scholarly journals Effect of extraction method on Curcuma xanthorrhiza oleoresin using solar dryer to concentration of curcuminoid, total phenol and antioxidant activty

2017 ◽  
Vol 14 (1) ◽  
pp. 1-9
Author(s):  
THERESIA AGNIEST PRICILLA VITANTI ◽  
KAWIJI KAWIJI ◽  
EDHI NURHARTADI
Keyword(s):  
Antioxidant Activity ◽  
Extraction Method ◽  
Immersion Time ◽  
Size Variation ◽  
Extraction Process ◽  
Total Phenol ◽  
Raw Material ◽  
Powder Size ◽  
Solar Dryer ◽  
Curcuma Xanthorrhiza

Vitanti TAP, Kawiji, Edhi N. 2012. Effect of extraction method on Curcuma xanthorrhiza oleoresin using solar dryer to concentration of curcuminoid, total phenol, and antioxidant activity. Biofarmasi 14: 1-9. Curcuma (Curcuma xanthorrhiza Roxb.) is a type of drug plant that has high enough capacity of production in Indonesia. Generally, commerced in the form of fresh curcuma or processed product as simple as simplicia and curcuma powder. Processed products that could be developed is curcuma oleoresin. It is a mixture of essential oils and resins obtained from extraction process of curcuma powder using an organic solvent. Oleoresin has the same flavor and aroma to the extracted material. Due to these characteristics, it is used as a flavor and food coloring, other than as a raw material in pharmaceutical industry. In addition, it also contains active compounds which can support the utilization of drug and food industries. This study aims to determine whether the size of the powder, powdered curcuma immersion time, and interactions between them that can be influenced the content of curcuminoids, total phenol and antioxidant activity of curcuma oleoresin. Selection of solar dryers in the drying process is based on previously studied that compare the natural drying technique with a solar dryer, and the best results of those studies are shown in the solar dryer. This research using completely randomized design with two factors: the size variation of curcuma powder (60, 80 and 100 mesh) and immersion time variation (extraction) of curcuma powder (12, 24 and 36 hours). The results showed that the powder size of curcuma and immersion time has an effect on curcuminoid content, total phenol and antioxidant activity of curcuma oleoresin. However, there are no interaction between both factors. That is, the size and the immersion time of curcuma powder do not affect each other on the content of curcuminoid, total phenol and activity of antioxidant.

scholarly journals UJI AKTIVITAS ANTIOKSIDAN DAN PENENTUAN TOTAL KANDUNGAN FENOLIK EKSTRAK ETANOL DAUN NANAMUHA (Bridelia monoica Merr)

PHARMACON ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 178
Author(s):  
Julia Elsa Lakoro ◽  
Max R. J. Runtuwene ◽  
Paulina V. Y. Yamlean
Keyword(s):  
Antioxidant Activity ◽  
Extraction Method ◽  
Total Phenol ◽  
Total Phenolic ◽  
Total Phenol Content ◽  
Phenol Compounds ◽  
Activity Test ◽  
Ic50 Value ◽  
Dpph Method ◽  
Ethanol Extracts

