scholarly journals The prevalence and clinical significance of anemia in patients hospitalized with acute heart failure

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 1006
Author(s):  
Attila Frigy ◽  
Zoltán Fogarasi ◽  
Ildikó Kocsis ◽  
Lehel Máthé ◽  
Előd Nagy
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Acute Heart Failure ◽  
Clinical Picture ◽  
Loop Diuretic ◽  
High Dose ◽  
Chi Square ◽  
Frequent Finding ◽  
Chi Square Test ◽  
Prevalence Of Anemia

Abstract In a cohort of patients hospitalized with acute heart failure (AHF) the prevalence of anemia and the existence of a correlation between anemia and the severity of the clinical picture were assessed. Methods. 50 consecutive patients (34 men, 16 women, mean age 67.5 years) hospitalized with AHF were enrolled.  Statistical analysis was performed using a chi-square test, for studying univariate correlation between anemia and the presence of diverse parameters reflecting the severity and prognosis of AHF (α=0.05). Results. 21 patients (14 men, 7 women, mean age 69.6 years), representing 42%, had anemia (Hb<12 g/dl) at admission. Comparing patients with and without anemia there were no significant differences regarding age,  gender,  presence of atrial fibrillation (p=0.75), diabetes (p=1), ischemic heart disease (p=0.9), ejection fraction < 35% (p=1), hypotension at admission (p=0.34), tachycardia>100 b/min at admission (p=0.75), creatinine level >1.5mg% (p=0.12), and need of high dose of loop diuretic >80 mg/day (p=0.23). Conclusions. Anemia is a frequent finding in patients hospitalized with AHF. The presence of anemia was not correlated with other factors related to AHF severity and prognosis. This fact suggests its independent role in influencing the clinical picture and prognosis.

scholarly journals Research Article. Characteristics of Sleep Apnea Assessed Before Discharge in Patients Hospitalized with Acute Heart Failure

2017 ◽  
Vol 63 (1) ◽  
pp. 19-22
Author(s):  
Ildikó Kocsis ◽  
Lajos Fehérvári ◽  
Zoltán Fogarasi ◽  
István Adorján Szabó ◽  
Attila Frigy
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Sleep Apnea ◽  
Acute Heart Failure ◽  
Stable Condition ◽  
Descriptive Statistics ◽  
Chi Square ◽  
Related Factors ◽  
Research Article ◽  
Chi Square Test

AbstractObjectives. Evaluation of the characteristics of sleep apnea (SA) in patients hospitalized with acute heart failure, considering that undiagnosed SA could contribute to early rehospitalization. Methods. 56 consecutive patients (13 women, 43 men, mean age 63.12 years) with acute heart failure, in stable condition, underwent nocturnal polygraphy before hospital discharge. The type and severity of SA was determined. Besides descriptive statistics, correlations between the severity of SA and clinical and paraclinical characteristics were also analyzed (t-test, chi-square test, significancy at alpha < 0.05). Results. 12 (21.4%) subjects were free of SA (AHI - apnea-hipopnea index <5/h), 15 (26.7%) had mild SA (AHI=5-14/h), 17 (30.3%) had moderate SA (AHI 15-30/h), and 12 (21.4 %) had severe SA (AHI>30/h). The apnea was predominantly obstructive (32 cases vs. 12 with central SA). Comparing the patients with mild or no SA with those with severe SA, we did not find statistically significant correlations (p>0.05) between the severity of SA and the majority of main clinical and paraclinical characteristics - age, sex, BMI, cardiac substrates of heart failure, comorbidities. Paradoxically, arterial hypertension (p=0.028) and atrial fibrillation (p=0.041) were significantly more prevalent in the group with mild or no SA. Conclusions. Before discharge, in the majority of patients hospitalized with acute heart failure moderate and severe SA is present, and is not related to the majority of patient related factors. Finding of significant SA in this setting is important, because its therapy could play an important role in preventing readmissions and improving prognosis.

scholarly journals The prevalence and clinical significance of anemia in patients hospitalized with acute heart failure

F1000Research ◽  
2017 ◽  
Vol 5 ◽  
pp. 1006
Author(s):  
Attila Frigy ◽  
Zoltán Fogarasi ◽  
Ildikó Kocsis ◽  
Lehel Máthé ◽  
Előd Nagy
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Clinical Laboratory ◽  
Renal Perfusion ◽  
Multiple Regression Model ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
High Dose ◽  
Ventricular Ejection Fraction ◽  
Prevalence Of Anemia

