scholarly journals Leprosy in children in Cuba: Epidemiological and clinical description of 50 cases from 2012–2019

2021 ◽  
Vol 15 (10) ◽  
pp. e0009910
Author(s):  
Raisa Rumbaut Castillo ◽  
Laura C. Hurtado Gascón ◽  
Jenny Laura Ruiz-Fuentes ◽  
Fernanda M. Pastrana Fundora ◽  
César R. Ramírez Albajés ◽  
...  
Keyword(s):  
Active Surveillance ◽  
Age Groups ◽  
Control Program ◽  
World Health ◽  
Household Transmission ◽  
Contact Investigation ◽  
Operational Classification ◽  
Mode Of Detection ◽  
History Of ◽  
Clinical Description

Introduction In 1993, Cuba achieved leprosy elimination according to the World Health Organization’s (WHO) indicator of less than one case per 10,000 population. Despite this achievement, detection of new cases occurs every year among all age groups including children. Detection of new cases in children reveals persistent transmission of the infection. Objective To describe the clinical and epidemiological features of leprosy in individuals younger than 15 years (childhood leprosy) reported to the Cuban National Leprosy Control Program (NLCP) between 2012 and 2019. Methods We conducted a retrospective descriptive study between 2012 and 2019 to assess the clinical and epidemiologic features of individuals under the age of 15 years with a confirmed diagnosis of leprosy reported to the NLCP. We reviewed the NLCP database and collected data to better define the total number of cases of leprosy in adults, children (younger than 15 years). We assessed socio-demographic variables (age, gender, and province of residence) as well as variables of clinical interest including operational classification and staging at diagnosis, bacillary index, grade of disability by WHO staging. Additionally, we evaluated epidemiological variables including passive versus active surveillance of cases, contact investigation focusing specifically in household transmission, and the degree of kinship as well as standing of the child within the focus of transmission when there were additional cases. Results We identified fifty children during the study period corresponding to 3% of the overall cases of leprosy comprising all age groups in Cuba. In the age group younger than 15 years, the majorities of cases was from the Granma province and most were between the ages of 10 and 14 years. Clinically, multibacillary/lepromatous forms were the most common type identified with positive bacillary index. The majority of children diagnosed with leprosy during our study period had a history of a relative with a confirmed diagnosis of leprosy. Conclusions Detection of cases of leprosy in individuals younger than 15 years of age in Cuba demonstrates ongoing transmission of M. leprae in specific geographic hotspots. Its frequency in the early adolescence, the predominant clinical forms, and the mode of detection associated with sources of suspected familiar infection demonstrated that there is a need for further efforts by the NLCP to conduct active surveillance activities among affected communities to identify cases of leprosy earlier with the goal of preventing further household and community transmission.

scholarly journals Ten years tuberculosis trend in Gambella Regional Hospital, South Western Ethiopia

2014 ◽  
Vol 1 (1) ◽  
pp. 18-24 ◽  
Author(s):  
Getahun Asebe ◽  
Gobena Ameni ◽  
Ketema Tafess
Keyword(s):  
Age Groups ◽  
Control Program ◽  
Regional Hospital ◽  
World Health ◽  
Notification Rate ◽  
Major Health ◽  
Pulmonary Tb ◽  
The Status ◽  
Health Organization ◽  
Western Ethiopia

Background: Tuberculosis (TB) is a chronic infectious disease mainly caused by Mycobacterium tuberculosis (MTBC). It is one of the major health problems in Ethiopia, across the nation. According to World Health Organization 2009 report the status of TB in Gambella Region was the highest from all the Ethiopian Regions, with the notification rate of (new and relapse) 261-421/100, 000. We, therefore, carried out this study to investigate the trend of TB in Gambella Regional Hospital Southwest Ethiopia. Methods: The study was conducted at the Gambella Regional Hospital, South Western Ethiopia. Retrospectively the medical records of all TB patients registered from 1st January 2003 to 14th November 2012 were assessed. Results: The results of the study revealed that there were 4300 TB cases registered in the ten years duration in Gambella Regional Hospital. Males consist the highest percentage 2430 (56.51%). Out of 4300 TB cases registered 1045 (24.30%) had Extra pulmonary TB (EPTB) and 3255 (75.70%) suffered from pulmonary TB (PTB) (χ2=31. 14; p<0.001). From 3255 registered PTB cases, smear positive PTB accounted for 1368 (31.81%) of the cases. The age groups 15-44took the highest percentage among the patients 2918 (67.86%). Only 1444 patients were knew their HIV status out of these 423 (29.29%) were HIV positives. The trend in TB registered cases of all forms of TB was gradually declining in the ten years. Conclusion: The retrospective study showed that TB problem in the study area was not at the level to be undermined. Hence, TB control program should give attention to the control of TB in Gambella Region.  

