scholarly journals Comparison of the Accuracy of Papanicolaou Test Cytology, Visual Inspection With Acetic Acid, and Visual Inspection With Lugol Iodine in Screening for Cervical Neoplasia in Southeast Nigeria

2018 ◽  
pp. 1-9 ◽  
Author(s):  
John Egede ◽  
Leonard Ajah ◽  
Perpetus Ibekwe ◽  
Uzoma Agwu ◽  
Emmanuel Nwizu ◽  
...  

Purpose This study aimed to compare the accuracy of Papanicolaou test cytology, visual inspection with 5% acetic acid (VIA), and visual inspection with Lugol iodine (VILI) in the detection of premalignant and malignant lesions of the cervix. Materials and Methods This was a cross-sectional comparative study of 200 consenting participants at the Federal Teaching Hospital, Abakaliki over a 6-month period. All the participants had Papanicolaou test cytology. Subsequently, they were classified into two groups of 100 each through systematic random sampling: group 1 had VIA and group 2 had VILI. Thereafter, all the participants had cervical punch biopsy at the 6 and 12 o’clock cervical positions. Cervical punch biopsy was also done on the suspicious lesions of the cervix irrespective of their positions. The tests of validity of the three methods were calculated using the histology of the biopsy specimen as the gold standard. P value ≤ .05 was considered to be statistically significant. Results Among the VIA group, 19 (19%) had cervical epithelial abnormalities on Papanicolaou test cytology, and VIA was positive in 14 (14%). Histology results showed cervical neoplasia in 15 (15%) of the participants. Among the VILI group, 15 (15%) had cervical epithelial abnormalities on Papanicolaou test cytology, and VILI was positive in 19 (19%). Histology results showed cervical neoplasia in 15 (15%) of the participants. There was no significant difference in overall accuracy of Papanicolaou test cytology, VIA, and VILI. The overall accuracy of the Papanicolaou test cytology plus VIA was significantly more than Papanicolaou test cytology alone. Conclusion VIA or VILI can be used as a stand-alone cervical cancer screening test when compared with Papanicolaou test cytology, particularly in resource-limited settings. VIA can also complement Papanicolaou test cytology.

2019 ◽  
Vol 6 (2) ◽  
pp. 129-141
Author(s):  
Sri Wahyuni ◽  
Ratna Puspita Adiyasa

Latar Belakang: Indonesia merupakan salah satu negara berkembang di Asia Tenggara yang  menghadapi tantangan bahaya kejadian kanker serviks. kanker serviks memiliki prevalensi tertinggi, yaitu sebesar 0,8%. Salah satu cara deteksi dini kanker seviks adalah dengan pemeriksaan Visual Inspeksi Asam Asetat (VIA). Suami merupakan orang terdekat bagi seorang isteri. Dukungan suami memiliki pengaruh yang signifikan dalam pengambilan keputusan istri, terutama yang berkaitan dengan pencegahan penyakit maupun upaya peningkatan derajat kesehatan. Tujuan: Mengetahui hubungan dukungan suami dengan partisipasi mengikuti pemeriksaan VIA pada wanita usia subur di RW 04 Kelurahan Terban Gondokusuman Yogyakarta. Metode: Desain penelitian menggunakan Analitik Deskriptif Correlation dengan pendekatan cross sectional dengan populasi semua wanita usia subur di RW 04 Kelurahan Terban Gondokusuman Yogyakarta berjumlah 72 orang. Teknik pengambilan sampel menggunakan terknik sampel proporsi sejumlah 61 orang. Pengumpulan data menggunakan kuesioner dan analisis hubungan dengan uji Chi Square dilanjutkan Coefisien Contigensi. Hasil: Analisa bivariate menunjukkan nilai p-value: 0,000 < α: 0,004, dengan keeratan 0,393 (rendah). Kesimpulan: Ada hubungan antara dukungan suami dengan partisipasi mengikuti pemeriksaan IVA di RW 04 Kelurahan Terban Gondokusuman Yogyakarta. Saran: Diharapkan bagi pemerintah untuk melibatkan suami saat melakukan pendidikan kesehatan tentang pemeriksaan IVA. Kata Kunci: Dukungan suami – Pemeriksaan IVA – Kanker Seviks   ABSTRACT Background: Indonesia is facing the challenges of the danger of cervical cancer. This disease has the highest prevalence which equals to 0,8%. Cervical cancer can be early detected by IVA test. Husband’s support has a significant influence in childbearing age woman’s decision, especially with regard to disease prevention and efforts to improve health status. Objective: To know the relationship between husband’s support with Visual Inspection with Acetic Acid (VIA) test participation of childbearing age woman in RW 04 Kelurahan Terban Gondokusuman Yogyakarta. Method: The study design was Descriptive Correlation Analysis with cross sectional approach. The population was 72 people, and the sample was 61 respondents. Data collecting used questionnaires and Chi Square tes for analysis. Results: Bivariate analysis shows p-value: 0.000 <α: 0.004, with the closeness degree of 0,393 (low correlation). Conclusion: There is a relationship between husband’s support with Visual Inspection with Acetic Acid (VIA) test participation of childbearing age woman in RW 04 Kelurahan Terban Gondokusuman Yogyakarta. Suggestion: It is expected that the government will involve husbands when conducting health education regarding VIA test. Key words : husbands support – VIA test – cervical cancer


