On the Pituitary of the Perch (Peroa Fluviatilis)

1942 ◽  
Vol s2-83 (331) ◽  
pp. 299-316
Author(s):  
T. KERR
Keyword(s):  
Connective Tissue ◽  
Blood Vessels ◽  
Perca Fluviatilis ◽  
Cell Types ◽  
Anterior Lobe ◽  
Intermediate Lobe ◽  
General Description ◽  
Perch Perca Fluviatilis ◽  
Higher Types ◽  
Different Cell Types

1. A general description is given of the pituitary of the perch (Perca fluviatilis L.), and histological details of its various parts. The subdivisions of the glandular component are confluent with each other but distinguished by their different cell types. The nervous lobe makes contact with all three of the subdivisions, but is separated from them by a layer of connective tissue, incomplete in particular areas. 2. The anterior glandular region (anterior lobe) has an anterior chromophil and a posterior chromophobe zone. The middle glandular region (transitional lobe) possesses brightly staining acidophils and basophils as well as chromophobes. The acidophils form a dorsal sheet, deeply indented by processes of the nervous lobe, the basophils lie ventrally and posteriorly, and chromophobes are common towards the extremities of the indentations. The posterior glandular region (intermediate lobe) is elaborately penetrated by nervous lobe processes; the cells are small and consist of amphiphils, dull basophils, and occasional dull acidophils. The possible homologies of these regions to the lobes of higher types are discussed. The nervous lobe is of loose glial tissue with many nuclei and blood vessels and some reticular and collagenous fibres. 3. Strongly acidophil spheres of various sizes and in various numbers occur in the middle glandular region. They originate in ‘sphere cells’ resembling eosinophil leucocytes and after enlarging become free in the tissues of the region. Later they appear to pass into the posterior processes of the nervous lobe to be the larger bodies of the Herring material. Finally these larger elements appear to break down to form a fine granulation, whose further fate could not be followed.

scholarly journals Immunocytochemical demonstration of tissue-type plasminogen activator in endocrine cells of the rat pituitary gland.

1985 ◽  
Vol 101 (1) ◽  
pp. 305-311 ◽  
Author(s):  
P Kristensen ◽  
L S Nielsen ◽  
J Grøndahl-Hansen ◽  
P B Andresen ◽  
L I Larsson ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Pituitary Gland ◽  
Endocrine Cells ◽  
Large Population ◽  
Cell Types ◽  
Anterior Lobe ◽  
Tissue Type ◽  
Intermediate Lobe ◽  
Posterior Lobe ◽  
Rat Pituitary

We immunocytochemically stained rat pituitary glands using antibodies against plasminogen activators of the tissue type (t-PA) and the urokinase type (u-PA). A large population of endocrine cells in the anterior lobe of the gland displayed intense cytoplasmic immunoreactivity with anti-t-PA. In some areas of the intermediate lobe we found a weak staining, and we observed weakly staining granular structures in the posterior lobe. Controls included absorption of the antibodies with highly purified t-PA. In addition, SDS PAGE followed by immunoblotting of pituitary gland extracts revealed only one band with an electrophoretic mobility similar to that of t-PA when stained with anti-t-PA IgG. No u-PA immunoreactivity was detected in the rat pituitary gland. Sequential staining experiments using antibodies against growth hormone and t-PA demonstrated that the t-PA-immunoreactive cells constitute a large subpopulation of the growth hormone-containing cells. These findings represent the first direct evidence for the presence of t-PA in cell types other than endothelial cells in the intact normal organism. In this article we discuss the implications of the results for a possible role of t-PA in the posttranslational processing of prohormones.

scholarly journals A Rare Case of Third Ventricular Glioblastoma

2021 ◽  
Author(s):  
Asmira Gacic ◽  
Hakija Beculic ◽  
Rasim Skomorac ◽  
Alma Efendic
Keyword(s):  
Spinal Cord ◽  
Glioblastoma Multiforme ◽  
Blood Vessels ◽  
Rare Case ◽  
Third Ventricle ◽  
Cell Types ◽  
The Third ◽  
Different Cell Types ◽  
Brain And Spinal Cord ◽  
The Brain

Glioblastoma, also known as glioblastoma multiforme, is an aggressive type of cancer that is made up of abnormal astrocytic cells, but also contain a mixture of different cell types (including blood vessels) and areas of necrosis. It is often seen in the brain and spinal cord, but glioblastomas are rarely found in the third ventricle. In this case, it was diagnosed in a 22-year-old male patient and we intended to draw

CHARACTERISTICS OF PERCH (PERCA FLUVIATILIS L.) POPULATION OF THE CENTRAL PART OF THE KUIBYSHEV RESERVOIR

2018 ◽  
pp. 76-83
Author(s):  
Tamara Alekseevna Telezhnikova ◽  
Rustem Rashitovich Saifullin ◽  
Anton Valentinovich Granin ◽  
Ildar Rafailevich Shakirov
Keyword(s):  
Reproductive Function ◽  
Perca Fluviatilis ◽  
Fish Mortality ◽  
General Description ◽  
Kuibyshev Reservoir ◽  
State Research Institute ◽  
Perch Perca Fluviatilis ◽  
Total Fish ◽  
The Republic ◽  
Comparison Of The Results