ABSTRACTNanamuha (Bridelia monoica Merr.) is a plant that was used as a cancer and tumor drug by the Sangihe Islands community. This plant contains phenol compounds, flavonoids, alkaloids and tannins. The purpose of this study was to determine the potential of nanamuha leaves that grow in the Sangihe Island to have antioxidant activity and determine the total phenolic ethanol extracts of nanamuha leaf. The extraction method used is maceration with ethanol solvent p.a. The extracts obtained was determined total phenolic and antioxidant activity test using DPPH method. Based on the results obtained, the ethanol extracts of nanamuha leaves has antioxidant activity with an IC50 value of 75,03 µg / mL and the result showed that the total phenol content the ethanol extracts of nanamuha leaves of  53,34 mg / L.  Keywords : Nanamuha leaf, total phenol, antioxidant activity, DPPH  ABSTRAKNanamuha (Bridelia monoica Merr.) merupakan tanaman yang dimanfaatkan sebagai obat kanker dan tumor oleh masyarakat Kepulauan Sangihe. Tanaman ini memiliki kandungan senyawa fenol, flavonoid, alkaloid dan tanin. Tujuan dari penelitian ini adalah unutuk mengetahui potensi dari daun nanamuha yang tumbuh di Kepulaun Sangihe ini memiliki aktivitas antioksidan dan menentukan total fenolik dari ekstrak etanol daun nanamuha. Metode ekstraksi yang digunakan adalah maserasi dengan pelarut etanol p.a. Ekstrak yang diperoleh ditentukan total fenolik dan uji aktivitas antioksidan dengan metode DPPH. Berdasarkan hasil yang didapatkan ekstrak etanol daun nanamuha memiliki aktivitas antioksidan dengan nilai IC50 75,03 µg/mL dan hasil penelitian menunjukan total kandungan fenolik ekstrak etanol daun nanamuha sebesar 53,34 mg/L. Kata kunci : Daun Nanamuha, Total fenol, Aktivitas antioksidan, DPPH

scholarly journals Genotypic Variation of Total Phenol and Oleuropein Concentration and Antioxidant Activity of 11 Greek Olive Cultivars (Olea europaea L.)

HortScience ◽  
2012 ◽  
Vol 47 (3) ◽  
pp. 339-342 ◽  
Author(s):  
Antonios Petridis ◽  
Ioannis Therios ◽  
Georgios Samouris
Keyword(s):  
Antioxidant Activity ◽  
Industrial Production ◽  
Biochemical Composition ◽  
Olea Europaea ◽  
Genotypic Variation ◽  
Total Phenol ◽  
Raw Material ◽  
Measured Parameter ◽  
Olea Europaea L ◽  
Olive Cultivars

The chemical and biochemical composition of olives relies on some agronomical factors, one of which is the cultivar. In this study, fruits and leaves of 11 Greek olive cultivars were examined concerning their phenol and oleuropein concentrations. Fruit antioxidant activity was determined as well. The obtained results showed that significant differences existed among cultivars regardless of the tissue or the measured parameter. In general, leaves had higher total phenol and oleuropein concentrations than fruits. Finally, the highest oleuropein concentration in fruits was recorded in ‘Pikrolia Kerkiras’ followed by ‘Romeiki’, ‘Megaritiki’, ‘Kothreiki’, and ‘Kalamon’. These cultivars may constitute the raw material in the industrial production of oleuropein.

The Application Analysis of Crude Ricin in Terrorism

2012 ◽  
Vol 549 ◽  
pp. 1051-1054
Author(s):  
Xin Wang ◽  
Peng Peng ◽  
Shan Mao Li ◽  
Da Wei Jiang ◽  
Guo Hong Liu ◽  
...  
Keyword(s):  
Extraction Method ◽  
Extraction Process ◽  
Raw Material ◽  
Material Sources ◽  
Toxic Material ◽  
Application Analysis ◽  
Simple Extraction

Ricin is a highly toxic material, which can be extracted from semenricini. Due to the extensive raw material sources and the simple extraction process, it is very possible for ricin to become one of the attack means for terrorist. Therefore, it is necessary to make analysis of its extraction method, toxicity, and the corresponding routes for harm transmission.

Variation of the antioxidant activity with the extraction method and solvent selection

2020 ◽  
Vol 10 (4) ◽  
pp. 39-42
Author(s):  
Sravan Kumar P ◽  
Akila CR ◽  
Vinaya B ◽  
Dinesh Babu J
Keyword(s):  
Antioxidant Activity ◽  
Extraction Method ◽  
Chemical Constituents ◽  
Extraction Process ◽  
Vital Role ◽  
Distilled Water ◽  
Polar Solvents ◽  
Extraction Solvent ◽  
Significant Step ◽  
Guava Leaves

