Exposure assessment of the consumers living in Mount Lebanon directorate to antibiotics through medication and red meat intake: A cross-sectional study

Background and Aim: The misuse and abuse of antibiotics by human and in animal production are leading to serious threats to global health. This study aimed to assess the dietary exposure of Lebanese consumers to antibiotic residues from the consumption of meat and compare it to that from medication intake. Materials and Methods: Beef samples (n=61) were collected and analyzed for penicillin residues using enzyme-linked immunosorbent assay and high-performance liquid chromatography. A cross-sectional study recruited 500 participants living in Mount Lebanon, using an interviewer-based questionnaire. The dietary exposure assessment was calculated following the tiered assessment approach. Results: The results showed that only 44% of the participants reported using antibiotic on doctor's prescription. Participants with good antibiotic knowledge (6-7/7) are significantly less likely to change antibiotic during treatment and would better use them as compared to those with lower knowledge (p=0.000). Those with lower education and monthly household income are more likely to improperly use antibiotics as compared to those with higher education and income. Penicillin -containing antibiotics were among the most used medications. On the other hand, the prevalence of penicillin residues in the meat samples was 21.3%, though none was above the maximum residue level. The dietary exposure to penicillin through meat consumption was equivalent to 88.3%, 31.9%, and 5.7% of the acceptable daily intake, using Tier 1, 2, and 3 approaches, respectively. Males, single, obese participants, and those with household income below 999,000 Lebanese pound were significantly more exposed to penicillin as compared to other participants due to their high meat consumption. Conclusion: These findings will provide insight into designing future targeted awareness interventions and adapted policies as efforts toward improving rational use and intake of antibiotics for preventing the development of antibiotic resistance.

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Association between socioeconomic status and dental caries among Chinese preschool children: a cross-sectional national study

BMJ Open ◽

10.1136/bmjopen-2020-042908 ◽

2021 ◽

Vol 11 (5) ◽

pp. e042908

Author(s):

Tingting Zhang ◽

Jialan Hong ◽

Xueting Yu ◽

Qiulin Liu ◽

Andi Li ◽

...

Keyword(s):

Socioeconomic Status ◽

Preschool Children ◽

Oral Health ◽

Dental Caries ◽

Household Income ◽

Parental Education ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Index Of Inequality

ObjectivesSocioeconomic inequalities in oral health are often neglected in oral health promotion. This cross-sectional study assessed the association between dental caries and socioeconomic status (SES) among preschool children in China.DesignCross-sectional study.SettingData from the Fourth National Oral Health Survey of China (2015), comprising of 40 360 children aged 3–5 years was used.MethodsDental caries indicators including prevalence of dental caries, dental pain experience and number of decayed, missing and filling teeth (dmft). SES indicators included parental education and household income. The associations between SES and dental caries were analysed by using negative binomial regression or Poisson regression models according to data distribution. Relative and absolute inequalities in dental caries were quantified by using the Relative Index of Inequality (RII) and Slope Index of Inequality (SII), respectively.ResultsThere were significant associations between SES and prevalence of dental caries and dmft (p<0.001). Children from lower educated (RII 1.36, 95% CI 1.3 to 1.43; SII 0.97, 95% CI 0.81 to 1.13) and lower household income (RII 1.17, 95% CI 1.11 to 1.24; SII 0.55, 95% CI 0.35 to 0.75) families had higher dmft than those from well-educated and most affluent families. Relative and absolute inequalities in dental caries were larger in urban areas by household income, and in rural areas by parental education.ConclusionsAssociation between dental caries and SES was demonstrated and socioeconomic inequalities in dental caries existed among Chinese preschool children.

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Evaluation of the Blood Level of Adiponectin in Pregnant Adolescents

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0041-1730288 ◽

2021 ◽

Vol 43 (06) ◽

pp. 429-435

Author(s):

Elaine Cristina Rocha Pádua ◽

Silvia Daher ◽

Isa de Pádua Cintra Sampaio ◽

Edward Araujo Júnior ◽

Cristina Falbo Guazzelli

Keyword(s):