The article gives general description of perch population of the Kuybyshev reservoir according to the net fishing in 2014-2017, as well as comparison of the results with literature data. The maximum perch specimen caught during the years of research had a body length 40 cm, weight over 1.5 kg and age of 13 years. Maximum life span of perch in the Kuibyshev reservoir has been calculated, which is 17 years. The prevalence of females over males in the populations of perches with the ratio 2:1, the average age of sexual maturity of females and males coincides and makes 3 years. The decay of the reproductive function of the perch occurs after 5 years. Massive spawning of perch in 2016 was observed in the water with temperature 10°C. The maximum value of individual absolute fertility in perch was 370.3 thousand eggs. Differences in the rate of perch growth in various parts of the Kuibyshev reservoir were revealed. A total fish mortality rate made 0.6. The calculation of the catch of perch by the amateur fishermen was made within the Republic of Tatarstan, which amounted to 1.6 tons in 2016. The data of the Tatar department of the State research institute of fisheries "GosNIORH" on the commercial catches of perch in the Kuibyshev reservoir have been presented.

Neurosecretory innervation of the pituitary of the eels anguilla and conger II. The structure and innervation of the pars distalis at different stages of the life-cycle

1966 ◽  
Vol 250 (768) ◽  
pp. 329-342 ◽  
Keyword(s):  
Life Cycle ◽  
Endocrine Cells ◽  
Functional Relationship ◽  
Cell Types ◽  
Intermediate Lobe ◽  
Special Importance ◽  
Pars Distalis ◽  
Distinct Cell ◽  
Different Cell Types ◽  
The Relationship

A number of distinct cell types may be recognized in the pituitary of the eel at the level of ultra-­structure by reason of the specificity of the size and electron-density of the granules they contain. The size of the granules and changes in the different cell types at different stages of the life-cycle permit a tentative identification in terms of function. The pars distalis of the eel pituitary receives the greater part of its innervation from the nucleus lateralis tuberis by Type B neurosecretory fibres (Knowles 1965 a ), which do not stain with the so-called neurosecretory stains, but which nevertheless contain elementary neurosecretory vesicles. Type A, or classical, neurosecretory innervation is also present and seems to be of special importance at certain stages of the life-cycle. The possible function of these two forms of neurosecretory inner­- vation is discussed. The relationship between the intrinsic endocrine cells of the pars distalis and their neurosecretory innervation is fundamentally similar, at the level of ultrastructure, to that of the neuro-intermediate lobe. There are no direct contacts between the neurosecretory fibres and the intrinsic endocrine cells, but the proximity of the fibre terminals ( ca. 2000 to 4000 A) to endocrine cells indicates a functional relationship between these two elements of the pituitary of the eel.

Study of the Molecular Architecture of Keratin Filaments by Electron Microscopy

1982 ◽  
Vol 40 ◽  
pp. 118-119
Author(s):  
U. Aebi ◽  
P. Rew ◽  
T.-T. Sun
Keyword(s):  
Electron Microscopy ◽  
Structural Organization ◽  
Cell Types ◽  
Structural Features ◽  
Molecular Architecture ◽  
The Past ◽  
Keratin Filaments ◽  
Different Types ◽  
10 Nm Filaments ◽  
Different Cell Types

Various types of intermediate-sized (10-nm) filaments have been found and described in many different cell types during the past few years. Despite the differences in the chemical composition among the different types of filaments, they all yield common structural features: they are usually up to several microns long and have a diameter of 7 to 10 nm; there is evidence that they are made of several 2 to 3.5 nm wide protofilaments which are helically wound around each other; the secondary structure of the polypeptides constituting the filaments is rich in ∞-helix. However a detailed description of their structural organization is lacking to date.

Processing and Characterization of Recombinant von Willebrand Factor Expressed in Different Cell Types Using a Vaccinia Virus Vector

1992 ◽  
Vol 67 (01) ◽  
pp. 154-160 ◽  
Author(s):  
P Meulien ◽  
M Nishino ◽  
C Mazurier ◽  
K Dott ◽  
G Piétu ◽  
...  
Keyword(s):  
Vaccinia Virus ◽  
Von Willebrand Factor ◽  
Human Fibroblasts ◽  
Active Form ◽  
Cell Types ◽  
Biologically Active ◽  
L Cells ◽  
Von Willebrand ◽  
Different Cell Types ◽  
Willebrand Factor

