scholarly journals Birthweight Discordance, Risk Factors and its Impact on Perinatal Mortality Among Japanese Twins: Data From a National Project During 2001–2005

2010 ◽  
Vol 13 (5) ◽  
pp. 490-494 ◽  
Author(s):  
Ruoyan Gai Tobe ◽  
Rintaro Mori ◽  
Norio Shinozuka ◽  
Takahiko Kubo ◽  
Kazuo Itabashi

Our aims were to assess the incidence of birthweight discordance of twins, to explore risk factors and its impact on perinatal mortality, and to quantify the risks at different severity of birthweight discordance in Japan, by using a nationwide obstetric database. There were 10,828 pairs of twins, born from 2001 to 2005 recorded in the database of the national Perinatal Health Care Project, fully enrolled. The overall incidence of birthweight discordance was 47.34%. The incidence of mild, severe and extremely severe discordance was 19.26%, 10.21% and 17.87%, respectively. The incidence of birthweight discordance in Japan is much higher than that in other countries, particularly at higher severity level. By linear regression model, our study added independent factors of primiparity (p < .001), sex composition (p < .001), chorionicity (p < .001), gestational age (p < .001), and delivery mode (p < .001) in determining birthweight discordance percentage. Maternal age and application of assisted reproduction technologies (ART) didn't significantly influence the birthweight discordance. The birthweight discordance is closely associated with gestational age and affected discharge mortality. From 25% of birthweight discordance, risk to discharge mortality tended to significantly increase, suggesting it should be added as a reference for clinical practices.

2021 ◽  
pp. 1-3
Author(s):  
H. Anitha Virgin Kumari ◽  
S. Nivedita ◽  
M. Monisha

BACKGROUND Placenta previa describes a placenta that is implanted somewhere in the lower uterine segment,either over or near the internal cervical os. AIM OF THE STUDY To analyse the risk factors and outcomes associated with placenta previa METHODS A prospective study of all the placenta previa patients delivered at Govt RSRM Lying in Hospital,Chennai from June 2019 to November 2020 are included.Control of 533 patients without placenta previa were selected randomly during the same period.The differences between the groups with respect to age,parity ,mal presentation,pregnancy associated complications,gestational age at onset of bleeding,gestational age at delivery,mode of delivery,third stage complications,neonatal outcome,during of hospital stay are noted. RESULTS The risk of occurrence of placenta previa is increased with advancing maternal age,parity and previous uterine surgery.Incidence is 0.5%,69% of placenta previa cases delivered by cesarean section,10% developed PPH,2% managed surgically,25% preterm delivery. CONCLUSION Accurate diagnosis,judicious expectant management with blood transfusion as required and timely delivery may lead to the most favorable outcome. The current study also suggested that advancing maternal age,parity and cesarean section increase the risk of placenta previa.


2021 ◽  
Author(s):  
Nadia S. Eugster ◽  
Florence Corminboeuf ◽  
Gilbert Koch ◽  
Julia E. Vogt ◽  
Thomas Sutter ◽  
...  

Abstract Background Preterm neonates frequently experience hypernatremia (plasma sodium concentrations >145 mmol/l), which is associated with clinical complications, such as intraventricular hemorrhage. Study design In this single center retrospective observational study, the following 7 risk factors for hypernatremia were analyzed in very low gestational age (VLGA, below 32 weeks) neonates: gestational age (GA), delivery mode (DM; vaginal or caesarian section), sex, birth weight, small for GA, multiple birth, and antenatal corticosteroids. Machine learning (ML) approaches were applied to obtain probabilities for hypernatremia. Results 824 VLGA neonates were included (median GA 29.4 weeks, median birth weight 1170 g, caesarean section 83%). 38% of neonates experienced hypernatremia. Maximal sodium concentration of 144 mmol/l (interquartile range 142–147) was observed 52 hours (41–65) after birth. ML identified vaginal delivery and GA as key risk factors for hypernatremia. The risk of hypernatremia increased with lower GA from 22% for GA ≥ 31–32 weeks to 46% for GA < 31 weeks and 60% for GA < 27 weeks. A linear relationship between maximal sodium concentrations and GA was found, showing decreases of 0.29 mmol/l per increasing week GA in neonates with vaginal delivery and 0.49 mmol/l/week after cesarean section. Sex, multiple birth and antenatal corticosteroids were not associated hypernatremia. Conclusion VLGA neonates with vaginal delivery and low GA have the highest risk for hypernatremia. Early identification of neonates at risk and early intervention may prevent extreme sodium excursions and associated clinical complications.