2011 ◽  
Vol 18 (01) ◽  
pp. 89-92
Author(s):  
NAVEED SHARIF ◽  
NAZIR AHMED ◽  
FAWAD HAMEED ◽  
Nosheen Rehan ◽  
Jawad Khan

Objective: To study the age related radiological finding in pulmonary tuberculosis. Study design: A cross sectional study. Place and duration of study: From January 2009 to December 2009 pulmonary department of Bahawal Victoria Hospital Bahawal Pur. Patients and method: The cases diagnosed as pulmonary tuberculosis of either gender above age of 12 years were included in the study. Patients suffering from extra pulmonary tuberculosis, treatment failure, relapse, drug resistant tuberculosis and HIV sero-positive patients were excluded from the study. Patients were divided into groups according to the age. Group 1 consist of patients having age ≥ 50years while group 2 consist of patients having <50 years. Data was recorded on the Proforma and was analyzed statistically on SPSS 11. Results: this study consists of 106 patients and divided into two groups. It has been found that apical zone of lung involvement was more common in patients younger than 50 years while involvement of lower zone was more common in patients with age ≥50years. No significant difference was found regarding the involvement of middle zone, multiple zones and the type of lesions as the p-value was >0.05. Conclusions: the elderly patients with pulmonary tuberculosis have predominant involvement of lower zones. So, lower zone involvement of radiological lesions should be evaluated for pulmonary tuberculosis to start the treatment earlier and to minimize the risk of missing the diagnosis.


Author(s):  
Reffi Jordania Pebrina ◽  
Margaretha Kusmiyanti ◽  
Fulgensius Surianto

Abstrak Kanker serviks merupakan peringkat enam penyebab utama kematian wanita dan peringkat dua kematian pada wanita berusia 15-44 tahun. Di Asia deteksi dini penyakit kanker serviks dilakukan melalui pemeriksaan Inspeksi Visual Asam Asetat (IVA). Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berhubungan dengan pemeriksaan inspeksi visual asam asetat (IVA) di Puskesmas Cibinong Tahun 2019. Rancangan penelitian menggunakan desain cross-sectional pada 44 responden pasien KIA di Puskesmas Cibinong. Pengumpulan data di lakukan pada bulan April 2019 dengan menggunakan kuesioner dengan variabel umur, pendidikan, pekerjaan, pengetahuan, dukungan keluarga dan dukungan petugas kesehatan yang telah di uji validitas dan reliabilitas. Analisis data menggunakan uji chi square dan kendall’s tau b. Hasil menunjukkan bahwa umur (p-value 0,008) dan dukungan petugas kesehatan (p-value 0,015) berhubungan bermakna dengan pemeriksaan IVA dan faktor yang tidak berhubungan dengan pemeriksaan IVA ialah pendidikan, pekerjaan, pengetahuan dan dukungan keluarga. Hal tersebut menunjukkan perlunya peningkatan program promosi kesehatan, sosialisasi dan konseling kepada para ibu yang berkunjung ke Puskesmas Cibinong. Kata kunci: wanita, kanker serviks, Inspeksi Visual Asam Asetat (IVA) Abstract Cases of cervical cancer, as ranked 6th leading cause of female death and rank 2nd death in women aged 15-44 years. In Asia cervical cancer early screening or detection programs is through Visual Inspection with Acetic Acid (VIA). The study aims to analyze factors related to the examination of Visual Inspection with Acetic Acid (VIA) in Cibinong Health Center’s in 2019. This is a cross-sectional study with a sample of 44 respondents patient KIA in Cibinong Health Center’s. Data collection was taken through filling a set of questionnaires in April 2019 which have been tested for validity and reliability. Analysis performed by chi-square and Kendall’s tau b. The analysis shows age (p-value 0,008) and health practitioner’s support (p-value 0,015) are significantly related to examination of VIA and factor is not related to examination of VIA is education, job, knowledge and family support. It evidence to improve health promotion programs socialization and counseling for mothers who visit the Cibinong Health Center. Keywords: women, cervical cancer, Visual Inspection Acetic Acid (VIA)