Abstract: In a cohort of patients hospitalized with acute heart failure (AHF) the prevalence of anemia and the existence of a correlation between anemia and the severity of the clinical picture were assessed. Methods: 50 consecutive patients (34 men, 16 women, mean age 67.5 years) hospitalized with AHF were enrolled.  Statistical analysis was performed for studying correlations between anemia and the presence/levels of diverse parameters (clinical, laboratory, echocardiographic, treatment related)  reflecting the severity and prognosis of AHF (α=0.05). Results: 21 patients (14 men, 7 women, mean age 69.6 years), representing 42%, had anemia  at admission. Comparing patients with and without anemia there were no significant differences regarding age,  gender,  presence of atrial fibrillation (p=0.75), diabetes (p=1), ischemic heart disease (p=0.9), left ventricular ejection fraction (EF) (p=1), hypotension (p=0.34) and tachycardia>100 b/min at admission (p=0.75), level of eGFR (p=0.72), and need of high dose (>80 mg/day)  loop diuretic (p=0.23). However, EF showed a significant positive correlation with eGFR only in AHF patients with anemia (r=0,65, p=0.001). In a multiple regression model, EF had a significant effect on the eGFR quartiles (p=0,004). Conclusions: Anemia is a frequent finding in patients hospitalized with AHF. The presence of anemia was not correlated with other factors related to AHF severity and prognosis. However, a low EF associated with low eGFR was characteristic for patients with anemia, suggesting that the decrease of renal perfusion by low cardiac output further aggravates anemia on the background of chronic kidney disease.

scholarly journals Loop Diuretic Administration in Patients with Acute Heart Failure and Reduced Systolic Function: Effects of Different Intravenous Diuretic Doses and Diuretic Response Measurements

2019 ◽  
Vol 8 (11) ◽  
pp. 1854
Author(s):  
Gaetano Ruocco ◽  
Mauro Feola ◽  
Ranuccio Nuti ◽  
Lorenzo Luschi ◽  
Isabella Evangelista ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Poor Prognosis ◽  
Dose Group ◽  
Loop Diuretic ◽  
Systolic Function ◽  
Multivariable Analysis ◽  
High Dose ◽  
Diuretic Response ◽  
Infusion Period

Background: Despite the fact that loop diuretics are a landmark in acute heart failure (AHF) treatment, few trials exist that evaluate whether the duration and timing of their administration and drug amount affect outcome. In this study, we sought to evaluate different loop diuretic infusion doses in relation to outcome and to diuretic response (DR), which was serially measured during hospitalization. Methods: This is a post-hoc analysis of a DIUR-HF trial. We divided our sample on the basis of intravenous diuretic dose during hospitalization. Patients taking less than 125 mg of intravenous furosemide (median value) were included in the low dose group (LD), patients with a diuretic amount above this threshold were inserted in the high dose group (HD). The DR formula was defined as weight loss/40 mg daily of furosemide and it was measured during the first 24 h, 72 h, and over the whole infusion period. Outcome was considered as death due to cardiovascular causes or heart failure hospitalization. Results: One hundred and twenty-one AHF patients with reduced ejection fractions (EF) were evaluated. The cardiovascular (CV) death/heart failure (HF) re-hospitalization rate was significantly higher in the HD group compared to the LD group (75% vs. 22%; p < 0.001). Both low DR, measured during the entire infusion period (HR 3.25 (CI: 1.92–5.50); p < 0.001) and the intravenous diuretic HD (HR 5.43 [CI: 2.82–10.45]; p < 0.001) were related to outcome occurrence. Multivariable analysis showed that DR (HR 3.01 (1.36–6.65); p = 0.006), intravenous diuretic HD (HR 2.83 (1.24–6.42); p=0.01) and worsening renal function (WRF) (HR 2.21 (1.14–4.28); p = 0.01) were related to poor prognosis. Conclusions: HD intravenous loop diuretic administration is associated with poor prognosis and less DR. Low DR measured during the whole intravenous administration better predicts outcome compared to DR measured in the early phases. ClinicalTrials.gov Acronym and Identifier Number: DIUR-HF; NCT01441245; registered on 23 September 2011.