2017 ◽  
Vol 24 (3) ◽  
pp. 105
Author(s):  
Yulisa Haslinda ◽  
Budi Prasetyo

Objectives: to determine the frequency distribution of perinatal mortality and maternal characteristic features in terms of age, parity, gestational age and pregnancy complications in Dr.Soetomo Hospital Surabaya in 2015. Materials and Methods: A descriptive study conducted by collecting data on patients who experienced perinatal mortality of infants born from January to December 2015 in Dr. Soetomo, Hospital Surabaya. Samples were collected using total sampling. The samples must meet the following criteria: mothers of infants with perinatal mortality in Dr. Soetomo Hospital, Surabaya, from January to December 2015.Results: There were 206 perinatal deaths out of 1018 births in Dr. Soetomo during 2015, of which 58% was live birth and 42% was stillbirth. Most of perinatal mortality found in the preterm gestational age as much as 78%, and gestational age 28-<37 weeks (58%). Most of perinatal mortality occured in infants with less than 1500 grams birth weight, which was as much as 53% of all perinatal deaths and infant whose birth weight from1500 to 2500 grams was about 29%. Most perinatal mortality found in multigravida (54%) and in infants whose mothers experienced preeclampsia in pregnancy complications (35%), followed by infant mortality in women with non-obstetric complications (23%).Conclusion: Perinatal mortality in Dr. Soetomo Hospital was mostly found in multigravida mothers, 16-35 years old maternal age, 28-37 weeks gestational age and those with complications of preeclampsia.


1998 ◽  
Vol 32 (3) ◽  
pp. 209-216 ◽  
Author(s):  
Ana M. B. Menezes ◽  
Fernando C. Barros ◽  
Cesar G. Victora ◽  
Elaine Tomasi ◽  
Ricardo Halpern ◽  
...  

INTRODUCTION: Although there was a considerable reduction in infant mortality in Pelotas, Rio Grande do Sul in the last decade, its perinatal causes were reduced only by 28%. The associated factors of these causes were analised. MATERIAL AND METHOD: All hospital births and perinatal deaths were assessed by daily visits to all the maternity hospitals in the city, throughout 1993 and including the first week of 1994. RESULTS: The perinatal mortality rate was 22.1 per thousand births. The multivariate analysis showed the following risk factors: low socioeconomic level, male sex and maternal age above 35 years . Among multigravidae women, the fetal mortality rate was significantly increased for mothers with a previously low birthweight and a previous stillbirth. For early neonatal mortality the risk was significantly increased by a smaller number of antenatal visits than 5 and low birthweight. CONCLUSIONS: Main risk factors for perinatal mortality: low socioeconomic level, maternal age above 35 years and male sex. For early neonatal mortality the risk was significantly increased by a smaller number of antenatal visits than 5 and low birthweight.


2021 ◽  
Vol 4 (1) ◽  
pp. 73
Author(s):  
Jianti Fina Lestari ◽  
Risa Etika ◽  
Pudji Lestari

Abstract Background: Low Birth Weight Babies (LBW) accounts for 60 - 80% of all neonatal deaths in the world. Not the only major predictor of mortality and morbidity in neonates, individuals with a history of LBW have a greater risk of experiencing various diseases such as hypertension, heart disease, and diabetes later in life. This systematic review study aims to identify maternal risk factors that contributing to LBW Method: Articles published between 2015 - 2020 in the Science Direct, Scopus and Cochrane library databases are systematically reviewed. Eleven articles that met the inclusion and exclusion criteria were included as samples for further review. Results regarding maternal risk factors for LBW events are synthesized systematically .Results: From the search results, there were 818 articles, after the screening process, the final results were 11 articles. Risk factors that are significantly related to LBW incidence in the article, are grouped in the subtheme, include: maternal age (<20 years, and each increase in age), parity (primipara and grandemultipara), low maternal upper arm circumference, hemoglobin levels less than 11 gr / dl, gestational age below 37 weeks, and complications during pregnancy. Conclusion: maternal age, parity, arm circumference, hemoglobin level, gestational age, and complications during pregnancy were significaly found to be maternal risk factors for LBW. 