2021 ◽  
Vol 5 (1) ◽  
pp. 20
Author(s):  
Lusiana El Sinta B ◽  
Laila Rahmi ◽  
Uliy Iffah

Cervical cancer is the fourth most common cancer in women with a mortality rate of 6.8% (WHO, 2015; Globocan, 2012). The incidence of cervical cancer ranks second after breast cancer in Southeast Asia and Indonesia. Based on data from the Republic of Indonesia Ministry of Health 2015, cervical cancer is the cancer with the highest prevalence of 0.8 per 1000 population (Ministry of Health Republic of Indonesia, 2015). The high prevalence of cancer in Indonesia requires prevention and early detection by health service providers. The purpose of this study was to determine the factors that influence the inspection of Acetic Acid Visual Inspection (IVA) in Padang City.This type of research is quantitative with cross sectional design. The study was conducted at the Padang City Health Center in April-November 2019. The population was all women aged 30-50 years who were at the Padang City Health Center, amounting to 10,670 people, with a sample of 73 people taken by consecutive sampling technique. Data were collected by questionnaire and analyzed by univariate and bivariate analysis.More than half (64.4%) of women of childbearing age (WUS) have never had an IVA examination, more than half (58.9%) of women have a risk age, less than half (39.7%) women have low levels of education , more than half (60.3%) WUS with working status, there was no relationship between the age of WUS with IVA examination (p value = 0.182), there was a relationship between WUS education level and IVA examination (p value = 0.031), there was no relationship between the status of WUS work and IVA examination (p value = 0.404). It is expected that officials and leaders of puskesmas will develop more attractive ways to be able to convince and increase awareness and concern of the WUS themselves in conducting IVA examinations.


2020 ◽  
Vol 7 (1) ◽  
pp. 044-049
Author(s):  
Laily Prima Monica ◽  
Maria Ulfa

Cervical cancer is a malignant tumor that grows in the uterus / cervix which is the lowest part of the uterine core and is attached to the top of the vagina. The high incidence of cervical cancer in Indonesia is due to a lack of knowledge and perception of women to prevent the development of cervical cancer. The incomprehensive information about IVA test exposure is as the cause of the women didn't want to do the test. Lack of knowledge about the process of IVA test, feel fear and shame including feeling against to religion principles as the inhibitor factors to do test.  Method :The research design uses correlational design with a cross-sectional approach. The study population is 30 respondents and the sample consisted of 27 respondents using purposive sampling technique. Data were analyzed using Spearman rank. Results: The research data showed that there was a relationship between the level of perception of mothers about cervical cancer and the attitude of mothers to carry out the IVA test (Visual Inspection with Acetic Acid) p value = 0,000, so the p value = 0,000 <0.05 while r = 0.678. The relationship of perception with attitude shows that more than half of the respondents 66% have a  positive perception in early detection of cervical cancer and  they are positive about IVA (Visual Inspection with Acetic Acid).


2020 ◽  
Vol 9 (2) ◽  
pp. 21
Author(s):  
Sitti Mukarramah ◽  
Subriah Subriah ◽  
Wirawati Amin ◽  
Humrah Humrah