scholarly journals ACTIVE SURVEILLANCE OF THE SPUTNIK V VACCINE IN HEALTH WORKERS

2021 ◽  
Author(s):  
Vanina Pagotto ◽  
Analia Ferloni ◽  
María Mercedes Soriano ◽  
Morena Díaz ◽  
Manuel Braguisnky Golde ◽  
...  
Keyword(s):  
Active Surveillance ◽  
Health Professionals ◽  
Cox Regression ◽  
Health Workers ◽  
Age Groups ◽  
Self Report ◽  
World Health ◽  
Serious Adverse Events ◽  
Systemic Reactions ◽  
Medical Evaluation

AbstractIntroductionThe World Health Organization (WHO) recommends vaccination against Sars Cov-2 coronavirus to mitigate COVID-19 pandemic. On December 29th, the Argentine Ministry of Health started a vaccination plan with the Sputnik V vaccine emphasizing the registration of the Events Supposedly Attributed to Vaccines and Immunizations (ESAVI) in the National Surveillance System. The aim of this study is to determine the safety of this vaccine.MethodsIn an ongoing cohort study, health professionals from Hospital Italiano de Buenos Aires vaccinated with the first component of the Sputnik V vaccine (a rAd26 vector-based) were followed up. Safety at 72 hs was analysed from a self-report form. Local and systemic reactions were characterized as mild, moderate and severe. Incident rates were calculated per 1000 person-hours by age groups and gender. Adjusted hazard ratio and 95% Confidence Interval (HR; 95%CI) is obtained by Cox Regression Model.Results707 health professionals (mean age 35, 67% female) were vaccinated, response rate was 96,6% and 71,3% reported at least one ESAVI. Rate was 6.3 per 1.000 person-hours. Among local reactions, 54% reported pain at the injection site, 11% redness and swelling. Among systemic reactions 40% reported fever, 5% diarrhea and 68% new or worsened muscle pain. Five percent had serious adverse events that required medical evaluation and one inpatient.ESAVI rate was higher among females (65.4% vs 50%; HR 1.38, 95%CI 1.13-5.38) and in younger than 55 years-old (72.8% vs 32%; HR 2.66, 95%CI 1.32-1.68).ConclusionActive surveillance on safety for vaccines with emergency approval is mandatory. This study shows high rates of local and systemic reactions however early serious events were rare. Short term safety is supported by these preliminary findings. Studies on long term safety and efficacy, accoding sex and age, are needed.

scholarly journals Suicide, A Public Health Problem in Brazil

2021 ◽  
Author(s):  
Maria Cecília de Souza Minayo ◽  
Camila Alves Bahia
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Mortality Rate ◽  
Health Problem ◽  
Age Groups ◽  
Public Health Problem ◽  
Incidence Rates ◽  
World Health ◽  
History Of ◽  
Health Organization

