scholarly journals Assessing outcomes for cost-utility analysis in depression: comparison of five multi-attribute utility instruments with two depression-specific outcome measures

2014 ◽  
Vol 205 (5) ◽  
pp. 390-397 ◽  
Author(s):  
Cathrine Mihalopoulos ◽  
Gang Chen ◽  
Angelo Iezzi ◽  
Munir A. Khan ◽  
Jeffrey Richardson
Keyword(s):  
Mental Health ◽  
Outcome Measures ◽  
Goodness Of Fit ◽  
Short Form ◽  
Cost Utility ◽  
Self Report ◽  
Life Years ◽  
Psychological Distress Scale ◽  
Distress Scale ◽  
Disease Specific

BackgroundMany mental health surveys and clinical studies do not include a multi-attribute utility instrument (MAUI) that produces quality-adjusted life-years (QALYs). There is also some question about the sensitivity of the existing utility instruments to mental health.AimsTo compare the sensitivity of five commonly used MAUIs (Assessment of Quality of Life – Eight Dimension Scale (AQoL-8D), EuroQoL–five dimension (EQ-5D-5L), Short Form 6D (SF-6D), Health Utilities Index Mark 3 (HUI3), 15D) with that of disease-specific depression outcome measures (Depression Anxiety Stress Scales (DASS-21) and the Kessler Psychological Distress Scale (K10)) and develop ‘crosswalk’ transformation algorithms between the measures.MethodIndividual data from 917 people with self-report depression collected as part of the International Multi-Instrument Comparison Survey.ResultsAll the MAUIs discriminated between the levels of severity measured by the K10 and the DASS-21. The AQoL-8D had the highest correlation with the disease-specific measures and the best goodness-of-fit transformation properties.ConclusionsThe algorithms developed in this study can be used to determine cost-effectiveness of services or interventions where utility measures are not collected.

scholarly journals Effects associated with the use of healthcare for eating disorders by women in the community: a longitudinal cohort study

BMJ Open ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. e033986
Author(s):  
Nicol Holtzhausen ◽  
Haider Mannan ◽  
Nasim Foroughi ◽  
Phillipa Hay
Keyword(s):  
Mental Health ◽  
Eating Disorder ◽  
Psychological Distress ◽  
Symptom Severity ◽  
Tertiary Education ◽  
Short Form ◽  
Self Report ◽  
Longitudinal Cohort ◽  
Distress Scale ◽  
Over Time

ObjectivesThis study examined formal and informal healthcare use (HCU) in community women with disordered eating, and associations of HCU with mental health-related quality of life (MHRQoL), psychological distress, mental health literacy (MHL) and eating disorder (ED) symptoms over time.HypothesisWe hypothesised that HCU would lead to improvement in ED symptom severity, MHRQoL, MHL and psychological distress.Design, setting, participantsData were from years 2, 4 and 9 of a longitudinal cohort of 443 community women (mean age 30.6, SE 0.4 years) with a range of ED symptoms, randomly recruited from the Australian Capital Territory electoral role or via convenience sampling from tertiary education centres. Data were collected using posted/emailed self-report questionnaires; inclusion criteria were completion of the HCU questionnaire at time point of 2 years (baseline for this study). HCU was measured using a multiple-choice question on help seeking for an eating problem. To test the effect of HCU over time on MHRQoL (Short Form-12 score), psychological distress (Kessler Psychological Distress Scale score), ED symptom severity (Eating Disorder Examination Questionnaire score) and ED–MHL, linear or logistic mixed-effects regression analyses were used.Results20% of participants sought ED-specific help at baseline; more than half of participants sought help that was not evidence based. HCU at baseline was significantly associated with improved MHRQoL and ED symptom severity and decreased psychological distress over time (Cohen’s d all >0.3, ie, small). HCU was not significantly associated with MHL over time. The predictive ability of the fitted models ranged from 32.18% to 42.42% for psychological distress and MHL treatment, respectively.ConclusionsFormal and informal HCU were associated with small improvements in ED symptoms, MHRQoL and psychological distress but not with improved MHL. Informal services in ED management should be investigated further along with efforts to improve ED–MHL.

