. This study aims to determine the relationship knowledge and stigma on families with family burdens in caring schizophrenia patient in the working area of ​​Puskesmas Nanggalo Padang. Types of research this is correlation with the approach cross sectional. The population in this study is a family who cares for ODS in the working area of ​​Puskemas Nanggalo Padang and a sample of 87 people taken withPurposive Sampling. Data collection using a questionnaire Family Interview Scale / Stigma Items, questionnaire knowledge, and a questionnaire Zarit Burden Interview (ZBI). Research result It was found that more than half (59.8%) of the families experienced a heavy burden, more than half (57.5%) of families have a lower or higher level of knowledge half (52.9%) of families experienced high stigma. There is a relationship meaning between the stigma in the family and the family burden (p =0,000). There is no significant relationship between the level of family knowledge with family burden (p =0.110). It is expected that health workers, especially nurses soul in society to provide health education to the community regarding Schizophrenia. So that society no longer gives stigma to families who will make the family embarrassed in caring for ODS.

Intergenerational Family Relations in Luxembourg

2013 ◽  
Vol 18 (1) ◽  
pp. 59-69 ◽  
Author(s):  
Isabelle Albert ◽  
Dieter Ferring ◽  
Tom Michels
Keyword(s):  
Family Relations ◽  
Family Values ◽  
Generation Gap ◽  
Intergenerational Solidarity ◽  
Acculturation Gap ◽  
Family Obligations ◽  
Mothers And Daughters ◽  
The Family ◽  
The Relationship ◽  
Model Family

According to the intergenerational solidarity model, family members who share similar values about family obligations should have a closer relationship and support each other more than families with a lower value consensus. The present study first describes similarities and differences between two family generations (mothers and daughters) with respect to their adherence to family values and, second, examines patterns of relations between intergenerational consensus on family values, affectual solidarity, and functional solidarity in a sample of 51 mother-daughter dyads comprising N = 102 participants from Luxembourgish and Portuguese immigrant families living in the Grand Duchy of Luxembourg. Results showed a small generation gap in values of hierarchical gender roles, but an acculturation gap was found in Portuguese mother-daughter dyads regarding obligations toward the family. A higher mother-daughter value consensus was related to higher affectual solidarity of daughters toward their mothers but not vice versa. Whereas affection and value consensus both predicted support provided by daughters to their mothers, affection mediated the relationship between consensual solidarity and received maternal support. With regard to mothers, only affection predicted provided support for daughters, whereas mothers’ perception of received support from their daughters was predicted by value consensus and, in the case of Luxembourgish mothers, by affection toward daughters.

The Use of Medical Record Linkage for Population and Genetic Studies

1969 ◽  
Vol 08 (01) ◽  
pp. 07-11 ◽  
Author(s):  
H. B. Newcombe
Keyword(s):  
Record Linkage ◽  
Large Scale ◽  
Medical Record Linkage ◽  
Canadian Province ◽  
Genetic Studies ◽  
Parental Characteristics ◽  
Family Histories ◽  
The Family ◽  
Large Populations ◽  
Machine Readable

Methods are described for deriving personal and family histories of birth, marriage, procreation, ill health and death, for large populations, from existing civil registrations of vital events and the routine records of ill health. Computers have been used to group together and »link« the separately derived records pertaining to successive events in the lives of the same individuals and families, rapidly and on a large scale. Most of the records employed are already available as machine readable punchcards and magnetic tapes, for statistical and administrative purposes, and only minor modifications have been made to the manner in which these are produced.As applied to the population of the Canadian province of British Columbia (currently about 2 million people) these methods have already yielded substantial information on the risks of disease: a) in the population, b) in relation to various parental characteristics, and c) as correlated with previous occurrences in the family histories.