This text focuses on the situation of suicide in Brazil, defines and quantifies information, and presents a description of the main risk factors, as well as a reflection on the phenomenon and the possibilities for prevention. Fatal suicide is a serious public health problem. In 2012, 172 member states of the World Health Organization registered 804,000 self-inflicted deaths, representing an annual rate of 11.4/100,000, of which 15/100,000 men and 8.0/100,000 women. Consummate suicide rates are unevenly distributed globally, within countries, according to sex and according to age groups. The mortality rate is highest in Asia (17.7/100 thousand inhabitants), followed in Europe (12/100 thousand inhabitants). The Americas have a mortality rate of 7.3/100 thousand inhabitants (WHO, 2014). In Brazil, with an unevenly distributions between the regions, gender and ages, the total rate is 4.5/100,000. In the country and everywhere, risk factors are classified as medical, psychiatric and psychological, micro social, social and environmental. The history of the occurrence of suicides shows that it is possible to prevent them and to reduce the incidence rates. This requires investment in local diagnostics and multidisciplinary action. Given the delicacy of the problem and the taboos that surround it, the protection network for people at risk for suicide needs to be constantly in the process of training and taking action. As national and international surveys show, at least two-thirds of the individuals who tried or committed suicide had somehow communicated to friends, family, acquaintances or health professionals their intention to kill themselves.

scholarly journals Factors Related To Anxy Events In Diabetes Mellitus Type 2 In Public Health Center

2020 ◽  
Vol 4 (3) ◽  
pp. 149-158
Author(s):  
Ira Inayah ◽  
Aszrul AB ◽  
Edison Siringoringo ◽  
Nurlina
Keyword(s):  
Public Health ◽  
Pulmonary Tuberculosis ◽  
Health Center ◽  
Age Groups ◽  
Case Control ◽  
World Health ◽  
P Value ◽  
Control Approach ◽  
History Of ◽  
Health Organization

Tuberculosis is a contagious disease caused by the bacteria Mycobacterium Tuberculosis which is spread through droplets of people who have been infected with tuberculosis bacilli. Pulmonary tuberculosis is still a challenge in public health problems both regionally, nationally, and globally. According to the World Health Organization (WHO) in 2015, there were 10.4 million new TB cases and nearly 75% of pulmonary tuberculosis patients were economically productive age groups. . The purpose of this study was to determine the physical environmental factors of the house with the incidence of pulmonary tuberculosis at the Bonto Bahari Health Center in 2020. The research method used was using analytical research methods with a case-control approach (case-control) where subjects, namely cases and controls were known and selected based on the output ( out came), then looked back (backward) about the history of the research exposure status experienced by the subject. The population in this study was about 40 people and the sample in this study amounted to 80 because the researcher took 40 controls. The results of the analysis using the Wilcoxon and Mc Nemar tests, with the results obtained by the value of ventilation (p-value = 0.001) then Ho is rejected and Ha is accepted. The type of floor obtained value (p-value = 1,000) then Ho is accepted and Ha is rejected. The type of wall obtained value (p-value = 0.002) then Ho is rejected and Ha is accepted. Occupancy density obtained value (p-value = 0.582) then Ho is accepted and Ha is rejected. The conclusion of this study There is a relationship between ventilation and the incidence of pulmonary tuberculosis, there is a relationship between the type of wall and the incidence of pulmonary tuberculosis and there is no relationship between floor type and occupancy density with the incidence of pulmonary tuberculosis.

scholarly journals Physical Environment Factors With Events Of Home Lung Tuberculosis In Public Health Bonto Bahari

2020 ◽  
Vol 4 (3) ◽  
pp. 116-129
Author(s):  
Arum Dani ◽  
Andi Suswani ◽  
Asri
Keyword(s):  
Public Health ◽  
Pulmonary Tuberculosis ◽  
Age Groups ◽  
Case Control ◽  
World Health ◽  
P Value ◽  
Control Approach ◽  
Lung Tuberculosis ◽  
History Of ◽  
Health Organization