Social network factors as mediators of mental health and psychological distress

2017 ◽  
Vol 63 (3) ◽  
pp. 235-243 ◽  
Author(s):  
Andrew Levula ◽  
Michael Harré ◽  
Andrew Wilson
Keyword(s):  
Mental Health ◽  
Psychological Distress ◽  
Social Network ◽  
Social Isolation ◽  
Indirect Effect ◽  
Social Connectedness ◽  
Short Form ◽  
Sf 36 ◽  
Psychological Distress Scale ◽  
Distress Scale

Background: Although mental health (MH) is overall strongly associated with psychological distress (PD), this association is very weak for the sample with high PD. This relationship remains understudied. Aim: This study examines the association between MH and PD and whether this association is mediated by social network (SN) factors for individuals with high PD. Method: Data were taken from the Household Income and Labour Dynamics in Australia study ( N = 756). MH was measured using the MH sub-scale of the general health survey (Short Form (SF)-36) and PD was measured using the Kessler Psychological Distress Scale (K10). The SN measures were derived from the self-completion questionnaire. Using bootstrap mediation analysis, we tested whether the association between MH and PD is mediated by SN factors. Result: The correlation between MH and PD was r = −.410 ( p < .001). The mediational analysis results show that social isolation mediates the association between MH and PD with an indirect effect of β = −0.0070 (confidence interval (CI) = −0.0133 to −0.0023). Moreover, social connections also mediated the association between MH and PD with an indirect effect of β = −0.0073 (CI = −0.0141 to −0.0028). Conclusion: This study has practical implications for the design of social policies that attempt to reduce social isolation and enhance social connectedness to protect MH.

scholarly journals Utility Estimation of Health Status of Cancer Patients by Mapping for Cost-Utility Analysis

2019 ◽  
Author(s):  
Ali Reza Mortezaei ◽  
Marziyeh Rajabi ◽  
Masoumeh Erfani Khanghahi ◽  
Hossein Ameri
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Goodness Of Fit ◽  
Short Form ◽  
Predictive Performance ◽  
Ordinary Least Squares ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis ◽  
Life Years

Background: It is important to obtain accurate information about the preferences of people for measuring quality-adjusted life years (QALYs), because it is necessary for cost-utility analysis. In this regard, mapping is a method to access this information. Therefore, the purpose of this study was to map Functional Assessment of Cancer Therapy – General (FACT-G) onto Short Form Six Dimension (SF-6D) in breast cancer patients to provide appropriate conditions for a detailed cost-utility analysis. Methods: This descriptive analytical study was conducted on 416 patients with breast cancer. The SF-6D and FACT-G questionnaires were completed for patients selected by consecutive sampling from the Imam Khomeini Cancer Institute in Tehran in 2018. The Ordinary Least Squares model was used to estimate the value of utility and the models' goodness of fit was evaluated using R2. In addition, models' predictive performance was assessed by Mean Absolute Error (MAE), Root Mean Square Error (RMSE), and Minimal Important Difference (MID) conducted between the observed and predicted SF-6D values. Models were validated using a 10-fold cross validation method. Results: Given the criteria of goodness of fit, model 2 was the best (R2 = 41.19 %). Moreover, findings of the predictive performance of models showed that model 2 was the best (MAE = 0.06943, RMSE = 0.09031, and MID = 0.0003). Conclusions: Findings showed that the developed algorithm had a good predictive ability. So, it can enable the policymakers and researchers to convert cancer-specific health-related quality of life instruments to preference-based instruments.

scholarly journals Exploring the Relationships of Physical Activity, Emotional Intelligence, and Mental Health Among College Students

2020 ◽  
Vol 29 (2) ◽  
Author(s):  
Amir Bhochhibhoya ◽  
Paul Branscum ◽  
E. Laurette Taylor ◽  
Craig Hofford
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Emotional Intelligence ◽  
Undergraduate Students ◽  
Self Report ◽  
Standardized Assessments ◽  
Psychological Distress Scale ◽  
Distress Scale ◽  
The Relationship ◽  
Kessler Psychological Distress Scale

The purpose of this study was to explore the relationship among physical activity (PA), emotionalintelligence (EI), and mental health in a sample of university undergraduate students (n=438). All participants were asked to complete three standardized assessments: the International Physical Activity Questionnaire, the Schutte Self-Report Emotional Intelligence Test, and the Kessler Psychological Distress Scale. Results showed that participants who reported higher levels of PA scored significantly higher in Global EI (p = 0.031) and mental health (p = 0.049) compared to participants with moderate and low levels of PA. Results also indicated that whereas Global EI was a significant predictor of PA, it was mediated by the relationship between mental health and PA.