Extraction is a significant step in the processing of the crude drug to get its chemical constituents out and keep them of high and exportable quality. The plants have various chemical constituents that are responsible for various activities in which antioxidant activity is the important one. There is another step that is crucial in the extraction process that is the selection of the suitable for extraction. Various solvents are used for extraction. They too range from the highly non-polar solvents like benzene and chloroform to the highly polar solvents like Ethanol and distilled water. So, in this work, the focus has been put on to find the effect of the extraction method and the extraction solvent on the antioxidant profile of the guava leaves. The extracts of the solvent Water in the method of ultrasound showed the highest inhibition of the free radicals and the least was with the extracts of the pet ether and using soxhlation. This is indicative that the method of extraction is critical, and the solvent of extraction played a vital role in the content of chemical constituents and the pharmacological activity too. The results showed that the ultrasound method was beneficial in extracting the soft drugs like leaves, and the distilled water was effective in extracting the chemicals from the guava leaves.

scholarly journals The optimization of extraction process of white mulberry leaves and the characteristic bioactive properties its powder extract

2019 ◽  
Vol 65 (1) ◽  
pp. 12-19
Author(s):  
Krzysztof Przygoński ◽  
Elżbieta Wojtowicz
Keyword(s):  
Antioxidant Activity ◽  
Dry Matter ◽  
Extraction Process ◽  
Water Extraction ◽  
Raw Material ◽  
Mulberry Leaves ◽  
Mulberry Leaf ◽  
Bioactive Properties ◽  
White Mulberry ◽  
Powder Extract

Summary Introduction: Powder extracts from white mulberry leaves (Morus alba L.) are desirable due to their simplicity of use. Powders intended for use in food and dietary supplements can be obtained by various methods, including water extraction and spray drying. Objective: The aim of the work was to optimize the aqueous process of extraction of white mulberry leaves and characterization of bioactive properties of the obtained extract powder. Methods: The DNJ and flavonoids (quercetin, kaempferol) contents and were analysed by high performance liquid chromatography (HPLC). Total phenolic contents were determined using the Folin-Ciocalteu phenol reagent and antioxidant activity by ABTS and DPPH assays. Results: The mulberry leaf extraction process has been optimized. The obtained powdered mulberry leaf extract proved to be a good source of bioactive compounds. Characteristic phenolic compounds detected in mulberry leaves and their powder extract were quercetin and kaempferol. The sum of polyphenols was 10.9 mg GAE/g dry matter in the raw material, whereas in the powder extract 42.6 mg GAE/g dry matter. In addition, it was found that the obtained powdered extract is characterized by a five-fold higher, in comparison to the raw material, the content of antioxidant activity measured by ABTS and DPPH tests. The content of 1-deoxynojirimycin (DNJ) in the powder extract was nearly four times higher than in dry mulberry leaves. Conclusion: The optimized process of water extraction of white mulberry leaves allows to keep valuable bioactive components and to obtain their high concentration.

scholarly journals A green extraction design for enhancing flavonoid compounds from Ixora javanica flowers using a deep eutectic solvent

2020 ◽  
Vol 7 (10) ◽  
pp. 201116
Author(s):  
Nina Dewi Oktaviyanti ◽  
Kartini Kartini ◽  
Mochammad Arbi Hadiyat ◽  
Ellen Rachmawati ◽  
Andre Chandra Wijaya ◽  
...  
Keyword(s):  
Extraction Method ◽  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Extraction Process ◽  
Raw Material ◽  
Molar Ratio ◽  
Flavonoid Compound ◽  
Total Flavonoids ◽  
Green Extraction ◽  
Optimum Extraction

In this study, an environmentally friendly extraction method for flavonoid compound from Ixora javanica , as a new raw material candidate for herbal medicine and cosmetics, was developed. The objectives of the present work were to provide recommendations for the optimal extraction conditions and to investigate the effects of any extraction parameters on flavonoid yields from the I. javanica flower. The extraction process was performed using deep eutectic solvent (DES) (choline chloride and propylene glycol at molar ratio of 1 : 1) and the ultrasound-assisted extraction method. Both single-factor and response surface analyses using three-level and three-factor Box Behnken designs were conducted to obtain the optimum flavonoid concentrations. The results showed that the optimum extraction conditions for total flavonoids featured an extraction time of 40 min, 25% water content in DES and a solid-to-liquid ratio of 1 : 25 g ml −1 . An extract obtained under optimum extraction conditions showed higher total flavonoid yields than an ethanolic extract which was used for comparison. Scanning electron microscope images demonstrated that both of the solvents also showed different effects on the outer surface of the I. javanica flower during the extraction process. In summary, our work succeeded in determining the optimum conditions for total flavonoids in the I. javanica flower using a green extraction method.