Tuberculosis is a contagious disease caused by the bacteria Mycobacterium Tuberculosis which is spread through droplets of people who have been infected with tuberculosis bacilli. Pulmonary tuberculosis is still a challenge in public health problems both regionally, nationally, and globally. According to the World Health Organization (WHO) in 2015, there were 10.4 million new TB cases and nearly 75% of pulmonary tuberculosis patients were economically productive age groups. . The purpose of this study was to determine the physical environmental factors of the house with the incidence of pulmonary tuberculosis at the Bonto Bahari Health Center in 2020. The research method used was using analytical research methods with a case-control approach (case-control) where subjects, namely cases and controls were known and selected based on the output ( out came), then looked back (backward) about the history of the research exposure status experienced by the subject. The population in this study was about 40 people and the sample in this study amounted to 80 because the researcher took 40 controls. The results of the analysis using the Wilcoxon and Mc Nemar tests, with the results obtained by the value of ventilation (p-value = 0.001) then Ho is rejected and Ha is accepted. The type of floor obtained value (p-value = 1,000) then Ho is accepted and Ha is rejected. The type of wall obtained value (p-value = 0.002) then Ho is rejected and Ha is accepted. Occupancy density obtained value (p-value = 0.582) then Ho is accepted and Ha is rejected. The conclusion of this study There is a relationship between ventilation and the incidence of pulmonary tuberculosis, there is a relationship between the type of wall and the incidence of pulmonary tuberculosis and there is no relationship between floor type and occupancy density with the incidence of pulmonary tuberculosis.

scholarly journals Household transmission of acute gastroenteritis during the winter season in Japan

2018 ◽  
Vol 46 (7) ◽  
pp. 2866-2874 ◽  
Author(s):  
Ryota Matsuyama ◽  
Fuminari Miura ◽  
Shinya Tsuzuki ◽  
Hiroshi Nishiura
Keyword(s):  
Acute Gastroenteritis ◽  
Close Contact ◽  
Age Groups ◽  
Winter Season ◽  
Household Survey ◽  
Epidemiological Analysis ◽  
Household Transmission ◽  
Social Settings ◽  
Age Dependent ◽  
History Of

Objectives Acute gastroenteritis, including illness caused by norovirus, is sometimes transmissible among susceptible persons who experience close contact, including those within a household, and it disturbs social activities of patients and their family. However, epidemiological assessment of the transmissibility and its heterogeneity has not been conducted. The present study aimed to quantify the frequency of household transmission that was likely caused by norovirus, and characterize its determinants. Methods A household survey was conducted, analyzing the history of suspected norovirus infection from January to March, 2017. Noro-like illness was clinically defined as a patient with either: (i) diarrhea or vomiting multiple times a day; or (ii) diarrhea or vomiting persisting for 2 or more days. Results Among 380 households, 132 households (34.7%) were eligible for epidemiological analysis, with an estimated secondary attack risk of 13.8% (38/276). Age-specific secondary attack risk was highest among index case patients aged 0 to 14 years (25.8%). The prevalence of vomiting in this age group was higher than in other age groups, with an odds ratio of household transmission estimated at 4.3. Conclusions Age-dependent heterogeneity was successfully identified, offering critical insights into future considerations for norovirus control at various social settings.

Organization of restrictive quarantine measures to prevent especially dangerous infections

2020 ◽  
pp. 6-11
Author(s):  
Petr Ilyin
Keyword(s):  
Infectious Diseases ◽  
Clinical Symptoms ◽  
International Health ◽  
World Health ◽  
The World ◽  
History Of ◽  
Entire History ◽  
Health Organization ◽  
Former Ussr ◽  
Health Regulations

Especially dangerous infections (EDIs) belong to the conditionally labelled group of infectious diseases that pose an exceptional epidemic threat. They are highly contagious, rapidly spreading and capable of affecting wide sections of the population in the shortest possible time, they are characterized by the severity of clinical symptoms and high mortality rates. At the present stage, the term "especially dangerous infections" is used only in the territory of the countries of the former USSR, all over the world this concept is defined as "infectious diseases that pose an extreme threat to public health on an international scale." Over the entire history of human development, more people have died as a result of epidemics and pandemics than in all wars combined. The list of especially dangerous infections and measures to prevent their spread were fixed in the International Health Regulations (IHR), adopted at the 22nd session of the WHO's World Health Assembly on July 26, 1969. In 1970, at the 23rd session of the WHO's Assembly, typhus and relapsing fever were excluded from the list of quarantine infections. As amended in 1981, the list included only three diseases represented by plague, cholera and anthrax. However, now annual additions of new infections endemic to different parts of the earth to this list take place. To date, the World Health Organization (WHO) has already included more than 100 diseases in the list of especially dangerous infections.