Serum Levels ◽

Cross Sectional Study ◽

Serum Adiponectin ◽

Enzyme Linked Immunosorbent Assay ◽

Sectional Study ◽

Pregnant Adolescents ◽

Cross Sectional ◽

Adolescent Group ◽

Gestational Weight ◽

Intergroup Comparison

Abstract Objective To evaluate serum levels of adiponectin in pregnant adolescents between 30 and 36 weeks of gestation. Method: A prospective cross-sectional study enrolled 67 normal pregnant women between 30 and 36 weeks of gestation and eutrophic (body mass index [BMI]: 18.5–25 kg/m2), of which 36 were adolescents (< 20 years old) and 31 adults (≥ 20 years old). Serum adiponectin levels were determined by enzyme-linked immunosorbent assay (ELISA). The t-student or Mann-Whitney tests were used for intergroup comparison. Results Pregnant adolescents showed significantly higher serum adiponectin concentrations compared with pregnant adults (p = 0.04). No differences were observed in adiponectin levels in younger pregnant adolescents (< 16 years old) compared with older pregnant adolescents (≥ 16 years old). Adiponectin values were divided into 3 subgroups: < 3,000 ng/mL, between 3,000 and 5,000 ng/mL, and > 5,000 ng/mL. Birthweight was significantly higher in women > 5,000 ng/mL when compared with < 3,000 ng/mL in the adolescent group. No association between pregestational adiponectin levels and BMI, gestational weight gain, and gestational age was observed; however, there was a positive relation with birthweight (p = 0.0239). Conclusion Serum adiponectin values in pregnant adolescents between 30 and 36 weeks of gestation were higher compared with pregnant adults; however, no differences between younger and older pregnant adolescents were observed.

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The association between meat consumption and the metabolic syndrome: a cross-sectional study and meta-analysis

British Journal Of Nutrition ◽

10.1017/s0007114521002452 ◽

2021 ◽

pp. 1-15

Author(s):

Khemayanto Hidayat ◽

Wan-Zhan Zhu ◽

Si-Min Peng ◽

Jin-Jin Ren ◽

Meng-Lan Lu ◽

...

Keyword(s):

Metabolic Syndrome ◽

Fish Consumption ◽

Meta Analysis ◽

Meat Consumption ◽

Cross Sectional Study ◽

Red Meat ◽

Inverse Association ◽

Sectional Study ◽

Cross Sectional ◽

The Metabolic Syndrome

Abstract The findings regarding the associations between red meat, fish and poultry consumption, and the metabolic syndrome (Mets) have been inconclusive, and evidence from Chinese populations is scarce. A cross-sectional study was performed to investigate the associations between red meat, fish and poultry consumption, and the prevalence of the Mets and its components among the residents of Suzhou Industrial Park, Suzhou, China. A total of 4424 participants were eligible for the analysis. A logistic regression model was used to estimate the OR and 95 % CI for the prevalence of the Mets and its components according to red meat, fish and poultry consumption. In addition, the data of our cross-sectional study were meta-analysed under a random effects model along with those of published observational studies to generate the summary relative risks (RR) of the associations between the highest v. lowest categories of red meat, fish and poultry consumption and the Mets and its components. In the cross-sectional study, the multivariable-adjusted OR for the highest v. lowest quartiles of consumption was 1·23 (95 % CI 1·02, 1·48) for red meat, 0·83 (95 % CI 0·72, 0·97) for fish and 0·93 (95 % CI 0·74, 1·18) for poultry. In the meta-analysis, the pooled RR for the highest v. lowest categories of consumption was 1·20 (95 % CI 1·06, 1·35) for red meat, 0·88 (95 % CI 0·81, 0·96) for fish and 0·97 (95 % CI 0·85, 1·10) for poultry. The findings of both cross-sectional studies and meta-analyses indicated that the association between fish consumption and the Mets may be partly driven by the inverse association of fish consumption with elevated TAG and reduced HDL-cholesterol and, to a lesser extent, fasting plasma glucose. No clear pattern of associations was observed between red meat or poultry consumption and the components of the Mets. The current findings add weight to the evidence that the Mets may be positively associated with red meat consumption, inversely associated with fish consumption and neutrally associated with poultry consumption.

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Relationship between annual household income and suicidal ideation: a cross-sectional study

Psychology Health & Medicine ◽

10.1080/13548506.2018.1515494 ◽

2018 ◽

Vol 24 (1) ◽

pp. 76-82

Author(s):

Hajime Sueki

Keyword(s):

Suicidal Ideation ◽

Household Income ◽

Cross Sectional Study ◽

Sectional Study ◽

Annual Household Income ◽

Cross Sectional

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Vitamin D Deficiency Is Common in Ghana despite Abundance of Sunlight: A Multicentre Comparative Cross-Sectional Study

Journal of Nutrition and Metabolism ◽

10.1155/2021/9987141 ◽

2021 ◽

Vol 2021 ◽

pp. 1-7

Author(s):

Samuel Asamoah Sakyi ◽

Maxwell Hubert Antwi ◽

Linda Ahenkorah Fondjo ◽

Edwin Ferguson Laing ◽

Richard K. Dadzie Ephraim ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Geographical Area ◽