Cervical cancer is the number one killer of women in the world caused by the Human Papilomma Virus. One of the early detection of cervical cancer by checking Visual Inspection with Acetic Acid (VIA) is a simple way to detect cervical abnormalities. Knowledge of cervical cancer is one of the factors influencing WCBA behavior in conducting VIA examinations. This study aims to determine the relationship between WUS knowledge on cervical cancer with early detection examination behavior using VIA in Maradekaya Village. The research sample was 59 respondents with random sampling technique and a cross-sectional research design. The results showed that the respondents' knowledge about cervical cancer was included in the "tofu" category as many as 55 respondents (93.2%) and "do not know" category were 4 respondents (6.8%), respondents who did VIA examination were 22 respondents (37.3%) and those who did not perform VIA examination were 37 respondents (62.7%). Chi-square test with 95% CI showed a p-value of 0.521 (P> 0.05). These results indicate that there is no relationship between WCBA knowledge about cervical cancer with early detection using VIA in Maradekaya Village. Additional conclusions that can influence behavior it is culture.Kanker serviks adalah pembunuh wanita nomor satu di dunia yang disebabkan oleh Human Papilomma Virus. Salah satu deteksi dini kanker serviks dengan pemeriksaan Visual Inspection with Acetic Acid (VIA) merupakan cara sederhana untuk mendeteksi kelainan serviks. Pengetahuan tentang kanker serviks merupakan salah satu faktor yang mempengaruhi perilaku WCBA dalam melakukan pemeriksaan VIA. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan WUS tentang kanker serviks dengan perilaku pemeriksaan deteksi dini menggunakan VIA di Desa Maradekaya. Sampel penelitian sebanyak 59 responden dengan teknik random sampling dan desain penelitian cross-sectional. Hasil penelitian menunjukkan bahwa pengetahuan responden tentang kanker serviks termasuk dalam kategori “tahu” sebanyak 55 responden (93,2%) dan kategori “tidak tahu” sebanyak 4 responden (6,8%), responden yang melakukan pemeriksaan VIA sebanyak 22 responden. responden (37,3%) dan yang tidak melakukan pemeriksaan VIA sebanyak 37 responden (62,7%). Uji Chi-square dengan 95% CI menunjukkan nilai p 0,521 (P> 0,05). Hasil ini menunjukkan bahwa tidak ada hubungan antara pengetahuan WCBA tentang kanker serviks dengan deteksi dini menggunakan VIA di Desa Maradekaya. Kesimpulan tambahan yang dapat mempengaruhi perilaku itu adalah budaya.


Author(s):  
Zeina A Munim Al-Thanoon ◽  
Zeina A Munim Al-Thanoon ◽  
Mustafa Basil ◽  
Nasih A Al-Kazzaz

Iron chelation therapy with deferoxamine (DFO),the current standard for the treatment of iron overload in patients with betathalassemia,requires regular subcutaneous or intravenous infusions. This can lead to reduced quality of life and poor adherence,resulting in increased morbidity and mortality in iron-overloaded patients with beta-thalassemia. Deferasirox (DFX) is an orally administered iron chelator that has been approved for use in many countries. The requirement of an effective,well tolerated iron chelator with a less demanding mode of administration has led to the development of deferasirox. The present study was aimed to compare the satisfaction and compliance with deferoxamine versus deferasirox (Exjade®),a novel oral iron chelator in patients with transfusion - dependent beta- thalassemia. A cross-sectional,single-center investigation study was carried out in the Thalassemia Center of Ibn-Atheer Teaching Hospital in Nineveh province,Iraq. One hundred and eight thalassemic patients aged between 2- 20 years old having received multiple blood transfusions and a serum ferritin greater than 1500 ng/ml. Patients were randomised into two groups. Group 1 received deferoxamine at a dose of 20-50mg/kg/day and group 2 received deferasirox at the dose of 10-30 mg/kg/day. Another 56 apparently healthy volunteers were used as a control group. The assessment of chelation was done during the period between November 2013 and February 2014 by measurement of serum ferritin. Satisfaction and compliance was assessed by using a special questionnaire prepared by the researcher. Out of the 108 thalassemic patients enrolled there was no discontinuation in treatment with the two drugs under study. The serum ferritin did not change significantly in any of the chelation groups. In comparison with the patients who were treated with DFO,those receiving DFX reported a significantly higher rate of compliance and satisfaction (P < 0.05). However,no significant difference was observed between the two groups regarding their satisfaction (P > 0.05).Compliance with deferasirox (50 %) was more than that with deferoxamine (20 %). Satisfaction with deferoxamine was significantly lower than deferasirox (p= 0.00).