scholarly journals Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial

2017 ◽  
Vol 106 (6) ◽  
pp. 444-456 ◽  
Author(s):  
Gerasimos Filippatos ◽  
Dimitrios Farmakis ◽  
Marco Metra ◽  
Gad Cotter ◽  
Beth A. Davison ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Acute Heart Failure ◽  
Secondary Analysis ◽  
Heart Failure Patients

OC03_03 Prevalence, Characteristics and Outcomes of Atrial Fibrillation in the Sub Saharan Acute Heart Failure (Thesus -HF) Registry

Global Heart ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e4
Author(s):  
M.U. Sani ◽  
O.S. Ogah ◽  
B.A. Davison ◽  
G. otter ◽  
A. Damasceno ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Acute Heart Failure ◽  
Sub Saharan

Hubungan Kecacingan dengan Kejadian Anemia pada Anak Sekolah Dasar di Kecamatan Tanjung Senang Bandar Lampung

2021 ◽  
Vol 1 (4) ◽  
pp. 445-452
Author(s):  
Rita Agustina ◽  
Tusy Triwahyuni ◽  
Devita Febriani Putri ◽  
Nindi Destiani
Keyword(s):  
Elementary School ◽  
School Children ◽  
Elementary School Children ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
The World ◽  
Chi Square Test ◽  
Quota Sampling ◽  
Prevalence Of Anemia

ABSTRACT: RELATIONSHIP WITH ANEMIA IN ELEMENTARY CHILDREN IN TANJUNG SENANG REGENCY, BANDAR LAMPUNG Background: Anemia is a condition in which the number of red blood cells or the hemoglobin concentration in them is less than normal. WHO in the World Wide Prevalence of Anemia reports that the total population of the world who suffer from anemia is 1.62 billion people with a prevalence in primary school children (25.4%) and 305 million school children worldwide suffer from anemia. In general, the cause of anemia is nutritional deficiencies, especially iron deficiency and parasitic infections such as worms. Worms is an infectious disease caused by parasites in the form of worms. Objective: Knowing the Relation between Worms and Anemia in Elementary School Children in In Tanjung Senang District Bandar Lampung in 2020. Method: This type of research is quantitative research and analytical observational research methods with a cross sectional approach with the Chi Square test. Sampling was done using Quota Sampling. The sample in this study were 63 people. Results: The results of the Chi Square test showed p-value = 0.000, which is less than the significance value of 5% (0.05), this shows that there is a significant relationship between worms and anemia in elementary school children in Tanjung Senang, Bandar Lampung, in 2020. Conclusion: There is a significant relationship between helminths and the incidence of anemia in elementary school children in Tanjung Senang, Bandar Lampung, in 2020. Keywords: Worms, Anemia Incidence  ABSTRAK: HUBUNGAN KECACINGAN DENGAN KEJADIAN ANEMIA PADA ANAK SEKOLAH DASAR DI KECAMATAN TANJUNG SENANG BANDAR LAMPUNG Pendahuluan: Anemia merupakan suatu kondisi dimana jumlah sel darah merah atau konsentrasi hemoglobin di dalamnya kurang dari biasanya. WHO dalam World wide Prevalence of Anemia melaporkan bahwa total dari keseluruhan penduduk dunia yang menderita anemia adalah 1,62 miliar orang dengan prevalensi pada anak sekolah dasar (25,4%) dan 305 juta anak sekolah di seluruh dunia menderita anemia. Pada umumnya penyebab anemia adalah kekurangan nutrisi, terutama kekurangan zat besi dan infeksi parasit seperti kecacingan. Kecacingan merupakan penyakit infeksi yang disebabkan oleh parasit berupa cacing.Tujuan: Penelitian ini bertujuan untuk mengetahui Hubungan Kecacingan Dengan Kejadian Anemia Pada Anak Sekolah Dasar di Di Kecamatan Tanjung Senang Bandar Lampung Tahun 2020. Jenis penelitian yang digunakan adalah penelitian kuantitatif dan metode penelitian analitik observasional dengan pendekatan cross sectional dengan uji Chi Square. Pengambilan sampel dilakukan dengan menggunakan Quota Sampling. Sampel pada penelitian ini sebanyak 63 orang.Hasil: Hasil uji Chi Square  menunjukkan p-value = 0.000 dimana kurang dari nilai kemaknaan yaitu 5% (0.05), hal tersebut menunjukkan terdapat hubungan yang signifikan antara kecacingan dengan kejadian anemia pada anak Sekolah Dasar di Kecamatan Tanjung Senang Bandar Lampung Tahun 2020.Kesimpulan: Kesimpulannya terdapat hubungan yang signifikan antara kecacingan dengan kejadian anemia pada anak Sekolah Dasar di Kecamatan Tanjung Senang Bandar Lampung Tahun 2020. Kata Kunci  Kecacingan, Kejadian Anemia

scholarly journals Therapeutic adherence in outpatients with heart failure registered with a community pharmacy