Author(s):  
Carmen Ballesteros-Meseguer ◽  
César Carrillo-García ◽  
Mariano Meseguer-de-Pedro ◽  
Manuel Canteras-Jordana ◽  
Mª Emilia Martínez-Roche

Objective: to understand the episiotomy rate and its relationship with various clinical variables. Method: a descriptive, cross-sectional, analytic study of 12,093 births in a tertiary hospital. Variables: Parity, gestational age, start of labor, use of epidural analgesia, oxytocin usage, position during fetal explusion, weight of neonate, and completion of birth. The analysis was performed with SPSS 19.0. Results: the global percentage of episiotomies was 50%. The clinical variables that presented a significant association were primiparity (RR=2.98), gestational age >41 weeks (RR=1.2), augmented or induced labor (RR=1.33), epidural analgesia use (RR=1,95), oxytocin use (RR=1.58), lithotomy position during fetal expulsion (RR=6.4), and instrumentation (RR=1.84). Furthermore, maternal age ≥35 years (RR=0.85) and neonatal weight <2500 g (RR=0.8) were associated with a lower incidence of episiotomy. Conclusions: episiotomy is dependent on obstetric interventions performed during labor. If we wish to reduce the episiotomy rate, it will be necessary to bear in mind these risk factors when establishing policies for reducing this procedure.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Atsuro Uchida ◽  
Masayuki Miwa ◽  
Hajime Shinoda ◽  
Takashi Koto ◽  
Norihiro Nagai ◽  
...  

Aim. To find predictive and indicative markers of risk for development of retinopathy of prematurity (ROP) and its progression to the stage requiring laser treatment, in premature infants whose gestational age (GA) was under 33 weeks.Methods. We retrospectively reviewed medical records of 197 premature infants born in 2005–2010 whoseGA<33weeks and underwent eye screening at Keio University Hospital. The association between candidate risk factors and development or progression of ROP was assessed.Results. Among the 182 eligible infants (median GA, 29.1 weeks; median birth weight (BW), 1028 g), 84 (46%) developed any stage of ROP, of which 45 (25%) required laser treatment. Multivariate analysis using a stepwise method showed that GA (P=0.002; 95% confidence interval (CI), 0.508–0.858), BW (P<0.001; 95% CI, 0.994–0.998), and lower maternal age (P=0.032; 95% CI, 0.819–0.991) were the risk factors for ROP development and GA (P<0.001; 95% CI, 0.387–0.609) and lower maternal age (P=0.012; 95% CI, 0.795–0.973) were for laser treatment. The odds ratio of requiring laser treatment was 3.3 when the maternal age was <33 years.Conclusion. ROP was more likely to be developed and progressed in infants born from younger mother and low GA.


2020 ◽  
Vol 11 (3) ◽  
Author(s):  
Panteha Sadough Shahmirzady ◽  
Abdoulreza Esteghamati ◽  
Azita Sadough ◽  
Fatemeh Sarvi

Background: Congenital anomalies are a physical impairment that occurring to baby at birth. About 10% of anomalies are caused by teratogenic effect, including chemicals, viruses, physical agents, and medications. Objectives: This study was conducted to determine the risk factors of congenital anomalies in newborns. Methods: 332 infants with congenital anomalies (case group) and 332 healthy infants (control group) were compared in this case-control study, which was conducted in Akbar Abadi Hospital from April 2016 to April 2017, on infants who are diagnosed with congenital anomalies, based on a first pediatric examination. The data obtained from these infants were analyzed, based on questionnaires and clinical records. Results: The adjusted odds ratio (OR) estimate of congenital anomalies were 1.045 for increasing maternal age, 2.47 for consanguineous parents, 4.42 for positive maternal disease (hypertension, Diabetes, hyperthyroidism and hypothyroidism) compared to negative maternal disease, 1.92 for cesarean section compared to natural vaginal delivery, 3.02 for positive history of abortion compared to negative history of abortion, 1.136 for father’s age, 2.47 for smoking mothers compared to non-smoking mothers, 3.27 for mothers with the history of having child with abnormality compared to mothers who did not have child with abnormality, and 0.91for gestational age. Conclusions: maternal disease, the history of having child with abnormality, and the history of abortion were the most effective factors in anomalies. In the next step, the consanguineous parents, smoking, the type of delivery, and father’s age were important risk factors. Finally, maternal age and gestational age had significant effect on anomaly.