Daily Intake ◽

Cross Sectional Study ◽

The Body ◽

Sectional Study ◽

Cross Sectional ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D

Background. Vitamin D is a steroid hormone important for the normal functioning of the body. It is produced through skin exposure to sunlight and from the diet. Although Ghana is located in the tropics where sunlight is abundant, factors like culture, diet, skin pigmentation, variation in the ozone layer, and geographical area influence the optimization of vitamin D concentration. It is imperative to evaluate the interplay between sunshine exposure, proinflammatory cytokines, and mediators of vitamin D metabolism and their relationship to vitamin D status in three geographical sections among apparent healthy Ghanaians. Methods and Results. In a cross-sectional study, a total of five hundred (500) healthy blood donors from three geographical areas in Ghana were enrolled. Their age ranged from 17 to 55 years with a mean age of 27.97 ± 8.87 years. The overall prevalence rate of vitamin D deficiency was 43.6% (218/500), with 41.2% (91/221), 45.3% (63/139), and 45.7% (64/140) of vitamin D deficiency being recorded in participants from the Northern Sector (NS), Middle Belt (MB), and Southern Sector (SS), respectively. However, there were no significant differences in the proportions of vitamin D deficiency across various geographical sectors. The median 25-hydroxyvitamin D serum levels were compared among geographical areas (NS, MB, and SS) and there were no significant differences ( P = 0.275 ) after adjusting for confounding factors. 25-Hydroxyvitamin D correlated positively with corrected ionized calcium (rs = 0.622, P ≤ 0.001 ) and phosphorus (rs = 0.299, P ≤ 0.001 ) and negatively correlated with SBP (rs = −0.092, P = 0.039 ), vitamin D binding protein (VDBP) (rs = −0.421, P ≤ 0.001 ), intact parathyroid hormone (iPTH) (rs = −0.0568, rs ≤ 0.001), IFN-gamma (rs = −0.684, P ≤ 0.001 ), and TNF-alpha (rs = −0.600, P ≤ 0.001 ). After adjusting for possible confounders, not having knowledge about vitamin D foods, taking fewer vitamin D foods, and higher levels of IF-γ and IL-10 were associated with a higher risk of having vitamin D deficiency. Conclusion. The prevalence of 25-hydroxyvitamin D deficiency is high among the general adult population in Ghana despite the abundance of sunlight. Increasing knowledge on vitamin D diet coupled with a daily intake of vitamin D dietary supplements is likely to reduce the risk of developing 25-hydroxyvitamin D deficiency.

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Prevalence and Predictors of Gestational Hypertension: a Cross-Sectional Study among Moroccan Pregnant Women

Périnatalité ◽

10.3166/rmp-2020-0106 ◽

2021 ◽

Vol 13 (1) ◽

pp. 1-9

Author(s):

A. El Kardoudi ◽

K. Kaoutar ◽

A. Chetoui ◽

K. Boutahar ◽

S. Elmoussaoui ◽

...

Keyword(s):

Pregnant Women ◽

Household Income ◽

Gestational Hypertension ◽

Cross Sectional Study ◽

Health Care Facilities ◽

Sectional Study ◽

Cross Sectional ◽

Primary Health ◽

Care Facilities ◽

Primary Health Care Facilities

The objective of this study was to assess the prevalence of gestational hypertension, and to determine its predictors among pregnant women attending primary health care facilities in Beni Mellal city in Morocco. The prevalence of gestational hypertension was 18.7%. The low monthly household income (Adjusted Odds Ratio (AOR) = 7.874; IC 95% = [1.788–34.67]), gestational age less than 37 weeks (AOR = 6.860; IC 95% = [1.285–36.626]), limited knowledge on gestational hypertension (AOR = 12.719; IC 95% = [3.386–47.785]), and primigravidity (AOR = 9.047; IC 95% = [1.595–51.324]), were significantly associated with gestational hypertension.

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Seroprevalence of Coxiella burnetii in sheep flocks in Kaduna State, Northwestern Nigeria

Acta Veterinaria Hungarica ◽

10.1556/004.2021.00034 ◽

2021 ◽

Author(s):

Shuaibu Gidado Adamu ◽

Junaidu Kabir ◽

Jarlath Udo Umoh ◽

Mashood Abiola Raji

Keyword(s):

Risk Factors ◽

Coxiella Burnetii ◽

Q Fever ◽

Jugular Vein ◽

Cross Sectional Study ◽

Enzyme Linked Immunosorbent Assay ◽

Sectional Study ◽

High Seroprevalence ◽

Cross Sectional ◽

Significant Difference

Abstract A cross-sectional study was carried out to determine the seroprevalence and risk factors of Q fever in sheep in the northern part of Kaduna State, Nigeria. This study aimed to determine Coxiella burnetii infection and its risk factors in sheep in Kaduna State. A total of 400 blood samples consisting of 259 samples from females and 141 from males were aseptically collected from the jugular vein of sheep from flocks in Kaduna State. The sera obtained were screened for Q fever using an indirect enzyme-linked immunosorbent assay (iELISA). The obtained data were analysed to determine whether there is a relationship between sex, age, and the animals tested. The analysis revealed that 8.0% of the sera was seropositive by iELISA. There was no significant difference in Q fever seropositivity in the study area according to the sex of sheep (P > 0.05). There was a statistically significant difference (P < 0.05) in Q fever seropositivity according to the age of sheep. This study indicated a high seroprevalence of Q fever mainly among female animals and older sheep. Further studies are required to determine the epizootiology of Q fever in the study area more precisely.