2012 ◽  
Vol 48 (1) ◽  
pp. 61-68
Author(s):  
Rosario Megret Despaigne ◽  
Carlos Manuel Dutok Sánchez ◽  
Alam Sarfraz
Keyword(s):  
Heart Failure ◽  
Associated Factors ◽  
Data Extraction ◽  
Health Department ◽  
Chi Square ◽  
Therapeutic Adherence ◽  
Sample Characterization ◽  
Chi Square Test ◽  
Santiago De Cuba ◽  
High Level

A transverse descriptive study was carried out, according to the classification of therapeutic compliance, to evaluate adherence in 250 patients with a diagnosis of Heart Failure, registered with the health department of the municipality of Santiago de Cuba in 2009. The sample characterization was studied, with an assessment of adherence level and possible associated factors for sex, age and toxic habits. As an instrument for the work, data extraction was scheduled and the interview was carried out at patients' homes; the results were expressed in percentage and level of influence for associated factors. This was determined using the chi-square test. In the investigated population, adherence was greater for females, for age group 67-82 years, and toxic habits were found to have prevalence. Prevailing pharmacoterapies were digoxin, chlortalidone, captopril and isosorbide dinitrate, and a high level of adherence was found, both for the pharmacological and non-pharmacological treatments, in the studied sample. A good level of therapeutic adherence was found for 63.6% of the patients, regular level of adherence was found for 32% and only 4.4% or patients presented with poor adherence. Influencing factors were: knowledge of the treatment, number of medications, frequency of administration, and satisfaction with the service of pharmaceutical care.

P6361Prognostic value of discharge heart rate in acute heart failure patients: more relevant in atrial fibrillation?

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
R Vidal-Perez ◽  
R Agra-Bermejo ◽  
D Pascual-Figal ◽  
F Gude Sampedro ◽  
C Abou Jokh ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Heart Rate ◽  
Sinus Rhythm ◽  
Acute Heart Failure ◽  
Left Ventricular Ejection ◽  
Long Term Outcomes ◽  
All Cause Mortality ◽  
One Year

Abstract Background The prognostic impact of heart rate (HR) in acute heart failure (AHF) patients is not well known especially in atrial fibrillation (AF) patients. Purpose The aim of the study was to evaluate the impact of admission HR, discharge HR, HR difference (HRD) (admission- discharge) in AHF patients with sinus rhythm (SR) or AF on long- term outcomes. Methods We included 1398 patients consecutively admitted with AHF between October 2013 and December 2014 from a national multicentric, prospective registry. Logistic regression models were used to estimate the association between admission HR, discharge HR and HR difference and one- year all-cause mortality and HF readmission. Results The mean age of the study population was 72±12 years. Of these, 594 (42.4%) were female, 655 (77.8%) were hypertensive and 655 (46.8%) had diabetes. Among all included patients, 745 (53.2%) had sinus rhythm and 653 (46.7%) had atrial fibrillation. Only discharge HR was associated with one-year all-cause mortality (Relative risk (RR)= 1.182, confidence interval (CI) 95% 1.024–1.366, p=0.022) in SR. In AF patients discharge HR was associated with one-year all-cause mortality (RR= 1.276, CI 95% 1.115–1.459, p≤0.001). We did not observe a prognostic effect of admission HR or HRD on long-term outcomes in both groups. This relationship is not dependent on left ventricular ejection fraction (Figure 1) Effect of post-discharge heart rate Conclusions In AHF patients lower discharge HR, neither the admission nor the difference, is associated with better long-term outcomes especially in AF patients Acknowledgement/Funding Heart Failure Program of the Red de Investigaciόn Cardiovascular del Instituto de Salud Carlos III, Madrid, Spain (RD12/0042) and the Fondo Europeo de

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