scholarly journals Principal phenolic phytochemicals in French Syrah and Grenache Rhone wines and their antioxidant activity in inhibiting oxidation of human low density lipoproteins

OENO One ◽  
1995 ◽  
Vol 29 (4) ◽  
pp. 205 ◽  
Author(s):  
Pierre-Louis Teissedre ◽  
Andrew L. Waterhouse ◽  
Edwin N. Frankel
Keyword(s):  
Antioxidant Activity ◽  
Extraction Process ◽  
Low Density Lipoproteins ◽  
Total Phenol ◽  
Ldl Oxidation ◽  
Phenolic Antioxidants ◽  
Cabernet Sauvignon ◽  
Natural Plant ◽  
Phenolic Phytochemicals ◽  
Catalyzed Oxidation

<p style="text-align: justify;">Wine contains natural plant phenolic antioxidants that may protect circulating lipoproteins from oxidative damage. By inhibition of the copper-catalyzed oxidation of LDL we determined the activity of thirteen Rhône coast wines exclusively from Syrah and Grenache varieties. About 50 p. cent of the wines were made with a long maceration process. Major monomeric phenolic compounds and procyanidin dimers were analyzed in each sample by HPLC and correlated with relative LDL antioxidant activity. Correlations obtained can be grouped in 3 classes: catechin (r = 0.75), procyanidins, BI, B2, B3 (r = 0.43-0.55), malvidin-3-glucoside and cyanidin (r = 0.43), gallic acid, myreeitin, rutin (r = 0.2-0.4). On the same basis total phenol contents of wines gave a correlation with LDL antioxidant activity of r = 0.72. Comparison, at the same total phenol concentration, with different red California wines shows that antioxidant activity of French Syrah and Grenache range between that of Merlot (56-65 p. cent) and Cabernet Sauvignon (37-45 p.cent). In contrast Syrah wines made with a short extraction process gave lower inhibition of LDL oxidation of 16 p. cent which is less than white Califomia wines averaging 36 p. cent. Activity of each wine phenolic compound can play a role in protecting LDL against oxidation.</p>

scholarly journals Optimization of Enzymatic-assisted Extraction of Polysaccharides from Roxburgh Rose Pomace and its Antioxidant Activity

2019 ◽  
Vol 78 ◽  
pp. 02014 ◽  
Author(s):  
Xiaoli Zhou ◽  
Guangxu Zhu ◽  
Yansheng Yang ◽  
Bin Du ◽  
Dong Lin
Keyword(s):  
Antioxidant Activity ◽  
Optimal Condition ◽  
Orthogonal Experiment ◽  
Natural Antioxidants ◽  
Extraction Process ◽  
Enzyme Concentration ◽  
Raw Material ◽  
Pharmaceutical Industries ◽  
Solid Liquid

In this experiment, at first the roxburgh rose juice was extracted and then roxburgh rose residue was taken as raw material. We have used the enzyme assisted method to study the extraction process of polysaccharides from roxburgh rose pomace. The effects of mesh number, the concentration of the enzyme, temperature and time, pH and solid-liquid ratio on the polysaccharides yield were explored by single factor experiments. And then orthogonal experiment was designed to study the optimal techniques on extracting of polysaccharides from pomace. The in vitro antioxidant activity of the obtained polysaccharides was studied. The results showed that the optimal condition of extracting polysaccharides was as follows: enzyme concentration 2.5%, enzymatic hydrolysis at 60° for 40 min, pH 4.0, mesh number were 100 and solidliquid ratio was 1:25 based on the ratio of cellulase and pectinase was 2: 1. The average polysaccharides yield of enzymatic extraction method reached (4.79±0.07) % under the optimal condition. The antioxidant activity assays in vitro revealed that polysaccharides from roxburgh rose pomace can be used as natural antioxidants in functional foods and pharmaceutical industries.