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Exposure Assessment of Artificial Sweeteners among Type 2 Diabetic, Overweight and Obese Individuals

The Indian Journal of Nutrition and Dietetics ◽

10.21048/ijnd.2016.53.3.5297 ◽

2016 ◽

Vol 53 (3) ◽

pp. 268

Author(s):

A. Bhagyasri ◽

R. Naveen Kumar ◽

N. Balakrishna ◽

V. Sudershan Rao

Keyword(s):

Exposure Assessment ◽

Daily Intake ◽

Cross Sectional Study ◽

Consumption Pattern ◽

Cross Sectional ◽

Significant Difference ◽

Overweight Group ◽

The Mean ◽

Type 2 Diabetic

In recent years consumption of artificially sweetened foods and beverages became popular in India, with the regulatory formulations to use them in selected foods; their inclusion especially in sweets, biscuits and beverages has increased. There are many concerns rising regarding their safety and is becoming an area of controversy. So an exposure assessment has been carried out to evaluate intake levels among type II diabetic, overweight and obese individuals. A cross-sectional study design was applied and a food frequency questionnaire was used to obtain the information on consumption pattern. Range, standard deviation and mean daily intake levels were calculated and the values were compared with an appropriate Acceptable Daily Intake (ADI). Results indicated that, the mean daily intake levels of aspartame (0.85±0.75) were found to be high among type 2 diabetic individuals whereas sucralose (0.41±0.41) and acesulfame-k (0.07±0.02) were high among overweight group. There was a significant difference (p<0.0001) observed in intake levels among both groups and all the sweeteners were found to be well within the ADI levels.

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Anti-carbamylated protein antibody isotype pattern differs between palindromic rheumatism and rheumatoid arthritis

Therapeutic Advances in Musculoskeletal Disease ◽

10.1177/1759720x20978139 ◽

2020 ◽

Vol 12 ◽

pp. 1759720X2097813

Author(s):

Raul Castellanos-Moreira ◽

Sebastian C. Rodriguez-Garcia ◽

Sonia Cabrera-Villalba ◽

María José Gomara ◽

Georgina Salvador ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Disease Duration ◽

Fetal Calf Serum ◽

Calf Serum ◽

Cross Sectional Study ◽

Enzyme Linked Immunosorbent Assay ◽

Sectional Study ◽

Antibody Isotype ◽

Cross Sectional ◽

Palindromic Rheumatism

Background: A restricted response against citrullinated peptides/proteins, with less isotype usage, has been found in palindromic rheumatism (PR) in comparison with rheumatoid arthritis (RA). We hypothesized that this different antibody response may be observed for other post-translational modified proteins. We compared the prevalence and isotype usage of two specificities of anti-carbamylated peptide/protein antibodies (Anti-CarP) in patients with PR and RA. Methods: Cross-sectional study including 54 patients with pure PR and 53 patients with RA, matched by sex, age, disease duration and ACPA. Anti-CarP specificities were determined by home-made enzyme-linked immunosorbent assay tests using a synthetic chimeric fibrin/filaggrin homocitrullinated peptide (CFFHP) and fetal calf serum (FCS) homocitrullinated protein as antigens. IgG, IgA and IgM isotypes were measured. Results: Anti-CarP were positive (CFFHP or FCS) in 24% and 64% of patients with PR and RA, respectively ( p < 0.005). All Anti-CarP isotype proportions were significantly lower in PR than in RA: Anti-CarP-IgG (24% versus 51%), Anti-CarP-IgA (7% versus 34%) and Anti-CarP-IgM (7% versus 36%). Mean titers of Anti-CarP isotypes were also lower in PR. In Anti-CarP positive patients, the isotype distribution differed between PR and RA: IgG Anti-CarP was used in all PR patients and in 79% of RA patients. By contrast, a significantly lower isotype usage of both IgA (31% versus 53%) and IgM (31% versus 56%) was observed in PR patients. No significant differences in clinical or demographic characteristics were observed according to Anti-CarP status in PR patients, except for a higher prevalence of ACPA and higher mean titers of ACPA and rheumatoid factor in Anti-CarP positive patients. Conclusion: Anti-CarP are found in patients with PR but in a lower proportion and with a different isotype usage from in RA, suggesting a distinct B cell response to homocitrullinated antigens in PR.

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