SummaryThe cloning of the cDNA encoding von Willebrand factor (vWF) has revealed that it is synthesized as a large precursor (pre-pro-vWF) molecule and it is now clear that the prosequence or vWAgll is responsible for the intracellular multimerization of vWF. We have cloned the complete vWF cDNA and expressed it using a recombinant vaccinia virus as vector. We have characterized the structure and function of the recombinant vWF (rvWF) secreted from five different cell types: baby hamster kidney (BHK), Chinese hamster ovary (CHO), human fibroblasts (143B), mouse fibroblasts (L) and primary embryonic chicken cells. Forty-eight hours after infection, the quantity of vWF antigen found in the cell supernatant varied from 3 to 12 U/dl depending on the cell type. By SDS-agarose gel electrophoresis, the percentage of high molecular weight forms of vWF varied from 39 to 49% relative to normal plasma for BHK, CHO, 143B and chicken cells but was less than 10% for L cells. In all cell types, the two anodic subbands of each multimer were missing. The two cathodic subbands were easily detected only in BHK and L cells. By SDS-PAGE of reduced samples, pro-vWF was present in similar quantity to the fully processed vWF subunit in L cells, present in moderate amounts in BHK and CHO and in very low amounts in 143B and chicken cells. rvWF from all cells bound to collagen and to platelets in the presence of ristocetin, the latter showing a high correlation between binding efficiency and degree of multimerization. rvWF from all cells was also shown to bind to purified FVIII and in this case binding appeared to be independent of the degree of multimerization. We conclude that whereas vWF is naturally synthesized only by endothelial cells and megakaryocytes, it can be expressed in a biologically active form from various other cell types.

Role of Transcriptional Read-Through in PRE Activity in Drosophila melanogaster

Acta Naturae ◽  
2016 ◽  
Vol 8 (2) ◽  
pp. 79-86 ◽  
Author(s):  
P. V. Elizar’ev ◽  
D. V. Lomaev ◽  
D. A. Chetverina ◽  
P. G. Georgiev ◽  
M. M. Erokhin
Keyword(s):  
Dna Sequences ◽  
Cell Types ◽  
Transcription Terminator ◽  
Response Elements ◽  
Polycomb Response Elements ◽  
The Individual ◽  
Multicellular Organisms ◽  
Different Cell Types ◽  
Main Factor

Maintenance of the individual patterns of gene expression in different cell types is required for the differentiation and development of multicellular organisms. Expression of many genes is controlled by Polycomb (PcG) and Trithorax (TrxG) group proteins that act through association with chromatin. PcG/TrxG are assembled on the DNA sequences termed PREs (Polycomb Response Elements), the activity of which can be modulated and switched from repression to activation. In this study, we analyzed the influence of transcriptional read-through on PRE activity switch mediated by the yeast activator GAL4. We show that a transcription terminator inserted between the promoter and PRE doesnt prevent switching of PRE activity from repression to activation. We demonstrate that, independently of PRE orientation, high levels of transcription fail to dislodge PcG/TrxG proteins from PRE in the absence of a terminator. Thus, transcription is not the main factor required for PRE activity switch.

Consumption of plant material by perch (Perca fluviatilis)

2016 ◽  
Vol 65 (2) ◽  
pp. 95-97 ◽  
Author(s):  
Tomáš Zapletal ◽  
Zdeněk Adámek ◽  
Pavel Jurajda ◽  
Kevin Roche ◽  
Lucie Všetičková ◽  
...  
Keyword(s):  
Plant Material ◽  
Perca Fluviatilis ◽  
Perch Perca Fluviatilis

MAPK: A Key Player in the Development and Progression of Stroke

2020 ◽  
Vol 19 (4) ◽  
pp. 248-256
Author(s):  
Yangmin Zheng ◽  
Ziping Han ◽  
Haiping Zhao ◽  
Yumin Luo
Keyword(s):  
Ischemic Stroke ◽  
Signaling Pathway ◽  
Complex Disease ◽  
Therapeutic Targets ◽  
Cell Types ◽  
Mapk Signaling ◽  
Mapk Signaling Pathway ◽  
Effective Prevention ◽  
Prevention And Treatment ◽  
Different Cell Types

Conclusion: Stroke is a complex disease caused by genetic and environmental factors, and its etiological mechanism has not been fully clarified yet, which brings great challenges to its effective prevention and treatment. MAPK signaling pathway regulates gene expression of eukaryotic cells and basic cellular processes such as cell proliferation, differentiation, migration, metabolism and apoptosis, which are considered as therapeutic targets for many diseases. Up to now, mounting evidence has shown that MAPK signaling pathway is involved in the pathogenesis and development of ischemic stroke. However, the upstream kinase and downstream kinase of MAPK signaling pathway are complex and the influencing factors are numerous, the exact role of MAPK signaling pathway in the pathogenesis of ischemic stroke has not been fully elucidated. MAPK signaling molecules in different cell types in the brain respond variously after stroke injury, therefore, the present review article is committed to summarizing the pathological process of different cell types participating in stroke, discussed the mechanism of MAPK participating in stroke. We further elucidated that MAPK signaling pathway molecules can be used as therapeutic targets for stroke, thus promoting the prevention and treatment of stroke.

Sign in / Sign up

Export Citation Format

Share Document