The mental health of Australian medical practitioners during Covid-19

2021 ◽  
pp. 103985622110108
Author(s):  
Michelle Anne Adams ◽  
Matthew Brazel ◽  
Richard Thomson ◽  
Hannah Lake
Keyword(s):  
Mental Health ◽  
Junior Doctor ◽  
Demographic Factors ◽  
Cross Sectional Survey ◽  
Mental Health Diagnosis ◽  
Cross Sectional ◽  
Medical Practitioners ◽  
Psychological Distress Scale ◽  
Distress Scale ◽  
Health Diagnosis

Objectives: To ascertain whether doctors were experiencing higher rates of distress during Covid-19 and whether this was impacted by demographic factors. Our hypotheses were that being a junior doctor, having a previous mental health diagnosis and treating Covid-19 positive patients would predict higher rates of distress. Methods: Cross-sectional survey conducted via Survey Monkey. Voluntary participants were recruited from the mailing list of a national-based referral service for doctors to psychiatrists. Distress was measured using the Kessler Psychological Distress Scale (K10). Demographic factors were analysed for predictive value of a higher rating on the K10. Areas of concern in relation to Covid-19 and preference for support services were measured on a Likert scale and compared to levels of distress. Results: The rate of very high distress was 15%. Being a junior doctor and having a previous mental health diagnosis were predictive factors of a higher K10 score. K10 was not affected by likelihood of contact with Covid-19-positive patients. Social isolation had a larger impact on mental health in the context of a previous psychiatric diagnosis. Face-to-face assessments were preferred. Conclusions: Rates of distress in doctors have been higher than baseline during Covid-19. Some groups have been particularly vulnerable.

scholarly journals Suicidal Ideation and Predictors of Psychological Distress during the COVID-19 Pandemic in Eswatini: A Population-Based Household Telephone Survey

2021 ◽  
Vol 18 (13) ◽  
pp. 6700
Author(s):  
Mduduzi Colani Shongwe ◽  
Song-Lih Huang
Keyword(s):  
Mental Health ◽  
Psychological Distress ◽  
Suicidal Ideation ◽  
Telephone Survey ◽  
Population Based ◽  
Cross Sectional ◽  
Increased Risk ◽  
Psychological Distress Scale ◽  
The Government ◽  
Distress Scale

The unpredictability of the COVID-19 pandemic can induce psychological distress in individuals. We investigated perceived stressors, prevalence of psychological distress and suicidal ideation, and predictors of psychological distress among adults during the COVID-19 pandemic in Eswatini. This study was a cross-sectional, population-based household telephone survey of 993 conveniently sampled adults (18+ years) from all the four administrative regions of Eswatini. Data were collected between 9 June and 18 July 2020 during the first wave of the COVID-19 pandemic, when the country was under a partial lockdown. COVID-19-related psychological distress was assessed using the Kessler 6-item Psychological Distress Scale (K6). We performed weighted modified Poisson regression analyses to identify significant predictors of moderate/severe psychological distress (K6 scores: ≥5). The weighted prevalences of moderate (K6 scores: 5–12) and severe psychological distress (K6 scores: ≥13) were 41.7% and 5.4%, respectively. Participants reported several perceived COVID-19-related stressors, including worries and fears of the contagion-specific death, serious need for food and money, and concerns about loss of income or business. The weighted prevalence of suicidal ideation was 1.5%. Statistically significant predictors of increased risk for moderate/severe psychological distress included living in the Hhohho and Manzini regions; feeling not well informed about COVID-19; feeling lonely; having received COVID-19 food or financial relief from the government; feeling burdened by the lockdown; being married; and being youth (18–24 years). The results call for the government to urgently augment the provision of mental health services during the pandemic. Mental health practitioners and programs may use several stressors and risk factors identified in this study to inform interventions and government policies aimed at reducing psychological distress induced by the pandemic.

Mental health economics: current methodological issues

2011 ◽  
Vol 20 (3) ◽  
pp. 239-243 ◽  
Author(s):  
P. McCrone
Keyword(s):  
Mental Health ◽  
Health Care ◽  
Mental Health Care ◽  
Health Care Services ◽  
Self Report ◽  
Economic Evaluations ◽  
Methodological Issues ◽  
Care Services ◽  
Life Years ◽  
Mental Health Economics

Background:Investment in innovative mental health care services requires the use of scarce resources that could be used in alternative ways. Economic evaluation is essential to ensure that such an investment is appropriately compared with investment elsewhere.Method:A non-systematic review of mental health evaluations identifies key methodological issues pertaining to economic studies.Results:Economic evaluations require the measurement and combination of costs and outcomes, and clarity about how this measurement is undertaken is required. Regarding costs, important considerations relate to the perspective to be taken (e.g., health service or societal), method of measurement (patient self-report or use of databases) and valuation (actual costs, fees or expenditure). Decision makers frequently need to compare evidence both within and between clinical areas and therefore there is a tension between the use of condition specific and generic outcome measures. Quality-adjusted life years are frequently used in economic evaluations, but their appropriateness in mental health care studies is still debated.Conclusions:Economic evaluations in the area of mental health care are increasing in number and it is essential that researchers continue to develop and improve methods used to conduct such studies.