Family Firms, Social Responsibility, and Non-Family Member Employees Identification

Think India ◽  
2013 ◽  
Vol 16 (3) ◽  
pp. 10-19
Author(s):  
Ang Bao
Keyword(s):  
Resource Allocation ◽  
Social Responsibility ◽  
Family Member ◽  
Program Implementation ◽  
Social Identity Theory ◽  
Family Firms ◽  
The Family ◽  
Corporate Social ◽  
The Relationship ◽  
Csr Engagement

The objective of this paper is to find the relationship between family firms’ CSR engagement and their non-family member employees’ organisational identification. Drawing upon the existing literature on social identity theory, corporate social responsibility and family firms, the author proposes that family firms engage actively in CSR programs in a balanced manner to increase non-family member employees’ organisational identification. The findings of the research suggest that by developing and implementing balanced CSR programs, and actively getting engaged in CSR activities, family firms may help their non-family member employees better identify themselves with the firms. The article points out that due to unbalanced CSR resource allocation, family firms face the problem of inefficient CSR program implementation, and are suggested to switch alternatively to an improved scheme. Family firms may be advised to take corresponding steps to select right employees, communicate better with non-family member employees, use resources better and handle firms’ succession problems efficiently. The paper extends employees’ identification and CSR research into the family firm research domain and points out some drawbacks in family firms’ CSR resource allocation while formerly were seldom noticed.

Organization of Individual Counselling of Children Brought up in Foster Families (on the example of the «Family» Centre»)

2020 ◽  
pp. 42-50
Author(s):  
Aygul Fazlyeva ◽  
Aliya Akhmetshina
Keyword(s):  
Interpersonal Relationships ◽  
Personal Characteristics ◽  
Social Situation ◽  
Individual Counseling ◽  
Emotional Instability ◽  
Foster Families ◽  
Individual Counselling ◽  
The Social ◽  
The Family ◽  
The Relationship

Children, brought up in foster families, experience various problems (diffi culties in interpersonal relationships with parents, diffi culties in communicating with peers, emotional instability), which lead to confl icts, quarrels, running away from home, destructive phenomena, etc. One of the eff ective forms of working with children brought up in foster families is individual counselling. Individual counselling is used by various specialists (psychologists, educators, psychotherapists), where a special place is taken by a social educator. His or her activity involves the implementation of social-protective, preventive, educational, informational, advisory functions. In the process of organizing individual counseling, the social educator takes into account the social situation of the family and the child, personal characteristics, social conditions, social and cultural characteristics and the nature of the relationship with the social environment. To organize individual counseling, a social educator needs to master various and eff ective techniques, and take into account a number of recommendations. An analysis of the literature and practical socio-pedagogical experience led to an understanding of the insuffi cient degree of elaboration of this issue. The purpose of this article was the solution to this problem.

CHILD-PARENT RELATIONS AS A FACTOR IN THE FORMATION OF PROFESSIONAL PREFERENCES IN PEDAGOGICAL DYNASTIES

2020 ◽  
Vol 2 (4) ◽  
pp. 126-130
Author(s):  
N. V. SHAMANIN ◽  
Keyword(s):  
Professional Development ◽  
The Family ◽  
The Individual ◽  
Relationship Of ◽  
The Relationship ◽  
Parent Child Relationships ◽  
Professional Preferences ◽  
Parent Child

The article raises the issue of the relationship of parent-child relationships and professional preferences in pedagogical dynasties. Particular attention is paid to the role of the family in the professional development of the individual. It has been suggested that there is a relationship between parent-child relationships and professional preferences.

War Widows and Welfare Queens

2019 ◽  
pp. 584-605
Author(s):  
Brittany Pearl Battle
Keyword(s):  
Policy Development ◽  
Social Welfare Policy ◽  
Cultural Representations ◽  
The Poor ◽  
The Social ◽  
The Family ◽  
Deserving Poor ◽  
Analytical Tools ◽  
The Relationship ◽  
Undeserving Poor

This chapter examines the sociocognitive dimensions of cultural categorizations of deservingness. The social issue of poverty has been a persistent source of debate in the American system of policy development, influenced by conceptual distinctions between the “haves” and “have-nots,” “working moms” and “unemployed dads,” and the “deserving poor” and the “undeserving poor.” Although there is a wealth of literature discussing the ideological underpinnings of stratification systems, these discussions often focus on categorical distinctions between the poor and the nonpoor, with much less discussion of distinctions made among the poor. Moreover, while scholars of culture and policy have long referenced the importance of cultural categories of worthiness in policy development, the theoretical significance of these distinctions has been largely understudied. I expand the discourse on the relationship between cultural representations of worth and social welfare policy by exploring how these categories are conceptualized. Drawing on analytical tools from a sociology of perception framework, I create a model that examines deservingness along continuums of morality and eligibility to highlight the taken-for-granted cultural subtleties that shape perceptions of the poor. I focus on social filters created by norms of poverty, welfare, and the family to explore how the deserving are differentiated from the undeserving.

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