Gambaran Pengetahuan Remaja Tentang Ca Serviks Dan Perilaku Pencegahan Ca Serviks Di Sma Negeri Tebing Tinggi Empat Lawang Tahun 2016

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Yuni Kurniati Yuni Kurniati
Keyword(s):  
Cervical Cancer ◽  
World Health Organization ◽  
Cancer Incidence ◽  
World Health ◽  
Cervical Cancer Incidence ◽  
Cross Sectional ◽  
History Of ◽  
Unhealthy Diet ◽  
Birth Control Pills ◽  
Health Organization

ABSTRACT   According to the World Health Organization (WHO), every two minutes a woman dies of cervical cancer in develoving countries. In Indonesia, new cases of cervical cancer is 40-45 cases of day. It is estimated every hour, a women died of cervical center. At the general hospital center Dr. Mohammad Hoesin Palembang, the incidence of women who had cervical cancer incidence year 2011 women who had cervical cancer incidence are 34 people (48,2%). The following factors increase the chance of cervical cancer in women is infection of Human Papilloma Virus (HPV), sexsual behavior, family history of cervical cancer, age, mechanism of how oral contraceptives, smoking, income or socioeconomic status, race , unhealthy diet, the cell abnormal, parity, use of the drug DES (Dietilsbestrol), and birth control pills. The purpose of this study is known of adolescents about cervical cancer in SMA Tebing Tinggi Empat Lawang year 2016. This study used Analytic Survey with Cross Sectional approach. The population in this study were all young women students in SMA Tebing Tinggi Empat Lawang with the number of 171 respondents. The results showed there were 171 respondents (37.5%) of respondents were knowledgeable, and (62.52%) of respondents who are knowledgeable unfavorable. These results indicate that knowledgeable either less than those less knowledgeable in both the SMA Tebing Tinggi Empat Lawang Year 2016. From these results, it is expected that more teens can know about cervical cancer so that it can add a lot of insight and knowledge.     ABSTRAK   Menurut data World Health Organization (WHO), setiap dua menit wanita meninggal dunia karena kanker serviks dinegara berkembang. Di Indonesia, kasus baru kanker serviks 40-45 kasus perhari. Di perkirakan setiap satu jam, seorang perempuan meninggal dunia karena kanker serviks. Di rumah sakit umum pusat Dr. Mohammad Hoesin Palembang, angka kejadian ibu yang mengalami kanker serviks pada tahun 2011 ibu yang mengalami kejadian kanker serviks terdapat 34 orang (48,2%). Faktor-faktor berikut meningkat kan peluang kanker serviks pada wanita yaitu infeksi Human Papiloma virus (HPV), perilaku seks, riwayat keluarga kanker serviks, umur ,mekanisme bagaimana kontrasepsi peroral, merokok, pendapatan atau status social ekonomi, ras, diet tidak sehat, adanya sel abnormal, paritas, menggunakan obat DES (Dietilsbestrol),dan pil KB. Tujuan penelitian ini adalah Diketahuinya pengetahuan remaja tentang Ca Cerviks di SMA Negeri Tebing Tinggi Empat Lawang Tahun 2016. Penelitian ini menggunakan metode survey  analitik dengan pendekatan cross sectional. Populasi pada penelitian ini adalah semua siswi remaja putri di SMA Negeri Tebing Tinggi Empat Lawang dengan jumlah 171 responden.Hasil penelitian menunjukkan dari 171 responden terdapat(37.5 %) responden yang berpengetahuan baik, dan (62.52  %) responden yang berpengetahuan kurang baik. Hasil penelitian ini menunjukan bahwa yang berpengetahuan baik lebih sedikit dibandingkan dengan  yang berpengetahuan kurang baik di SMA Negeri Tebing Tinggi Empat Lawang Tahun 2016. Dari hasil penelitian ini, Diharapkan remaja bisa lebih banyak mengetahui tentang caserviks sehingga dapat menambah banyak wawasan dan pengetahuan.    