2018 ◽  
Vol 1 (2) ◽  
pp. 114
Author(s):  
Wahdaniah Wahdaniah ◽  
Sri Tumpuk

Abstract: Routine blood examination is the earliest blood test or screening test to determine the diagnosis of an abnormality. Blood easily froze if it is outside the body and can be prevented by the addition of anticoagulants, one of which Ethylene Diamine Tetra Acetate (EDTA). Currently available vacuum tubes containing EDTA anticoagulants in the form of K2EDTA and K3EDTA. K3EDTA is usually a salt that has better stability than other EDTA salts because it shows a pH approaching a blood pH of about 6.4. The purpose of this research is to know the difference of erythrocyte index results include MCH, MCV and MCHC using K3EDTA anticoagulant with K2EDTA. This research is a cross sectional design. This study used venous blood samples mixed with K2EDTA anticoagulant and venous blood mixed with K3EDTA anticoagulants, each of 30 samples. Data were collected and analyzed using paired different test. Based on data analysis that has been done on MCH examination, p value <0,05 then there is a significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value. Then on the examination of MCV and MCHC obtained p value <0.05 then there is no significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value.Abstrak: Pemeriksaan darah rutin merupakan pemeriksaan darah yang paling awal atau screening test untuk mengetahui diagnosis suatu kelainan. Darah mudah membeku jika berada diluar tubuh dan bisa dicegah dengan penambahan antikoagulan, salah satunya Ethylene Diamine Tetra Acetate (EDTA). Dewasa ini telah tersedia tabung vakum yang sudah berisi antikoagulan EDTA dalam bentuk  K2EDTA dan  K3EDTA. K3EDTA  biasanya berupa garam yang mempunyai stabilitas yang lebih baik dari garam EDTA yang lain karena menunjukkan pH yang mendekati pH darah yaitu sekitar 6,4. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan hasil indeks eritrosit meliputi MCH, MCV dan MCHC menggunakan antikoagulan K3EDTA dengan K2EDTA. Penelitian ini merupakan penelitian dengan desain cross sectional. Penelitian ini menggunakan sampel darah vena yang dicampur dengan antikoagulan K2EDTA dan darah vena yang dicampur dengan antikoagulan K3EDTA, masing-masing sebanyak 30 sampel. Data dikumpulkan dan dianalisis menggunakan uji beda berpasangan. Berdasarkan analisis data yang telah dilakukan pada pemeriksaan MCH didapatkan nilai p < 0,05 maka ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit. Kemudian pada pemeriksaan MCV dan MCHC didapatkan nilai p < 0,05 maka tidak ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit.


2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Sahar Mahmoud Shawky ◽  
Reeham Abdel Aziz Abdel Hamid ◽  
Lina Essam Khedr

Abstract Background Pruritus is a common and often distressing symptom in patients with chronic kidney disease. Though the pathogenesis of uremic pruritus remains poorly understood, systemic inflammation has presented itself as one of the possible explanations. High blood lead levels (BLLs) have been noted to be associated with inflammation and poor nutritional status in hemodialysis patients. Our aim is to study the relation between blood lead levels and uremic pruritus. This is a cross-sectional study that enrolled 50 patients; all were on regular hemodialysis 3 times per week for at least 6 months. Patients were divided into 2 groups, group 1 (n =10) with no pruritus and group 2 (n=40) with varying degrees of pruritus. Group 2 was further divided according to intensity of pruritus by visual analog score (VAS) into mild (n=10), moderate (n=20), and severe pruritus (n=10). Results There was a significant difference in serum lead levels and ferritin levels between groups 1 and 2 (p value < 0.01 and < 0.05, respectively). There was a statistically significant difference in serum lead levels in the groups with varying intensity of pruritus, having higher serum lead levels in patients who exhibited severe pruritus (p value < 0.005) Moreover, a statistically significant relation between elevated blood lead levels and the duration of dialysis was observed in this study. Conclusion Uremic pruritus is a multi-factorial phenomenon, and our study showed that blood lead levels in hemodialysis patients might be associated with increased intensity of pruritus.


Work ◽  
2021 ◽  
pp. 1-8
Author(s):  
Javad vatani ◽  
Zahra Khanikosarkhizi ◽  
Mohammad Ali Shahabi Rabori ◽  
mohammad khandan ◽  
Mohsen aminizadeh ◽  
...  

BACKGROUND: Safety climate is a common insight of staff that indicates individuals’ attitudes toward safety and priority of safety at work. OBJECTIVES: Nursing is a risky job where paying attention to safety is crucial. The assessment of the safety climate is one of the methods to measure the safety conditions in this occupation. The aim of this study was to assess the safety climate of rehabilitation nurses working in hospitals in Tehran. METHODS: This is a cross-sectional study which was carried out on 140 rehabilitation nurses selected from all hospitals and clinics in Tehran in 2019. To collect the required data, a two-section questionnaire was used. The first section was related to demographic factors and the second part (22 statements) was to measure the safety climate using nurses’ safety climate assessment questionnaire. The collected data were analyzed by SPSS V16 using independent t-test, ANOVA, Kruskal-Wallis and Mann-Whitney U test at the 5% level. RESULTS: Findings showed that the total mean of safety climate was 3.06±0.56. According to the results, a significant difference was found between the positive and negative satisfaction of nurses with safety climates (P-value = 0.03), communication with nurses (P-value = 0.01) and supervisors’ attitude (P-value = 0.02). Furthermore, a significant difference in safety climate between the individual with the second job and the individual without second could be observed (P-value = 0.01). CONCLUSIONS: The results indicated that the safety climate was not at an acceptable level. Thus, it is essential to introduce safety training courses (e.g. safety, work-rest balance, and so on) and to improve the safety performance at work.


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