2020 ◽  
Vol 10 (30) ◽  
pp. 98-105
Author(s):  
Luciane Dos Santos da Silva ◽  
Maria Hulda Lopes dos Santos ◽  
Rosane Pereira Martins ◽  
Nilson Dos Santos Loiola

Estudar a natimortalidade é importante por avaliar a vida intra-uterina e refletir possíveis agravos ocorridos na gestação. Objetivou-se estudar os fatores de riscos associados à natimortalidade ocorrida no Hospital Materno Infantil de Barra do Corda - MA de 2017 à 2018. A pesquisa bibliográfica foi realizada em bases indexadas. Demais dados foram obtidos nos prontuários de atendimento do hospital e tabulados nos softwares Excel e BioEstat 5.0. Evidenciou-se que o preenchimento dos prontuários de atendimento ocorreu de forma deficiente, principalmente com relação ao pré-natal e às informações sociodemográficas. Dentre os 70 casos analisados 28 ocorreram entre indígenas, a idade gestacional média dos conceptos foi de 34,6 semanas e houve um maior número de casos em gestantes com 21 anos. Concluiu-se que há a necessidade de rever os procedimentos de atendimento, bem como intensificar as ações de realização e acompanhamento pré-natal, principalmente nas áreas indígenas.Descritores: Morte Fetal, Fatores de Risco, Epidemiologia. Natimortality at the children’s maternal hospital of Barra do Corda-MAAbstract: Studying perinatal mortality is important because it evaluates intrauterine life and reflects possible problems occurring during the pregnancy. The objective of this study was to study the risk factors associated with perinatal mortality occurred at the Barra do Corda Maternal and Child Hospital - MA from 2017 to 2018. The bibliographic research was performed in indexed databases. Other data were obtained from the hospital's medical records and tabulated in Excel and BioEstat 5.0 software. It was evidenced that the filling of the medical records occurred in a poorly way, especially regarding prenatal care and sociodemographic information. Among the 70 cases analyzed 28 occurred among indigenous, the average gestational age of the concepts was 34.6 weeks and there was a higher number of cases in 21-year-old pregnant women. It was concluded that there is a need to review the care procedures, as well as intensify the actions of prenatal care and monitoring, especially in indigenous areas.Descriptors: Fetal Death, Risk Factors, Epidemiology. Natimortalidad en el hospital materno infantil Barra do Corda-MAResumen: Estudiar la muerte fetal es importante porque evalúa la vida intrauterina y refleja los posibles problemas que ocurren durante el embarazo. El objetivo de este estudio fue estudiar los factores de riesgo asociados con la muerte fetal ocurridos en el Hospital Materno Infantil Barra do Corda - MA de 2017 a 2018. La búsqueda bibliográfica se realizó en bases de datos indexadas. Otros datos se obtuvieron de los registros de atención hospitalaria y se tabularon en el software Excel y BioEstat 5.0. Se evidenció que el llenado de los registros médicos se produjo de manera deficiente, especialmente con respecto a la atención prenatal y la información sociodemográfica. Entre los 70 casos analizados, 28 ocurrieron entre mujeres indígenas, la edad gestacional promedio de la descendencia fue de 34.6 semanas y hubo un mayor número de casos en mujeres embarazadas de 21 años. Se concluyó que es necesario revisar los procedimientos de atención, así como intensificar las acciones de atención prenatal y monitoreo, especialmente en áreas indígenas.Descriptores: Muerte Fetal, Factores de Riesgo, Epidemiologia.


2011 ◽  
Vol 11 (4) ◽  
pp. 397-403 ◽  
Author(s):  
Eugênio Grillo ◽  
Paulo Fontoura Freitas

OBJECTIVES: to investigate pre-gestational risk factors for spontaneous preterm birth and, the role of smoking and its cumulative effects on prematurity. METHODS: a case-control study analyzed a data set of all births occurring in a tertiary maternity hospital between April 2002 and July 2004. Spontaneous preterm births of single and live newborns without malformations were selected as cases. Controls were all the term births of live and single newborns without malformations during the same period. Three outcomes were studied: all preterm births (<37 weeks), less than 35 weeks and less than 32 weeks of gestational age. Logistic regression was used to obtain the independent effect of pre-gestational risk factors. RESULTS: maternal age of less than 20 years, low schooling, low maternal pre-gestational body mass index and smoking showed significant, independent association with spontaneous preterm birth for the three outcomes. For all these risk factors, excepting maternal smoking, odds ratios increased with decreasing gestational age at birth and this trend was significant for low maternal age and low pre-gestational body mass index. CONCLUSIONS: the cumulative effects of smoking calls for the need to encourage smoking cessation among pregnant women, especially those who are underweight and in the older age groups, because of the increased risk of delivering premature babies.


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