A new medical Internet system in healthcare: innovation of Telegeriatrics and healthcare demands of older patients of different age groups (Preprint)

2020 ◽  
Author(s):  
Yu Gong ◽  
Jianyuan Zhou
Keyword(s):  
Cardiovascular Diseases ◽  
General Practitioners ◽  
Older Patients ◽  
Metabolic Diseases ◽  
Treatment Plan ◽  
Age Groups ◽  
The Elderly ◽  
Diagnosis And Treatment ◽  
World Health ◽  
New Model

BACKGROUND Healthcare for older patients is a worldwide challenge for public health system. A new medical Internet system in healthcare which is a new model of telegeriatrics system has been established. The key innovation is the new telegeriatrics system was conducted jointly by general practitioners in the Community Health Service Center and specialists in university teaching hospital. Unlike the typical telemedicine that has been practiced in other countries, the new model provides a solution for the key issues in telemedicine where a doctor is unable to conduct a direct physical examination and the associated potential diagnostic error. OBJECTIVE This study is to introduce the operation mechanism of the new Telegeriatrics system and analyze healthcare demands of older patients in different age groups applying the new Telegeriatrics system. METHODS 472 older patients (aged≥60) were enrolled and divided into the young older group (aged 60 to 74), the old older group (aged 75 to 89) and the very old group (aged≥90) according to the age stratification of World Health Organization. Proportion of the top 10 diseases of older patients of different age groups was analyzed. RESULTS The process of older patients’ diagnosis and treatment made by specialist and general practitioners formed a closed loop. It ensures the timeliness and effectiveness of diagnosis and treatment of older patients. The treatment effect can be observed by general practitioners and specialist can adjust the treatment plan in time. In this study, it was found that older patients in different age groups have different healthcare demands. Coronary heart disease and type 2 diabetes mellitus were found to be the main diseases of the older patients and the young older patients as well as the old older patients applying Telegeriatrics. CONCLUSIONS The new telegeriatrics system can provide convenient and efficient healthcare services for older patients and overcome the disadvantage of currently used models of telegeriatrics. Older patients in different age groups have different medical care demands. Cardiovascular diseases and metabolic diseases have become the main diseases of the elderly applying the new Telegeriatrics system. Healthcare policy makers should invest more medical resources to the prevention of cardiovascular diseases and metabolic diseases in the elderly.

scholarly journals Predicting COVID-19 mortality with electronic medical records

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Hossein Estiri ◽  
Zachary H. Strasser ◽  
Jeffy G. Klann ◽  
Pourandokht Naseri ◽  
Kavishwar B. Wagholikar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medical Information ◽  
Age Groups ◽  
Prognostic Models ◽  
Smoking History ◽  
Risk Scores ◽  
Gradient Boosting ◽  
Chronic Obstructive ◽  
Clinical Expertise ◽  
History Of

AbstractThis study aims to predict death after COVID-19 using only the past medical information routinely collected in electronic health records (EHRs) and to understand the differences in risk factors across age groups. Combining computational methods and clinical expertise, we curated clusters that represent 46 clinical conditions as potential risk factors for death after a COVID-19 infection. We trained age-stratified generalized linear models (GLMs) with component-wise gradient boosting to predict the probability of death based on what we know from the patients before they contracted the virus. Despite only relying on previously documented demographics and comorbidities, our models demonstrated similar performance to other prognostic models that require an assortment of symptoms, laboratory values, and images at the time of diagnosis or during the course of the illness. In general, we found age as the most important predictor of mortality in COVID-19 patients. A history of pneumonia, which is rarely asked in typical epidemiology studies, was one of the most important risk factors for predicting COVID-19 mortality. A history of diabetes with complications and cancer (breast and prostate) were notable risk factors for patients between the ages of 45 and 65 years. In patients aged 65–85 years, diseases that affect the pulmonary system, including interstitial lung disease, chronic obstructive pulmonary disease, lung cancer, and a smoking history, were important for predicting mortality. The ability to compute precise individual-level risk scores exclusively based on the EHR is crucial for effectively allocating and distributing resources, such as prioritizing vaccination among the general population.

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