The Use of Disease-Specific Outcome Measures in Cost-Utility Analysis

2007 ◽  
Vol 25 (7) ◽  
pp. 591-603 ◽  
Author(s):  
Leida M Lamers ◽  
Carin A Uyl-de Groot ◽  
Ivonne Buijt
Keyword(s):  
Outcome Measures ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis ◽  
Specific Outcome ◽  
Disease Specific

scholarly journals OMERACT Quality-adjusted Life-years (QALY) Working Group: Do Current QALY Measures Capture What Matters to Patients?

2017 ◽  
Vol 44 (12) ◽  
pp. 1899-1903 ◽  
Author(s):  
Logan Trenaman ◽  
Annelies Boonen ◽  
Francis Guillemin ◽  
Mickael Hiligsmann ◽  
Alison Hoens ◽  
...  
Keyword(s):  
Health Outcomes ◽  
Outcome Measures ◽  
Scoping Review ◽  
Short Form ◽  
Future Research ◽  
Quality Adjusted Life Years ◽  
Life Years ◽  
Patient Reported ◽  
Quality Adjusted Life ◽  
What Matters

Objective.To understand the limitations with current patient-reported outcome measures (PROM) used to generate quality-adjusted life-years (QALY) in rheumatology, and set a research agenda.Methods.Two activities were undertaken. The first was a scoping review of published studies that have used PROM to generate QALY in rheumatology between 2011 and 2016. The second was an interactive “eyeball test” exercise at Outcome Measures in Rheumatology 13 that compared subdomains of widely used generic PROM, as identified through the scoping review, to subdomains of the Assessment of SpondyloArthritis Health Index (ASAS-HI) condition-specific PROM for ankylosing spondylitis.Results.The scoping review included 39 studies. Five different PROM have been used to generate QALY in rheumatology; however, the EQ-5D and Short Form 6 Dimensions (SF-6D) were used most frequently (in 32 and 9 of included studies, respectively). Special interest group participants identified energy/drive and sleep as 2 key subdomains of the ASAS-HI instrument that may be missed by the EQ-5D, and sexual function as potentially missed by the SF-6D. Participants also expressed concerns that aspects of the process of care and non-health outcomes may be missed. Three ways of incorporating additional subdomains were discussed, including using an alternative generic PROM, modifying an existing generic PROM with “bolt-on” subdomain(s), and generating societal weights for a condition-specific PROM.Conclusion.Three priorities for future research were identified: understanding whether the EQ-5D and SF-6D identify what matters to patients with different rheumatic conditions, analyzing how much patients value process or non-health outcomes, and identifying which approaches to incorporating a greater number of subdomains into the QALY are being undertaken in other disease areas.

scholarly journals Do Mental Health and Vitality Mediate the Relationship between Perceived Control over Time and Fear of COVID-19? A Survey in an Italian Sample

2021 ◽  
Vol 10 (16) ◽  
pp. 3516
Author(s):  
Silvana Miceli ◽  
Barbara Caci ◽  
Michele Roccella ◽  
Luigi Vetri ◽  
Giuseppe Quatrosi ◽  
...  
Keyword(s):  
Mental Health ◽  
Perceived Control ◽  
Online Survey ◽  
Short Form ◽  
Well Being ◽  
Self Report ◽  
Treatment Programs ◽  
Effective Control ◽  
Post Traumatic Stress ◽  
Over Time

Several studies evidenced increased elevated symptomatology levels in anxiety, general stress, depression, and post-traumatic stress related to COVID-19. Real difficulties in the effective control of time that could be responsible for mental health issues and loss of vitality were also reported. Prior literature highlighted how perceived control over time significantly modulates anxiety disorders and promotes psychological well-being. To verify the hypothesis that perceived control over time predicts fear of COVID-19 and mental health and vitality mediate this relationship, we performed an online survey on a sample of 301 subjects (female = 68%; Mage = 22.12, SD = 6.29; age range = 18–57 years), testing a parallel mediation model using PROCESS macro (model 4). All participants responded to self-report measures of perceived control over time, COVID-19 fear, mental health, and vitality subscales of the Short-Form-36 Health Survey. Results corroborate the hypotheses of direct relationships between all the study variables and partially validate the mediation’s indirect effect. Indeed, mental health (a1b1 = −0.06; CI: LL = −0.11; UL = −0.01; p < 0.001) rather than vitality (a2b2 = −0.06; CI: LL = −0.09; UL = 0.03; n.s.) emerges as a significant mediator between perceived control over time and fear of COVID-19. Practical implications of the study about treatment programs based on perceived control over time and emotional coping to prevent fear and anxiety toward the COVID-19 pandemic are discussed.

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