scholarly journals Secondary resources of tomato processing as a valuable raw material for obtaining food ingredients

2021 ◽  
Vol 17 (2) ◽  
pp. 40-47
Author(s):  
E. V. Lisovaya ◽  
E. P. Victorova ◽  
A. V. Sverdlichenko ◽  
N. N. Kornen
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Properties ◽  
Extraction Process ◽  
Biologically Active ◽  
Raw Material ◽  
Food Ingredients ◽  
Tomato Pomace ◽  
Secondary Resources ◽  
Tomato Processing ◽  
Vegetables And Fruits

It is known that enterprises processing vegetables and fruits generate secondary resources (waste), in particular, pomace, in significant volumes. The most valuable, in terms of the composition and content of biologically active macro- and micronutrients, is tomato pomace. Tomato pomace is a valuable source of natural carotenoids, including lycopene, which exhibits high antioxidant activity. The article provides an overview of scientific research aimed at developing methods for extracting carotenoids, including lycopene, from recycled tomato processing resources. It has been shown that, in general, when extracting carotenoids, including lycopene, from secondary resources of tomato processing, various methods of drying and grinding the raw material are used, and then biologically active substances are extracted. It should be noted that the method of pretreatment of the feedstock, the nature of the solvent, the temperature and duration of the extraction process have a significant effect on the antioxidant activity and bioavailability of carotenoids obtained as a result of extraction. It is shown that the use of a pulsed electric field, treatment with enzymes and ultrasonic treatment of tomato pomace allow to intensify the process of extraction of carotenoids and maximally preserve their antioxidant properties. Thus, it can be concluded that tomato pomace is a valuable raw material for obtaining extracts of carotenoids and, first of all, lycopene, and the development of effec- tive modes of the extraction process that ensure the maximum manifestation of antioxidant properties and the bioavailability of the extracted substance is an urgent task.

scholarly journals Optimization of the extraction process of compounds with antioxidant activity of tommy atkins mango peel

2020 ◽  
Vol 9 (10) ◽  
pp. e9939109273
Author(s):  
Felipe da Silva Veloso ◽  
Eliane Colla ◽  
Aziza Kamal Genena
Keyword(s):  
Antioxidant Activity ◽  
Extraction Process ◽  
Fractional Factorial ◽  
Raw Material ◽  
Extraction Time ◽  
Antioxidant Compounds ◽  
Solvent Ratio ◽  
Solution Ph ◽  
Maximum Extraction ◽  
Mango Peel

It is well known that vegetable residues from the food industry can be used as a possible source for the extraction of compounds with antioxidant activity; in the case of mango, approximately 40 to 60% of the total mass of the fruit is considered as residue after processing. This work focused on the optimization of the extraction process of compounds with antioxidant activity from the rind of Tommy Atkins mango. Initially a Fractional Factorial Design 25-1 (FFD) was applied to study the effect of five variables on the extraction process, namely: extraction time (min), percentage of ethanol in aqueous solution (%), pH, dry/solvent mango peel ratio (g/mL) and ultrasound power range (%). The variables extraction time and dry/solvent mango peel ratio were selected, which were evaluated sequentially by the application of a Central Composite Rotatable Design (CCRD) to determine the conditions of maximum extraction of antioxidant compounds by the response surface analysis. The ABTS•+ and Folin-Ciocalteu methods were used for the quantification of the antioxidant activity.  The maximum extraction occurred with the use of water, extraction time of 30 min, dry mango peel/solvent ratio of g/mL (1:100), at natural pH of the mixture (pH 4.6 ± 0.20) and sonication amplitude at 50%. It was possible to develop an extraction process of compounds with antioxidant activity from the mango peel, in order to maximize yield through the use of non-toxic solvents and using an agro-industrial residue as raw material.

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